Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
PhenoMiner Database Result        View data table  |  Download data table  |  View expanded data table        

Generate Chart For    
    (Chart displayed below)
Rat Strains
{{sample.term}}
Measurement Methods
{{method.term}}
Age
{{ageRange}}
Experimental Conditions
     {{ cond }}

Minimum Value:    Maximum Value:    Sex:


 
Options:  View chart  |  Download data table  |  View expanded data table
# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1aCondition 1bCondition 1cCondition 2aCondition 2bCondition 2cCondition 3Condition 4Condition 5
7potassium chloride-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale312.35%controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then potassium chloride solution (100 mmol/l) 84680controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)potassium chloride solution (100 mmol/l)
10potassium chloride-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale301.44%controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then potassium chloride solution (100 mmol/l) 84681controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)potassium chloride solution (100 mmol/l)
7phenylephrine-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale694.94%controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (31.6 umol/l) 84672controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (31.6 umol/l)
10phenylephrine-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale607.58%controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (31.6 umol/l) 84673controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (31.6 umol/l)
6phenylephrine-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale542.39%controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (31.6 umol/l) 84674controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (31.6 umol/l)
6phenylephrine-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale641.52%controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (31.6 umol/l) 84675controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (31.6 umol/l)
7phenylephrine-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale756.89%controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then phenylephrine (31.6 umol/l) 84676controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours)phenylephrine (31.6 umol/l)
9phenylephrine-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale626.89%controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then phenylephrine (31.6 umol/l) 84677controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours)phenylephrine (31.6 umol/l)
6phenylephrine-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale564.27%controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then phenylephrine (31.6 umol/l) 84678controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours)phenylephrine (31.6 umol/l)
5phenylephrine-induced blood vessel contractile force expressed as percent of force at baselineSS/HsdMcwiCrlmale665.33%controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then phenylephrine (31.6 umol/l) 84679controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours)phenylephrine (31.6 umol/l)
7logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.9controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (2 umol/l) then sodium nitroprusside (0.316 umol/l) 84648controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (2 umol/l) sodium nitroprusside (0.316 umol/l)
10logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-8controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then sodium nitroprusside (0.316 umol/l) 84649controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (2 umol/l) sodium nitroprusside (0.316 umol/l)
6logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.9controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then sodium nitroprusside (0.316 umol/l) 84650controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (2 umol/l) sodium nitroprusside (0.316 umol/l)
5logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-8.4controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then sodium nitroprusside (0.316 umol/l) 84651controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (2 umol/l) sodium nitroprusside (0.316 umol/l)
6logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-8.08controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (1 umol/l) then sodium nitroprusside (0-9.5 umol/l) 84668controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (1 umol/l) sodium nitroprusside (0-9.5 umol/l)
10logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.93controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (1 umol/l) then sodium nitroprusside (0-9.5 umol/l) 84669controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (1 umol/l) sodium nitroprusside (0-9.5 umol/l)
7logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-8.37controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (1 umol/l) then sodium nitroprusside (0-9.5 umol/l) 84670controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (1 umol/l) sodium nitroprusside (0-9.5 umol/l)
6logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-8.24controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (1 umol/l) then sodium nitroprusside (0-9.5 umol/l) 84671controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (1 umol/l) sodium nitroprusside (0-9.5 umol/l)
7urine sodium excretion rateSS/HsdMcwiCrlmale6mEq/dcontrolled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days)67667controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)
9urine sodium excretion rateSS/HsdMcwiCrlmale6.4mEq/dcontrolled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days)67668controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)
7urine sodium excretion rateSS/HsdMcwiCrlmale9mEq/dcontrolled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days)67669controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)
4urine sodium excretion rateSS/HsdMcwiCrlmale5.9mEq/dcontrolled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days)67670controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)
7acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale98.24%controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then sodium nitroprusside (0.316 umol/l) 67673controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (2 umol/l) sodium nitroprusside (0.316 umol/l)
6acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale99.71%controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (2 umol/l) then acetylcholine (3.16 umol/l) 69616controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (2 umol/l) acetylcholine (3.16 umol/l)
10acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale99.53%controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then acetylcholine (3.16 umol/l) 69617controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (2 umol/l) acetylcholine (3.16 umol/l)
6acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale100.24%controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then acetylcholine (3.16 umol/l) 69618controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (2 umol/l) acetylcholine (3.16 umol/l)
6acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale100.14%controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then acetylcholine (3.16 umol/l) 69619controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (2 umol/l) acetylcholine (3.16 umol/l)
5acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale94.99%controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then acetylcholine (3.16 umol/l) 69620controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours)acetylcholine (3.16 umol/l)
10acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale64.5%controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (3.16 umol/l) 69621controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (3.16 umol/l)
6acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale91.96%controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (3.16 umol/l) 69622controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (3.16 umol/l)
6acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale92.95%controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (3.16 umol/l) 69623controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (3.16 umol/l)
4acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale70.84%controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (1 umol/l) then acetylcholine (31.6 umol/l) 84652controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (1 umol/l) acetylcholine (31.6 umol/l)
7acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale73.42%controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (1 umol/l) then acetylcholine (31.6 umol/l) 84653controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (1 umol/l) acetylcholine (31.6 umol/l)
4acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale80.04%controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (1 umol/l) then acetylcholine (31.6 umol/l) 84654controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (1 umol/l) acetylcholine (31.6 umol/l)
5acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale78.37%controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (1 umol/l) then acetylcholine (31.6 umol/l) 84655controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (1 umol/l) acetylcholine (31.6 umol/l)
6acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale-19.03%controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (1 umol/l) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then acetylcholine (31.6 umol/l) 84656controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (1 umol/l) NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours)acetylcholine (31.6 umol/l)
10acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale-29.33%controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (1 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (31.6 umol/l) 84657controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (1 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (31.6 umol/l)
7acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale-12.94%controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (1 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (31.6 umol/l) 84658controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (1 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (31.6 umol/l)
6acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale-16.62%controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (1 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (31.6 umol/l) 84659controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (1 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (31.6 umol/l)
N/Aacetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale95.47%controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (1 umol/l) then sodium nitroprusside (3.16 umol/l) 84662controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (1 umol/l) sodium nitroprusside (3.16 umol/l)
10logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.4controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then acetylcholine (0.001-9.5 umol/l) 84641controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (2 umol/l) acetylcholine (0.001-9.5 umol/l)
6logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.2controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then acetylcholine (0.001-9.5 umol/l) 84642controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (2 umol/l) acetylcholine (0.001-9.5 umol/l)
6logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.2controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then acetylcholine (0.001-9.5 umol/l) 84643controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (2 umol/l) acetylcholine (0.001-9.5 umol/l)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.2controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then acetylcholine (0.001-9.5 umol/l) 84644controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours)acetylcholine (0.001-9.5 umol/l)
8logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.3controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (0.001-9.5 umol/l) 84645controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (0.001-9.5 umol/l)
6logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.6controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (0.001-9.5 umol/l) 84646controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (0.001-9.5 umol/l)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.7controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (0.001-9.5 umol/l) 84647controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (0.001-9.5 umol/l)
4logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.1controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then phenylephrine (2 umol/l) then acetylcholine (0.001-9.5 umol/l) 84640controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)phenylephrine (2 umol/l) acetylcholine (0.001-9.5 umol/l)
4logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.31controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then phenylephrine (1 umol/l) then acetylcholine (0-95 umol/l) 84664controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)phenylephrine (1 umol/l) acetylcholine (0-95 umol/l)
7logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.33controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (1 umol/l) then acetylcholine (0-95 umol/l) 84665controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (1 umol/l) acetylcholine (0-95 umol/l)
4logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.49controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (1 umol/l) then acetylcholine (0-95 umol/l) 84666controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (1 umol/l) acetylcholine (0-95 umol/l)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.49controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (1 umol/l) then acetylcholine (0.001-95 umol/l) 84667controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (1 umol/l) acetylcholine (0.001-95 umol/l)
8water drink intake rateSS/HsdMcwiCrlmale30.1ml/dcontrolled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days)67663controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)
9water drink intake rateSS/HsdMcwiCrlmale21.8ml/dcontrolled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days)67664controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)
7water drink intake rateSS/HsdMcwiCrlmale18.4ml/dcontrolled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days)67665controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)
5water drink intake rateSS/HsdMcwiCrlmale30.1ml/dcontrolled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days)67666controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)
6urine total protein excretion rateSS/HsdMcwiCrlmale0.6mg/dcontrolled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days)69612controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)
9urine total protein excretion rateSS/HsdMcwiCrlmale1mg/dcontrolled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days)69613controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)
6urine total protein excretion rateSS/HsdMcwiCrlmale0.7mg/dcontrolled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days)69614controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)
6urine total protein excretion rateSS/HsdMcwiCrlmale0.8mg/dcontrolled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days)69615controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)
7sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale97.36%controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (2 umol/l) then sodium nitroprusside (0.316 umol/l) 67671controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (2 umol/l) sodium nitroprusside (0.316 umol/l)
10sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale96.65%controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then sodium nitroprusside (0.316 umol/l) 67672controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (2 umol/l) sodium nitroprusside (0.316 umol/l)
6sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale98.54%controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then sodium nitroprusside (0.316 umol/l) 67674controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (2 umol/l) sodium nitroprusside (0.316 umol/l)
6sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale98.76%controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (1 umol/l) then sodium nitroprusside (3.16 umol/l) 84660controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (1 umol/l) sodium nitroprusside (3.16 umol/l)
10sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale96.25%controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (1 umol/l) then sodium nitroprusside (3.16 umol/l) 84661controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (1 umol/l) sodium nitroprusside (3.16 umol/l)
6sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselSS/HsdMcwiCrlmale99.39%controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (1 umol/l) then sodium nitroprusside (3.16 umol/l) 84663controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (1 umol/l) sodium nitroprusside (3.16 umol/l)
7tibia lengthSS/HsdMcwiCrlmale4.24cmcontrolled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days)67610controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)
9tibia lengthSS/HsdMcwiCrlmale4.26cmcontrolled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days)67611controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)
6tibia lengthSS/HsdMcwiCrlmale4.3cmcontrolled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days)67612controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)
8tibia lengthSS/HsdMcwiCrlmale4.34cmcontrolled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days)67613controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)
8food intake rateSS/HsdMcwiCrlmale25.2g/dcontrolled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days)67659controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)
9food intake rateSS/HsdMcwiCrlmale21.4g/dcontrolled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days)67660controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)
7food intake rateSS/HsdMcwiCrlmale20.9g/dcontrolled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days)67661controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)
5food intake rateSS/HsdMcwiCrlmale25.4g/dcontrolled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days)67662controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)
8body weight to tibia length ratioSS/HsdMcwiCrlmale97.84g/cmcontrolled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days)67617controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)
9body weight to tibia length ratioSS/HsdMcwiCrlmale98.04g/cmcontrolled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days)67615controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)
6body weight to tibia length ratioSS/HsdMcwiCrlmale96.12g/cmcontrolled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days)67616controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)
7body weight to tibia length ratioSS/HsdMcwiCrlmale100.21g/cmcontrolled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days)67614controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)
7heart weight to tibia length ratioSS/HsdMcwiCrlmale0.37g/cmcontrolled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) then controlled protein content diet (33 %) (for 91 days)67618controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)
9heart weight to tibia length ratioSS/HsdMcwiCrlmale0.34g/cmcontrolled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days)67619controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)
6heart weight to tibia length ratioSS/HsdMcwiCrlmale0.31g/cmcontrolled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) then controlled protein content diet (19 %) (for 91 days)67620controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)
8heart weight to tibia length ratioSS/HsdMcwiCrlmale0.32g/cmcontrolled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days)67621controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)
7both kidneys wet weight to tibia length ratioSS/HsdMcwiCrlmale0.81g/cmcontrolled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) then controlled protein content diet (33 %) (for 91 days)67639controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)
9both kidneys wet weight to tibia length ratioSS/HsdMcwiCrlmale0.73g/cmcontrolled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days)67641controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)
6both kidneys wet weight to tibia length ratioSS/HsdMcwiCrlmale0.71g/cmcontrolled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) then controlled protein content diet (19 %) (for 91 days)67642controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)
8both kidneys wet weight to tibia length ratioSS/HsdMcwiCrlmale0.75g/cmcontrolled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days)67643controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)
7epididymal fat pad weight to tibia length ratioSS/HsdMcwiCrlmale1.17g/cmcontrolled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days)67652controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)
9epididymal fat pad weight to tibia length ratioSS/HsdMcwiCrlmale1.33g/cmcontrolled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days)67653controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)
6epididymal fat pad weight to tibia length ratioSS/HsdMcwiCrlmale1.21g/cmcontrolled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days)67654controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)
8epididymal fat pad weight to tibia length ratioSS/HsdMcwiCrlmale1.21g/cmcontrolled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days)67655controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)

Contact Us |  About Us |  Jobs at RGD