Phenominer Database Results (20 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
SS-Nox4em2Mcwi-/- mean arterial blood pressure controlled sodium content diet (4 %) (for 13 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 4 1/3 systolic pressure + 2/3 diastolic pressure 122.25 mmHg 3.82 7.63 radiotelemetry carotid artery 0 - 66426 717
SS-Nox4em2Mcwi-/- mean arterial blood pressure controlled sodium content diet (0.4 %) (between 50 and 52 days) then controlled sodium content diet (4 %) (for 21 days) Cowley AW Jr, et al., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7. arterial blood pressure trait male 71 days-73 days 9 serial mean 134.0 mmHg 5.0 15.0 intra-aortic thoracic radiotelemetry via carotid cannulation 86400.0 0 98644 2118
SS-Nox4em2Mcwi-/- mean arterial blood pressure controlled sodium content diet (0.4 %) (between 50 and 52 days) Cowley AW Jr, et al., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7. arterial blood pressure trait male 50 days-52 days 9 serial mean 105.0 mmHg 1.0 3.0 intra-aortic thoracic radiotelemetry via carotid cannulation 86400.0 0 98646 2118
SS-Nox4em2Mcwi-/- left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data kidney mass male 70 days-77 days 5 1.37 g 0.07 0.15 post excision weight measurement 0 - 66792 717
SS-Nox4em2Mcwi-/- heart rate controlled sodium content diet (4 %) (for 12 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 3 400.67 beats/min 26.02 45.06 radiotelemetry carotid artery 0 - 67096 717
SS-Nox4em2Mcwi-/- urine albumin excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine albumin amount male 70 days-77 days 5 17.0 mg/d 2.3 5.13 automated urine analysis 0 - 66914 717
SS-Nox4em2Mcwi-/- mean arterial blood pressure controlled sodium content diet (4 %) (for 12 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 3 1/3 systolic pressure + 2/3 diastolic pressure 132.33 mmHg 9.39 16.26 radiotelemetry carotid artery 0 - 66974 717
SS-Nox4em2Mcwi-/- heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data heart mass male 70 days-77 days 5 1.0 g 0.03 0.06 post excision weight measurement 0 - 67036 717
SS-Nox4em2Mcwi-/- heart rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 4 354.25 beats/min 4.33 8.66 radiotelemetry carotid artery 0 - 66607 717
SS-Nox4em2Mcwi-/- heart rate controlled sodium content diet (0.4 %) (between 50 and 52 days) then controlled sodium content diet (4 %) (for 21 days) Cowley AW Jr, et al., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7. heart pumping trait male 71 days-73 days 9 serial mean 409.0 beats/min 4.0 12.0 intra-aortic thoracic radiotelemetry via carotid cannulation 86400.0 0 98640 2118
SS-Nox4em2Mcwi-/- mean arterial blood pressure controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 4 /3 systolic pressure + 2/3 diastolic pressure 118.75 mmHg 1.8 3.59 radiotelemetry carotid artery 0 - 66486 717
SS-Nox4em2Mcwi-/- right kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data kidney mass male 70 days-77 days 5 1.35 g 0.05 0.12 post excision weight measurement 0 - 66244 717
SS-Nox4em2Mcwi-/- urine creatinine excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine creatinine amount male 70 days-77 days 5 10.89 mg/d 0.69 1.53 automated urine analysis 0 - 66730 717
SS-Nox4em2Mcwi-/- urine total protein excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data total urine protein amount male 70 days-77 days 5 58.13 mg/d 6.23 13.93 automated urine analysis 0 - 66547 717
SS-Nox4em2Mcwi-/- heart rate controlled sodium content diet (0.4 %) (between 50 and 52 days) Cowley AW Jr, et al., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7. heart pumping trait male 50 days-52 days 9 serial mean 455.0 beats/min 3.0 9.0 intra-aortic thoracic radiotelemetry via carotid cannulation 86400.0 0 98642 2118
SS-Nox4em2Mcwi-/- heart rate controlled sodium content diet (4 %) (for 11 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 3 385.67 beats/min 12.41 21.5 radiotelemetry carotid artery 0 - 67158 717
SS-Nox4em2Mcwi-/- heart rate controlled sodium content diet (4 %) (for 13 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 4 381.25 beats/min 6.61 13.23 radiotelemetry carotid artery 0 - 66366 717
SS-Nox4em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70 days-77 days 5 9.51 mEq/d 0.72 1.61 automated urine analysis 0 - 66853 717
SS-Nox4em2Mcwi-/- body weight controlled sodium content diet (4 %) (for 10 days) PhysGen Knockout data body mass male 70 days-77 days 5 311.8 g 15.4 34.3 whole body digital scale 0 - 66306 717
SS-Nox4em2Mcwi-/- mean arterial blood pressure controlled sodium content diet (4 %) (for 11 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 3 1/3 systolic pressure + 2/3 diastolic pressure 123.67 mmHg 6.33 10.97 radiotelemetry carotid artery 0 - 66669 717