SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
heart rate |
controlled sodium content diet (4 %) (for 11 days) |
PhysGen Knockout data |
heart pumping trait |
male |
70 days-77 days |
6 |
|
405.5 |
beats/min |
10.21 |
25.02 |
radiotelemetry |
carotid artery |
|
0 |
- |
67170 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
heart rate |
controlled sodium content diet (4 %) (for 12 days) |
PhysGen Knockout data |
heart pumping trait |
male |
70 days-77 days |
6 |
|
391.33 |
beats/min |
10.75 |
26.33 |
radiotelemetry |
carotid artery |
|
0 |
- |
67108 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
mean arterial blood pressure |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
arterial blood pressure trait |
male |
70 days-77 days |
6 |
/3 systolic pressure + 2/3 diastolic pressure |
125.17 |
mmHg |
6.23 |
15.26 |
radiotelemetry |
carotid artery |
|
0 |
- |
66498 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
heart rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart pumping trait |
male |
70 days-77 days |
6 |
|
368.17 |
beats/min |
6.18 |
15.14 |
radiotelemetry |
carotid artery |
|
0 |
- |
66619 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
7 |
|
1.08 |
g |
0.04 |
0.11 |
post excision weight measurement |
|
|
0 |
- |
67048 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
urine creatinine excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine creatinine amount |
male |
70 days-77 days |
7 |
|
11.76 |
mg/d |
0.57 |
1.51 |
automated urine analysis |
|
|
0 |
- |
66742 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
7 |
|
1.45 |
g |
0.06 |
0.15 |
post excision weight measurement |
|
|
0 |
- |
66256 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
mean arterial blood pressure |
controlled sodium content diet (4 %) (for 13 days) |
PhysGen Knockout data |
arterial blood pressure trait |
male |
70 days-77 days |
6 |
1/3 systolic pressure + 2/3 diastolic pressure |
119.83 |
mmHg |
4.19 |
10.26 |
radiotelemetry |
carotid artery |
|
0 |
- |
66438 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
urine sodium excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine sodium amount |
male |
70 days-77 days |
7 |
|
7.84 |
mEq/d |
1.38 |
3.66 |
automated urine analysis |
|
|
0 |
- |
66865 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
mean arterial blood pressure |
controlled sodium content diet (4 %) (for 11 days) |
PhysGen Knockout data |
arterial blood pressure trait |
male |
70 days-77 days |
6 |
1/3 systolic pressure + 2/3 diastolic pressure |
124.67 |
mmHg |
2.17 |
5.32 |
radiotelemetry |
carotid artery |
|
0 |
- |
66681 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
heart rate |
controlled sodium content diet (4 %) (for 13 days) |
PhysGen Knockout data |
heart pumping trait |
male |
70 days-77 days |
6 |
|
387.17 |
beats/min |
4.01 |
9.83 |
radiotelemetry |
carotid artery |
|
0 |
- |
66378 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
7 |
|
66.78 |
mg/d |
4.63 |
12.26 |
automated urine analysis |
|
|
0 |
- |
66926 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
mean arterial blood pressure |
controlled sodium content diet (4 %) (for 12 days) |
PhysGen Knockout data |
arterial blood pressure trait |
male |
70 days-77 days |
6 |
1/3 systolic pressure + 2/3 diastolic pressure |
121.5 |
mmHg |
1.31 |
3.21 |
radiotelemetry |
carotid artery |
|
0 |
- |
66986 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
body weight |
controlled sodium content diet (4 %) (for 10 days) |
PhysGen Knockout data |
body mass |
male |
70 days-77 days |
8 |
|
309.4 |
g |
10.5 |
29.8 |
whole body digital scale |
|
|
0 |
- |
66318 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
7 |
|
1.54 |
g |
0.11 |
0.29 |
post excision weight measurement |
|
|
0 |
- |
66804 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi-/- |
urine total protein excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
total urine protein amount |
male |
70 days-77 days |
7 |
|
132.1 |
mg/d |
10.01 |
26.5 |
automated urine analysis |
|
|
0 |
- |
66559 |
717 |