F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
heart left ventricle wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
heart left ventricle mass |
female |
70 days-84 days |
2 |
0.38 |
g |
0.01 |
0.01 |
digital scale post excision weight measurement |
|
0 |
|
63790 |
529 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
body weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
body mass |
female |
70 days-84 days |
2 |
173.5 |
g |
6.5 |
9.19 |
whole body digital scale |
|
0 |
|
63646 |
529 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
plasma anion gap |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
ion homeostasis trait |
female |
70 days-84 days |
2 |
23.0 |
mmol/l |
0.0 |
0.0 |
standard blood chemistry panel |
|
0 |
|
61127 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum calcium level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood calcium amount |
female |
70 days-84 days |
2 |
9.0 |
mg/dl |
0.0 |
0.0 |
standard blood chemistry panel |
|
0 |
|
60277 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum albumin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood albumin amount |
female |
70 days-84 days |
2 |
3.7 |
g/dl |
0.2 |
0.28 |
standard blood chemistry panel |
|
0 |
|
61957 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum alkaline phosphatase activity level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood alkaline phosphatase amount |
female |
70 days-84 days |
2 |
103.0 |
U/l |
4.0 |
5.66 |
standard blood chemistry panel |
|
0 |
|
60451 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum aspartate aminotransferase activity level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood aspartate transaminase amount |
female |
70 days-84 days |
2 |
202.0 |
U/l |
44.0 |
62.23 |
standard blood chemistry panel |
|
0 |
|
62029 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum urea nitrogen level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood urea nitrogen amount |
female |
70 days-84 days |
2 |
18.0 |
mg/dl |
1.0 |
1.41 |
standard blood chemistry panel |
|
0 |
|
60205 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
1 |
-6.7 |
null |
|
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
62870 |
528 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70 days-84 days |
1 |
-7.85 |
null |
|
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
EC50 value is moles/liter |
63117 |
528 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
1 |
91.0 |
% |
|
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
62647 |
528 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70 days-84 days |
1 |
0.01 |
umol/l |
|
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
62794 |
528 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
blood eosinophil count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
eosinophil quantity |
female |
70 days-84 days |
2 |
0.03 |
x 1000 cells/ul |
0.03 |
0.04 |
automated blood cell counting method |
|
0 |
|
62265 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
blood monocyte count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
monocyte quantity |
female |
70 days-84 days |
2 |
0.04 |
x 1000 cells/ul |
0.04 |
0.06 |
automated blood cell counting method |
|
0 |
|
61733 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum sodium level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood sodium amount |
female |
70 days-84 days |
2 |
138.0 |
mmol/l |
1.0 |
1.41 |
flame atomic emission spectrometry |
|
0 |
|
61835 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
total white blood cell count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
leukocyte quantity |
female |
70 days-84 days |
2 |
6.75 |
x 1000 cells/ul |
0.95 |
1.34 |
automated blood cell counting method |
|
0 |
|
61425 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum chloride level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood chloride amount |
female |
70 days-84 days |
2 |
97.5 |
mmol/l |
0.5 |
0.71 |
standard blood chemistry panel |
|
0 |
|
62347 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum bicarbonate level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood bicarbonate amount |
female |
70 days-84 days |
2 |
21.5 |
mmol/l |
1.5 |
2.12 |
standard blood chemistry panel |
|
0 |
|
61661 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum glucose level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood glucose amount |
female |
70 days-84 days |
2 |
148.0 |
mg/dl |
3.0 |
4.24 |
standard blood chemistry panel |
|
0 |
|
62511 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
1 |
1.98 |
E-7mole |
|
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
63047 |
528 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
blood neutrophil count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
neutrophil quantity |
female |
70 days-84 days |
2 |
1.15 |
x 1000 cells/ul |
0.63 |
0.88 |
automated blood cell counting method |
|
0 |
|
60891 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum total protein level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood total protein amount |
female |
70 days-84 days |
2 |
5.9 |
g/dl |
0.3 |
0.42 |
standard blood chemistry panel |
|
0 |
|
61281 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
body length, nose to tail |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
body length |
female |
70 days-84 days |
2 |
34.5 |
cm |
0.5 |
0.71 |
in vivo ruler method |
|
0 |
|
63718 |
529 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
mean corpuscular hemoglobin |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood hemoglobin amount |
female |
70 days-84 days |
2 |
17.95 |
pg |
0.05 |
0.07 |
automated blood cell counting method |
|
0 |
|
60523 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
body weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Vascular data |
body mass |
female |
70 days-84 days |
2 |
173.5 |
g |
6.5 |
9.19 |
whole body digital scale |
|
0 |
|
62960 |
528 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
kidney mass |
female |
70 days-84 days |
2 |
0.61 |
g |
0.0 |
0.0 |
digital scale post excision weight measurement |
|
0 |
|
63400 |
529 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
body length, nose to rump |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
body length |
female |
70 days-84 days |
2 |
20.0 |
cm |
0.0 |
0.0 |
in vivo ruler method |
|
0 |
|
63564 |
529 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
heart right ventricle wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
heart right ventricle mass |
female |
70 days-84 days |
2 |
0.11 |
g |
0.0 |
0.0 |
digital scale post excision weight measurement |
|
0 |
|
63328 |
529 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
blood lymphocyte count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
lymphocyte quantity |
female |
70 days-84 days |
2 |
5.54 |
x 1000 cells/ul |
0.32 |
0.45 |
automated blood cell counting method |
|
0 |
|
62111 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
maximum contractile force per wet weight of aorta |
controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70 days-84 days |
1 |
0.56 |
g/mg |
|
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
|
63186 |
528 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
hematocrit |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
erythrocyte quantity |
female |
70 days-84 days |
2 |
44.4 |
% |
0.4 |
0.57 |
automated blood cell counting method |
|
0 |
|
60687 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen General data |
heart mass |
female |
70 days-84 days |
2 |
0.6 |
g |
0.02 |
0.03 |
digital scale post excision weight measurement |
|
0 |
|
63472 |
529 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum globulin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood globulin amount |
female |
70 days-84 days |
2 |
2.2 |
g/dl |
0.1 |
0.14 |
standard blood chemistry panel |
|
0 |
replaced obsolete serum globulin level term, 1/19/2016 |
60973 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
mean corpuscular hemoglobin concentration |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood hemoglobin amount |
female |
70 days-84 days |
2 |
31.8 |
g/dl |
0.0 |
0.0 |
automated blood cell counting method |
|
0 |
|
61199 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum potassium level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood potassium amount |
female |
70 days-84 days |
2 |
3.55 |
mmol/l |
0.05 |
0.07 |
flame atomic emission spectrometry |
|
0 |
|
61353 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum total bilirubin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood bilirubin amount |
female |
70 days-84 days |
2 |
0.2 |
mg/dl |
0.0 |
0.0 |
standard blood chemistry panel |
|
0 |
|
62183 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
red blood cell count |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
erythrocyte quantity |
female |
70 days-84 days |
2 |
7.87 |
x 10E6 cells/ul |
0.09 |
0.12 |
automated blood cell counting method |
|
0 |
|
60605 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum total cholesterol level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood cholesterol amount |
female |
70 days-84 days |
2 |
77.0 |
mg/dl |
5.0 |
7.07 |
standard blood chemistry panel |
|
0 |
|
62419 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum phosphate level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood phosphate amount |
female |
70 days-84 days |
2 |
5.9 |
mg/dl |
0.0 |
0.0 |
standard blood chemistry panel |
|
0 |
|
61589 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
mean corpuscular volume |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
erythrocyte size trait |
female |
70 days-84 days |
2 |
56.5 |
fl |
0.1 |
0.14 |
automated blood cell counting method |
|
0 |
|
60799 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
blood hemoglobin level |
controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood hemoglobin amount |
female |
70 days-84 days |
2 |
14.1 |
g/dl |
0.1 |
0.14 |
automated blood cell counting method |
|
0 |
|
60359 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) |
PhysGen Biochemistry data |
blood creatinine amount |
female |
70 days-84 days |
2 |
0.25 |
mg/dl |
0.05 |
0.07 |
automated plasma creatinine analysis |
|
0 |
|
61055 |
527 |
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi |
serum alanine aminotransferase activity level |
controlled sodium content diet (4 %) then fasting (for 16 hours) |
PhysGen Biochemistry data |
blood alanine transaminase amount |
female |
70 days-84 days |
2 |
46.0 |
U/l |
6.0 |
8.49 |
standard blood chemistry panel |
|
0 |
|
61497 |
527 |