Phenominer Database Results (43 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi heart left ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart left ventricle mass female 70 days-84 days 2 0.38 g 0.01 0.01 digital scale post excision weight measurement 0 63790 529
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data body mass female 70 days-84 days 2 173.5 g 6.5 9.19 whole body digital scale 0 63646 529
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi plasma anion gap controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data ion homeostasis trait female 70 days-84 days 2 23.0 mmol/l 0.0 0.0 standard blood chemistry panel 0 61127 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum calcium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood calcium amount female 70 days-84 days 2 9.0 mg/dl 0.0 0.0 standard blood chemistry panel 0 60277 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum albumin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood albumin amount female 70 days-84 days 2 3.7 g/dl 0.2 0.28 standard blood chemistry panel 0 61957 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum alkaline phosphatase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alkaline phosphatase amount female 70 days-84 days 2 103.0 U/l 4.0 5.66 standard blood chemistry panel 0 60451 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum aspartate aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood aspartate transaminase amount female 70 days-84 days 2 202.0 U/l 44.0 62.23 standard blood chemistry panel 0 62029 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum urea nitrogen level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood urea nitrogen amount female 70 days-84 days 2 18.0 mg/dl 1.0 1.41 standard blood chemistry panel 0 60205 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 1 -6.7 null wire myography using a Digi-Med tissue force analysis system with force transducer 0 62870 528
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 1 -7.85 null wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63117 528
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 1 91.0 % wire myography using a Digi-Med tissue force analysis system with force transducer 0 62647 528
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 1 0.01 umol/l wire myography using a Digi-Med tissue force analysis system with force transducer 0 62794 528
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi blood eosinophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data eosinophil quantity female 70 days-84 days 2 0.03 x 1000 cells/ul 0.03 0.04 automated blood cell counting method 0 62265 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi blood monocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data monocyte quantity female 70 days-84 days 2 0.04 x 1000 cells/ul 0.04 0.06 automated blood cell counting method 0 61733 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70 days-84 days 2 138.0 mmol/l 1.0 1.41 flame atomic emission spectrometry 0 61835 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi total white blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data leukocyte quantity female 70 days-84 days 2 6.75 x 1000 cells/ul 0.95 1.34 automated blood cell counting method 0 61425 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum chloride level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood chloride amount female 70 days-84 days 2 97.5 mmol/l 0.5 0.71 standard blood chemistry panel 0 62347 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum bicarbonate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bicarbonate amount female 70 days-84 days 2 21.5 mmol/l 1.5 2.12 standard blood chemistry panel 0 61661 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum glucose level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood glucose amount female 70 days-84 days 2 148.0 mg/dl 3.0 4.24 standard blood chemistry panel 0 62511 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 1 1.98 E-7mole wire myography using a Digi-Med tissue force analysis system with force transducer 0 63047 528
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi blood neutrophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data neutrophil quantity female 70 days-84 days 2 1.15 x 1000 cells/ul 0.63 0.88 automated blood cell counting method 0 60891 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum total protein level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood total protein amount female 70 days-84 days 2 5.9 g/dl 0.3 0.42 standard blood chemistry panel 0 61281 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi body length, nose to tail controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70 days-84 days 2 34.5 cm 0.5 0.71 in vivo ruler method 0 63718 529
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi mean corpuscular hemoglobin controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70 days-84 days 2 17.95 pg 0.05 0.07 automated blood cell counting method 0 60523 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen Vascular data body mass female 70 days-84 days 2 173.5 g 6.5 9.19 whole body digital scale 0 62960 528
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data kidney mass female 70 days-84 days 2 0.61 g 0.0 0.0 digital scale post excision weight measurement 0 63400 529
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi body length, nose to rump controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70 days-84 days 2 20.0 cm 0.0 0.0 in vivo ruler method 0 63564 529
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi heart right ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart right ventricle mass female 70 days-84 days 2 0.11 g 0.0 0.0 digital scale post excision weight measurement 0 63328 529
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi blood lymphocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data lymphocyte quantity female 70 days-84 days 2 5.54 x 1000 cells/ul 0.32 0.45 automated blood cell counting method 0 62111 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 1 0.56 g/mg wire myography using a Digi-Med tissue force analysis system with force transducer 0 63186 528
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi hematocrit controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70 days-84 days 2 44.4 % 0.4 0.57 automated blood cell counting method 0 60687 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart mass female 70 days-84 days 2 0.6 g 0.02 0.03 digital scale post excision weight measurement 0 63472 529
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum globulin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood globulin amount female 70 days-84 days 2 2.2 g/dl 0.1 0.14 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 60973 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi mean corpuscular hemoglobin concentration controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70 days-84 days 2 31.8 g/dl 0.0 0.0 automated blood cell counting method 0 61199 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70 days-84 days 2 3.55 mmol/l 0.05 0.07 flame atomic emission spectrometry 0 61353 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum total bilirubin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bilirubin amount female 70 days-84 days 2 0.2 mg/dl 0.0 0.0 standard blood chemistry panel 0 62183 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi red blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70 days-84 days 2 7.87 x 10E6 cells/ul 0.09 0.12 automated blood cell counting method 0 60605 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum total cholesterol level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood cholesterol amount female 70 days-84 days 2 77.0 mg/dl 5.0 7.07 standard blood chemistry panel 0 62419 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum phosphate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood phosphate amount female 70 days-84 days 2 5.9 mg/dl 0.0 0.0 standard blood chemistry panel 0 61589 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi mean corpuscular volume controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte size trait female 70 days-84 days 2 56.5 fl 0.1 0.14 automated blood cell counting method 0 60799 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi blood hemoglobin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70 days-84 days 2 14.1 g/dl 0.1 0.14 automated blood cell counting method 0 60359 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi plasma creatinine level controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) PhysGen Biochemistry data blood creatinine amount female 70 days-84 days 2 0.25 mg/dl 0.05 0.07 automated plasma creatinine analysis 0 61055 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum alanine aminotransferase activity level controlled sodium content diet (4 %) then fasting (for 16 hours) PhysGen Biochemistry data blood alanine transaminase amount female 70 days-84 days 2 46.0 U/l 6.0 8.49 standard blood chemistry panel 0 61497 527