Phenominer Database Results (86 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
F344-AbatTn(sb-T2/Bart3)2.163Mcwi body length, nose to tail controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70 days-84 days 5 35.0 cm 0.45 1.0 in vivo ruler method 0 63711 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart mass female 70 days-84 days 5 0.58 g 0.02 0.04 digital scale post excision weight measurement 0 63465 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum glucose level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood glucose amount male 70 days-84 days 3 164.33 mg/dl 54.11 93.72 standard blood chemistry panel 0 62507 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 1 0.0 umol/l wire myography using a Digi-Med tissue force analysis system with force transducer 0 62787 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi mean corpuscular volume controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte size trait female 70 days-84 days 4 55.7 fl 0.27 0.54 automated blood cell counting method 0 60792 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi plasma anion gap controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data ion homeostasis trait male 70 days-84 days 3 27.33 mmol/l 0.33 0.58 standard blood chemistry panel 0 61123 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum total protein level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood total protein amount male 70 days-84 days 3 5.9 g/dl 0.2 0.35 standard blood chemistry panel 0 61277 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi total white blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data leukocyte quantity male 70 days-84 days 3 5.67 x 1000 cells/ul 0.23 0.4 automated blood cell counting method 0 61421 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum bicarbonate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bicarbonate amount male 70 days-84 days 3 19.67 mmol/l 0.67 1.15 standard blood chemistry panel 0 61657 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood lymphocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data lymphocyte quantity female 70 days-84 days 4 3.78 x 1000 cells/ul 0.24 0.48 automated blood cell counting method 0 62104 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data body mass female 70 days-84 days 5 168.0 g 2.77 6.2 whole body digital scale 0 63639 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood hemoglobin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70 days-84 days 4 14.23 g/dl 0.18 0.36 automated blood cell counting method 0 60352 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70 days-84 days 3 4.17 mmol/l 0.27 0.46 flame atomic emission spectrometry 0 61349 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart mass male 70 days-84 days 5 0.87 g 0.02 0.04 digital scale post excision weight measurement 0 63468 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 1 -8.61 null wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63113 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 1 100.0 % wire myography using a Digi-Med tissue force analysis system with force transducer 0 62643 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi hematocrit controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70 days-84 days 4 44.03 % 1.25 2.5 automated blood cell counting method 0 60680 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi plasma anion gap controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data ion homeostasis trait female 70 days-84 days 2 26.0 mmol/l 1.0 1.41 standard blood chemistry panel 0 61120 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum chloride level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood chloride amount male 70 days-84 days 3 97.33 mmol/l 0.67 1.15 standard blood chemistry panel 0 62343 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum total cholesterol level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood cholesterol amount male 70 days-84 days 3 67.67 mg/dl 7.86 13.61 standard blood chemistry panel 0 62415 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum bicarbonate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bicarbonate amount female 70 days-84 days 4 20.25 mmol/l 0.63 1.26 standard blood chemistry panel 0 61654 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum total bilirubin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bilirubin amount male 70 days-84 days 3 0.05 mg/dl 0.0 0.0 standard blood chemistry panel 0 62179 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood eosinophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data eosinophil quantity male 70 days-84 days 3 0.12 x 1000 cells/ul 0.04 0.07 automated blood cell counting method 0 62261 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum alanine aminotransferase activity level controlled sodium content diet (4 %) then fasting (for 16 hours) PhysGen Biochemistry data blood alanine transaminase amount male 70 days-84 days 3 51.0 U/l 3.51 6.08 standard blood chemistry panel 0 61493 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum urea nitrogen level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood urea nitrogen amount female 70 days-84 days 4 17.5 mg/dl 3.18 6.35 standard blood chemistry panel 0 60198 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum urea nitrogen level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood urea nitrogen amount male 70 days-84 days 3 18.67 mg/dl 1.2 2.08 standard blood chemistry panel 0 60201 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum calcium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood calcium amount male 70 days-84 days 3 10.63 mg/dl 0.09 0.15 standard blood chemistry panel 0 60273 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum albumin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood albumin amount male 70 days-84 days 3 3.9 g/dl 0.15 0.26 standard blood chemistry panel 0 61953 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70 days-84 days 4 4.18 mmol/l 0.37 0.73 flame atomic emission spectrometry 0 61346 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi body length, nose to tail controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length male 70 days-84 days 5 39.8 cm 0.58 1.3 in vivo ruler method 0 63714 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi heart right ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart right ventricle mass female 70 days-84 days 5 0.1 g 0.0 0.01 digital scale post excision weight measurement 0 63321 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data kidney mass female 70 days-84 days 5 0.6 g 0.01 0.03 digital scale post excision weight measurement 0 63393 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data kidney mass male 70 days-84 days 5 1.01 g 0.03 0.06 digital scale post excision weight measurement 0 63396 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 1 0.92 g/mg wire myography using a Digi-Med tissue force analysis system with force transducer 0 63179 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 1 30.0 % wire myography using a Digi-Med tissue force analysis system with force transducer 0 62640 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi hematocrit controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity male 70 days-84 days 3 47.17 % 2.16 3.74 automated blood cell counting method 0 60683 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi plasma creatinine level controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) PhysGen Biochemistry data blood creatinine amount female 70 days-84 days 4 0.25 mg/dl 0.03 0.06 automated plasma creatinine analysis 0 61048 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum chloride level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood chloride amount female 70 days-84 days 4 101.75 mmol/l 1.18 2.36 standard blood chemistry panel 0 62340 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70 days-84 days 4 142.25 mmol/l 0.75 1.5 flame atomic emission spectrometry 0 61828 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum total bilirubin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bilirubin amount female 70 days-84 days 4 0.13 mg/dl 0.03 0.05 standard blood chemistry panel 0 62176 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood eosinophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data eosinophil quantity female 70 days-84 days 4 0.0 x 1000 cells/ul 0.0 0.0 automated blood cell counting method 0 62258 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum phosphate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood phosphate amount male 70 days-84 days 3 8.33 mg/dl 0.55 0.95 standard blood chemistry panel 0 61585 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi mean corpuscular hemoglobin controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70 days-84 days 4 18.02 pg 0.23 0.45 automated blood cell counting method 0 60516 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi red blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70 days-84 days 4 7.9 x 10E6 cells/ul 0.19 0.37 automated blood cell counting method 0 60598 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood hemoglobin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70 days-84 days 3 15.07 g/dl 0.61 1.06 automated blood cell counting method 0 60355 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum albumin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood albumin amount female 70 days-84 days 4 3.88 g/dl 0.12 0.24 standard blood chemistry panel 0 61950 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 1 1.92 E-7mole wire myography using a Digi-Med tissue force analysis system with force transducer 0 63043 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi heart right ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart right ventricle mass male 70 days-84 days 5 0.15 g 0.0 0.01 digital scale post excision weight measurement 0 63324 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi body length, nose to rump controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70 days-84 days 5 20.2 cm 0.2 0.45 in vivo ruler method 0 63557 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum glucose level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood glucose amount female 70 days-84 days 4 175.75 mg/dl 22.93 45.86 standard blood chemistry panel 0 62504 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 1 0.0 umol/l wire myography using a Digi-Med tissue force analysis system with force transducer 0 62790 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen Vascular data body mass female 70 days-84 days 3 169.0 g 4.93 8.54 whole body digital scale 0 62953 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi mean corpuscular volume controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte size trait male 70 days-84 days 3 53.27 fl 0.23 0.4 automated blood cell counting method 0 60795 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood neutrophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data neutrophil quantity female 70 days-84 days 4 0.9 x 1000 cells/ul 0.04 0.07 automated blood cell counting method 0 60884 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum globulin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood globulin amount male 70 days-84 days 3 2.0 g/dl 0.06 0.1 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 60969 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum globulin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood globulin amount female 70 days-84 days 4 1.93 g/dl 0.13 0.26 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 60966 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi total white blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data leukocyte quantity female 70 days-84 days 4 4.83 x 1000 cells/ul 0.27 0.54 automated blood cell counting method 0 61418 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum total cholesterol level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood cholesterol amount female 70 days-84 days 4 81.75 mg/dl 5.74 11.47 standard blood chemistry panel 0 62412 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70 days-84 days 3 140.0 mmol/l 0.0 0.0 flame atomic emission spectrometry 0 61831 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum alanine aminotransferase activity level controlled sodium content diet (4 %) then fasting (for 16 hours) PhysGen Biochemistry data blood alanine transaminase amount female 70 days-84 days 4 33.25 U/l 2.32 4.65 standard blood chemistry panel 0 61490 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum calcium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood calcium amount female 70 days-84 days 4 9.82 mg/dl 0.64 1.29 standard blood chemistry panel 0 60270 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum aspartate aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood aspartate transaminase amount female 70 days-84 days 4 141.0 U/l 10.72 21.45 standard blood chemistry panel 0 62022 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum aspartate aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood aspartate transaminase amount male 70 days-84 days 3 210.33 U/l 30.33 52.54 standard blood chemistry panel 0 62025 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi mean corpuscular hemoglobin controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70 days-84 days 3 17.03 pg 0.13 0.23 automated blood cell counting method 0 60519 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum alkaline phosphatase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alkaline phosphatase amount female 70 days-84 days 4 97.5 U/l 6.96 13.92 standard blood chemistry panel 0 60444 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi mean corpuscular hemoglobin concentration controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70 days-84 days 3 32.0 g/dl 0.21 0.36 automated blood cell counting method 0 61195 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 1 2.24 E-7mole wire myography using a Digi-Med tissue force analysis system with force transducer 0 63040 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi body length, nose to rump controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length male 70 days-84 days 5 24.1 cm 0.1 0.22 in vivo ruler method 0 63560 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 1 -8.89 null wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63110 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 1 0.93 g/mg wire myography using a Digi-Med tissue force analysis system with force transducer 0 63182 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 1 -6.65 null wire myography using a Digi-Med tissue force analysis system with force transducer 0 62863 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 1 -6.72 null wire myography using a Digi-Med tissue force analysis system with force transducer 0 62866 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen Vascular data body mass male 70 days-84 days 3 282.67 g 8.67 15.01 whole body digital scale 0 62956 528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi plasma creatinine level controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) PhysGen Biochemistry data blood creatinine amount male 70 days-84 days 3 0.3 mg/dl 0.06 0.1 automated plasma creatinine analysis 0 61051 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum total protein level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood total protein amount female 70 days-84 days 4 5.8 g/dl 0.15 0.29 standard blood chemistry panel 0 61274 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood lymphocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data lymphocyte quantity male 70 days-84 days 3 3.86 x 1000 cells/ul 0.46 0.79 automated blood cell counting method 0 62107 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum phosphate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood phosphate amount female 70 days-84 days 4 7.18 mg/dl 0.42 0.84 standard blood chemistry panel 0 61582 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi red blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity male 70 days-84 days 3 8.86 x 10E6 cells/ul 0.4 0.69 automated blood cell counting method 0 60601 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data body mass male 70 days-84 days 5 281.4 g 4.94 11.04 whole body digital scale 0 63642 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi heart left ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart left ventricle mass female 70 days-84 days 5 0.38 g 0.01 0.02 digital scale post excision weight measurement 0 63783 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi heart left ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart left ventricle mass male 70 days-84 days 5 0.59 g 0.01 0.03 digital scale post excision weight measurement 0 63786 529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum alkaline phosphatase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alkaline phosphatase amount male 70 days-84 days 3 162.67 U/l 10.84 18.77 standard blood chemistry panel 0 60447 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood neutrophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data neutrophil quantity male 70 days-84 days 3 1.45 x 1000 cells/ul 0.21 0.37 automated blood cell counting method 0 60887 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi mean corpuscular hemoglobin concentration controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70 days-84 days 4 32.38 g/dl 0.54 1.08 automated blood cell counting method 0 61192 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood monocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data monocyte quantity male 70 days-84 days 3 0.24 x 1000 cells/ul 0.06 0.11 automated blood cell counting method 0 61729 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi blood monocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data monocyte quantity female 70 days-84 days 4 0.15 x 1000 cells/ul 0.04 0.08 automated blood cell counting method 0 61726 527