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Study IDStudyExperiment NameExperiment NotesStrain Ont IDStrainSexAge# of AnimalsSample NotesClinical Measurement Ont IDPhenotypeFormulaClinical Measurement NotesAverage TypeValueUnitsSEMSDMethod Ont IDMethodMethod SiteMethod DurationMethod NotesPost Insult TypePost Insult Time ValuePost Insult Time UnitConditionsRecord IDCondition 1aCondition 1bCondition 1cCondition 2
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood creatinine amountRS:0000916WKY/NHsdmale0 days8CMO:0000537plasma creatinine level0.35180942mg/dl0.0170.048MMO:0000306plasma creatinine analysis0.0standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99172standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood creatinine amountRS:0000916WKY/NHsdmale0 days7CMO:0000537plasma creatinine level0.30882306mg/dl0.01020.0269MMO:0000306plasma creatinine analysis0.0standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99171standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004091LN/MavRrrcAekmale119 days14CMO:0000009mean arterial blood pressuremean of 15 sec every 5 min for 72 hoursserial mean99.9mmHg1.24.49MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102608standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004090LH/MavRrrcAekmale119 days9CMO:0000009mean arterial blood pressuremean of 15 sec every 5 min for 72 hoursserial mean136.1mmHg1.75.1MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102607standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004091LN/MavRrrcAekmale98 days14CMO:0000009mean arterial blood pressuremean of 15 sec every 5 min for 72 hoursserial mean98.4mmHg1.34.8642MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days)102602standard rat chow (for 98 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004090LH/MavRrrcAekmale98 days9CMO:0000009mean arterial blood pressuremean of 15 sec every 5 min for 72 hoursserial mean122mmHg1.23.6MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days)102601standard rat chow (for 98 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.arterial blood pressure traitRS:0000916WKY/NHsdmale0 days8CMO:0000009mean arterial blood pressure128mmHg3.08.4853MMO:0000577intra-aortic radiotelemetry0.0standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99188standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.arterial blood pressure traitRS:0000916WKY/NHsdmale0 days7CMO:0000009mean arterial blood pressure101mmHg0.92.3812MMO:0000577intra-aortic radiotelemetry0.0standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99187standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood chloride amountRS:0000916WKY/NHsdmale0 days8CMO:0000059plasma chloride level100.5mmol/l0.51.4142MMO:0000037automated blood electrolyte analysis0.0standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99168standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood chloride amountRS:0000916WKY/NHsdmale0 days7CMO:0000059plasma chloride level98.2mmol/l1.12.9103MMO:0000037automated blood electrolyte analysis0.0standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99167standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004091LN/MavRrrcAekmale119 days14CMO:0000004systolic blood pressuremean of 15 sec every 5 min for 72 hoursserial mean116mmHg1.45.2383MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102610standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004090LH/MavRrrcAekmale119 days9CMO:0000004systolic blood pressuremean of 15 sec every 5 min for 72 hoursserial mean161.2mmHg2.16.3MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102609standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004091LN/MavRrrcAekmale98 days14CMO:0000004systolic blood pressuremean of 15 sec every 5 min for 72 hoursserial mean114.5mmHg1.45.2383MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days)102604standard rat chow (for 98 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004090LH/MavRrrcAekmale98 days9CMO:0000004systolic blood pressuremean of 15 sec every 5 min for 72 hoursserial mean147.5mmHg1.44.2MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days)102603standard rat chow (for 98 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.abdominal fat pad massRS:0004091LN/MavRrrcAekmale126 days14CMO:0000088abdominal fat pad weightwh adipose0.72g0.030.1122MMO:0000005post excision weight measurement0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102620standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.abdominal fat pad massRS:0004090LH/MavRrrcAekmale126 days9CMO:0000088abdominal fat pad weightwh adipose1.43g0.090.27MMO:0000005post excision weight measurement0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102619standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3035Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x.kidney massRS:0000677SBH/Yglmale16 days8CMO:0000340both kidneys wet weight to body weight ration=8-152.6g/kg0.070.198MMO:0000005post excision weight measurement0.0sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days)106649sham surgical control condition (for 56 days)water (for 56 days)standard rat chow (for 56 days)
3035Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x.kidney massRS:0000679SBN/Yglmale16 days8CMO:0000340both kidneys wet weight to body weight ration=8-152.4g/kg0.030.0849MMO:0000005post excision weight measurement0.0sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days)106646sham surgical control condition (for 56 days)water (for 56 days)standard rat chow (for 56 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004091LN/MavRrrcAekmale119 days14CMO:0000005diastolic blood pressuremean of 15 sec every 5 min for 72 hoursserial mean86.1mmHg1.14.1158MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102612standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004090LH/MavRrrcAekmale119 days9CMO:0000005diastolic blood pressuremean of 15 sec every 5 min for 72 hoursserial mean113.9mmHg1.64.8MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102611standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004091LN/MavRrrcAekmale98 days14CMO:0000005diastolic blood pressuremean of 15 sec every 5 min for 72 hoursserial mean84.9mmHg1.24.49MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days)102606standard rat chow (for 98 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.arterial blood pressure traitRS:0004090LH/MavRrrcAekmale98 days9CMO:0000005diastolic blood pressuremean of 15 sec every 5 min for 72 hoursserial mean100.8mmHg1.13.3MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days)102605standard rat chow (for 98 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood glucose amountRS:0004091LN/MavRrrcAekmale112 days14CMO:0000042plasma glucose level155.5mg/dl7.728.8108MMO:0000315plasma glucose analysis0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 14 days)102624standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 14 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood glucose amountRS:0004090LH/MavRrrcAekmale112 days9CMO:0000042plasma glucose level141.9mg/dl8.124.3MMO:0000315plasma glucose analysis0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 14 days)102623standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 14 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood glucose amountRS:0004091LN/MavRrrcAekmale84 days14CMO:0000042plasma glucose level149.8mg/dl10.840.4099MMO:0000315plasma glucose analysis0.0standard rat chow (for 84 days)102622standard rat chow (for 84 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood glucose amountRS:0004090LH/MavRrrcAekmale84 days9CMO:0000042plasma glucose level116.5mg/dl5.015.0MMO:0000315plasma glucose analysis0.0standard rat chow (for 84 days)102621standard rat chow (for 84 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood sodium amountRS:0000916WKY/NHsdmale0 days8CMO:0000060plasma sodium level137.8mmol/l2.36.5054MMO:0000037automated blood electrolyte analysis0.0standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99160standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood sodium amountRS:0000916WKY/NHsdmale0 days7CMO:0000060plasma sodium level143.7mmol/l4.411.6413MMO:0000037automated blood electrolyte analysis0.0standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99159standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.heart pumping traitRS:0004091LN/MavRrrcAekmale119 days14CMO:0000002heart rate346.5beats/min2.710.1025MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102616standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.heart pumping traitRS:0004090LH/MavRrrcAekmale119 days9CMO:0000002heart rate319.2beats/min1.85.4MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 21 days)102615standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 21 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.heart pumping traitRS:0004091LN/MavRrrcAekmale98 days14CMO:0000002heart rate359beats/min2.710.1025MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days)102614standard rat chow (for 98 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.heart pumping traitRS:0004090LH/MavRrrcAekmale98 days9CMO:0000002heart rate326.5beats/min2.57.5MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0standard rat chow (for 98 days)102613standard rat chow (for 98 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.glomerular filtration traitRS:0000916WKY/NHsdmale0 days8CMO:0000765creatinine clearance3.1ml/min0.51.4142MMO:0000275urine creatinine analysis0.0standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99180standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.glomerular filtration traitRS:0000916WKY/NHsdmale0 days7CMO:0000765creatinine clearance3.1ml/min0.51.3229MMO:0000275urine creatinine analysis0.0standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99179standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood triglyceride amountRS:0004091LN/MavRrrcAekmale126 days14CMO:0000548plasma triglyceride level0.39mmol/l0.050.1871MMO:0000234plasma triglyceride analysis0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 28 days)102630standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 28 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood triglyceride amountRS:0004090LH/MavRrrcAekmale126 days9CMO:0000548plasma triglyceride level0.91mmol/l0.070.21MMO:0000234plasma triglyceride analysis0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 28 days)102629standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 28 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood triglyceride amountRS:0004091LN/MavRrrcAekmale112 days14CMO:0000548plasma triglyceride level0.4mmol/l0.050.1871MMO:0000234plasma triglyceride analysis0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 14 days)102628standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 14 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood triglyceride amountRS:0004090LH/MavRrrcAekmale112 days9CMO:0000548plasma triglyceride level0.43mmol/l0.050.15MMO:0000234plasma triglyceride analysis0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 14 days)102627standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 14 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood triglyceride amountRS:0004091LN/MavRrrcAekmale84 days14CMO:0000548plasma triglyceride level0.47mmol/l0.090.3367MMO:0000234plasma triglyceride analysis0.0standard rat chow (for 84 days)102626standard rat chow (for 84 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood triglyceride amountRS:0004090LH/MavRrrcAekmale84 days9CMO:0000548plasma triglyceride level0.56mmol/l0.061.8MMO:0000234plasma triglyceride analysis0.0standard rat chow (for 84 days)102625standard rat chow (for 84 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood potassium amountRS:0000916WKY/NHsdmale0 days8CMO:0000061plasma potassium level4.2mmol/l0.30.8485MMO:0000037automated blood electrolyte analysis0.0standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99164standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood potassium amountRS:0000916WKY/NHsdmale0 days7CMO:0000061plasma potassium level3.9mmol/l0.20.5292MMO:0000037automated blood electrolyte analysis0.0standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99163standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
3035Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x.body massRS:0000677SBH/Yglmale16 days8CMO:0000012body weightn=8-15359g3.18.7681MMO:0000016body weighing method0.0sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days)106643sham surgical control condition (for 56 days)water (for 56 days)standard rat chow (for 56 days)
3035Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x.body massRS:0000679SBN/Yglmale16 days8CMO:0000012body weightn=8-15328g5.415.2735MMO:0000016body weighing method0.0sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days)106640sham surgical control condition (for 56 days)water (for 56 days)standard rat chow (for 56 days)
3008Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.body massRS:0004656F344-Hsd11b2em1Jmul+/+female98 days4CMO:0000012body weight190.5g2.55.0MMO:0000016body weighing method0.0standard rat chow104992standard rat chow
3008Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.body massRS:0004653F344-Hsd11b2em1Jmul-/-female98 days5CMO:0000012body weight166.2g2.65.8138MMO:0000016body weighing method0.0standard rat chow104991standard rat chow
3008Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.body massRS:0004656F344-Hsd11b2em1Jmul+/+male98 days9CMO:0000012body weight319.8g6.118.3MMO:0000016body weighing method0.0standard rat chow104990standard rat chow
3008Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.body massRS:0004653F344-Hsd11b2em1Jmul-/-male98 days7CMO:0000012body weight276.7g4.110.8476MMO:0000016body weighing method0.0standard rat chow104989standard rat chow
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood cholesterol amountRS:0004091LN/MavRrrcAekmale126 days14CMO:0000585plasma total cholesterol level71.8146mg/dl6.563724.5591MMO:0000284plasma total cholesterol measurement test0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 28 days)102636standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 28 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood cholesterol amountRS:0004090LH/MavRrrcAekmale126 days9CMO:0000585plasma total cholesterol level81.4671mg/dl5.405416.2162MMO:0000284plasma total cholesterol measurement test0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 28 days)102635standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 28 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood cholesterol amountRS:0004091LN/MavRrrcAekmale112 days14CMO:0000585plasma total cholesterol level42.471mg/dl4.633217.3358MMO:0000284plasma total cholesterol measurement test0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 14 days)102634standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 14 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood cholesterol amountRS:0004090LH/MavRrrcAekmale112 days9CMO:0000585plasma total cholesterol level62.5482mg/dl7.72223.166MMO:0000284plasma total cholesterol measurement test0.0standard rat chow (for 98 days) then controlled sodium content diet (4 %) (for 14 days)102633standard rat chow (for 98 days)controlled sodium content diet (4 %) (for 14 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood cholesterol amountRS:0004091LN/MavRrrcAekmale84 days14CMO:0000585plasma total cholesterol level42.0849mg/dl3.86114.4465MMO:0000284plasma total cholesterol measurement test0.0standard rat chow (for 84 days)102632standard rat chow (for 84 days)
3014Wang J, et al., Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. doi: 10.1161/CIRCGENETICS.114.000520. Epub 2015 Jan 8.blood cholesterol amountRS:0004090LH/MavRrrcAekmale84 days9CMO:0000585plasma total cholesterol level59.4594mg/dl6.949820.8494MMO:0000284plasma total cholesterol measurement test0.0standard rat chow (for 84 days)102631standard rat chow (for 84 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin potassium amountRS:0000916WKY/NHsdmale0 days8CMO:0002773skin potassium level to skin water level ratioskin k/h2o75mmol/l1.85.0912MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99156standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin potassium amountRS:0000916WKY/NHsdmale0 days7CMO:0002773skin potassium level to skin water level ratioskin k/h2o80mmol/l1.12.9103MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99155standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin mineral amountRS:0000916WKY/NHsdmale0 days8CMO:0002772skin potassium level plus skin sodium level to skin water level ratioskin na+k/h2o0.1670.0030.0085MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99144standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin mineral amountRS:0000916WKY/NHsdmale0 days7CMO:0002772skin potassium level plus skin sodium level to skin water level ratioskin na+k/h2o0.170.0010.0026MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99143standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood cystatin C amountRS:0000916WKY/NHsdmale0 days8CMO:0002778plasma cystatin C levelplasma cystatin c4.7mg/l0.30.8485MMO:0000352automated plasma protein analysis0.0standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99176standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.blood cystatin C amountRS:0000916WKY/NHsdmale0 days7CMO:0002778plasma cystatin C level4mg/l0.61.5875MMO:0000352automated plasma protein analysis0.0standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99175standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.urine sodium amountRS:0000916WKY/NHsdmale0 days8CMO:0000760urine sodium excretion rate1.1mEq/d0.10.2828MMO:0000434urine sodium analysis0.0standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99184standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.urine sodium amountRS:0000916WKY/NHsdmale0 days7CMO:0000760urine sodium excretion ratemmol/d1mEq/d0.20.5292MMO:0000434urine sodium analysis0.0standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99183standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin water amountRS:0000916WKY/NHsdmale0 days8CMO:0002771skin water level to skin dry weight ratioskin h2o ml/g1.208ml/g0.0190.0537MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99140standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin water amountRS:0000916WKY/NHsdmale0 days7CMO:0002771skin water level to skin dry weight ratioskin h2o ml/g1.223ml/g0.0320.0847MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then sunitinib (0.5 ml) (for 8 days)99139standard rat chow (for 8 days)sunitinib (0.5 ml) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin sodium amountRS:0000916WKY/NHsdmale0 days8CMO:0002769skin sodium level to skin dry weight ratiommol/g0.112REQUEST NEW VALUE0.0020.0057MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99132standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin sodium amountRS:0000916WKY/NHsdmale0 days7CMO:0002769skin sodium level to skin dry weight ratiommol/g0.11REQUEST NEW VALUE0.0030.0079MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99131standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin chloride amountRS:0000916WKY/NHsdmale0 days8CMO:0002770skin chloride level to skin dry weight ratioskin cl mmol/g0.052mmol/g0.0030.0085MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99136standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin chloride amountRS:0000916WKY/NHsdmale0 days7CMO:0002770skin chloride level to skin dry weight ratioskin cl mmol/g0.051mmol/g0.0030.0079MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99135standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin chloride amountRS:0000916WKY/NHsdmale0 days8CMO:0002775skin chloride level to skin water level ratioskin cl/h2o43mmol/l1.54.2426MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99152standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin chloride amountRS:0000916WKY/NHsdmale0 days7CMO:0002775skin chloride level to skin water level ratioskin cl/h2o42mmol/l2.46.3498MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99151standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin chloride amountRS:0000916WKY/NHsdmale0 days8CMO:0002775skin chloride level to skin water level ratioskin na/h2o92mmol/l1.54.2426MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)99148standard rat chow (for 8 days)sunitinib (7 mg/kg/d) (for 8 days)
2238Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.skin chloride amountRS:0000916WKY/NHsdmale0 days7CMO:0002775skin chloride level to skin water level ratioskin na/h2o90mmol/l0.82.1166MMO:0000584ex vivo analysis of atomic composition following dry ashing0.0ashed skinstandard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)99147standard rat chow (for 8 days)vehicle control condition (0.5 ml) (for 8 days)