Phenominer Database Results (152 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Experiment Notes Record ID Study ID
FHH-Chr 2BN/Mcwi tidal volume air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 0.23 ml 0.01 0.04 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13910 381
FHH-Chr 2BN/Mcwi minute ventilation air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 40.62 ml/min 4.8 15.17 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18649 381
FHH-Chr 2BN/Mcwi time to peak heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 10 1256.8 s 42.07 133.05 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50214 461
FHH-Chr 2BN/Mcwi hematocrit air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77 days-91 days 8 56.6 % 1.01 2.84 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38983 401
FHH-Chr 2BN/Mcwi serum albumin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount female 77 days-91 days 8 3.36 g/dl 0.09 0.24 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42220 401
FHH-Chr 2BN/Mcwi serum chloride level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount female 77 days-91 days 8 108.0 mmol/l 0.82 2.33 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39104 401
FHH-Chr 2BN/Mcwi blood lymphocyte count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity female 77 days-91 days 8 5.96 x 1000 cells/ul 1.19 3.38 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41490 401
FHH-Chr 2BN/Mcwi serum glucose level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount female 77 days-91 days 7 173.14 mg/dl 7.77 20.56 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38517 401
FHH-Chr 2BN/Mcwi plasma anion gap air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait female 77 days-91 days 8 20.63 mmol/l 0.98 2.77 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38248 401
FHH-Chr 2BN/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait female 77 days-91 days 9 0.03 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 58476 526
FHH-Chr 2BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 0.54 IU/g 0.2 0.57 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47442 461
FHH-Chr 2BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 5.07 mmHg 0.58 1.65 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47189 461
FHH-Chr 2BN/Mcwi serum total protein level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount male 77 days-91 days 8 5.28 g/dl 0.08 0.23 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36954 401
FHH-Chr 2BN/Mcwi serum total cholesterol level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount male 77 days-91 days 8 79.25 mg/dl 3.54 10.03 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37089 401
FHH-Chr 2BN/Mcwi respiration rate air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 180.21 breaths/min 6.05 19.13 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18257 381
FHH-Chr 2BN/Mcwi minute ventilation air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 36.64 ml/min 3.36 10.64 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 20200 381
FHH-Chr 2BN/Mcwi serum aspartate aminotransferase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount male 77 days-91 days 8 97.0 U/l 2.19 6.19 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42762 401
FHH-Chr 2BN/Mcwi serum sodium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount female 77 days-91 days 8 140.63 mmol/l 0.92 2.62 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39375 401
FHH-Chr 2BN/Mcwi percent change in respiration rate air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 10 147.99 % 11.65 36.84 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54310 381
FHH-Chr 2BN/Mcwi blood neutrophil count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity male 77 days-91 days 8 1.35 x 1000 cells/ul 0.15 0.44 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 43216 401
FHH-Chr 2BN/Mcwi hematocrit air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity female 77 days-91 days 8 52.74 % 1.18 3.33 microhematocrit tube assay with visual assessment 0 Moms and pups used in studies were fed Teklad 59244 526
FHH-Chr 2BN/Mcwi hematocrit air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity male 77 days-91 days 8 56.6 % 1.01 2.84 microhematocrit tube assay with visual assessment 0 Moms and pups used in studies were fed Teklad 59249 526
FHH-Chr 2BN/Mcwi serum phosphate level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount female 77 days-91 days 7 10.9 mg/dl 0.35 0.94 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37581 401
FHH-Chr 2BN/Mcwi calculated pulmonary vascular resistance normalized to body weight air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 9 0.18 mmHg x min x kg x ml-1 0.01 0.02 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 59539 526
FHH-Chr 2BN/Mcwi heart weight to body weight ratio air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49 days-63 days 10 7.62 g/kg 0.31 0.97 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45594 461
FHH-Chr 2BN/Mcwi body temperature air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82 days-99 days 10 37.76 degrees C 0.16 0.5 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 16559 381
FHH-Chr 2BN/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait female 77 days-91 days 8 2.88 mg/kg 0.7 1.97 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 58893 526
FHH-Chr 2BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 2.59 ml/min/g 0.2 0.56 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44710 461
FHH-Chr 2BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 10.4 ml/min/g 0.69 1.94 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46645 461
FHH-Chr 2BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 7 22.6 mmHg 5.69 15.05 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45262 461
FHH-Chr 2BN/Mcwi body temperature air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82 days-99 days 10 37.39 degrees C 0.15 0.48 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 16564 381
FHH-Chr 2BN/Mcwi serum glucose level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount male 77 days-91 days 8 154.75 mg/dl 2.94 8.31 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38522 401
FHH-Chr 2BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49 days-63 days 8 10.59 % 3.35 9.48 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49685 461
FHH-Chr 2BN/Mcwi serum total bilirubin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount male 77 days-91 days 8 0.13 mg/dl 0.02 0.05 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 41860 401
FHH-Chr 2BN/Mcwi mean corpuscular volume air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait male 77 days-91 days 8 56.98 fl 0.36 1.02 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38737 401
FHH-Chr 2BN/Mcwi serum calcium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount female 77 days-91 days 8 9.21 mg/dl 0.17 0.47 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36611 401
FHH-Chr 2BN/Mcwi serum chloride level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount male 77 days-91 days 8 109.0 mmol/l 1.1 3.12 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39109 401
FHH-Chr 2BN/Mcwi serum albumin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount male 77 days-91 days 8 3.63 g/dl 0.06 0.17 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42225 401
FHH-Chr 2BN/Mcwi blood eosinophil count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity female 77 days-91 days 8 0.14 x 1000 cells/ul 0.04 0.12 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41634 401
FHH-Chr 2BN/Mcwi methylene blue to FAPGG metabolism-surface area product ratio air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 0.48 null 0.04 0.11 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58100 526
FHH-Chr 2BN/Mcwi methylene blue to FAPGG metabolism-surface area product ratio air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 7 0.43 null 0.03 0.09 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58105 526
FHH-Chr 2BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 7 56.31 mmHg 6.03 15.96 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46409 461
FHH-Chr 2BN/Mcwi percent change in heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 7 post-ischemic value/pre-ischemic value x 100% 77.63 % 6.4 16.94 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48282 461
FHH-Chr 2BN/Mcwi percent change in respiration rate air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 120.14 % 7.05 22.29 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53743 381
FHH-Chr 2BN/Mcwi absolute change in body temperature air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82 days-99 days 10 0.13 degrees C 0.12 0.37 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 20301 381
FHH-Chr 2BN/Mcwi blood neutrophil count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity female 77 days-91 days 8 1.01 x 1000 cells/ul 0.31 0.88 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 43211 401
FHH-Chr 2BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 131.27 mmHg 9.31 26.33 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48616 461
FHH-Chr 2BN/Mcwi mean corpuscular volume air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait female 77 days-91 days 8 58.76 fl 0.32 0.92 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38732 401
FHH-Chr 2BN/Mcwi heart wet weight air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49 days-63 days 10 0.79 g 0.05 0.16 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45392 461
FHH-Chr 2BN/Mcwi percent change in tidal volume air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 99.18 % 5.77 18.25 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53869 381
FHH-Chr 2BN/Mcwi percent change in tidal volume air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 96.04 % 4.33 13.69 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53970 381
FHH-Chr 2BN/Mcwi serum alkaline phosphatase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount female 77 days-91 days 8 262.0 U/l 8.87 25.1 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36366 401
FHH-Chr 2BN/Mcwi minute ventilation air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 43.49 ml/min 2.84 8.99 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18654 381
FHH-Chr 2BN/Mcwi percent change in arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 33.83 % 4.05 12.15 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47064 461
FHH-Chr 2BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 0.25 IU/g 0.04 0.12 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47426 461
FHH-Chr 2BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 119.64 mmHg 8.17 24.5 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45716 461
FHH-Chr 2BN/Mcwi time to onset of heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 8 950.88 s 32.21 91.11 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49291 461
FHH-Chr 2BN/Mcwi plasma creatinine level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount female 77 days-91 days 8 0.36 mg/dl 0.03 0.09 automated plasma creatinine analysis 0 Moms and pups used in studies were fed Teklad 39563 401
FHH-Chr 2BN/Mcwi serum total bilirubin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount female 77 days-91 days 8 0.18 mg/dl 0.02 0.05 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 41855 401
FHH-Chr 2BN/Mcwi serum globulin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount male 77 days-91 days 8 1.65 g/dl 0.12 0.33 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40542 401
FHH-Chr 2BN/Mcwi serum potassium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount female 77 days-91 days 8 4.71 mmol/l 0.17 0.48 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38053 401
FHH-Chr 2BN/Mcwi tidal volume air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 0.24 ml 0.02 0.07 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 15225 381
FHH-Chr 2BN/Mcwi tidal volume air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 0.24 ml 0.02 0.05 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13915 381
FHH-Chr 2BN/Mcwi serum calcium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount male 77 days-91 days 8 9.21 mg/dl 0.07 0.19 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36616 401
FHH-Chr 2BN/Mcwi time to onset of heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 10 997.6 s 39.86 126.04 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49286 461
FHH-Chr 2BN/Mcwi body weight air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass male 49 days-63 days 9 114.8 g 6.4 19.3 whole body digital scale 0 Moms and pups used in studies were fed Teklad 49512 461
FHH-Chr 2BN/Mcwi body weight air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass female 77 days-91 days 10 128.9 g 4.2 13.3 whole body digital scale 0 Moms and pups used in studies were fed Teklad 59049 526
FHH-Chr 2BN/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait male 77 days-91 days 9 2.57 mg/kg 0.74 2.22 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 58898 526
FHH-Chr 2BN/Mcwi lung dry weight to body weight ratio air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass male 77 days-91 days 10 1.56 g/kg 0.04 0.13 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 59649 526
FHH-Chr 2BN/Mcwi blood hemoglobin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 8 16.8 g/dl 0.35 0.99 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 37955 401
FHH-Chr 2BN/Mcwi percent change in left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 20.8 % 3.0 7.36 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48514 461
FHH-Chr 2BN/Mcwi FAPGG metabolism-surface area product air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 7 43.98 ml/min/kg 2.01 5.31 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57991 526
FHH-Chr 2BN/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait male 77 days-91 days 9 0.04 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 58481 526
FHH-Chr 2BN/Mcwi heart right ventricle weight to left ventricle weight ratio air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass male 77 days-91 days 10 0.55 null 0.04 0.12 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 58725 526
FHH-Chr 2BN/Mcwi respiration rate air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 156.24 breaths/min 8.84 27.96 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 14786 381
FHH-Chr 2BN/Mcwi plasma creatinine level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount male 77 days-91 days 8 0.33 mg/dl 0.03 0.07 automated plasma creatinine analysis 0 Moms and pups used in studies were fed Teklad 39568 401
FHH-Chr 2BN/Mcwi mean corpuscular hemoglobin concentration air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 8 32.25 g/dl 0.15 0.41 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39769 401
FHH-Chr 2BN/Mcwi serum alanine aminotransferase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount female 77 days-91 days 8 36.25 U/l 2.4 6.8 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40701 401
FHH-Chr 2BN/Mcwi serum urea nitrogen level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount female 77 days-91 days 8 21.0 mg/dl 1.05 2.98 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40815 401
FHH-Chr 2BN/Mcwi blood eosinophil count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity male 77 days-91 days 8 0.05 x 1000 cells/ul 0.01 0.04 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41639 401
FHH-Chr 2BN/Mcwi methylene blue metabolism-surface area product after auto-oxidation air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 13.68 ml/min/kg 0.91 2.74 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57585 526
FHH-Chr 2BN/Mcwi methylene blue metabolism-surface area product without auto-oxidation air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 9 19.42 ml/min/kg 1.04 3.13 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57792 526
FHH-Chr 2BN/Mcwi percent change in left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 7 post-ischemic value/pre-ischemic value x 100% 59.59 % 6.15 16.26 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48748 461
FHH-Chr 2BN/Mcwi percent change in tidal volume air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 96.69 % 7.51 23.73 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53976 381
FHH-Chr 2BN/Mcwi tidal volume air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 0.23 ml 0.02 0.05 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 15220 381
FHH-Chr 2BN/Mcwi percent change in ventilation air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 %change=VE during 2-3 min hypoxia/control during standard conditions 145.18 % 11.18 35.36 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13667 381
FHH-Chr 2BN/Mcwi serum total cholesterol level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount female 77 days-91 days 8 59.63 mg/dl 2.93 8.3 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37084 401
FHH-Chr 2BN/Mcwi percent change in heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 7 post-ischemic value/pre-ischemic value x 100% 78.07 % 8.12 21.49 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48287 461
FHH-Chr 2BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 53.91 mmHg 4.94 13.96 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46404 461
FHH-Chr 2BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 23.41 mmHg 3.91 11.07 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45257 461
FHH-Chr 2BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 7.1 IU/g 0.77 2.19 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45963 461
FHH-Chr 2BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 7 78.91 mmHg 9.3 24.6 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49880 461
FHH-Chr 2BN/Mcwi serum globulin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount female 77 days-91 days 8 1.5 g/dl 0.07 0.2 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40537 401
FHH-Chr 2BN/Mcwi methylene blue metabolism-surface area product after auto-oxidation air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 9 11.56 ml/min/kg 0.76 2.29 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57590 526
FHH-Chr 2BN/Mcwi respiration rate air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 10 156.15 breaths/min 9.77 30.91 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 14781 381
FHH-Chr 2BN/Mcwi respiration rate air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 10 171.76 breaths/min 14.25 45.06 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18252 381
FHH-Chr 2BN/Mcwi minute ventilation air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 36.05 ml/min 3.83 12.11 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 20195 381
FHH-Chr 2BN/Mcwi absolute change in body temperature air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82 days-99 days 10 0.29 degrees C 0.12 0.37 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 20296 381
FHH-Chr 2BN/Mcwi mean corpuscular hemoglobin air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 8 18.36 pg 0.08 0.21 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 42537 401
FHH-Chr 2BN/Mcwi serum sodium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount male 77 days-91 days 8 141.75 mmol/l 0.84 2.38 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39380 401
FHH-Chr 2BN/Mcwi blood monocyte count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity female 77 days-91 days 8 0.3 x 1000 cells/ul 0.08 0.21 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39661 401
FHH-Chr 2BN/Mcwi blood hemoglobin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 8 18.27 g/dl 0.34 0.98 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 37960 401
FHH-Chr 2BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 9 3.16 ml/min/g 0.52 1.55 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44705 461
FHH-Chr 2BN/Mcwi heart contraction pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 8 29.38 mmHg 2.53 7.15 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49989 461
FHH-Chr 2BN/Mcwi time to peak heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 8 1161.88 s 40.68 115.05 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50219 461
FHH-Chr 2BN/Mcwi serum bicarbonate level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount female 77 days-91 days 8 16.75 mmol/l 0.65 1.83 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42049 401
FHH-Chr 2BN/Mcwi serum bicarbonate level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount male 77 days-91 days 8 16.25 mmol/l 0.56 1.58 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42054 401
FHH-Chr 2BN/Mcwi blood lymphocyte count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity male 77 days-91 days 8 5.18 x 1000 cells/ul 0.62 1.75 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41495 401
FHH-Chr 2BN/Mcwi methylene blue metabolism-surface area product without auto-oxidation air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 25.83 ml/min/kg 1.16 3.47 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57787 526
FHH-Chr 2BN/Mcwi percent change in left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 7 post-ischemic value/pre-ischemic value x 100% 62.73 % 3.46 9.15 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48743 461
FHH-Chr 2BN/Mcwi percent change in arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 25.13 % 1.46 4.14 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47069 461
FHH-Chr 2BN/Mcwi serum alkaline phosphatase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount male 77 days-91 days 8 360.63 U/l 8.02 22.67 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36371 401
FHH-Chr 2BN/Mcwi serum total protein level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount female 77 days-91 days 8 4.86 g/dl 0.08 0.21 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36949 401
FHH-Chr 2BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 7.47 IU/g 1.32 3.96 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45953 461
FHH-Chr 2BN/Mcwi mean corpuscular hemoglobin concentration air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 8 31.89 g/dl 0.15 0.41 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39764 401
FHH-Chr 2BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49 days-63 days 7 9.12 % 1.74 4.61 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49690 461
FHH-Chr 2BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 9 200.32 beats/min 12.22 36.65 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47569 461
FHH-Chr 2BN/Mcwi percent change in respiration rate air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 10 134.9 % 8.26 26.11 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53737 381
FHH-Chr 2BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 112.43 mmHg 9.17 25.93 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48611 461
FHH-Chr 2BN/Mcwi heart right ventricle weight to left ventricle weight ratio air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass female 77 days-91 days 10 0.56 null 0.04 0.13 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 58720 526
FHH-Chr 2BN/Mcwi red blood cell count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77 days-91 days 8 8.98 x 10E6 cells/ul 0.18 0.51 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39224 401
FHH-Chr 2BN/Mcwi calculated pulmonary vascular resistance normalized to body weight air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 0.17 mmHg x min x kg x ml-1 0.01 0.02 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 59534 526
FHH-Chr 2BN/Mcwi percent change in ventilation air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 %change=VE during 2-3 min hypoxia/control during standard conditions 137.56 % 8.88 28.09 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13672 381
FHH-Chr 2BN/Mcwi serum aspartate aminotransferase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount female 77 days-91 days 8 79.25 U/l 3.31 9.36 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42757 401
FHH-Chr 2BN/Mcwi red blood cell count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77 days-91 days 8 9.95 x 10E6 cells/ul 0.15 0.44 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39229 401
FHH-Chr 2BN/Mcwi percent change in respiration rate air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 140.15 % 9.57 30.26 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54316 381
FHH-Chr 2BN/Mcwi blood monocyte count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity male 77 days-91 days 8 0.29 x 1000 cells/ul 0.07 0.19 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39666 401
FHH-Chr 2BN/Mcwi serum phosphate level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount male 77 days-91 days 8 9.45 mg/dl 0.27 0.77 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37586 401
FHH-Chr 2BN/Mcwi serum alanine aminotransferase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount male 77 days-91 days 8 46.63 U/l 1.38 3.89 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40706 401
FHH-Chr 2BN/Mcwi serum urea nitrogen level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount male 77 days-91 days 8 27.88 mg/dl 1.33 3.76 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40820 401
FHH-Chr 2BN/Mcwi total white blood cell count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity female 77 days-91 days 8 7.41 x 1000 cells/ul 1.54 4.35 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 40913 401
FHH-Chr 2BN/Mcwi total white blood cell count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity male 77 days-91 days 8 6.86 x 1000 cells/ul 0.76 2.16 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 40918 401
FHH-Chr 2BN/Mcwi plasma anion gap air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait male 77 days-91 days 8 22.5 mmol/l 0.57 1.6 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38253 401
FHH-Chr 2BN/Mcwi heart weight to body weight ratio air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49 days-63 days 9 7.61 g/kg 0.35 1.04 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45610 461
FHH-Chr 2BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 5.52 mmHg 0.46 1.39 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47184 461
FHH-Chr 2BN/Mcwi hematocrit air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77 days-91 days 8 52.74 % 1.18 3.33 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38978 401
FHH-Chr 2BN/Mcwi body weight air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass male 77 days-91 days 10 157.3 g 3.9 12.4 whole body digital scale 0 Moms and pups used in studies were fed Teklad 59054 526
FHH-Chr 2BN/Mcwi lung dry weight to body weight ratio air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass female 77 days-91 days 10 1.87 g/kg 0.02 0.08 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 59644 526
FHH-Chr 2BN/Mcwi serum potassium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount male 77 days-91 days 7 5.1 mmol/l 0.17 0.46 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38058 401
FHH-Chr 2BN/Mcwi heart wet weight air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49 days-63 days 9 0.87 g 0.07 0.2 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45397 461
FHH-Chr 2BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 8 212.35 beats/min 14.27 40.37 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47574 461
FHH-Chr 2BN/Mcwi FAPGG metabolism-surface area product air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 56.16 ml/min/kg 4.14 12.42 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57986 526
FHH-Chr 2BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 136.34 mmHg 8.96 25.34 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45721 461
FHH-Chr 2BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 10 9.42 ml/min/g 0.6 1.89 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46640 461
FHH-Chr 2BN/Mcwi percent change in tidal volume air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 100.7 % 8.57 27.11 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53875 381
FHH-Chr 2BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 7 155.46 beats/min 14.13 37.38 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45135 461
FHH-Chr 2BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 7 158.11 beats/min 12.95 34.27 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45140 461
FHH-Chr 2BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 77.32 mmHg 3.65 10.32 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49875 461
FHH-Chr 2BN/Mcwi body weight air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass female 49 days-63 days 10 103.6 g 4.3 13.5 whole body digital scale 0 Moms and pups used in studies were fed Teklad 49496 461
FHH-Chr 2BN/Mcwi heart contraction pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 10 25.6 mmHg 1.97 6.24 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49984 461
FHH-Chr 2BN/Mcwi percent change in left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 7 post-ischemic value/pre-ischemic value x 100% 17.32 % 4.06 10.74 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48519 461
FHH-Chr 2BN/Mcwi mean corpuscular hemoglobin air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 8 18.73 pg 0.06 0.16 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 42532 401