Phenominer Database Results (168 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Experiment Notes Record ID Study ID
FHH-Chr 17BN/Mcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 9 120.14 breaths/min 7.52 22.55 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 14843 381
FHH-Chr 17BN/Mcwi partial pressure of blood carbon dioxide (Pco2) controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood gas amount male 82 days-99 days 8 28.59 mmHg 1.08 3.04 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 17231 381
FHH-Chr 17BN/Mcwi partial pressure of blood carbon dioxide (Pco2) controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood gas amount female 82 days-99 days 8 29.95 mmHg 0.79 2.25 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 17235 381
FHH-Chr 17BN/Mcwi absolute change in blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait female 82 days-99 days 8 0.04 null 0.01 0.02 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 19778 381
FHH-Chr 17BN/Mcwi serum alkaline phosphatase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount female 77 days-91 days 6 273.5 U/l 9.04 22.15 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36427 401
FHH-Chr 17BN/Mcwi absolute change in partial pressure of blood carbon dioxide controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood carbon dioxide amount female 82 days-99 days 8 -7.35 mmHg 0.79 2.23 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 19627 381
FHH-Chr 17BN/Mcwi partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount female 82 days-99 days 8 53.36 mmHg 2.14 6.06 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 20469 381
FHH-Chr 17BN/Mcwi red blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77 days-91 days 6 9.4 x 10E6 cells/ul 0.1 0.25 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39283 401
FHH-Chr 17BN/Mcwi plasma creatinine level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount male 77 days-91 days 6 0.3 mg/dl 0.03 0.06 automated plasma creatinine analysis 0 Moms and pups used in studies were fed Teklad 39622 401
FHH-Chr 17BN/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait male 77 days-91 days 9 1.36 mg/kg 0.27 0.8 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 58952 526
FHH-Chr 17BN/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait female 77 days-91 days 8 1.32 mg/kg 0.36 1.03 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 58954 526
FHH-Chr 17BN/Mcwi serum phosphate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount female 77 days-91 days 6 8.5 mg/dl 0.48 1.17 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37642 401
FHH-Chr 17BN/Mcwi lung dry weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass female 77 days-91 days 10 1.83 g/kg 0.04 0.12 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 59705 526
FHH-Chr 17BN/Mcwi serum total bilirubin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount female 77 days-91 days 6 0.1 mg/dl 0.0 0.0 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 41916 401
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 19 236.15 beats/min 6.55 28.55 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47630 461
FHH-Chr 17BN/Mcwi methylene blue metabolism-surface area product without auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 10 27.54 ml/min/kg 1.48 4.67 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57848 526
FHH-Chr 17BN/Mcwi FAPGG metabolism-surface area product controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 10 53.94 ml/min/kg 4.37 13.8 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58047 526
FHH-Chr 17BN/Mcwi heart weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49 days-63 days 20 6.9 g/kg 0.31 1.39 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45619 461
FHH-Chr 17BN/Mcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 16 post-ischemic value/pre-ischemic value x 100% 52.79 % 4.3 17.2 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47125 461
FHH-Chr 17BN/Mcwi serum total cholesterol level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount female 77 days-91 days 6 64.33 mg/dl 1.89 4.63 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37145 401
FHH-Chr 17BN/Mcwi serum calcium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount female 77 days-91 days 6 9.68 mg/dl 0.15 0.38 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36672 401
FHH-Chr 17BN/Mcwi absolute change in blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait male 82 days-99 days 8 0.04 null 0.01 0.03 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 19774 381
FHH-Chr 17BN/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 17 5.44 ml/min/g 0.38 1.56 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44764 461
FHH-Chr 17BN/Mcwi blood eosinophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity female 77 days-91 days 6 0.03 x 1000 cells/ul 0.01 0.02 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41695 401
FHH-Chr 17BN/Mcwi plasma creatinine level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount female 77 days-91 days 6 0.25 mg/dl 0.02 0.05 automated plasma creatinine analysis 0 Moms and pups used in studies were fed Teklad 39624 401
FHH-Chr 17BN/Mcwi blood lymphocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity female 77 days-91 days 6 4.14 x 1000 cells/ul 0.49 1.21 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41551 401
FHH-Chr 17BN/Mcwi blood neutrophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity male 77 days-91 days 6 0.67 x 1000 cells/ul 0.08 0.19 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 43270 401
FHH-Chr 17BN/Mcwi blood neutrophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity female 77 days-91 days 6 0.45 x 1000 cells/ul 0.12 0.3 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 43272 401
FHH-Chr 17BN/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass male 77 days-91 days 10 181.0 g 4.5 14.1 whole body digital scale 0 Moms and pups used in studies were fed Teklad 59108 526
FHH-Chr 17BN/Mcwi heart right ventricle weight to left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass female 77 days-91 days 10 0.49 null 0.03 0.1 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 58781 526
FHH-Chr 17BN/Mcwi mean corpuscular volume controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait female 77 days-91 days 6 58.58 fl 0.07 0.17 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38793 401
FHH-Chr 17BN/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 10 117.37 mmHg 4.73 14.95 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48670 461
FHH-Chr 17BN/Mcwi calculated pulmonary vascular resistance normalized to body weight controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 10 0.16 mmHg x min x kg x ml-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 59595 526
FHH-Chr 17BN/Mcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 11 0.31 ml 0.03 0.08 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13970 381
FHH-Chr 17BN/Mcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 11 110.4 breaths/min 4.15 13.75 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 14841 381
FHH-Chr 17BN/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 11 109.96 % 5.04 16.71 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53799 381
FHH-Chr 17BN/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 11 118.27 % 9.17 30.4 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53931 381
FHH-Chr 17BN/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 102.65 % 2.59 7.77 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53933 381
FHH-Chr 17BN/Mcwi serum alkaline phosphatase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount male 77 days-91 days 6 397.0 U/l 34.66 84.9 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36425 401
FHH-Chr 17BN/Mcwi absolute change in partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount female 82 days-99 days 8 -41.44 mmHg 2.97 8.41 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 19457 381
FHH-Chr 17BN/Mcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 17 1179.29 s 30.51 125.79 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50273 461
FHH-Chr 17BN/Mcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 19 1179.79 s 46.27 201.67 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50275 461
FHH-Chr 17BN/Mcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 17 39.0 mmHg 2.99 12.32 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50043 461
FHH-Chr 17BN/Mcwi red blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77 days-91 days 6 8.46 x 10E6 cells/ul 0.23 0.57 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39285 401
FHH-Chr 17BN/Mcwi mean corpuscular hemoglobin concentration controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 6 31.95 g/dl 0.12 0.29 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39823 401
FHH-Chr 17BN/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 9 122.68 % 7.55 22.64 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54374 381
FHH-Chr 17BN/Mcwi blood monocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity female 77 days-91 days 6 0.22 x 1000 cells/ul 0.04 0.09 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39722 401
FHH-Chr 17BN/Mcwi plasma anion gap controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait female 77 days-91 days 6 16.83 mmol/l 1.51 3.71 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38309 401
FHH-Chr 17BN/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 15 48.56 mmHg 3.7 14.33 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46465 461
FHH-Chr 17BN/Mcwi serum glucose level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount female 77 days-91 days 6 120.67 mg/dl 7.45 18.25 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38578 401
FHH-Chr 17BN/Mcwi methylene blue metabolism-surface area product after auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 10 17.33 ml/min/kg 0.48 1.51 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57644 526
FHH-Chr 17BN/Mcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82 days-99 days 10 36.67 degrees C 0.3 0.95 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 16621 381
FHH-Chr 17BN/Mcwi methylene blue to FAPGG metabolism-surface area product ratio controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 10 0.53 null 0.03 0.09 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58161 526
FHH-Chr 17BN/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait female 77 days-91 days 10 0.03 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 58537 526
FHH-Chr 17BN/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 17 10.3 ml/min/g 0.29 1.21 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46699 461
FHH-Chr 17BN/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 19 10.42 ml/min/g 0.33 1.45 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46701 461
FHH-Chr 17BN/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 17 43.84 mmHg 6.58 27.13 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45316 461
FHH-Chr 17BN/Mcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82 days-99 days 11 0.16 degrees C 0.25 0.84 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 20356 381
FHH-Chr 17BN/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 93.31 % 2.73 8.18 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54034 381
FHH-Chr 17BN/Mcwi absolute change in partial pressure of blood carbon dioxide controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood carbon dioxide amount male 82 days-99 days 8 -5.05 mmHg 0.92 2.6 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 19623 381
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 17 215.43 beats/min 14.01 57.77 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45194 461
FHH-Chr 17BN/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass female 49 days-63 days 20 148.1 g 2.4 10.7 whole body digital scale 0 Moms and pups used in studies were fed Teklad 49521 461
FHH-Chr 17BN/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 16 93.31 mmHg 8.42 33.67 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49936 461
FHH-Chr 17BN/Mcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 14 post-ischemic value/pre-ischemic value x 100% 96.21 % 12.87 48.17 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48804 461
FHH-Chr 17BN/Mcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 11 %change=VE during 2-3 min hypoxia/control during standard conditions 148.7 % 11.84 39.27 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13727 381
FHH-Chr 17BN/Mcwi serum total protein level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount male 77 days-91 days 6 5.23 g/dl 0.04 0.1 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37008 401
FHH-Chr 17BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 9 136.03 mmHg 9.09 27.28 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 14320 381
FHH-Chr 17BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 8 128.35 mmHg 6.12 17.31 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 14324 381
FHH-Chr 17BN/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 11 38.7 ml/min 3.2 10.6 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18709 381
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82 days-99 days 8 418.05 beats/min 9.42 26.66 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 17497 381
FHH-Chr 17BN/Mcwi partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount male 82 days-99 days 8 52.75 mmHg 2.36 6.68 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 20465 381
FHH-Chr 17BN/Mcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82 days-99 days 10 0.09 degrees C 0.24 0.77 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 20358 381
FHH-Chr 17BN/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 11 126.2 % 3.86 12.8 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54372 381
FHH-Chr 17BN/Mcwi serum phosphate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount male 77 days-91 days 6 8.87 mg/dl 0.19 0.47 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37640 401
FHH-Chr 17BN/Mcwi blood hemoglobin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 6 17.35 g/dl 0.15 0.36 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38014 401
FHH-Chr 17BN/Mcwi blood lymphocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity male 77 days-91 days 6 5.02 x 1000 cells/ul 0.38 0.93 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41549 401
FHH-Chr 17BN/Mcwi heart wet weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49 days-63 days 20 1.15 g 0.07 0.3 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45451 461
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 17 243.5 beats/min 4.85 20.01 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47628 461
FHH-Chr 17BN/Mcwi methylene blue metabolism-surface area product without auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 10 25.45 ml/min/kg 1.09 3.45 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57846 526
FHH-Chr 17BN/Mcwi FAPGG metabolism-surface area product controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 10 61.09 ml/min/kg 4.69 14.84 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58045 526
FHH-Chr 17BN/Mcwi heart right ventricle weight to left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass male 77 days-91 days 10 0.54 null 0.04 0.13 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 58779 526
FHH-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 17 20.0 IU/g 2.15 8.86 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45970 461
FHH-Chr 17BN/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 13 126.83 mmHg 4.56 16.44 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45777 461
FHH-Chr 17BN/Mcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 17 post-ischemic value/pre-ischemic value x 100% 53.38 % 3.75 15.47 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47123 461
FHH-Chr 17BN/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 18 5.14 mmHg 0.24 1.02 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47245 461
FHH-Chr 17BN/Mcwi serum calcium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount male 77 days-91 days 6 9.93 mg/dl 0.11 0.26 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36670 401
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 16 216.36 beats/min 35.27 141.07 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45196 461
FHH-Chr 17BN/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 16 5.36 ml/min/g 0.38 1.54 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44766 461
FHH-Chr 17BN/Mcwi serum aspartate aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount female 77 days-91 days 6 100.0 U/l 5.85 14.32 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42818 401
FHH-Chr 17BN/Mcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 19 945.84 s 44.39 193.51 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49347 461
FHH-Chr 17BN/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 17 92.9 mmHg 7.5 30.93 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49934 461
FHH-Chr 17BN/Mcwi serum alanine aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount female 77 days-91 days 6 49.17 U/l 4.32 10.57 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40762 401
FHH-Chr 17BN/Mcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 16 post-ischemic value/pre-ischemic value x 100% 93.7 % 8.26 33.02 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48802 461
FHH-Chr 17BN/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity female 77 days-91 days 6 49.57 % 1.33 3.26 microhematocrit tube assay with visual assessment 0 Moms and pups used in studies were fed Teklad 59305 526
FHH-Chr 17BN/Mcwi serum albumin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount male 77 days-91 days 6 3.92 g/dl 0.03 0.08 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42279 401
FHH-Chr 17BN/Mcwi serum sodium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount male 77 days-91 days 6 145.0 mmol/l 0.52 1.26 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39434 401
FHH-Chr 17BN/Mcwi serum sodium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount female 77 days-91 days 6 144.5 mmol/l 0.56 1.38 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39436 401
FHH-Chr 17BN/Mcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 11 0.28 ml 0.02 0.06 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 15280 381
FHH-Chr 17BN/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 9 117.43 % 6.05 18.16 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53801 381
FHH-Chr 17BN/Mcwi absolute change in partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount male 82 days-99 days 8 -42.29 mmHg 2.8 7.93 automated blood gas analysis using a Bayer analyzer 0 Moms and pups used in studies were fed Teklad 19453 381
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82 days-99 days 9 425.96 beats/min 24.66 73.99 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 17493 381
FHH-Chr 17BN/Mcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 19 39.26 mmHg 2.44 10.65 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50045 461
FHH-Chr 17BN/Mcwi mean corpuscular volume controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait male 77 days-91 days 6 57.8 fl 0.33 0.81 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38791 401
FHH-Chr 17BN/Mcwi serum albumin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount female 77 days-91 days 6 3.8 g/dl 0.04 0.11 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42281 401
FHH-Chr 17BN/Mcwi serum chloride level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount male 77 days-91 days 6 110.67 mmol/l 0.49 1.21 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39163 401
FHH-Chr 17BN/Mcwi serum chloride level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount female 77 days-91 days 6 110.17 mmol/l 0.79 1.94 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39165 401
FHH-Chr 17BN/Mcwi serum aspartate aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount male 77 days-91 days 6 111.0 U/l 9.75 23.87 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42816 401
FHH-Chr 17BN/Mcwi mean corpuscular hemoglobin controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 6 18.47 pg 0.11 0.28 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 42591 401
FHH-Chr 17BN/Mcwi mean corpuscular hemoglobin concentration controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 6 32.03 g/dl 0.16 0.39 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39825 401
FHH-Chr 17BN/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity male 77 days-91 days 6 54.32 % 0.44 1.07 microhematocrit tube assay with visual assessment 0 Moms and pups used in studies were fed Teklad 59303 526
FHH-Chr 17BN/Mcwi serum alanine aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount male 77 days-91 days 6 66.67 U/l 7.21 17.66 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40760 401
FHH-Chr 17BN/Mcwi total white blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity male 77 days-91 days 6 6.15 x 1000 cells/ul 0.36 0.88 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 40972 401
FHH-Chr 17BN/Mcwi blood hemoglobin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 6 15.87 g/dl 0.38 0.94 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38016 401
FHH-Chr 17BN/Mcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount male 77 days-91 days 6 4.8 mmol/l 0.14 0.35 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38112 401
FHH-Chr 17BN/Mcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount female 77 days-91 days 6 4.5 mmol/l 0.36 0.88 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38114 401
FHH-Chr 17BN/Mcwi heart wet weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49 days-63 days 20 1.02 g 0.05 0.23 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45453 461
FHH-Chr 17BN/Mcwi serum total bilirubin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount male 77 days-91 days 6 0.08 mg/dl 0.01 0.03 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 41914 401
FHH-Chr 17BN/Mcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 11 post-ischemic value/pre-ischemic value x 100% 43.73 % 7.11 23.57 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48575 461
FHH-Chr 17BN/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 16 52.93 mmHg 5.07 20.28 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46463 461
FHH-Chr 17BN/Mcwi methylene blue to FAPGG metabolism-surface area product ratio controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 10 0.43 null 0.03 0.09 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58159 526
FHH-Chr 17BN/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait male 77 days-91 days 10 0.03 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 58535 526
FHH-Chr 17BN/Mcwi heart weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49 days-63 days 20 6.79 g/kg 0.43 1.91 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45616 461
FHH-Chr 17BN/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 10 122.08 mmHg 4.5 14.23 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45775 461
FHH-Chr 17BN/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 15 5.29 mmHg 0.22 0.84 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47243 461
FHH-Chr 17BN/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 16 48.52 mmHg 6.4 25.6 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45318 461
FHH-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 19 0.27 IU/g 0.02 0.11 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47450 461
FHH-Chr 17BN/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 11 31.25 ml/min 2.29 7.6 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 20255 381
FHH-Chr 17BN/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 28.14 ml/min 2.76 8.29 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 20257 381
FHH-Chr 17BN/Mcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 9 124.69 breaths/min 6.84 20.53 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18314 381
FHH-Chr 17BN/Mcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 17 post-ischemic value/pre-ischemic value x 100% 87.67 % 4.63 19.1 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48341 461
FHH-Chr 17BN/Mcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 16 post-ischemic value/pre-ischemic value x 100% 93.49 % 15.85 63.4 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48343 461
FHH-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 17 19.74 IU/g 2.1 8.67 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45967 461
FHH-Chr 17BN/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass female 77 days-91 days 10 155.2 g 2.5 7.9 whole body digital scale 0 Moms and pups used in studies were fed Teklad 59110 526
FHH-Chr 17BN/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 13 121.83 mmHg 4.63 16.69 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48672 461
FHH-Chr 17BN/Mcwi calculated pulmonary vascular resistance normalized to body weight controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 10 0.16 mmHg x min x kg x ml-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 59593 526
FHH-Chr 17BN/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77 days-91 days 6 54.32 % 0.44 1.07 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39037 401
FHH-Chr 17BN/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 11 109.07 % 5.02 16.65 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54032 381
FHH-Chr 17BN/Mcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 %change=VE during 2-3 min hypoxia/control during standard conditions 125.79 % 8.32 24.97 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13729 381
FHH-Chr 17BN/Mcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 0.26 ml 0.01 0.04 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13972 381
FHH-Chr 17BN/Mcwi serum total cholesterol level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount male 77 days-91 days 6 67.17 mg/dl 1.85 4.54 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37143 401
FHH-Chr 17BN/Mcwi blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait male 82 days-99 days 8 7.49 null 0.01 0.03 automated blood gas analysis using a Bayer analyzer 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17038 381
FHH-Chr 17BN/Mcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 11 127.07 breaths/min 3.95 13.11 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18312 381
FHH-Chr 17BN/Mcwi serum total protein level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount female 77 days-91 days 6 5.05 g/dl 0.06 0.15 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37010 401
FHH-Chr 17BN/Mcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 0.23 ml 0.01 0.04 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 15282 381
FHH-Chr 17BN/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 32.09 ml/min 2.73 8.2 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18711 381
FHH-Chr 17BN/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass male 49 days-63 days 20 169.7 g 3.6 16.3 whole body digital scale 0 Moms and pups used in studies were fed Teklad 49518 461
FHH-Chr 17BN/Mcwi serum bicarbonate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount male 77 days-91 days 6 21.67 mmol/l 1.63 3.98 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42108 401
FHH-Chr 17BN/Mcwi mean corpuscular hemoglobin controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 6 18.73 pg 0.09 0.22 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 42593 401
FHH-Chr 17BN/Mcwi serum globulin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount female 77 days-91 days 6 1.25 g/dl 0.04 0.1 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40598 401
FHH-Chr 17BN/Mcwi serum globulin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount male 77 days-91 days 6 1.32 g/dl 0.02 0.04 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40596 401
FHH-Chr 17BN/Mcwi total white blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity female 77 days-91 days 6 4.83 x 1000 cells/ul 0.58 1.43 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 40974 401
FHH-Chr 17BN/Mcwi plasma anion gap controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait male 77 days-91 days 6 17.5 mmol/l 1.69 4.14 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38307 401
FHH-Chr 17BN/Mcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 46.16 % 6.4 20.22 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48573 461
FHH-Chr 17BN/Mcwi methylene blue metabolism-surface area product after auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 10 18.47 ml/min/kg 0.97 3.05 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57646 526
FHH-Chr 17BN/Mcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82 days-99 days 11 36.63 degrees C 0.25 0.82 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 16619 381
FHH-Chr 17BN/Mcwi blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait female 82 days-99 days 8 7.46 null 0.01 0.02 automated blood gas analysis using a Bayer analyzer 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17042 381
FHH-Chr 17BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 17 0.26 IU/g 0.06 0.24 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47447 461
FHH-Chr 17BN/Mcwi blood monocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity male 77 days-91 days 6 0.42 x 1000 cells/ul 0.03 0.08 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39720 401
FHH-Chr 17BN/Mcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 17 941.65 s 25.06 103.35 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49345 461
FHH-Chr 17BN/Mcwi serum glucose level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount male 77 days-91 days 6 136.83 mg/dl 3.79 9.28 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38576 401
FHH-Chr 17BN/Mcwi blood eosinophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity male 77 days-91 days 6 0.04 x 1000 cells/ul 0.03 0.07 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41693 401
FHH-Chr 17BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49 days-63 days 17 12.84 % 2.61 10.76 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49744 461
FHH-Chr 17BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49 days-63 days 17 10.56 % 2.37 9.77 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49746 461
FHH-Chr 17BN/Mcwi serum bicarbonate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount female 77 days-91 days 6 22.17 mmol/l 1.78 4.36 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42110 401
FHH-Chr 17BN/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77 days-91 days 6 49.57 % 1.33 3.26 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39039 401
FHH-Chr 17BN/Mcwi serum urea nitrogen level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount male 77 days-91 days 6 25.17 mg/dl 2.56 6.27 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40874 401
FHH-Chr 17BN/Mcwi serum urea nitrogen level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount female 77 days-91 days 6 24.5 mg/dl 0.72 1.76 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40876 401
FHH-Chr 17BN/Mcwi lung dry weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass male 77 days-91 days 10 1.61 g/kg 0.03 0.08 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 59703 526