Phenominer Database Results (152 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Experiment Notes Record ID Study ID
FHH-Chr 15BN/Mcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 0.34 ml 0.04 0.12 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13951 381
FHH-Chr 15BN/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 128.03 % 11.54 36.5 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53782 381
FHH-Chr 15BN/Mcwi serum alkaline phosphatase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount female 77 days-91 days 8 348.13 U/l 12.3 34.8 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36418 401
FHH-Chr 15BN/Mcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 0.29 ml 0.02 0.08 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 15261 381
FHH-Chr 15BN/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 37.87 ml/min 2.92 8.76 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 20248 381
FHH-Chr 15BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49 days-63 days 8 10.98 % 3.68 10.42 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49726 461
FHH-Chr 15BN/Mcwi serum bicarbonate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount male 77 days-91 days 8 21.38 mmol/l 1.13 3.2 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42090 401
FHH-Chr 15BN/Mcwi mean corpuscular hemoglobin controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 8 18.63 pg 0.11 0.31 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 42573 401
FHH-Chr 15BN/Mcwi blood neutrophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity male 77 days-91 days 8 1.35 x 1000 cells/ul 0.18 0.51 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 43252 401
FHH-Chr 15BN/Mcwi blood monocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity female 77 days-91 days 8 0.59 x 1000 cells/ul 0.19 0.52 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39713 401
FHH-Chr 15BN/Mcwi mean corpuscular hemoglobin concentration controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 8 32.11 g/dl 0.18 0.52 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39805 401
FHH-Chr 15BN/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait female 77 days-91 days 7 3.81 mg/kg 0.73 1.93 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 58945 526
FHH-Chr 15BN/Mcwi serum phosphate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount male 77 days-91 days 8 10.68 mg/dl 0.35 1.0 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37622 401
FHH-Chr 15BN/Mcwi serum alanine aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount male 77 days-91 days 8 78.5 U/l 5.8 16.41 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40742 401
FHH-Chr 15BN/Mcwi serum alanine aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount female 77 days-91 days 8 75.88 U/l 7.18 20.31 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40753 401
FHH-Chr 15BN/Mcwi plasma anion gap controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait male 77 days-91 days 8 17.5 mmol/l 1.32 3.74 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38289 401
FHH-Chr 15BN/Mcwi blood eosinophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity female 77 days-91 days 8 0.0 x 1000 cells/ul 0.0 0.0 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41686 401
FHH-Chr 15BN/Mcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 27.96 % 7.47 18.3 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48555 461
FHH-Chr 15BN/Mcwi methylene blue metabolism-surface area product after auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 12.21 ml/min/kg 1.1 3.29 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57637 526
FHH-Chr 15BN/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 6 4.99 ml/min/g 1.16 2.84 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44757 461
FHH-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 0.43 IU/g 0.1 0.28 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47440 461
FHH-Chr 15BN/Mcwi serum total protein level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount male 77 days-91 days 8 4.69 g/dl 0.09 0.26 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36990 401
FHH-Chr 15BN/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 5 28.17 mmHg 5.21 11.65 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45309 461
FHH-Chr 15BN/Mcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82 days-99 days 10 37.24 degrees C 0.27 0.86 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 16600 381
FHH-Chr 15BN/Mcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 8 1192.75 s 30.33 85.78 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50255 461
FHH-Chr 15BN/Mcwi heart right ventricle weight to left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass male 77 days-91 days 10 0.54 null 0.02 0.07 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 58761 526
FHH-Chr 15BN/Mcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 %change=VE during 2-3 min hypoxia/control during standard conditions 141.45 % 6.54 20.67 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13708 381
FHH-Chr 15BN/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 113.26 % 6.71 21.21 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53914 381
FHH-Chr 15BN/Mcwi serum calcium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount female 77 days-91 days 8 9.1 mg/dl 0.29 0.81 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36663 401
FHH-Chr 15BN/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 44.14 ml/min 3.08 9.74 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18690 381
FHH-Chr 15BN/Mcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 8 928.88 s 27.06 76.53 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49327 461
FHH-Chr 15BN/Mcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 8 23.88 mmHg 2.21 6.24 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50036 461
FHH-Chr 15BN/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77 days-91 days 8 54.43 % 0.88 2.48 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39019 401
FHH-Chr 15BN/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77 days-91 days 8 54.14 % 1.65 4.65 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39030 401
FHH-Chr 15BN/Mcwi serum albumin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount female 77 days-91 days 8 3.33 g/dl 0.09 0.26 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42272 401
FHH-Chr 15BN/Mcwi mean corpuscular volume controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait male 77 days-91 days 8 58.04 fl 0.53 1.49 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38773 401
FHH-Chr 15BN/Mcwi mean corpuscular volume controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait female 77 days-91 days 8 58.56 fl 0.8 2.27 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38784 401
FHH-Chr 15BN/Mcwi mean corpuscular hemoglobin controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 8 18.76 pg 0.25 0.71 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 42584 401
FHH-Chr 15BN/Mcwi plasma creatinine level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount female 77 days-91 days 8 0.3 mg/dl 0.03 0.08 automated plasma creatinine analysis 0 Moms and pups used in studies were fed Teklad 39615 401
FHH-Chr 15BN/Mcwi total white blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity male 77 days-91 days 8 8.34 x 1000 cells/ul 0.86 2.43 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 40954 401
FHH-Chr 15BN/Mcwi calculated pulmonary vascular resistance normalized to body weight controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 8 0.15 mmHg x min x kg x ml-1 0.01 0.03 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 59575 526
FHH-Chr 15BN/Mcwi serum glucose level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount male 77 days-91 days 8 124.75 mg/dl 5.5 15.56 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38558 401
FHH-Chr 15BN/Mcwi FAPGG metabolism-surface area product controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 8 62.65 ml/min/kg 9.87 27.91 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58027 526
FHH-Chr 15BN/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 105.2 mmHg 9.77 23.94 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45757 461
FHH-Chr 15BN/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 8 9.99 ml/min/g 0.44 1.24 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46692 461
FHH-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 6 13.84 IU/g 1.68 4.1 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45960 461
FHH-Chr 15BN/Mcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 48.53 % 8.18 20.03 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47116 461
FHH-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 0.32 IU/g 0.12 0.33 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47421 461
FHH-Chr 15BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 16.71 IU/g 2.7 7.63 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45950 461
FHH-Chr 15BN/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 44.27 mmHg 3.66 8.97 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46445 461
FHH-Chr 15BN/Mcwi heart wet weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49 days-63 days 9 0.63 g 0.06 0.19 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45433 461
FHH-Chr 15BN/Mcwi heart wet weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49 days-63 days 9 0.75 g 0.06 0.17 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45444 461
FHH-Chr 15BN/Mcwi heart right ventricle weight to left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass female 77 days-91 days 13 0.5 null 0.02 0.08 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 58772 526
FHH-Chr 15BN/Mcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 9 145.72 breaths/min 7.78 23.34 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18305 381
FHH-Chr 15BN/Mcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82 days-99 days 9 0.24 degrees C 0.1 0.3 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 20349 381
FHH-Chr 15BN/Mcwi serum aspartate aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount male 77 days-91 days 8 116.38 U/l 6.75 19.1 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42798 401
FHH-Chr 15BN/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 126.71 % 5.71 18.06 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54355 381
FHH-Chr 15BN/Mcwi blood monocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity male 77 days-91 days 8 0.4 x 1000 cells/ul 0.1 0.28 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39702 401
FHH-Chr 15BN/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass male 77 days-91 days 10 110.6 g 4.8 15.3 whole body digital scale 0 Moms and pups used in studies were fed Teklad 59090 526
FHH-Chr 15BN/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass female 77 days-91 days 13 104.2 g 3.9 14.0 whole body digital scale 0 Moms and pups used in studies were fed Teklad 59101 526
FHH-Chr 15BN/Mcwi plasma creatinine level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount male 77 days-91 days 8 0.25 mg/dl 0.02 0.05 automated plasma creatinine analysis 0 Moms and pups used in studies were fed Teklad 39604 401
FHH-Chr 15BN/Mcwi serum globulin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount female 77 days-91 days 8 1.36 g/dl 0.04 0.12 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40589 401
FHH-Chr 15BN/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity male 77 days-91 days 8 54.43 % 0.88 2.48 microhematocrit tube assay with visual assessment 0 Moms and pups used in studies were fed Teklad 59285 526
FHH-Chr 15BN/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity female 77 days-91 days 8 54.14 % 1.65 4.65 microhematocrit tube assay with visual assessment 0 Moms and pups used in studies were fed Teklad 59296 526
FHH-Chr 15BN/Mcwi lung dry weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass male 77 days-91 days 10 1.64 g/kg 0.05 0.15 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 59685 526
FHH-Chr 15BN/Mcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount male 77 days-91 days 7 5.16 mmol/l 0.31 0.83 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38094 401
FHH-Chr 15BN/Mcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 5 post-ischemic value/pre-ischemic value x 100% 31.21 % 5.65 12.63 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48566 461
FHH-Chr 15BN/Mcwi serum total bilirubin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount female 77 days-91 days 8 0.19 mg/dl 0.02 0.06 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 41907 401
FHH-Chr 15BN/Mcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 70.79 % 12.12 29.68 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48784 461
FHH-Chr 15BN/Mcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 5 post-ischemic value/pre-ischemic value x 100% 69.86 % 3.8 8.49 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48795 461
FHH-Chr 15BN/Mcwi methylene blue metabolism-surface area product after auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 8 13.09 ml/min/kg 1.89 5.35 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57626 526
FHH-Chr 15BN/Mcwi heart weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49 days-63 days 9 8.3 g/kg 0.39 1.18 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45608 461
FHH-Chr 15BN/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 7 5.63 mmHg 0.47 1.25 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47236 461
FHH-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 8 159.95 beats/min 16.39 46.35 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45176 461
FHH-Chr 15BN/Mcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 87.45 % 7.1 17.4 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48334 461
FHH-Chr 15BN/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 45.53 ml/min 3.91 11.72 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18702 381
FHH-Chr 15BN/Mcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 9 127.26 breaths/min 9.39 28.18 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 14834 381
FHH-Chr 15BN/Mcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 73.44 % 8.2 23.21 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48323 461
FHH-Chr 15BN/Mcwi serum aspartate aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount female 77 days-91 days 8 104.63 U/l 7.35 20.78 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42809 401
FHH-Chr 15BN/Mcwi heart weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49 days-63 days 9 6.29 g/kg 0.36 1.08 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45589 461
FHH-Chr 15BN/Mcwi serum globulin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount male 77 days-91 days 8 1.36 g/dl 0.05 0.15 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40578 401
FHH-Chr 15BN/Mcwi blood hemoglobin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 8 17.35 g/dl 0.51 1.45 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38007 401
FHH-Chr 15BN/Mcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 0.3 ml 0.02 0.05 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 15273 381
FHH-Chr 15BN/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 99.58 % 5.2 16.44 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54015 381
FHH-Chr 15BN/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 9 125.44 % 13.37 40.11 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53793 381
FHH-Chr 15BN/Mcwi serum total cholesterol level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount male 77 days-91 days 8 77.5 mg/dl 2.09 5.9 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37125 401
FHH-Chr 15BN/Mcwi serum total cholesterol level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount female 77 days-91 days 8 69.88 mg/dl 2.78 7.86 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37136 401
FHH-Chr 15BN/Mcwi serum calcium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount male 77 days-91 days 8 8.96 mg/dl 0.14 0.4 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36652 401
FHH-Chr 15BN/Mcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 136.23 breaths/min 7.16 22.66 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18293 381
FHH-Chr 15BN/Mcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 8 991.13 s 82.23 232.59 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49338 461
FHH-Chr 15BN/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 5 69.06 mmHg 6.29 14.05 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49927 461
FHH-Chr 15BN/Mcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 8 24.5 mmHg 2.77 7.84 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50025 461
FHH-Chr 15BN/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass male 49 days-63 days 9 100.8 g 8.3 25.0 whole body digital scale 0 Moms and pups used in studies were fed Teklad 49491 461
FHH-Chr 15BN/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass female 49 days-63 days 9 91.1 g 6.5 19.5 whole body digital scale 0 Moms and pups used in studies were fed Teklad 49510 461
FHH-Chr 15BN/Mcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 8 1302.75 s 39.98 113.09 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50266 461
FHH-Chr 15BN/Mcwi serum chloride level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount male 77 days-91 days 8 107.38 mmol/l 0.63 1.77 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39145 401
FHH-Chr 15BN/Mcwi serum albumin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount male 77 days-91 days 8 3.33 g/dl 0.07 0.19 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42261 401
FHH-Chr 15BN/Mcwi red blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77 days-91 days 8 9.38 x 10E6 cells/ul 0.11 0.32 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39265 401
FHH-Chr 15BN/Mcwi red blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77 days-91 days 8 9.25 x 10E6 cells/ul 0.22 0.62 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39276 401
FHH-Chr 15BN/Mcwi serum sodium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount female 77 days-91 days 8 142.13 mmol/l 1.26 3.56 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39427 401
FHH-Chr 15BN/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 9 142.56 % 10.31 30.94 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54366 381
FHH-Chr 15BN/Mcwi blood neutrophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity female 77 days-91 days 8 1.27 x 1000 cells/ul 0.22 0.62 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 43263 401
FHH-Chr 15BN/Mcwi serum phosphate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount female 77 days-91 days 8 11.04 mg/dl 0.51 1.44 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37633 401
FHH-Chr 15BN/Mcwi serum urea nitrogen level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount female 77 days-91 days 8 26.0 mg/dl 1.78 5.04 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40867 401
FHH-Chr 15BN/Mcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount female 77 days-91 days 8 5.11 mmol/l 0.36 1.03 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38105 401
FHH-Chr 15BN/Mcwi blood lymphocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity female 77 days-91 days 8 7.5 x 1000 cells/ul 0.82 2.33 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41542 401
FHH-Chr 15BN/Mcwi serum glucose level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount female 77 days-91 days 8 145.13 mg/dl 11.21 31.69 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38569 401
FHH-Chr 15BN/Mcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82 days-99 days 9 37.18 degrees C 0.19 0.58 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 16612 381
FHH-Chr 15BN/Mcwi methylene blue to FAPGG metabolism-surface area product ratio controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 8 0.41 null 0.06 0.17 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58141 526
FHH-Chr 15BN/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait male 77 days-91 days 9 2.42 mg/kg 0.72 2.17 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 58934 526
FHH-Chr 15BN/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 101.18 % 5.81 17.43 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54026 381
FHH-Chr 15BN/Mcwi serum total protein level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount female 77 days-91 days 8 4.69 g/dl 0.12 0.33 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37001 401
FHH-Chr 15BN/Mcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 %change=VE during 2-3 min hypoxia/control during standard conditions 145.79 % 8.45 25.34 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13720 381
FHH-Chr 15BN/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 4.97 mmHg 0.33 0.8 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47225 461
FHH-Chr 15BN/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 13.47 ml/min/g 1.6 4.52 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46681 461
FHH-Chr 15BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49 days-63 days 7 4.81 % 1.32 3.49 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49737 461
FHH-Chr 15BN/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 7 95.93 mmHg 8.89 23.53 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48663 461
FHH-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 8 223.66 beats/min 14.03 39.68 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47610 461
FHH-Chr 15BN/Mcwi blood hemoglobin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 8 17.49 g/dl 0.25 0.7 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 37996 401
FHH-Chr 15BN/Mcwi FAPGG metabolism-surface area product controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 69.53 ml/min/kg 2.37 7.12 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58038 526
FHH-Chr 15BN/Mcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 137.56 breaths/min 11.98 37.88 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 14822 381
FHH-Chr 15BN/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 103.68 % 3.99 11.97 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53925 381
FHH-Chr 15BN/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 38.87 ml/min 2.95 9.34 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 20236 381
FHH-Chr 15BN/Mcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82 days-99 days 10 0.43 degrees C 0.21 0.67 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 20337 381
FHH-Chr 15BN/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 71.28 mmHg 10.11 24.77 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49916 461
FHH-Chr 15BN/Mcwi serum bicarbonate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount female 77 days-91 days 8 21.5 mmol/l 0.78 2.2 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42101 401
FHH-Chr 15BN/Mcwi serum sodium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount male 77 days-91 days 8 140.63 mmol/l 0.38 1.06 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39416 401
FHH-Chr 15BN/Mcwi mean corpuscular hemoglobin concentration controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 8 32.04 g/dl 0.17 0.48 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39816 401
FHH-Chr 15BN/Mcwi serum urea nitrogen level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount male 77 days-91 days 8 28.88 mg/dl 1.75 4.94 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40856 401
FHH-Chr 15BN/Mcwi total white blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity female 77 days-91 days 8 9.35 x 1000 cells/ul 1.09 3.09 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 40965 401
FHH-Chr 15BN/Mcwi lung dry weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass female 77 days-91 days 13 1.8 g/kg 0.04 0.16 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 59696 526
FHH-Chr 15BN/Mcwi calculated pulmonary vascular resistance normalized to body weight controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 0.16 mmHg x min x kg x ml-1 0.01 0.02 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 59586 526
FHH-Chr 15BN/Mcwi blood lymphocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity male 77 days-91 days 8 6.52 x 1000 cells/ul 0.73 2.08 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41531 401
FHH-Chr 15BN/Mcwi blood eosinophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity male 77 days-91 days 8 0.07 x 1000 cells/ul 0.02 0.05 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41675 401
FHH-Chr 15BN/Mcwi plasma anion gap controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait female 77 days-91 days 8 18.25 mmol/l 1.93 5.47 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38300 401
FHH-Chr 15BN/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 100.23 mmHg 9.96 24.4 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48652 461
FHH-Chr 15BN/Mcwi methylene blue metabolism-surface area product without auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 8 23.68 ml/min/kg 2.79 7.89 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57828 526
FHH-Chr 15BN/Mcwi methylene blue metabolism-surface area product without auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 23.66 ml/min/kg 1.75 5.24 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57839 526
FHH-Chr 15BN/Mcwi methylene blue to FAPGG metabolism-surface area product ratio controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 9 0.34 null 0.03 0.09 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58152 526
FHH-Chr 15BN/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait male 77 days-91 days 8 0.03 mmHg-1 0.01 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 58517 526
FHH-Chr 15BN/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait female 77 days-91 days 9 0.02 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 58528 526
FHH-Chr 15BN/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 7 101.56 mmHg 8.69 22.99 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45768 461
FHH-Chr 15BN/Mcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 45.08 % 2.81 7.96 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47105 461
FHH-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 6 159.17 beats/min 15.56 38.11 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45187 461
FHH-Chr 15BN/Mcwi serum alkaline phosphatase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount male 77 days-91 days 8 454.5 U/l 16.52 46.71 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36407 401
FHH-Chr 15BN/Mcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 9 0.32 ml 0.03 0.1 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13963 381
FHH-Chr 15BN/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 27.01 mmHg 7.1 17.4 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45298 461
FHH-Chr 15BN/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 6.29 ml/min/g 1.13 3.18 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44746 461
FHH-Chr 15BN/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 5 40.89 mmHg 7.0 15.65 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46456 461
FHH-Chr 15BN/Mcwi serum total bilirubin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount male 77 days-91 days 8 0.13 mg/dl 0.02 0.06 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 41896 401
FHH-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 8 197.99 beats/min 17.55 49.65 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47621 461
FHH-Chr 15BN/Mcwi serum chloride level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount female 77 days-91 days 8 107.5 mmol/l 0.71 2.0 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39156 401