Phenominer Database Results (152 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Experiment Notes Record ID Study ID
FHH-Chr 14BN/Mcwi percent change in ventilation air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 %change=VE during 2-3 min hypoxia/control during standard conditions 141.18 % 7.7 24.34 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13722 381
FHH-Chr 14BN/Mcwi minute ventilation air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 37.25 ml/min 2.39 7.56 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18704 381
FHH-Chr 14BN/Mcwi serum calcium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount female 77 days-91 days 8 9.24 mg/dl 0.16 0.46 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36655 401
FHH-Chr 14BN/Mcwi time to onset of heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 6 965.13 s 35.13 86.06 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49340 461
FHH-Chr 14BN/Mcwi heart contraction pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 6 25.83 mmHg 6.05 14.81 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50038 461
FHH-Chr 14BN/Mcwi mean corpuscular volume air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait female 77 days-91 days 8 58.31 fl 0.44 1.24 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38776 401
FHH-Chr 14BN/Mcwi serum bicarbonate level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount male 77 days-91 days 8 20.75 mmol/l 0.96 2.71 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42103 401
FHH-Chr 14BN/Mcwi body weight air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass female 77 days-91 days 10 103.8 g 4.0 12.6 whole body digital scale 0 Moms and pups used in studies were fed Teklad 59093 526
FHH-Chr 14BN/Mcwi blood lymphocyte count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity female 77 days-91 days 8 4.57 x 1000 cells/ul 0.44 1.24 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41534 401
FHH-Chr 14BN/Mcwi plasma anion gap air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait female 77 days-91 days 8 18.0 mmol/l 1.27 3.59 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38292 401
FHH-Chr 14BN/Mcwi methylene blue metabolism-surface area product after auto-oxidation air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 5 17.5 ml/min/kg 1.12 2.5 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57629 526
FHH-Chr 14BN/Mcwi methylene blue metabolism-surface area product after auto-oxidation air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 9 15.97 ml/min/kg 0.99 2.96 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57639 526
FHH-Chr 14BN/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait female 77 days-91 days 5 0.02 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 58520 526
FHH-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 4 0.39 IU/g 0.19 0.39 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47425 461
FHH-Chr 14BN/Mcwi percent change in heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 92.92 % 3.0 7.34 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48336 461
FHH-Chr 14BN/Mcwi tidal volume air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 0.22 ml 0.02 0.06 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 15264 381
FHH-Chr 14BN/Mcwi minute ventilation air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 30.53 ml/min 1.58 5.0 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 20250 381
FHH-Chr 14BN/Mcwi serum chloride level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount female 77 days-91 days 8 111.63 mmol/l 0.71 2.0 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39148 401
FHH-Chr 14BN/Mcwi percent change in respiration rate air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 137.23 % 9.0 28.45 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54368 381
FHH-Chr 14BN/Mcwi blood neutrophil count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity female 77 days-91 days 8 0.87 x 1000 cells/ul 0.15 0.42 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 43255 401
FHH-Chr 14BN/Mcwi total white blood cell count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity female 77 days-91 days 8 5.71 x 1000 cells/ul 0.43 1.23 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 40957 401
FHH-Chr 14BN/Mcwi serum urea nitrogen level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount male 77 days-91 days 8 27.63 mg/dl 2.1 5.93 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40869 401
FHH-Chr 14BN/Mcwi heart wet weight air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49 days-63 days 9 0.52 g 0.04 0.13 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45436 461
FHH-Chr 14BN/Mcwi FAPGG metabolism-surface area product air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 5 59.0 ml/min/kg 5.23 11.69 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58030 526
FHH-Chr 14BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 4 8.09 ml/min/g 1.77 3.54 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44749 461
FHH-Chr 14BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 6 6.86 ml/min/g 0.93 2.29 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44759 461
FHH-Chr 14BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 4 17.65 ml/min/g 3.77 7.54 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46684 461
FHH-Chr 14BN/Mcwi serum total cholesterol level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount female 77 days-91 days 8 69.13 mg/dl 2.86 8.1 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37128 401
FHH-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 0.68 IU/g 0.21 0.52 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47441 461
FHH-Chr 14BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 22.9 mmHg 7.87 19.29 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45311 461
FHH-Chr 14BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49 days-63 days 4 2.93 % 0.37 0.75 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49729 461
FHH-Chr 14BN/Mcwi heart wet weight air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49 days-63 days 9 0.57 g 0.05 0.14 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45446 461
FHH-Chr 14BN/Mcwi time to peak heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 6 1179.56 s 29.65 72.63 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50268 461
FHH-Chr 14BN/Mcwi body weight air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass female 49 days-63 days 9 84.3 g 7.4 22.1 whole body digital scale 0 Moms and pups used in studies were fed Teklad 49495 461
FHH-Chr 14BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 69.74 mmHg 11.13 27.26 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49929 461
FHH-Chr 14BN/Mcwi body weight air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass male 77 days-91 days 10 116.3 g 5.3 16.7 whole body digital scale 0 Moms and pups used in studies were fed Teklad 59103 526
FHH-Chr 14BN/Mcwi blood eosinophil count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity male 77 days-91 days 8 0.05 x 1000 cells/ul 0.02 0.06 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41688 401
FHH-Chr 14BN/Mcwi percent change in left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 92.41 % 7.05 17.26 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48797 461
FHH-Chr 14BN/Mcwi percent change in arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 53.84 % 4.3 10.53 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47118 461
FHH-Chr 14BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 4 4.82 mmHg 0.35 0.7 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47228 461
FHH-Chr 14BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 5.25 mmHg 0.32 0.79 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47238 461
FHH-Chr 14BN/Mcwi percent change in tidal volume air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 110.08 % 5.25 16.59 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54018 381
FHH-Chr 14BN/Mcwi percent change in ventilation air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 %change=VE during 2-3 min hypoxia/control during standard conditions 138.21 % 7.13 22.54 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13711 381
FHH-Chr 14BN/Mcwi tidal volume air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 0.21 ml 0.02 0.05 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13954 381
FHH-Chr 14BN/Mcwi percent change in respiration rate air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 10 104.41 % 4.44 14.05 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53785 381
FHH-Chr 14BN/Mcwi minute ventilation air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 29.87 ml/min 3.14 9.94 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 20239 381
FHH-Chr 14BN/Mcwi serum aspartate aminotransferase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount male 77 days-91 days 8 112.0 U/l 9.98 28.22 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42811 401
FHH-Chr 14BN/Mcwi serum alanine aminotransferase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount male 77 days-91 days 8 97.25 U/l 9.68 27.38 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40755 401
FHH-Chr 14BN/Mcwi serum globulin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount male 77 days-91 days 8 1.76 g/dl 0.05 0.13 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40591 401
FHH-Chr 14BN/Mcwi serum phosphate level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount female 77 days-91 days 8 10.54 mg/dl 0.54 1.52 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37625 401
FHH-Chr 14BN/Mcwi serum phosphate level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount male 77 days-91 days 8 9.19 mg/dl 0.38 1.08 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37635 401
FHH-Chr 14BN/Mcwi serum urea nitrogen level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount female 77 days-91 days 8 29.75 mg/dl 2.6 7.36 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40859 401
FHH-Chr 14BN/Mcwi blood hemoglobin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 8 16.99 g/dl 0.39 1.1 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38009 401
FHH-Chr 14BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 4 41.83 mmHg 5.18 10.36 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46448 461
FHH-Chr 14BN/Mcwi serum glucose level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount female 77 days-91 days 7 136.14 mg/dl 3.73 9.87 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38561 401
FHH-Chr 14BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 4 82.31 mmHg 13.08 26.17 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48655 461
FHH-Chr 14BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 46.84 mmHg 6.37 15.61 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46458 461
FHH-Chr 14BN/Mcwi lung dry weight to body weight ratio air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass male 77 days-91 days 10 1.55 g/kg 0.02 0.07 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 59698 526
FHH-Chr 14BN/Mcwi FAPGG metabolism-surface area product air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 9 53.12 ml/min/kg 3.89 11.67 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58040 526
FHH-Chr 14BN/Mcwi serum potassium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount female 77 days-91 days 8 4.61 mmol/l 0.36 1.01 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38097 401
FHH-Chr 14BN/Mcwi tidal volume air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 0.22 ml 0.01 0.04 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 13965 381
FHH-Chr 14BN/Mcwi serum alkaline phosphatase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount female 77 days-91 days 8 394.63 U/l 23.83 67.4 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36410 401
FHH-Chr 14BN/Mcwi respiration rate air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 172.82 breaths/min 12.66 40.03 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18307 381
FHH-Chr 14BN/Mcwi serum total protein level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount male 77 days-91 days 8 4.74 g/dl 0.12 0.34 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37003 401
FHH-Chr 14BN/Mcwi serum total cholesterol level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount male 77 days-91 days 8 68.25 mg/dl 4.17 11.79 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 37138 401
FHH-Chr 14BN/Mcwi serum calcium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount male 77 days-91 days 8 8.85 mg/dl 0.12 0.33 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36665 401
FHH-Chr 14BN/Mcwi heart contraction pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 4 17.5 mmHg 4.09 8.19 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50028 461
FHH-Chr 14BN/Mcwi hematocrit air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77 days-91 days 8 51.7 % 1.2 3.4 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39022 401
FHH-Chr 14BN/Mcwi hematocrit air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77 days-91 days 8 53.45 % 1.15 3.24 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39032 401
FHH-Chr 14BN/Mcwi serum potassium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount male 77 days-91 days 8 5.15 mmol/l 0.24 0.69 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38107 401
FHH-Chr 14BN/Mcwi calculated pulmonary vascular resistance normalized to body weight air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 9 0.14 mmHg x min x kg x ml-1 0.01 0.02 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 59588 526
FHH-Chr 14BN/Mcwi body temperature air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82 days-99 days 10 37.31 degrees C 0.18 0.57 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 16614 381
FHH-Chr 14BN/Mcwi heart right ventricle weight to left ventricle weight ratio air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass male 77 days-91 days 10 0.48 null 0.02 0.06 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 58774 526
FHH-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 4 15.19 IU/g 1.83 3.66 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45952 461
FHH-Chr 14BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 6 15.63 IU/g 1.38 3.38 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45962 461
FHH-Chr 14BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 4 87.13 mmHg 12.99 25.99 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45760 461
FHH-Chr 14BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 12.66 ml/min/g 1.06 2.99 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46694 461
FHH-Chr 14BN/Mcwi tidal volume air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 0.21 ml 0.01 0.04 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 15275 381
FHH-Chr 14BN/Mcwi respiration rate air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 10 169.41 breaths/min 8.23 26.03 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18296 381
FHH-Chr 14BN/Mcwi absolute change in body temperature air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82 days-99 days 10 0.16 degrees C 0.16 0.51 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 20340 381
FHH-Chr 14BN/Mcwi serum sodium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount female 77 days-91 days 8 145.63 mmol/l 0.46 1.3 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39419 401
FHH-Chr 14BN/Mcwi mean corpuscular hemoglobin air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 8 18.64 pg 0.08 0.21 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 42576 401
FHH-Chr 14BN/Mcwi red blood cell count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77 days-91 days 8 9.28 x 10E6 cells/ul 0.25 0.7 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39278 401
FHH-Chr 14BN/Mcwi percent change in respiration rate air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 10 131.67 % 5.51 17.41 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54358 381
FHH-Chr 14BN/Mcwi blood neutrophil count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity male 77 days-91 days 8 1.11 x 1000 cells/ul 0.15 0.43 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 43265 401
FHH-Chr 14BN/Mcwi plasma creatinine level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount male 77 days-91 days 8 0.3 mg/dl 0.03 0.08 automated plasma creatinine analysis 0 Moms and pups used in studies were fed Teklad 39617 401
FHH-Chr 14BN/Mcwi serum alanine aminotransferase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount female 77 days-91 days 8 83.38 U/l 4.4 12.43 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 40745 401
FHH-Chr 14BN/Mcwi methylene blue metabolism-surface area product without auto-oxidation air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 8 25.55 ml/min/kg 2.46 6.96 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57841 526
FHH-Chr 14BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 6 204.34 beats/min 11.08 27.13 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45189 461
FHH-Chr 14BN/Mcwi serum total protein level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount female 77 days-91 days 8 4.78 g/dl 0.1 0.29 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36993 401
FHH-Chr 14BN/Mcwi heart weight to body weight ratio air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49 days-63 days 9 6.5 g/kg 0.53 1.58 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45609 461
FHH-Chr 14BN/Mcwi serum aspartate aminotransferase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount female 77 days-91 days 8 96.25 U/l 3.6 10.19 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42801 401
FHH-Chr 14BN/Mcwi heart weight to body weight ratio air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49 days-63 days 9 6.28 g/kg 0.43 1.28 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 45593 461
FHH-Chr 14BN/Mcwi percent change in left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 4 post-ischemic value/pre-ischemic value x 100% 79.11 % 8.13 16.25 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48787 461
FHH-Chr 14BN/Mcwi red blood cell count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77 days-91 days 8 8.87 x 10E6 cells/ul 0.21 0.61 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39268 401
FHH-Chr 14BN/Mcwi serum alkaline phosphatase activity level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount male 77 days-91 days 8 405.75 U/l 24.89 70.41 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 36420 401
FHH-Chr 14BN/Mcwi mean corpuscular hemoglobin air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 8 18.31 pg 0.12 0.33 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 42586 401
FHH-Chr 14BN/Mcwi blood monocyte count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity female 77 days-91 days 8 0.22 x 1000 cells/ul 0.05 0.15 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39705 401
FHH-Chr 14BN/Mcwi mean corpuscular hemoglobin concentration air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77 days-91 days 8 31.75 g/dl 0.16 0.45 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39818 401
FHH-Chr 14BN/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait female 77 days-91 days 6 4.44 mg/kg 1.7 4.17 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 58937 526
FHH-Chr 14BN/Mcwi calculated pulmonary vascular resistance normalized to body weight air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 5 0.14 mmHg x min x kg x ml-1 0.01 0.02 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 59578 526
FHH-Chr 14BN/Mcwi lung dry weight to body weight ratio air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass female 77 days-91 days 9 1.81 g/kg 0.09 0.27 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 59688 526
FHH-Chr 14BN/Mcwi percent change in left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 32.87 % 7.74 18.97 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48568 461
FHH-Chr 14BN/Mcwi serum total bilirubin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount female 77 days-91 days 8 0.11 mg/dl 0.01 0.04 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 41899 401
FHH-Chr 14BN/Mcwi percent change in left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 4 post-ischemic value/pre-ischemic value x 100% 32.27 % 6.26 12.53 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48558 461
FHH-Chr 14BN/Mcwi serum glucose level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount male 77 days-91 days 8 152.63 mg/dl 8.09 22.87 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38571 401
FHH-Chr 14BN/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait male 77 days-91 days 9 0.02 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung 0 Moms and pups used in studies were fed Teklad 58530 526
FHH-Chr 14BN/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait male 77 days-91 days 7 3.38 mg/kg 0.87 2.31 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 58947 526
FHH-Chr 14BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 77.74 mmHg 12.99 31.81 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45770 461
FHH-Chr 14BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 4 24.32 mmHg 2.27 4.55 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45301 461
FHH-Chr 14BN/Mcwi percent change in respiration rate air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 120.57 % 6.67 21.1 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53795 381
FHH-Chr 14BN/Mcwi minute ventilation air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 35.66 ml/min 3.32 10.48 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 18693 381
FHH-Chr 14BN/Mcwi serum albumin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount female 77 days-91 days 8 3.06 g/dl 0.05 0.15 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42264 401
FHH-Chr 14BN/Mcwi serum globulin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount female 77 days-91 days 8 1.71 g/dl 0.05 0.16 standard blood chemistry panel 0 replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40581 401
FHH-Chr 14BN/Mcwi hematocrit air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity female 77 days-91 days 8 51.7 % 1.2 3.4 microhematocrit tube assay with visual assessment 0 Moms and pups used in studies were fed Teklad 59288 526
FHH-Chr 14BN/Mcwi blood lymphocyte count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity male 77 days-91 days 8 4.72 x 1000 cells/ul 0.41 1.17 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41544 401
FHH-Chr 14BN/Mcwi plasma anion gap air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait male 77 days-91 days 8 17.25 mmol/l 0.53 1.49 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 38302 401
FHH-Chr 14BN/Mcwi blood eosinophil count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity female 77 days-91 days 8 0.05 x 1000 cells/ul 0.02 0.06 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 41678 401
FHH-Chr 14BN/Mcwi methylene blue metabolism-surface area product without auto-oxidation air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 5 28.69 ml/min/kg 2.06 4.61 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 57831 526
FHH-Chr 14BN/Mcwi methylene blue to FAPGG metabolism-surface area product ratio air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77 days-91 days 5 0.49 null 0.03 0.07 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58144 526
FHH-Chr 14BN/Mcwi methylene blue to FAPGG metabolism-surface area product ratio air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77 days-91 days 8 0.47 null 0.05 0.15 isolated perfused lung vascular effluent collection 0 Moms and pups used in studies were fed Teklad 58154 526
FHH-Chr 14BN/Mcwi percent change in heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 4 post-ischemic value/pre-ischemic value x 100% 102.69 % 11.67 23.35 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48326 461
FHH-Chr 14BN/Mcwi percent change in arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 4 post-ischemic value/pre-ischemic value x 100% 49.03 % 9.9 19.8 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47108 461
FHH-Chr 14BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 4 213.13 beats/min 13.85 27.7 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45179 461
FHH-Chr 14BN/Mcwi body temperature air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82 days-99 days 10 37.35 degrees C 0.22 0.71 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 16603 381
FHH-Chr 14BN/Mcwi plasma creatinine level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount female 77 days-91 days 8 0.26 mg/dl 0.03 0.07 automated plasma creatinine analysis 0 Moms and pups used in studies were fed Teklad 39607 401
FHH-Chr 14BN/Mcwi blood monocyte count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity male 77 days-91 days 8 0.27 x 1000 cells/ul 0.07 0.19 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39715 401
FHH-Chr 14BN/Mcwi body weight air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass male 49 days-63 days 9 88.4 g 6.0 18.1 whole body digital scale 0 Moms and pups used in studies were fed Teklad 49511 461
FHH-Chr 14BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 8 213.22 beats/min 17.47 49.41 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47623 461
FHH-Chr 14BN/Mcwi heart right ventricle weight to left ventricle weight ratio air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass female 77 days-91 days 10 0.53 null 0.02 0.08 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 58764 526
FHH-Chr 14BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 72.49 mmHg 13.13 32.16 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48665 461
FHH-Chr 14BN/Mcwi serum bicarbonate level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount female 77 days-91 days 8 20.75 mmol/l 0.65 1.83 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42093 401
FHH-Chr 14BN/Mcwi percent change in tidal volume air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82 days-99 days 10 105.24 % 4.43 14.02 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53917 381
FHH-Chr 14BN/Mcwi absolute change in body temperature air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82 days-99 days 10 0.04 degrees C 0.12 0.37 digital rectal thermometry 0 Moms and pups used in studies were fed Teklad 20351 381
FHH-Chr 14BN/Mcwi serum sodium level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount male 77 days-91 days 8 145.0 mmol/l 0.68 1.93 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39429 401
FHH-Chr 14BN/Mcwi mean corpuscular hemoglobin concentration air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 8 31.96 g/dl 0.17 0.48 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 39808 401
FHH-Chr 14BN/Mcwi hematocrit air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity male 77 days-91 days 8 53.45 % 1.15 3.24 microhematocrit tube assay with visual assessment 0 Moms and pups used in studies were fed Teklad 59298 526
FHH-Chr 14BN/Mcwi total white blood cell count air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity male 77 days-91 days 8 6.15 x 1000 cells/ul 0.49 1.38 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 40967 401
FHH-Chr 14BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49 days-63 days 5 3.86 % 0.78 1.75 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49739 461
FHH-Chr 14BN/Mcwi time to peak heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 4 1097.42 s 143.23 286.45 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50258 461
FHH-Chr 14BN/Mcwi time to onset of heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 4 917.38 s 158.14 316.27 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49330 461
FHH-Chr 14BN/Mcwi mean corpuscular volume air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait male 77 days-91 days 8 57.73 fl 0.38 1.08 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 38786 401
FHH-Chr 14BN/Mcwi serum albumin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount male 77 days-91 days 8 2.98 g/dl 0.1 0.29 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 42274 401
FHH-Chr 14BN/Mcwi blood hemoglobin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77 days-91 days 8 16.52 g/dl 0.41 1.15 automated blood cell counting method 0 Moms and pups used in studies were fed Teklad 37999 401
FHH-Chr 14BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 4 212.65 beats/min 17.6 35.21 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47613 461
FHH-Chr 14BN/Mcwi percent change in tidal volume air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 104.43 % 4.94 15.62 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 53927 381
FHH-Chr 14BN/Mcwi percent change in tidal volume air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82 days-99 days 10 97.52 % 4.43 14.02 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 54028 381
FHH-Chr 14BN/Mcwi respiration rate air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82 days-99 days 10 134.21 breaths/min 6.41 20.26 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 14825 381
FHH-Chr 14BN/Mcwi respiration rate air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82 days-99 days 10 149.55 breaths/min 3.37 10.66 stop flow air displacement plethysmography 0 Moms and pups used in studies were fed Teklad 14836 381
FHH-Chr 14BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 4 66.14 mmHg 6.02 12.04 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49919 461
FHH-Chr 14BN/Mcwi serum total bilirubin level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount male 77 days-91 days 8 0.1 mg/dl 0.0 0.0 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 41909 401
FHH-Chr 14BN/Mcwi serum chloride level air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount male 77 days-91 days 8 112.38 mmol/l 0.38 1.06 standard blood chemistry panel 0 Moms and pups used in studies were fed Teklad 39158 401