| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
male |
90.0 days-120.0 days |
7 |
11.95 |
gx10 |
0.91 |
2.41 |
Randall-Selitto test |
|
120 |
min |
0.1% methylcellulose per os |
108223 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
male |
90.0 days-120.0 days |
7 |
13.23 |
gx10 |
1.01 |
2.68 |
Randall-Selitto test |
|
90 |
min |
0.1% methylcellulose per os |
108221 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
estrus then diclofenac (40 mg/kg) (for 0.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
8.39 |
gx10 |
0.37 |
0.97 |
Randall-Selitto test |
|
30 |
min |
0.1% methylcellulose per os |
108244 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
estrus then diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
8.94 |
gx10 |
0.54 |
1.44 |
Randall-Selitto test |
|
150 |
min |
0.1% methylcellulose per os |
108252 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
metestrus then diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
10.11 |
gx10 |
0.65 |
1.72 |
Randall-Selitto test |
|
60 |
min |
0.1% methylcellulose per os |
108260 |
3101 |
| SHR |
systolic blood pressure |
proestrus then diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
166.83 |
mmHg |
1.0 |
2.64 |
tail cuff plethysmography |
|
|
|
|
108298 |
3101 |
| SHR |
systolic blood pressure |
proestrus then diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
161.67 |
mmHg |
3.51 |
9.29 |
tail cuff plethysmography |
|
|
|
|
108306 |
3101 |
| SHR |
systolic blood pressure |
estrus then diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
164.0 |
mmHg |
2.97 |
7.85 |
tail cuff plethysmography |
|
|
|
|
108310 |
3101 |
| SHR |
systolic blood pressure |
estrus then diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
161.86 |
mmHg |
1.49 |
3.93 |
tail cuff plethysmography |
|
|
|
|
108316 |
3101 |
| SHR |
systolic blood pressure |
metestrus then diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
165.86 |
mmHg |
3.28 |
8.67 |
tail cuff plethysmography |
|
|
|
|
108330 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
male |
90.0 days-120.0 days |
7 |
9.77 |
gx10 |
0.83 |
2.2 |
Randall-Selitto test |
0.0 |
180 |
min |
0.1% methylcellulose per os |
108227 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
proestrus then diclofenac (40 mg/kg) (for 0.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
10.08 |
gx10 |
0.91 |
2.41 |
Randall-Selitto test |
|
30 |
min |
0.1% methylcellulose per os |
108230 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
male |
90.0 days-120.0 days |
7 |
11.03 |
gx10 |
1.01 |
2.66 |
Randall-Selitto test |
|
60 |
min |
0.1% methylcellulose per os |
108219 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
proestrus then diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
8.96 |
gx10 |
0.7 |
1.86 |
Randall-Selitto test |
|
180 |
min |
0.1% methylcellulose per os |
108240 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
metestrus then diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
11.87 |
gx10 |
0.57 |
1.52 |
Randall-Selitto test |
|
90 |
min |
0.1% methylcellulose per os |
108262 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
metestrus then diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
8.99 |
gx10 |
0.39 |
1.02 |
Randall-Selitto test |
|
150 |
min |
0.1% methylcellulose per os |
108266 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diestrus then diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
11.2 |
gx10 |
0.56 |
1.49 |
Randall-Selitto test |
|
90 |
min |
0.1% methylcellulose per os |
108276 |
3101 |
| SHR |
systolic blood pressure |
diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
male |
90.0 days-120.0 days |
7 |
155.93 |
mmHg |
7.57 |
20.02 |
tail cuff plethysmography |
|
180 |
min |
0.1% methylcellulose per os |
108294 |
3101 |
| SHR |
systolic blood pressure |
estrus then diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
160.29 |
mmHg |
2.08 |
5.5 |
tail cuff plethysmography |
|
|
|
|
108312 |
3101 |
| SHR |
systolic blood pressure |
metestrus then diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
162.14 |
mmHg |
1.74 |
4.6 |
tail cuff plethysmography |
|
|
|
|
108328 |
3101 |
| SHR |
systolic blood pressure |
diestrus then diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
151.71 |
mmHg |
4.22 |
11.16 |
tail cuff plethysmography |
|
|
|
|
108336 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
male |
90.0 days-120.0 days |
7 |
11.03 |
gx10 |
0.63 |
1.66 |
Randall-Selitto test |
0.0 |
60 |
min |
0.1% methylcellulose per os |
108354 |
3101 |
| SHR |
systolic blood pressure |
diclofenac (10 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
male |
90.0 days-120.0 days |
7 |
165.9 |
mmHg |
1.59 |
4.2 |
tail cuff plethysmography |
|
60 |
min |
IP |
108358 |
3101 |
| SHR |
systolic blood pressure |
diclofenac (20 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
male |
90.0 days-120.0 days |
7 |
160.57 |
mmHg |
5.22 |
13.81 |
tail cuff plethysmography |
|
60 |
min |
0.1% methylcellulose per os |
108362 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
proestrus then diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
12.69 |
gx10 |
0.96 |
2.54 |
Randall-Selitto test |
|
90 |
min |
0.1% methylcellulose per os |
108234 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
proestrus then diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
10.61 |
gx10 |
1.14 |
3.02 |
Randall-Selitto test |
|
60 |
min |
0.1% methylcellulose per os |
108232 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
proestrus then diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
10.09 |
gx10 |
0.66 |
1.75 |
Randall-Selitto test |
|
150 |
min |
0.1% methylcellulose per os |
108238 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
estrus then diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
10.31 |
gx10 |
0.49 |
1.3 |
Randall-Selitto test |
|
120 |
min |
0.1% methylcellulose per os |
108250 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
estrus then diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
9.33 |
gx10 |
0.66 |
1.75 |
Randall-Selitto test |
|
60 |
min |
0.1% methylcellulose per os |
108246 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
metestrus then diclofenac (40 mg/kg) (for 0.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
9.26 |
gx10 |
0.35 |
0.92 |
Randall-Selitto test |
|
30 |
min |
0.1% methylcellulose per os |
108258 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
metestrus then diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
10.86 |
gx10 |
0.7 |
1.84 |
Randall-Selitto test |
|
120 |
min |
0.1% methylcellulose per os |
108264 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diestrus then diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
9.91 |
gx10 |
0.36 |
0.95 |
Randall-Selitto test |
|
60 |
min |
0.1% methylcellulose per os |
108274 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diestrus then diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
8.86 |
gx10 |
0.57 |
1.5 |
Randall-Selitto test |
|
150 |
min |
0.1% methylcellulose per os |
108280 |
3101 |
| SHR |
systolic blood pressure |
diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
male |
90.0 days-120.0 days |
7 |
143.18 |
mmHg |
9.25 |
24.48 |
tail cuff plethysmography |
|
90 |
min |
0.1% methylcellulose per os |
108288 |
3101 |
| SHR |
systolic blood pressure |
diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
male |
90.0 days-120.0 days |
7 |
149.29 |
mmHg |
7.17 |
18.98 |
tail cuff plethysmography |
|
150 |
min |
0.1% methylcellulose per os |
108292 |
3101 |
| SHR |
systolic blood pressure |
proestrus then diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
160.67 |
mmHg |
1.11 |
2.94 |
tail cuff plethysmography |
|
|
|
|
108300 |
3101 |
| SHR |
systolic blood pressure |
proestrus then diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
162.67 |
mmHg |
1.61 |
4.27 |
tail cuff plethysmography |
|
|
|
|
108302 |
3101 |
| SHR |
systolic blood pressure |
proestrus then diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
162.33 |
mmHg |
0.62 |
1.63 |
tail cuff plethysmography |
|
|
|
|
108304 |
3101 |
| SHR |
systolic blood pressure |
estrus then diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
163.71 |
mmHg |
2.21 |
5.85 |
tail cuff plethysmography |
|
|
|
|
108318 |
3101 |
| SHR |
systolic blood pressure |
diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
male |
90.0 days-120.0 days |
7 |
155.11 |
mmHg |
9.41 |
24.89 |
tail cuff plethysmography |
|
60 |
min |
0.1% methylcellulose per os |
108366 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
male |
90.0 days-120.0 days |
7 |
10.99 |
gx10 |
0.89 |
2.36 |
Randall-Selitto test |
|
150 |
min |
0.1% methylcellulose per os |
108225 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
estrus then diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
7.56 |
gx10 |
0.38 |
1.0 |
Randall-Selitto test |
0.0 |
180 |
min |
0.1% methylcellulose per os |
108254 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
metestrus then diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
8.4 |
gx10 |
0.34 |
0.9 |
Randall-Selitto test |
|
180 |
min |
0.1% methylcellulose per os |
108268 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diestrus then diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
8.01 |
gx10 |
0.29 |
0.78 |
Randall-Selitto test |
|
180 |
min |
0.1% methylcellulose per os |
108282 |
3101 |
| SHR |
systolic blood pressure |
estrus then diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
161.57 |
mmHg |
1.0 |
2.64 |
tail cuff plethysmography |
|
|
|
|
108314 |
3101 |
| SHR |
systolic blood pressure |
metestrus then diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
171.86 |
mmHg |
5.62 |
14.86 |
tail cuff plethysmography |
|
|
|
|
108322 |
3101 |
| SHR |
systolic blood pressure |
metestrus then diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
163.71 |
mmHg |
5.52 |
14.6 |
tail cuff plethysmography |
|
|
|
|
108324 |
3101 |
| SHR |
systolic blood pressure |
metestrus then diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
159.14 |
mmHg |
2.35 |
6.23 |
tail cuff plethysmography |
|
|
|
|
108326 |
3101 |
| SHR |
systolic blood pressure |
diestrus then diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
163.71 |
mmHg |
6.11 |
16.16 |
tail cuff plethysmography |
|
|
|
|
108334 |
3101 |
| SHR |
systolic blood pressure |
diestrus then diclofenac (40 mg/kg) (for 3 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
162.57 |
mmHg |
4.24 |
11.22 |
tail cuff plethysmography |
|
|
|
|
108342 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diclofenac (10 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
male |
90.0 days-120.0 days |
7 |
10.1 |
gx10 |
0.42 |
1.12 |
Randall-Selitto test |
|
60 |
min |
0.1% methylcellulose per os |
108346 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
proestrus then diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
12.06 |
gx10 |
0.76 |
2.0 |
Randall-Selitto test |
|
120 |
min |
0.1% methylcellulose per os |
108236 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
estrus then diclofenac (40 mg/kg) (for 1.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
11.37 |
gx10 |
0.86 |
2.27 |
Randall-Selitto test |
|
90 |
min |
0.1% methylcellulose per os |
108248 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diestrus then diclofenac (40 mg/kg) (for 0.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
9.14 |
gx10 |
0.43 |
1.14 |
Randall-Selitto test |
|
30 |
min |
0.1% methylcellulose per os |
108272 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diestrus then diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
female |
90.0 days-120.0 days |
7 |
10.91 |
gx10 |
0.55 |
1.45 |
Randall-Selitto test |
|
120 |
min |
0.1% methylcellulose per os |
108278 |
3101 |
| SHR |
systolic blood pressure |
diclofenac (40 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
male |
90.0 days-120.0 days |
7 |
155.11 |
mmHg |
9.41 |
24.89 |
tail cuff plethysmography |
|
60 |
min |
0.1% methylcellulose per os |
108286 |
3101 |
| SHR |
systolic blood pressure |
diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
male |
90.0 days-120.0 days |
7 |
143.46 |
mmHg |
7.11 |
18.8 |
tail cuff plethysmography |
|
120 |
min |
0.1% methylcellulose per os |
108290 |
3101 |
| SHR |
systolic blood pressure |
diestrus then diclofenac (40 mg/kg) (for 2 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
152.14 |
mmHg |
2.52 |
6.67 |
tail cuff plethysmography |
|
|
|
|
108338 |
3101 |
| SHR |
systolic blood pressure |
diestrus then diclofenac (40 mg/kg) (for 2.5 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
arterial blood pressure trait |
female |
90.0 days-120.0 days |
7 |
161.14 |
mmHg |
4.01 |
10.62 |
tail cuff plethysmography |
|
|
|
|
108340 |
3101 |
| SHR |
measurement of minimal mechanical stimulus needed to elicit evasive reaction |
diclofenac (20 mg/kg) (for 1 hours) |
Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. |
tactile sensory behavior trait |
male |
90.0 days-120.0 days |
7 |
10.11 |
gx10 |
0.56 |
1.49 |
Randall-Selitto test |
|
60 |
min |
0.1% methylcellulose per os |
108350 |
3101 |