Phenominer Database Results (88 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 147.0 days 8 4.37 g/d/100g 0.23 0.66 unspecified method 0.0 on days 74-77 85510 1604
Crl:CD(SD) body weight standard diet then acetaminophen (500 mg/kg) (for 1 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 71.0 days 8 375.0 g 6.36 18.0 body weighing method 0.0 85520 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 1 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 71.0 days 8 287.0 g 5.3 15.0 body weighing method 0.0 85523 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 168.0 days 8 447.0 g 16.62 47.0 body weighing method 0.0 85552 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 168.0 days 8 18.3 g/d 1.98 5.6 unspecified method 0.0 85486 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (300 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 168.0 days 8 4.05 g/d/100g 0.08 0.24 unspecified method 0.0 on days 95-98 85513 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 1 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 71.0 days 8 287.0 g 6.72 19.0 body weighing method 0.0 85522 1604
Crl:CD(SD) body weight standard diet then acetaminophen (500 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 168.0 days 8 564.0 g 15.2 43.0 body weighing method 0.0 85550 1604
Crl:CD(SD) liver wet weight standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) then fasting (for 20 hours) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver mass male 170.0 days 8 12.8 g 0.22 0.61 unspecified method 0.0 85559 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 126.0 days 8 22.1 g/d 0.71 2.0 unspecified method 0.0 85474 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 147.0 days 8 4.03 g/d/100g 0.29 0.81 unspecified method 0.0 on days 74-77 85511 1604
Crl:CD(SD) body weight standard diet then acetaminophen (300 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 105.0 days 8 477.0 g 7.42 21.0 body weighing method 0.0 85531 1604
Crl:CD(SD) plasma acetaminophen level area under curve standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 500.6 (ug/ml) x h 64.42 182.2 high-performance liquid chromatography 0.0 acetaminophen dosing 1140 min 4-19 hr dosing 4-19 hr dosing 85589 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 105.0 days 8 16.7 g/d 0.95 2.7 unspecified method 0.0 85469 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 84.0 days 8 6.04 g/d/100g 0.21 0.58 unspecified method 0.0 on days 11-14 85492 1604
Crl:CD(SD) plasma acetaminophen level area under curve standard diet then acetaminophen (500 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 893.3 (ug/ml) x h 44.55 126.0 high-performance liquid chromatography 0.0 acetaminophen dosing 1140 min 4-19 hr dosing 4-19 hr dosing 85587 1604
Crl:CD(SD) plasma acetaminophen level standard diet then acetaminophen (300 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 88.0 ug/ml 3.89 11.0 high-performance liquid chromatography 0.0 acetaminophen dosing 240 min 4 hr after dosing 85578 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 168.0 days 8 16.6 g/d 0.95 2.7 unspecified method 0.0 85487 1604
Crl:CD(SD) liver wet weight standard diet then acetaminophen (500 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver mass male 170.0 days 8 20.3 g 0.7 1.98 unspecified method 0.0 liver weight not available 85556 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (500 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 168.0 days 8 22.8 g/d 0.71 2.0 unspecified method 0.0 85484 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (500 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 105.0 days 8 5.12 g/d/100g 0.15 0.42 unspecified method 0.0 on days 32-35 85496 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 84.0 days 8 333.0 g 8.13 23.0 body weighing method 0.0 85528 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 105.0 days 8 375.0 g 12.73 36.0 body weighing method 0.0 85534 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 105.0 days 8 365.0 g 6.36 18.0 body weighing method 0.0 85535 1604
Crl:CD(SD) liver reduced glutathione level to liver weight ratio standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) then fasting (for 20 hours) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver glutathione amount male 170.0 days 8 5.19 umol/g 0.24 0.69 reduced glutathione/oxidized glutathione enzyme recycling assay 0.0 enzyme recycling method 85571 1604
Crl:CD(SD) plasma acetaminophen level standard diet then acetaminophen (500 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 1.1 ug/ml 0.32 0.9 high-performance liquid chromatography 0.0 acetaminophen dosing 1140 min 19 hr after dosing 85583 1604
Crl:CD(SD) liver reduced glutathione level to liver weight ratio standard diet then acetaminophen (300 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver glutathione amount male 170.0 days 8 9.16 umol/g 0.18 0.5 reduced glutathione/oxidized glutathione enzyme recycling assay 0.0 enzyme recycling method reduced liver glutathione level to liver weight ratio 85567 1604
Crl:CD(SD) body weight standard diet then acetaminophen (300 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 84.0 days 8 418.0 g 6.72 19.0 body weighing method 0.0 85525 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 147.0 days 8 432.0 g 17.32 49.0 body weighing method 0.0 85546 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 168.0 days 8 3.96 g/d/100g 0.35 0.98 unspecified method 0.0 on days 95-98 85516 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 84.0 days 8 20.3 g/d 1.06 3.0 unspecified method 0.0 85462 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (300 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 84.0 days 8 24.1 g/d 0.53 1.5 unspecified method 0.0 85459 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 84.0 days 8 18.8 g/d 0.92 2.6 unspecified method 0.0 85463 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (300 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 168.0 days 8 23.4 g/d 0.42 1.2 unspecified method 0.0 85483 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (300 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 84.0 days 8 5.74 g/d/100g 0.1 0.29 unspecified method 0.0 on days 11-14 85489 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (300 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 105.0 days 8 5.2 g/d/100g 0.07 0.21 unspecified method 0.0 on days 32-35 85495 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (500 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 126.0 days 8 4.53 g/d/100g 0.13 0.36 unspecified method 0.0 on days 53-56 85502 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 126.0 days 8 4.38 g/d/100g 0.31 0.87 unspecified method 0.0 on days 53-56 85504 1604
Crl:CD(SD) liver wet weight standard diet then acetaminophen (300 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver mass male 170.0 days 8 20.1 g 0.47 1.33 unspecified method 0.0 liver weight not available 85555 1604
Crl:CD(SD) plasma acetaminophen level area under curve standard diet then acetaminophen (300 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 662.2 (ug/ml) x h 28.35 80.2 high-performance liquid chromatography 0.0 acetaminophen dosing 1140 min 4-19 hr dosing 4-19 hr dosing 85586 1604
Crl:CD(SD) plasma acetaminophen level standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 2.4 ug/ml 0.71 2.0 high-performance liquid chromatography 0.0 acetaminophen dosing 1140 min 19 hr after dosing 85585 1604
Crl:CD(SD) plasma acetaminophen level area under curve standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 373.9 (ug/ml) x h 38.93 110.1 high-performance liquid chromatography 0.0 acetaminophen dosing 1140 min 4-19 hr dosing 4-19 hr dosing 85588 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (300 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 147.0 days 8 24.3 g/d 0.32 0.9 unspecified method 0.0 85477 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 105.0 days 8 4.9 g/d/100g 0.18 0.5 unspecified method 0.0 on days 32-35 85499 1604
Crl:CD(SD) liver oxidized glutathione level to liver weight ratio standard diet then acetaminophen (500 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver glutathione amount male 170.0 days 8 0.19 umol/g 0.01 0.03 reduced glutathione/oxidized glutathione enzyme recycling assay 0.0 enzyme recycling method reduced liver glutathione level to liver weight ratio 85574 1604
Crl:CD(SD) liver wet weight standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) then fasting (for 20 hours) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver mass male 170.0 days 8 12.2 g 0.77 2.17 unspecified method 0.0 85558 1604
Crl:CD(SD) liver oxidized glutathione level to liver weight ratio standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) then fasting (for 20 hours) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver glutathione amount male 170.0 days 8 0.16 umol/g 0.01 0.03 reduced glutathione/oxidized glutathione enzyme recycling assay 0.0 enzyme recycling method 85576 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (500 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 84.0 days 8 24.7 g/d 0.46 1.3 unspecified method 0.0 85460 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 105.0 days 8 18.2 g/d 1.13 3.2 unspecified method 0.0 85468 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 105.0 days 8 5.09 g/d/100g 0.24 0.67 unspecified method 0.0 on days 32-35 85498 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (300 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 126.0 days 8 4.7 g/d/100g 0.06 0.17 unspecified method 0.0 on days 53-56 85501 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (300 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 147.0 days 8 4.09 g/d/100g 0.45 1.28 unspecified method 0.0 on days 74-77 85507 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (500 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 147.0 days 8 4.49 g/d/100g 0.08 0.23 unspecified method 0.0 on days 74-77 85508 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 126.0 days 8 4.23 g/d/100g 0.27 0.77 unspecified method 0.0 on days 53-56 85505 1604
Crl:CD(SD) body weight standard diet then acetaminophen (300 mg/kg) (for 1 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 71.0 days 8 371.0 g 5.66 16.0 body weighing method 0.0 85519 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 84.0 days 8 321.0 g 7.78 22.0 body weighing method 0.0 85529 1604
Crl:CD(SD) body weight standard diet then acetaminophen (300 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 126.0 days 8 522.0 g 8.13 23.0 body weighing method 0.0 85537 1604
Crl:CD(SD) body weight standard diet then acetaminophen (500 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 126.0 days 8 516.0 g 12.73 36.0 body weighing method 0.0 85538 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 126.0 days 8 404.0 g 12.37 35.0 body weighing method 0.0 85540 1604
Crl:CD(SD) body weight standard diet then acetaminophen (300 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 147.0 days 8 557.0 g 8.13 23.0 body weighing method 0.0 85543 1604
Crl:CD(SD) body weight standard diet then acetaminophen (300 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 168.0 days 8 581.0 g 9.19 26.0 body weighing method 0.0 85549 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (500 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 147.0 days 8 24.5 g/d 0.32 0.9 unspecified method 0.0 85478 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 84.0 days 8 6.04 g/d/100g 0.23 0.66 unspecified method 0.0 on days 11-14 85493 1604
Crl:CD(SD) body weight standard diet then acetaminophen (500 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 84.0 days 8 413.0 g 6.01 17.0 body weighing method 0.0 85526 1604
Crl:CD(SD) plasma acetaminophen level standard diet then acetaminophen (500 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 118.1 ug/ml 6.43 18.2 high-performance liquid chromatography 0.0 acetaminophen dosing 240 min 4 hr after dosing 85579 1604
Crl:CD(SD) liver reduced glutathione level to liver weight ratio standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) then fasting (for 20 hours) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver glutathione amount male 170.0 days 8 6.24 umol/g 0.31 0.87 reduced glutathione/oxidized glutathione enzyme recycling assay 0.0 enzyme recycling method 85570 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (500 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 126.0 days 8 24.9 g/d 0.85 2.4 unspecified method 0.0 85472 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 126.0 days 8 18.7 g/d 1.45 4.1 unspecified method 0.0 85475 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 147.0 days 8 431.0 g 8.49 24.0 body weighing method 0.0 85547 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (500 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 105.0 days 8 25.7 g/d 0.28 0.8 unspecified method 0.0 85466 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (300 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 105.0 days 8 24.5 g/d 0.57 1.6 unspecified method 0.0 85465 1604
Crl:CD(SD) food intake rate standard diet then acetaminophen (300 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 126.0 days 8 24.6 g/d 0.21 0.6 unspecified method 0.0 85471 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 147.0 days 8 17.9 g/d 1.77 5.0 unspecified method 0.0 85480 1604
Crl:CD(SD) body weight standard diet then acetaminophen (500 mg/kg) (for 35 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 105.0 days 8 472.0 g 8.49 24.0 body weighing method 0.0 85532 1604
Crl:CD(SD) body weight standard diet then acetaminophen (500 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 147.0 days 8 549.0 g 12.73 36.0 body weighing method 0.0 85544 1604
Crl:CD(SD) food intake rate standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 77 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 147.0 days 8 17.7 g/d 1.31 3.7 unspecified method 0.0 85481 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (500 mg/kg) (for 14 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 84.0 days 8 5.68 g/d/100g 0.06 0.17 unspecified method 0.0 on days 11-14 85490 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 56 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 126.0 days 8 400.0 g 7.78 22.0 body weighing method 0.0 85541 1604
Crl:CD(SD) body weight standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. body mass male 168.0 days 8 440.0 g 9.19 26.0 body weighing method 0.0 85553 1604
Crl:CD(SD) plasma acetaminophen level standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 0.6 ug/ml 0.21 0.6 high-performance liquid chromatography 0.0 acetaminophen dosing 1140 min 19 hr after dosing 85584 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 168.0 days 8 4.34 g/d/100g 0.34 0.96 unspecified method 0.0 on days 95-98 85517 1604
Crl:CD(SD) food intake weight to body weight ratio standard diet then acetaminophen (500 mg/kg) (for 98 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. eating behavior trait male 168.0 days 8 4.24 g/d/100g 0.06 0.18 unspecified method 0.0 on days 95-98 85514 1604
Crl:CD(SD) liver reduced glutathione level to liver weight ratio standard diet then acetaminophen (500 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver glutathione amount male 170.0 days 8 9.07 umol/g 0.25 0.72 reduced glutathione/oxidized glutathione enzyme recycling assay 0.0 enzyme recycling method reduced liver glutathione level to liver weight ratio 85568 1604
Crl:CD(SD) plasma acetaminophen level standard diet then acetaminophen (300 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 0.3 ug/ml 0.18 0.5 high-performance liquid chromatography 0.0 acetaminophen dosing 1140 min 19 hr after dosing 85582 1604
Crl:CD(SD) plasma acetaminophen level standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 64.3 ug/ml 9.72 27.5 high-performance liquid chromatography 0.0 acetaminophen dosing 240 min 4 hr after dosing 85581 1604
Crl:CD(SD) plasma acetaminophen level standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. blood acetaminophen amount male 170.0 days 8 49.3 ug/ml 5.62 15.9 high-performance liquid chromatography 0.0 acetaminophen dosing 240 min 4 hr after dosing 85580 1604
Crl:CD(SD) liver oxidized glutathione level to liver weight ratio standard diet then acetaminophen (300 mg/kg) (for 99 days) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver glutathione amount male 170.0 days 8 0.24 umol/g 0.01 0.02 reduced glutathione/oxidized glutathione enzyme recycling assay 0.0 enzyme recycling method reduced liver glutathione level to liver weight ratio 85573 1604
Crl:CD(SD) liver oxidized glutathione level to liver weight ratio standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) then fasting (for 20 hours) Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. liver glutathione amount male 170.0 days 8 0.14 umol/g 0.0 0.01 reduced glutathione/oxidized glutathione enzyme recycling assay 0.0 enzyme recycling method 85577 1604