| SD |
glomerular filtration rate to body weight ratio |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
days
| 8 |
0.67 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
stz |
154 |
days |
99902 |
2358 |
| SD |
glomerular filtration rate to body weight ratio |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
days
| 8 |
0.65 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
stz |
224 |
days |
99927 |
2358 |
| WKY |
glomerular filtration rate to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
glomerular filtration trait |
male |
days
| 17 |
0.69 |
ml/min/100g |
0.03 |
0.13 |
inulin analysis by liquid phase colorimetry |
0.0 |
unx |
168 |
days |
99982 |
2378 |
| SD |
glomerular filtration rate to body weight ratio |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
days
| 8 |
0.67 |
ml/min/100g |
0.03 |
0.08 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
stz |
224 |
days |
99926 |
2358 |
| WKY |
glomerular filtration rate to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
glomerular filtration trait |
male |
days
| 8 |
0.79 |
ml/min/100g |
0.03 |
0.08 |
inulin analysis by liquid phase colorimetry |
0.0 |
unx |
28 |
days |
99946 |
2378 |
| WKY |
glomerular filtration rate to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
glomerular filtration trait |
male |
days
| 8 |
0.52 |
ml/min/100g |
0.03 |
0.07 |
inulin analysis by liquid phase colorimetry |
0.0 |
unx |
28 |
days |
99947 |
2378 |
| SD |
glomerular filtration rate to body weight ratio |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
days
| 8 |
0.68 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
stz |
154 |
days |
99903 |
2358 |
| WKY |
glomerular filtration rate to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
glomerular filtration trait |
male |
days
| 16 |
0.66 |
ml/min/100g |
0.02 |
0.09 |
inulin analysis by liquid phase colorimetry |
0.0 |
unx |
168 |
days |
99983 |
2378 |
| WKY |
glomerular filtration rate to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
glomerular filtration trait |
male |
days
| 16 |
0.67 |
ml/min/100g |
0.02 |
0.08 |
inulin analysis by liquid phase colorimetry |
0.0 |
unx |
168 |
days |
99984 |
2378 |
| WKY |
glomerular filtration rate to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
glomerular filtration trait |
male |
days
| 17 |
0.5 |
ml/min/100g |
0.03 |
0.12 |
inulin analysis by liquid phase colorimetry |
0.0 |
unx |
168 |
days |
99981 |
2378 |
| WKY |
glomerular filtration rate to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
glomerular filtration trait |
male |
days
| 8 |
0.54 |
ml/min/100g |
0.02 |
0.05 |
inulin analysis by liquid phase colorimetry |
0.0 |
unx |
28 |
days |
99948 |
2378 |
| WKY |
glomerular filtration rate to body weight ratio |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
glomerular filtration trait |
male |
days
| 6 |
0.5 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by liquid phase colorimetry |
0.0 |
unx |
28 |
days |
99949 |
2378 |