| DA.ACI-(D10Rat15-D10Rat29) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
62.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67855 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
10 |
40.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67856 |
829 |
| DA.ACI-(D10Rat2-D10Rat6) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
100.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67860 |
829 |
| DA.ACI-(D10Rat2-D10Rat6) |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
87.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68207 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
37.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68204 |
829 |
| DA.ACI-(D10Rat10-D10Rat142) |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
6 |
13.5 |
d |
3.1 |
7.59 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68218 |
829 |
| DA.ACI-(D10Rat10-D10Rat142) |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
7 |
71.4 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68219 |
829 |
| DA/ZtmKini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103.0 days-131.0 days |
12 |
1.0 |
% |
0.78 |
2.7 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
68712 |
839 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
12 |
50.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68710 |
839 |
| DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
8 |
87.5 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68717 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
3 |
0.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68721 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103.0 days-131.0 days |
8 |
0.0 |
% |
0.0 |
0.0 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
68725 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
37.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68732 |
829 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
7 |
0.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68733 |
829 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
7 |
14.3 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68734 |
829 |
| DA.PVG.1AV1-(D4Got60-D4Kini1)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 24 |
33.0 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to38 days |
|
69382 |
892 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 16 |
50.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
69384 |
892 |
| DA.PVG.1AV1-(D4Got211-D4Mit12)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 16 |
33.9 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 40 days |
|
69388 |
892 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 18 |
94.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
38 |
days |
from 8 to 38 days |
|
69390 |
892 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 18 |
20.9 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
38 |
days |
from 8 to 38 days |
days |
69393 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Rat108)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 31 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 10 |
22.6 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
31 |
days |
from 8 to 31days |
days |
69396 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Rat108)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 7 |
16.3 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 40 days |
|
69413 |
892 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 10 |
14.1 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 40 days |
|
69410 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Rat108)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 7 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
69412 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Mit12)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 14 |
18.4 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
69417 |
892 |
| DA.PVG.1AV1-(D4Rat231-D4Mit12)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 14 |
28.9 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 34 days |
|
69433 |
892 |
| DA.ACI-(D10Rat219-D10Rat29) |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
13 |
7.4 |
d |
1.2 |
4.33 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68230 |
829 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103.0 days-131.0 days |
7 |
0.0 |
% |
0.0 |
0.0 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
68728 |
839 |
| DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65.0 days-112.0 days |
21 |
11.7 |
d |
2.23 |
10.2 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69490 |
837 |
| DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
91.0 days-112.0 days |
21 |
76.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
|
|
visual observation |
|
69488 |
837 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65.0 days-112.0 days |
22 |
15.8 |
d |
1.9 |
8.9 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69489 |
837 |
| DA.PVG.1AV1-(D4Got126-D4Got136) |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
total life span |
both |
63.0 days-150.0 days |
19 |
0.0 |
% |
|
|
necropsy |
|
0.0 |
intradermal injection |
|
|
visual observation |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time (CMO:0003802) |
68127 |
838 |
| DA.PVG.1AV1-(D4Got126-D4Got136) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
central nervous system integrity trait |
both |
63.0 days-150.0 days |
21 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
DA.PVG.1AV1-(D4Got128-D4Got136) for strain |
68130 |
838 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65.0 days-112.0 days |
12 |
19.7 |
d |
2.48 |
8.6 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69376 |
837 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
10 |
80.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67849 |
829 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
100.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67850 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
12 |
3.5 |
d |
1.7 |
5.89 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68194 |
829 |
| DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
87.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68201 |
829 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
14 |
13.4 |
d |
2.2 |
8.23 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68209 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
10 |
30.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68213 |
829 |
| DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
8 |
87.5 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68709 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
3 |
14.7 |
d |
1.44 |
2.5 |
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
|
68719 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103.0 days-131.0 days |
10 |
0.0 |
% |
0.0 |
0.0 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
68723 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
10 |
30.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68718 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
10 |
0.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68722 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
7 |
14.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68726 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
1 |
23.0 |
d |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
|
68727 |
839 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 16 |
33.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 40 days |
|
69385 |
892 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 37 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 28 |
10.7 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
37 |
days |
from 8 to 37 days |
days |
69381 |
892 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 16 |
6.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
days |
69386 |
892 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 10 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
69409 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Mit12)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 14 |
11.2 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 40 days |
|
69416 |
892 |
| DA.PVG.1AV1-(D4Rat103-D4Mit12)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 28 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 19 |
17.3 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 28 days |
|
69420 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Rat108)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 10 |
32.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 34 days |
|
69427 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Rat108)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 10 |
30.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
34 |
days |
from 8 to 34 days |
|
69426 |
892 |
| DA.PVG.1AV1-(D4Rat103-D4Mit12)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 9 |
5.9 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
34 |
days |
from 8 to 34 days |
|
69432 |
892 |
| DA.PVG.1AV1-(D4Rat231-D4Mit12)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 14 |
7.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
34 |
days |
from 8 to 34 days |
|
69434 |
892 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
14 |
18.5 |
d |
1.6 |
5.99 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68224 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
13 |
30.8 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
relap, % |
68228 |
829 |
| DA.ACI-(D10Rat219-D10Rat29) |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
16 |
25.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
expressed as a fraction of total number of animals |
68231 |
829 |
| DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (15-22 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91.0 days-112.0 days |
13 |
69.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
68123 |
837 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
1 |
0.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68729 |
839 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65.0 days-112.0 days |
22 |
19.6 |
d |
2.22 |
10.4 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69493 |
837 |
| DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65.0 days-112.0 days |
21 |
21.9 |
d |
2.47 |
11.3 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69494 |
837 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (0.09 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91.0 days-112.0 days |
|
89.0 |
% |
|
33.0 |
in vivo visual assessment |
|
0.0 |
|
|
|
visual observation |
|
69497 |
837 |
| DA.ACI-(D10Rat219-D10Rat29) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
16 |
81.2 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67874 |
829 |
| DA.ACI-(D10Rat12-D10Rat144) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
13 |
53.8 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67876 |
829 |
| DA/ZtmKini |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
total life span |
both |
63.0 days-150.0 days |
20 |
0.0 |
% |
|
|
necropsy |
|
0.0 |
intradermal injection |
|
|
visual observation |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time (CMO:0003802) |
68125 |
838 |
| N:HS |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (50-120 ug) and Freund's complete adjuvant (100 ul) |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
central nervous system integrity trait |
both |
132.0 days-177.0 days |
217 |
41.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
66040 |
114 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
16 |
87.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67852 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
12 |
8.3 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68195 |
829 |
| DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
10 |
70.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68198 |
829 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
16.4 |
d |
2.6 |
7.35 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68200 |
829 |
| DA.ACI-(D10Rat2-D10Rat6) |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
18.9 |
d |
2.2 |
6.22 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68206 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
4 |
8.7 |
d |
2.8 |
5.6 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68212 |
829 |
| DA.ACI-(D10Rat219-D10Rat29) |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
10 |
40.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68216 |
829 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
10 |
80.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68714 |
839 |
| DA/ZtmKini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103.0 days-131.0 days |
10 |
2.8 |
% |
1.26 |
4.0 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
68716 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
8 |
0.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68724 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
75.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68735 |
829 |
| ACI/SegHsd |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (0.25 mg/ml) and Freund's incomplete adjuvant (50 %) |
Dahlman I, et al., Hum Mol Genet 1999 Nov;8(12):2183-90. |
central nervous system integrity trait |
not specified |
70.0 days-145.0 days |
21 |
5.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69970 |
1279 |
| DA.PVG.1AV1-(D4Got60-D4Kini1)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 24 |
5.5 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
37 |
days |
from 8 to38 days |
days |
69383 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Rat108)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 31 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 10 |
18.2 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 31days |
|
69395 |
892 |
| DA.PVG.1AV1-(D4Got60-D4Kini1)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 11 |
17.4 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 38days |
|
69407 |
892 |
| DA.PVG.1AV1-(D4Got60-D4Kini1)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 11 |
91.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
38 |
days |
from 8 to 38days |
|
69406 |
892 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 10 |
23.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
69411 |
892 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 28 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 21 |
11.5 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
28 |
days |
from 8 to 28 days |
|
69419 |
892 |
| DA.PVG.1AV1-(D4Rat231-D4Mit12)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 28 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 21 |
16.2 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 28 days |
|
69422 |
892 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 17 |
9.0 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
34 |
days |
from 8 to 34 days |
|
69425 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Mit12)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 18 |
6.0 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
34 |
days |
from 8 to 34 days |
|
69430 |
892 |
| DA.PVG.1AV1-(D4Got60-D4Kini1)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 6 |
7.5 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
34 |
days |
from 8 to 34 days |
|
69437 |
892 |
| DA.ACI-(D10Rat12-D10Rat144) |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
13 |
38.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
relap, % |
68222 |
829 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
91.0 days-112.0 days |
22 |
82.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
|
|
visual observation |
|
69487 |
837 |
| DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (0.1 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65.0 days-112.0 days |
|
10.1 |
d |
|
9.5 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69502 |
837 |
| DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (0.1 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91.0 days-112.0 days |
|
69.0 |
% |
|
48.0 |
in vivo visual assessment |
|
0.0 |
|
|
|
visual observation |
|
69498 |
837 |
| DA.PVG.1AV1-(D4Got126-D4Got136) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
central nervous system integrity trait |
both |
63.0 days-150.0 days |
19 |
10.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
DA.PVG.1AV1-(D4Got128-D4Got136) for strain |
68126 |
838 |
| DA/ZtmKini |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
total life span |
both |
63.0 days-150.0 days |
23 |
61.0 |
% |
|
|
necropsy |
|
0.0 |
intradermal injection |
|
|
visual observation |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time (CMO:0003802) |
68129 |
838 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
central nervous system integrity trait |
both |
63.0 days-150.0 days |
23 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
|
68128 |
838 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
16 |
87.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67853 |
829 |
| DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
16 |
56.3 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68210 |
829 |
| DA.ACI-(D10Rat219-D10Rat29) |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
6 |
11.5 |
d |
2.6 |
6.37 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68215 |
829 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
11 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68132 |
839 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
8 |
16.2 |
d |
0.92 |
2.6 |
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
|
68707 |
839 |
| DA/ZtmKini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103.0 days-131.0 days |
10 |
3.5 |
% |
1.49 |
4.7 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
68708 |
839 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
10 |
80.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
68706 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103.0 days-131.0 days |
10 |
1.2 |
% |
1.14 |
3.6 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
68720 |
839 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
1 |
3.0 |
d |
0.0 |
0.0 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68730 |
829 |
| DA.ACI-(D10Rat2-D10Rat29)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
6 |
13.3 |
d |
2.6 |
6.37 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68731 |
829 |
| DA/Ztm |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (0.25 mg/ml) and Freund's incomplete adjuvant (50 %) |
Dahlman I, et al., Hum Mol Genet 1999 Nov;8(12):2183-90. |
central nervous system integrity trait |
not specified |
70.0 days-145.0 days |
36 |
72.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69969 |
1279 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 37 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 28 |
64.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
37 |
days |
from 8 to 37 days |
|
69378 |
892 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 37 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 28 |
26.5 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 37 days |
|
69380 |
892 |
| DA.PVG.1AV1-(D4Got60-D4Kini1)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 24 |
33.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
37 |
days |
from 8 to38 days |
|
69379 |
892 |
| DA.PVG.1AV1-(D4Got211-D4Mit12)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 31 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 19 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
31 |
days |
from 8 to 31days |
|
69397 |
892 |
| DA.PVG.1AV1-(D4Got211-D4Mit12)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 31 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 19 |
11.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
31 |
days |
from 8 to 31days |
days |
69399 |
892 |
| DA.PVG.1AV1-(D4Got60-D4Kini1)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 11 |
17.6 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
38 |
days |
from 8 to 38days |
|
69408 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Rat108)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 7 |
22.4 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
69414 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Mit12)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 14 |
86.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
69415 |
892 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 17 |
25.2 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 34 days |
|
69424 |
892 |
| DA.PVG.1AV1-(D4Rat231-D4Mit12)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 28 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 21 |
13.3 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
28 |
days |
from 8 to 28 days |
|
69423 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Mit12)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 18 |
31.2 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 34 days |
|
69429 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Rat108)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 10 |
2.7 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
34 |
days |
from 8 to 34 days |
|
69428 |
892 |
| DA.PVG.1AV1-(D4Got60-D4Kini1)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 6 |
28.3 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 34 days |
|
69436 |
892 |
| DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
16 |
81.3 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68225 |
829 |
| DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65.0 days-112.0 days |
13 |
22.5 |
d |
3.58 |
12.9 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69492 |
837 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65.0 days-112.0 days |
12 |
14.8 |
d |
2.4 |
8.3 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69491 |
837 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (0.09 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65.0 days-112.0 days |
|
15.6 |
d |
|
9.4 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69499 |
837 |
| DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (0.1 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65.0 days-112.0 days |
|
22.5 |
d |
|
12.9 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69500 |
837 |
| DA.ACI-(D10Rat10-D10Rat142) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
7 |
85.7 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67875 |
829 |
| DA.PVG.1AV1-(D4Got126-D4Got136) |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
total life span |
both |
63.0 days-150.0 days |
21 |
24.0 |
% |
|
|
necropsy |
|
0.0 |
intradermal injection |
|
|
visual observation |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time (CMO:0003802) |
68131 |
838 |
| DA.ACI-(D10Rat15-D10Rat29) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
12 |
33.3 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67848 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
13 |
76.9 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67859 |
829 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
8 |
13.0 |
d |
1.8 |
5.09 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68197 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
5 |
13.4 |
d |
2.0 |
4.47 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68203 |
829 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
11 |
14.9 |
d |
1.03 |
3.4 |
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
|
68133 |
839 |
| DA/ZtmKini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103.0 days-131.0 days |
11 |
14.4 |
% |
2.47 |
8.2 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
CMO:0001400 |
68134 |
839 |
| DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
11 |
91.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
CMO:0001402 |
68135 |
839 |
| DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
6 |
50.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
CMO:0001402 |
68713 |
839 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
6 |
21.2 |
d |
0.53 |
1.3 |
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
|
68711 |
839 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103.0 days-131.0 days |
8 |
19.2 |
d |
1.24 |
3.5 |
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
|
68715 |
839 |
| DA.PVG.1AV1-(D4Got211-D4Mit12)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 16 |
38.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
69387 |
892 |
| DA.PVG.1AV1-(D4Got211-D4Mit12)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 16 |
4.9 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
days |
69389 |
892 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 31 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 18 |
14.3 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
31 |
days |
from 8 to 31 days |
days |
69392 |
892 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 18 |
16.7 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 38 days |
|
69391 |
892 |
| DA.PVG.1AV1-(D4Rat23-D4Rat108)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 31 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 10 |
90.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
31 |
days |
from 8 to 31days |
|
69394 |
892 |
| DA.PVG.1AV1-(D4Got211-D4Mit12)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 31 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 19 |
15.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 31days |
days |
69398 |
892 |
| DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 28 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 21 |
18.7 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 28 days |
|
69418 |
892 |
| DA.PVG.1AV1-(D4Rat103-D4Mit12)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 28 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 19 |
11.2 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
28 |
days |
from 8 to 28 days |
|
69421 |
892 |
| DA.PVG.1AV1-(D4Rat103-D4Mit12)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 9 |
28.4 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
|
|
from 8 to 34 days |
|
69431 |
892 |
| DA.PVG.1AV1-(D4Got60-D4Kini1)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
days
| 6 |
50.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
34 |
days |
from 8 to 34 days |
|
69435 |
892 |
| DA.ACI-(D10Rat12-D10Rat144) |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
7 |
14.4 |
d |
2.8 |
7.41 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68221 |
829 |
| DA.ACI-(D10Rat15-D10Rat29) |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
10 |
8.6 |
d |
1.5 |
4.74 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
68227 |
829 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (15-22 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91.0 days-112.0 days |
12 |
92.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
68122 |
837 |
| DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (0.09 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65.0 days-112.0 days |
|
20.0 |
d |
|
8.5 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69501 |
837 |
| DA.ACI-(D10Rat219-D10Rat29) |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63.0 days-105.0 days |
10 |
60.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
67873 |
829 |
| DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
central nervous system integrity trait |
both |
63.0 days-150.0 days |
20 |
60.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
|
|
from p.i. day 7 |
|
68124 |
838 |
| DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65.0 days-112.0 days |
13 |
10.1 |
d |
2.63 |
9.5 |
in vivo visual assessment |
|
0.0 |
|
|
|
|
|
69377 |
837 |