Phenominer Database Results (39 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
SS/JrHsdMcwi ratio of change in renal blood flow rate to kidney weight controlled sodium content diet (0.4 %) (for 16 hours) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renal blood flow trait female 97.0 days-101.0 days 13 -2.4 ml/min/g 0.5 1.8 electromagnetic flowmetry 0.0 electromagnetic flowmetry 67306 151
SS/JrHsdMcwi resting tone of middle cerebral artery angiotensin II (3 ng/kg/min) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) then NG-nitroarginine methyl ester (100 umol/l) (for 0.3 hours) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63.0 days-98.0 days 5 [(Dmax - Drest) /Dmax] x 100 54.0 % 2.2 4.92 ex vivo videomicroscopy 0.0 69578 732
SS/JrHsdMcwi tibialis anterior muscle weight to body weight ratio control condition (for 7 days) then angiotensin II (3 ng/kg/min) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. skeletal muscle mass male 56.0 days-70.0 days 4 TA/BW 1.68 mg/g 0.04 0.08 ex vivo method 0.0 TA or EDL muscle weight body weight ratio 99051 2198
SS/JrHsdMcwi extensor digitorum longus muscle weight to body weight ratio control condition (for 7 days) then angiotensin II (3 ng/kg/min) (for 7 days) then controlled losartan content drinking water (50 mg/kg/d) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. skeletal muscle mass male 56.0 days-70.0 days 3 EDL/BW 0.43 mg/g 0.01 0.02 ex vivo method 0.0 TA or EDL muscle weight body weight ratio 99053 2198
SS/JrHsdMcwi tibialis anterior muscle weight to body weight ratio common peroneal nerve direct electrical stimulation (3 V) (for 8 hours) then angiotensin II (3 ng/kg/min) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. skeletal muscle mass male 56.0 days-70.0 days 4 TA/BW 1.74 mg/g 0.08 0.16 ex vivo method 0.0 TA or EDL muscle weight body weight ratio 99052 2198
SS/JrHsdMcwi tibialis anterior muscle weight to body weight ratio common peroneal nerve direct electrical stimulation (3 V) (for 8 hours) then angiotensin II (3 ng/kg/min) (for 7 days) then controlled losartan content drinking water (50 mg/kg/d) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. skeletal muscle mass male 56.0 days-70.0 days 3 TA/BW 1.88 mg/g 0.04 0.07 ex vivo method 0.0 TA or EDL muscle weight body weight ratio 99056 2198
SS/JrHsdMcwi heart left ventricle end-diastolic anterior wall thickness angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle anterior wall thickness male 63.0 days-70.0 days 5 2.19 mm 0.21 0.47 transthoracic echocardiography 0.0 105810 3023
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (20 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 131.3 mmHg 4.2 15.14 vascular indwelling catheter method left femoral artery 120.0 69530 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 160.2 mmHg 3.5 12.62 vascular indwelling catheter method left femoral artery 120.0 69534 151
SS/JrHsdMcwi heart left ventricle end-diastolic anterior wall thickness angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle anterior wall thickness male 77.0 days-84.0 days 5 2.13 mm 0.09 0.2 transthoracic echocardiography 0.0 105812 3023
SS/JrHsdMcwi heart left ventricle end-diastolic posterior wall thickness angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle posterior wall thickness male 63.0 days-70.0 days 5 2.17 mm 0.11 0.25 transthoracic echocardiography 0.0 105816 3023
SS/JrHsdMcwi heart left ventricle end-diastolic diameter angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 63.0 days-70.0 days 5 6.63 mm 0.37 0.83 transthoracic echocardiography 0.0 should be inner diameter 105822 3023
SS/JrHsdMcwi heart rate angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart pumping trait male 63.0 days-70.0 days 5 394.0 beats/min 6.0 13.42 transthoracic echocardiography 0.0 105834 3023
SS/JrHsdMcwi cardiac output angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. cardiac output trait male 63.0 days-70.0 days 5 78.0 ml/min 10.0 22.36 transthoracic echocardiography 0.0 105846 3023
SS/JrHsdMcwi lung weight to tibia length ratio angiotensin II (200 ng/kg/min) (for 28 days) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. lung mass male 77.0 days-84.0 days 6 0.28 g/cm 0.01 0.02 post excision weight measurement 0.0 105854 3023
SS/JrHsdMcwi single kidney weight to tibia length ratio angiotensin II (200 ng/kg/min) (for 28 days) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. kidney mass male 77.0 days-84.0 days 6 0.28 g/cm 0.01 0.02 post excision weight measurement 0.0 105852 3023
SS/JrHsdMcwi tibialis anterior muscle weight to body weight ratio control condition (for 7 days) then angiotensin II (3 ng/kg/min) (for 7 days) then controlled losartan content drinking water (50 mg/kg/d) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. skeletal muscle mass male 56.0 days-70.0 days 3 TA/BW 1.77 mg/g 0.05 0.09 ex vivo method 0.0 TA or EDL muscle weight body weight ratio 99055 2198
SS/JrHsdMcwi middle cerebral artery inner diameter angiotensin II (3 ng/kg/min) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63.0 days-98.0 days 5 247.0 um 7.8 17.44 ex vivo videomicroscopy 0.0 69574 732
SS/JrHsdMcwi middle cerebral artery inner diameter angiotensin II (3 ng/kg/min) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) then NG-nitroarginine methyl ester (100 umol/l) (for 0.3 hours) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63.0 days-98.0 days 5 246.0 um 3.7 8.27 ex vivo videomicroscopy 0.0 69577 732
SS/JrHsdMcwi body weight common peroneal nerve direct electrical stimulation (3 V) (for 8 hours) then angiotensin II (3 ng/kg/min) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. body mass male 56.0 days-70.0 days 4 270.8 g 7.8 15.6 body weighing method 0.0 99014 2198
SS/JrHsdMcwi body weight common peroneal nerve direct electrical stimulation (3 V) (for 8 hours) then angiotensin II (3 ng/kg/min) (for 7 days) then controlled losartan content drinking water (50 mg/kg/d) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. body mass male 56.0 days-70.0 days 3 282.8 g 2.9 5.02 body weighing method 0.0 99016 2198
SS/JrHsdMcwi extensor digitorum longus muscle weight to body weight ratio control condition (for 7 days) then angiotensin II (3 ng/kg/min) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. skeletal muscle mass male 56.0 days-70.0 days 4 EDL/BW 0.4 mg/g 0.02 0.04 ex vivo method 0.0 TA or EDL muscle weight body weight ratio 99049 2198
SS/JrHsdMcwi heart left ventricle fractional shortening angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 63.0 days-70.0 days 5 57.2 % 2.7 6.04 transthoracic echocardiography 0.0 105828 3023
SS/JrHsdMcwi stroke volume angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. blood flow trait male 63.0 days-70.0 days 5 0.2 ml 0.03 0.06 transthoracic echocardiography 0.0 105840 3023
SS/JrHsdMcwi middle cerebral artery inner diameter angiotensin II (3 ng/kg/min) (for 3 days) then physiological salt solution perfusate Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63.0 days-98.0 days 6 157.0 um 2.0 4.9 ex vivo videomicroscopy 0.0 69573 732
SS/JrHsdMcwi resting tone of middle cerebral artery angiotensin II (3 ng/kg/min) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63.0 days-98.0 days 5 [(Dmax - Drest) /Dmax] x 100 37.0 % 1.5 3.35 ex vivo videomicroscopy 0.0 69575 732
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (100 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 147.2 mmHg 3.9 14.06 vascular indwelling catheter method left femoral artery 120.0 69532 151
SS/JrHsdMcwi extensor digitorum longus muscle weight to body weight ratio common peroneal nerve direct electrical stimulation (3 V) (for 8 hours) then angiotensin II (3 ng/kg/min) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. skeletal muscle mass male 56.0 days-70.0 days 4 EDL/BW 0.41 mg/g 0.02 0.04 ex vivo method 0.0 TA or EDL muscle weight body weight ratio 99050 2198
SS/JrHsdMcwi extensor digitorum longus muscle weight to body weight ratio common peroneal nerve direct electrical stimulation (3 V) (for 8 hours) then angiotensin II (3 ng/kg/min) (for 7 days) then controlled losartan content drinking water (50 mg/kg/d) (for 7 days) Stodola TJ, et al., Physiol Genomics. 2011 Jul 14;43(13):808-17. doi: 10.1152/physiolgenomics.00171.2010. Epub 2011 Apr 26. skeletal muscle mass male 56.0 days-70.0 days 3 EDL/BW 0.46 mg/g 0.01 0.02 ex vivo method 0.0 TA or EDL muscle weight body weight ratio 99054 2198
SS/JrHsdMcwi heart left ventricle end-diastolic posterior wall thickness angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle posterior wall thickness male 77.0 days-84.0 days 5 1.94 mm 0.18 0.4 transthoracic echocardiography 0.0 105818 3023
SS/JrHsdMcwi heart left ventricle end-diastolic diameter angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 77.0 days-84.0 days 5 7.15 mm 0.34 0.76 transthoracic echocardiography 0.0 should be inner diameter 105824 3023
SS/JrHsdMcwi cardiac output angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. cardiac output trait male 77.0 days-84.0 days 5 77.0 ml/min 6.0 13.42 transthoracic echocardiography 0.0 105848 3023
SS/JrHsdMcwi absolute change in mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 34.0 mmHg 3.0 10.82 vascular indwelling catheter method left femoral artery 0.0 67300 151
SS/JrHsdMcwi middle cerebral artery inner diameter angiotensin II (3 ng/kg/min) (for 3 days) then physiological salt solution perfusate then NG-nitroarginine methyl ester (100 umol/l) (for 0.3 hours) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63.0 days-98.0 days 5 113.0 um 4.2 9.39 ex vivo videomicroscopy 0.0 69576 732
SS/JrHsdMcwi heart left ventricle fractional shortening angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 77.0 days-84.0 days 5 51.9 % 3.7 8.27 transthoracic echocardiography 0.0 105830 3023
SS/JrHsdMcwi heart rate angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart pumping trait male 77.0 days-84.0 days 5 358.0 beats/min 17.0 38.01 transthoracic echocardiography 0.0 105836 3023
SS/JrHsdMcwi stroke volume angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. blood flow trait male 77.0 days-84.0 days 5 0.22 ml 0.02 0.05 transthoracic echocardiography 0.0 105842 3023
SS/JrHsdMcwi heart left ventricle weight to tibia length ratio angiotensin II (200 ng/kg/min) (for 28 days) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle mass male 77.0 days-84.0 days 6 0.19 g/cm 0.01 0.02 post excision weight measurement 0.0 105850 3023
SS/JrHsdMcwi tibia length angiotensin II (200 ng/kg/min) (for 28 days) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. tibia length male 77.0 days-84.0 days 6 3.96 cm 0.03 0.07 post excision length measurement 0.0 105856 3023