Phenominer Database Results (12 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
Hsd:SD acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 14 85.5 % 4.86 18.18 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 55731 522
Hsd:SD concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 10 2.97 E-7mole 0.71 2.23 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 56211 522
Hsd:SD concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 19 0.83 E-7mole 0.17 0.76 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 56726 522
Hsd:SD logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 10 -6.62 null 0.09 0.29 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 57193 522
Hsd:SD concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 14 1.29 E-7mole 0.19 0.72 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 56725 522
Hsd:SD acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 19 84.63 % 3.67 16.01 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 56807 522
Hsd:SD logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 14 -6.98 null 0.11 0.4 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 57194 522
Hsd:SD acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 10 69.0 % 6.69 21.17 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 55730 522
Hsd:SD acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 14 82.29 % 3.52 13.16 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 56806 522
Hsd:SD logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 14 -6.95 null 0.07 0.25 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 56225 522
Hsd:SD concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 14 1.7 E-7mole 0.61 2.3 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 56212 522
Hsd:SD logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 19 -7.19 null 0.07 0.3 wire myography using a Digi-Med tissue force analysis system with force transducer Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 56226 522