| LE/BluGill |
methylene blue metabolism-surface area product after auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
14 |
10.88 |
ml/min/kg |
1.17 |
4.39 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57454 |
526 |
| LE/BluGill |
methylene blue metabolism-surface area product without auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
13 |
11.53 |
ml/min/kg |
0.99 |
3.57 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58313 |
526 |
| LE/BluGill |
methylene blue to FAPGG metabolism-surface area product ratio |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
14 |
0.42 |
null |
0.01 |
0.05 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58581 |
526 |
| LE/BluGill |
methylene blue metabolism-surface area product without auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
14 |
13.93 |
ml/min/kg |
0.89 |
3.35 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58843 |
526 |
| LE/BluGill |
methylene blue metabolism-surface area product after auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
13 |
12.13 |
ml/min/kg |
0.52 |
1.88 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
59865 |
526 |
| LE/BluGill |
methylene blue metabolism-surface area product without auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
14 |
14.81 |
ml/min/kg |
1.73 |
6.46 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58309 |
526 |
| LE/BluGill |
methylene blue metabolism-surface area product after auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
13 |
9.11 |
ml/min/kg |
0.78 |
2.82 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57458 |
526 |
| LE/BluGill |
methylene blue to FAPGG metabolism-surface area product ratio |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
13 |
0.28 |
null |
0.02 |
0.08 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57742 |
526 |
| LE/BluGill |
methylene blue metabolism-surface area product without auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
13 |
17.95 |
ml/min/kg |
0.91 |
3.28 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58839 |
526 |
| LE/BluGill |
methylene blue to FAPGG metabolism-surface area product ratio |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
14 |
0.33 |
null |
0.03 |
0.12 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57738 |
526 |
| LE/BluGill |
methylene blue to FAPGG metabolism-surface area product ratio |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
13 |
0.45 |
null |
0.02 |
0.05 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58577 |
526 |
| LE/BluGill |
methylene blue metabolism-surface area product after auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
14 |
10.23 |
ml/min/kg |
0.79 |
2.97 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
59869 |
526 |