Phenominer Database Results (227 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Experiment Notes Record ID Study ID
GH/OmrMcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 8 0.34 ml 0.02 0.06 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14621 381
GH/OmrMcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 7 101.0 % 3.6 9.53 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53877 381
GH/OmrMcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 7 102.95 % 5.97 15.8 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53978 381
GH/OmrMcwi blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait female 82.0 days-99.0 days 3 7.51 null 0.02 0.03 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17037 381
GH/OmrMcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 6 118.06 breaths/min 10.4 25.47 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 18315 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 463.94 beats/min 7.82 20.68 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18757 381
GH/OmrMcwi absolute change in blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait female 82.0 days-99.0 days 7 0.06 null 0.01 0.02 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18787 381
GH/OmrMcwi serum alkaline phosphatase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount male 77.0 days-91.0 days 18 360.72 U/l 5.19 22.0 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36428 401
GH/OmrMcwi serum total cholesterol level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount male 77.0 days-91.0 days 18 78.89 mg/dl 2.0 8.48 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37146 401
GH/OmrMcwi absolute change in partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount female 82.0 days-99.0 days 7 -46.56 mmHg 3.72 9.84 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18642 381
GH/OmrMcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 6 51.01 ml/min 8.13 19.91 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 18712 381
GH/OmrMcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 6 46.6 ml/min 8.6 21.07 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 20258 381
GH/OmrMcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82.0 days-99.0 days 6 -0.12 degrees C 0.37 0.91 digital rectal thermometry Moms and pups used in studies were fed Teklad 20359 381
GH/OmrMcwi partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount male 82.0 days-99.0 days 3 48.77 mmHg 2.36 4.08 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 20470 381
GH/OmrMcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 10 875.15 s 114.44 361.88 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49343 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 7 0.27 IU/g 0.04 0.11 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 49678 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 9 0.32 IU/g 0.04 0.13 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 49682 461
GH/OmrMcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 7 52.86 mmHg 4.36 11.54 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 49795 461
GH/OmrMcwi serum bicarbonate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount male 77.0 days-91.0 days 18 16.0 mmol/l 0.56 2.38 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42111 401
GH/OmrMcwi serum albumin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount female 77.0 days-91.0 days 16 4.03 g/dl 0.08 0.3 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42277 401
GH/OmrMcwi serum albumin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount male 77.0 days-91.0 days 18 3.96 g/dl 0.04 0.15 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42282 401
GH/OmrMcwi red blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77.0 days-91.0 days 12 9.91 x 10E6 cells/ul 0.22 0.77 automated blood cell counting method Moms and pups used in studies were fed Teklad 39281 401
GH/OmrMcwi mean corpuscular hemoglobin controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77.0 days-91.0 days 12 19.85 pg 0.35 1.23 automated blood cell counting method Moms and pups used in studies were fed Teklad 42589 401
GH/OmrMcwi serum sodium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount female 77.0 days-91.0 days 15 142.6 mmol/l 0.88 3.4 standard blood chemistry panel Moms and pups used in studies were fed Teklad 39432 401
GH/OmrMcwi blood monocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity female 77.0 days-91.0 days 12 0.16 x 1000 cells/ul 0.03 0.12 automated blood cell counting method Moms and pups used in studies were fed Teklad 39718 401
GH/OmrMcwi mean corpuscular hemoglobin concentration controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77.0 days-91.0 days 12 32.68 g/dl 0.18 0.63 automated blood cell counting method Moms and pups used in studies were fed Teklad 39821 401
GH/OmrMcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass male 77.0 days-91.0 days 34 205.0 g 4.5 26.4 whole body digital scale Moms and pups used in studies were fed Teklad 59111 526
GH/OmrMcwi serum globulin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount female 77.0 days-91.0 days 16 2.18 g/dl 0.11 0.45 standard blood chemistry panel replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40594 401
GH/OmrMcwi serum phosphate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount female 77.0 days-91.0 days 16 8.03 mg/dl 0.34 1.38 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37638 401
GH/OmrMcwi total white blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity male 77.0 days-91.0 days 16 4.98 x 1000 cells/ul 0.6 2.41 automated blood cell counting method Moms and pups used in studies were fed Teklad 40975 401
GH/OmrMcwi lung dry weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass male 77.0 days-91.0 days 34 1.15 g/kg 0.02 0.13 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 59706 526
GH/OmrMcwi blood hemoglobin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77.0 days-91.0 days 12 19.62 g/dl 0.37 1.29 automated blood cell counting method Moms and pups used in studies were fed Teklad 38012 401
GH/OmrMcwi plasma anion gap controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait female 77.0 days-91.0 days 15 24.6 mmol/l 0.54 2.1 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38305 401
GH/OmrMcwi serum total bilirubin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount female 77.0 days-91.0 days 16 0.18 mg/dl 0.02 0.09 standard blood chemistry panel Moms and pups used in studies were fed Teklad 41912 401
GH/OmrMcwi heart wet weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49.0 days-63.0 days 10 0.92 g 0.04 0.14 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 45449 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 209.85 beats/min 7.0 19.8 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47626 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 66.02 % 2.67 7.05 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48502 461
GH/OmrMcwi methylene blue to FAPGG metabolism-surface area product ratio controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 8 0.3 null 0.04 0.11 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 58162 526
GH/OmrMcwi dose of methacholine at which pulmonary conductance is half its pretreatment value controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait female 77.0 days-91.0 days 16 3.84 mg/kg 0.47 1.89 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 58950 526
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 79.44 mmHg 11.13 33.4 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45692 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 10 9.43 IU/g 1.35 4.27 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 45699 461
GH/OmrMcwi heart wet weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49.0 days-63.0 days 7 1.25 g 0.1 0.26 digital scale post excision weight measurement Moms and pups used in studies were fed Dyets 45829 461
GH/OmrMcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 75.14 % 3.84 11.51 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46038 461
GH/OmrMcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 8 152.48 breaths/min 5.93 16.77 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15583 381
GH/OmrMcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 8 0.37 ml 0.02 0.05 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14629 381
GH/OmrMcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 6 122.26 breaths/min 14.96 36.64 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 14844 381
GH/OmrMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 159.77 mmHg 3.14 6.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14319 381
GH/OmrMcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 6 %change=VE during 2-3 min hypoxia/control during standard conditions 138.49 % 7.54 18.47 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 13730 381
GH/OmrMcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 6 0.43 ml 0.06 0.14 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 13973 381
GH/OmrMcwi absolute change in blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait male 82.0 days-99.0 days 3 0.04 null 0.02 0.03 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19779 381
GH/OmrMcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 6 119.01 % 6.94 17.01 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53884 381
GH/OmrMcwi blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait male 82.0 days-99.0 days 7 7.52 null 0.0 0.01 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20120 381
GH/OmrMcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82.0 days-99.0 days 7 37.14 degrees C 0.16 0.43 digital rectal thermometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17725 381
GH/OmrMcwi blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait male 82.0 days-99.0 days 3 7.52 null 0.01 0.02 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17043 381
GH/OmrMcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 7 132.88 breaths/min 4.89 12.94 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 18310 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 416.79 beats/min 8.48 22.45 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18761 381
GH/OmrMcwi absolute change in partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount male 82.0 days-99.0 days 7 -47.66 mmHg 2.4 6.35 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18646 381
GH/OmrMcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 7 133.26 breaths/min 6.22 16.45 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18153 381
GH/OmrMcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass female 49.0 days-63.0 days 10 143.2 g 2.5 8.0 whole body digital scale Moms and pups used in studies were fed Teklad 49517 461
GH/OmrMcwi mean corpuscular hemoglobin controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77.0 days-91.0 days 16 19.88 pg 0.1 0.38 automated blood cell counting method Moms and pups used in studies were fed Teklad 42594 401
GH/OmrMcwi serum aspartate aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount male 77.0 days-91.0 days 18 122.67 U/l 11.17 47.4 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42819 401
GH/OmrMcwi plasma creatinine level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount female 77.0 days-91.0 days 16 0.34 mg/dl 0.02 0.08 automated plasma creatinine analysis Moms and pups used in studies were fed Teklad 39620 401
GH/OmrMcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 7 117.61 % 4.64 12.28 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 54307 381
GH/OmrMcwi blood neutrophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity male 77.0 days-91.0 days 16 1.0 x 1000 cells/ul 0.15 0.6 automated blood cell counting method Moms and pups used in studies were fed Teklad 43273 401
GH/OmrMcwi serum globulin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount male 77.0 days-91.0 days 18 2.26 g/dl 0.04 0.17 standard blood chemistry panel replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40599 401
GH/OmrMcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount female 77.0 days-91.0 days 14 4.79 mmol/l 0.11 0.41 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38110 401
GH/OmrMcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount male 77.0 days-91.0 days 15 4.87 mmol/l 0.17 0.64 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38115 401
GH/OmrMcwi serum total bilirubin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount male 77.0 days-91.0 days 18 0.2 mg/dl 0.02 0.1 standard blood chemistry panel Moms and pups used in studies were fed Teklad 41917 401
GH/OmrMcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 54.46 % 9.53 28.58 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 47519 461
GH/OmrMcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 6 post-ischemic value/pre-ischemic value x 100% 56.6 % 5.4 13.24 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 47515 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 5.0 mmHg 0.17 0.5 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 47539 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 post-ischemic value/pre-ischemic value x 100% 54.64 % 10.4 32.9 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48571 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 214.57 mmHg 18.48 48.9 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48734 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 144.29 mmHg 12.97 34.31 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48726 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 227.67 mmHg 6.56 19.67 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48738 461
GH/OmrMcwi methylene blue metabolism-surface area product without auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 20 10.9 ml/min/kg 0.86 3.82 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57849 526
GH/OmrMcwi FAPGG metabolism-surface area product controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 16 38.29 ml/min/kg 4.16 16.63 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 58043 526
GH/OmrMcwi FAPGG metabolism-surface area product controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 18 28.94 ml/min/kg 2.39 10.14 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 58048 526
GH/OmrMcwi methylene blue to FAPGG metabolism-surface area product ratio controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 8 0.27 null 0.02 0.04 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 58157 526
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 10 9.98 ml/min/g 2.16 6.83 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 44762 461
GH/OmrMcwi heart wet weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49.0 days-63.0 days 9 1.45 g 0.08 0.23 digital scale post excision weight measurement Moms and pups used in studies were fed Dyets 45833 461
GH/OmrMcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 53.44 % 5.49 14.52 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47121 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 232.67 mmHg 6.49 19.48 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45379 461
GH/OmrMcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82.0 days-99.0 days 8 -1.09 degrees C 0.28 0.78 digital rectal thermometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14133 381
GH/OmrMcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 6 123.82 % 16.01 39.21 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53752 381
GH/OmrMcwi percent change in ventilation controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 8 %change=VE during7-9 min hypoxia/control during standard conditions 142.36 % 11.33 32.05 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18371 381
GH/OmrMcwi percent change in ventilation controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 7 %change=VE during7-9 min hypoxia/control during standard conditions 141.15 % 6.17 16.32 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18375 381
GH/OmrMcwi partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount male 82.0 days-99.0 days 7 50.69 mmHg 0.76 2.0 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18979 381
GH/OmrMcwi serum total cholesterol level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount female 77.0 days-91.0 days 16 81.88 mg/dl 2.52 10.08 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37141 401
GH/OmrMcwi absolute change in partial pressure of blood carbon dioxide controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood carbon dioxide amount female 82.0 days-99.0 days 7 -7.83 mmHg 0.73 1.94 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19330 381
GH/OmrMcwi absolute change in partial pressure of blood carbon dioxide controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood carbon dioxide amount male 82.0 days-99.0 days 7 -5.0 mmHg 1.22 3.22 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19334 381
GH/OmrMcwi absolute change in partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount male 82.0 days-99.0 days 3 -38.88 mmHg 3.31 5.73 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19458 381
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 6 9.38 % 2.95 7.23 digital scale post excision weight measurement Moms and pups used in studies were fed Dyets 49630 461
GH/OmrMcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 9 48.78 mmHg 6.85 20.55 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 49799 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 135.34 mmHg 10.99 34.74 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49932 461
GH/OmrMcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 9 42.33 mmHg 5.6 16.81 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 50041 461
GH/OmrMcwi serum chloride level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount female 77.0 days-91.0 days 15 109.27 mmol/l 0.85 3.31 standard blood chemistry panel Moms and pups used in studies were fed Teklad 39161 401
GH/OmrMcwi red blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77.0 days-91.0 days 16 9.7 x 10E6 cells/ul 0.1 0.38 automated blood cell counting method Moms and pups used in studies were fed Teklad 39286 401
GH/OmrMcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 8 116.4 % 4.08 11.55 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 54303 381
GH/OmrMcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 6 119.17 % 10.79 26.43 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 54325 381
GH/OmrMcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 7 130.39 % 5.48 14.49 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 53539 381
GH/OmrMcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass female 77.0 days-91.0 days 35 159.3 g 2.5 14.6 whole body digital scale Moms and pups used in studies were fed Teklad 59106 526
GH/OmrMcwi serum alanine aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount male 77.0 days-91.0 days 18 69.17 U/l 3.66 15.53 standard blood chemistry panel Moms and pups used in studies were fed Teklad 40763 401
GH/OmrMcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity male 77.0 days-91.0 days 20 58.51 % 0.62 2.77 microhematocrit tube assay with visual assessment Moms and pups used in studies were fed Teklad 59306 526
GH/OmrMcwi calculated pulmonary vascular resistance normalized to body weight controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 30 0.17 mmHg x min x kg x ml-1 0.01 0.04 fluid-filled catheter with pressure transducer in isolated perfused lung Moms and pups used in studies were fed Teklad 59591 526
GH/OmrMcwi blood hemoglobin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77.0 days-91.0 days 16 19.28 g/dl 0.16 0.64 automated blood cell counting method Moms and pups used in studies were fed Teklad 38017 401
GH/OmrMcwi blood lymphocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity female 77.0 days-91.0 days 12 2.76 x 1000 cells/ul 0.38 1.31 automated blood cell counting method Moms and pups used in studies were fed Teklad 41547 401
GH/OmrMcwi blood lymphocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity male 77.0 days-91.0 days 16 3.77 x 1000 cells/ul 0.48 1.9 automated blood cell counting method Moms and pups used in studies were fed Teklad 41552 401
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 33.27 mmHg 6.92 21.88 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 46461 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 6 271.62 beats/min 13.53 33.14 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46514 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 post-ischemic value/pre-ischemic value x 100% 77.33 % 4.74 14.99 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48800 461
GH/OmrMcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82.0 days-99.0 days 6 37.28 degrees C 0.31 0.75 digital rectal thermometry Moms and pups used in studies were fed Teklad 16622 381
GH/OmrMcwi dose of methacholine at which pulmonary conductance is half its pretreatment value controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait male 77.0 days-91.0 days 14 2.59 mg/kg 0.68 2.55 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 58955 526
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 7 11.53 ml/min/g 1.28 3.4 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46697 461
GH/OmrMcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 69.1 % 5.05 13.36 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46034 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 57.56 mmHg 6.5 19.49 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45061 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 44.43 mmHg 6.05 16.0 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45057 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 6 10.33 ml/min/g 0.78 1.91 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 46287 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 10 0.37 IU/g 0.07 0.24 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47446 461
GH/OmrMcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 post-ischemic value/pre-ischemic value x 100% 71.22 % 11.09 31.37 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48339 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 189.11 beats/min 10.37 31.11 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45254 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 96.8 mmHg 18.68 59.07 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45314 461
GH/OmrMcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 7 0.35 ml 0.03 0.09 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 15278 381
GH/OmrMcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 6 0.38 ml 0.05 0.13 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 15283 381
GH/OmrMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 141.2 mmHg 6.68 17.68 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14413 381
GH/OmrMcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 7 0.4 ml 0.03 0.07 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14633 381
GH/OmrMcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 7 131.49 breaths/min 4.61 12.18 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 14839 381
GH/OmrMcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82.0 days-99.0 days 7 -0.34 degrees C 0.18 0.48 digital rectal thermometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14137 381
GH/OmrMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 163.6 mmHg 6.47 12.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14325 381
GH/OmrMcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 7 %change=VE during 2-3 min hypoxia/control during standard conditions 129.94 % 7.61 20.14 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 13725 381
GH/OmrMcwi absolute change in blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait female 82.0 days-99.0 days 3 0.04 null 0.01 0.02 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19773 381
GH/OmrMcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 6 105.3 % 7.41 18.16 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53985 381
GH/OmrMcwi blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait female 82.0 days-99.0 days 7 7.5 null 0.01 0.03 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20116 381
GH/OmrMcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 8 51.51 ml/min 3.56 10.06 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20124 381
GH/OmrMcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 7 49.29 ml/min 3.53 9.34 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20128 381
GH/OmrMcwi absolute change in blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait male 82.0 days-99.0 days 7 0.05 null 0.01 0.01 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18791 381
GH/OmrMcwi serum total protein level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount female 77.0 days-91.0 days 16 6.21 g/dl 0.1 0.38 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37006 401
GH/OmrMcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 7 46.43 ml/min 4.95 13.11 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 18707 381
GH/OmrMcwi serum calcium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount female 77.0 days-91.0 days 15 9.09 mg/dl 0.14 0.54 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36668 401
GH/OmrMcwi absolute change in partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount female 82.0 days-99.0 days 3 -47.45 mmHg 7.04 12.19 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19452 381
GH/OmrMcwi partial pressure of blood carbon dioxide (Pco2) controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood carbon dioxide amount male 82.0 days-99.0 days 7 27.35 mmHg 0.59 1.55 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18172 381
GH/OmrMcwi partial pressure of blood carbon dioxide (Pco2) controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood carbon dioxide amount female 82.0 days-99.0 days 7 25.23 mmHg 1.3 3.44 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18168 381
GH/OmrMcwi partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount female 82.0 days-99.0 days 3 49.32 mmHg 0.79 1.37 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 20464 381
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 10 6.93 % 2.81 8.88 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 49742 461
GH/OmrMcwi mean corpuscular volume controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait female 77.0 days-91.0 days 12 60.69 fl 1.07 3.71 automated blood cell counting method Moms and pups used in studies were fed Teklad 38789 401
GH/OmrMcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77.0 days-91.0 days 16 59.13 % 0.49 1.95 automated blood cell counting method Moms and pups used in studies were fed Teklad 39040 401
GH/OmrMcwi serum sodium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount male 77.0 days-91.0 days 18 143.67 mmol/l 0.75 3.16 standard blood chemistry panel Moms and pups used in studies were fed Teklad 39437 401
GH/OmrMcwi serum aspartate aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount female 77.0 days-91.0 days 16 151.44 U/l 14.22 56.89 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42814 401
GH/OmrMcwi plasma creatinine level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount male 77.0 days-91.0 days 18 0.37 mg/dl 0.02 0.08 automated plasma creatinine analysis Moms and pups used in studies were fed Teklad 39625 401
GH/OmrMcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 7 128.1 % 3.52 9.31 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 54318 381
GH/OmrMcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 8 107.93 % 7.2 20.38 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 53573 381
GH/OmrMcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 7 137.02 % 4.85 12.82 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 53593 381
GH/OmrMcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity female 77.0 days-91.0 days 17 59.13 % 0.86 3.54 microhematocrit tube assay with visual assessment Moms and pups used in studies were fed Teklad 59301 526
GH/OmrMcwi serum phosphate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount male 77.0 days-91.0 days 18 9.24 mg/dl 0.2 0.86 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37643 401
GH/OmrMcwi serum urea nitrogen level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount female 77.0 days-91.0 days 15 22.2 mg/dl 1.01 3.9 standard blood chemistry panel Moms and pups used in studies were fed Teklad 40872 401
GH/OmrMcwi serum urea nitrogen level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount male 77.0 days-91.0 days 18 20.78 mg/dl 0.56 2.37 standard blood chemistry panel Moms and pups used in studies were fed Teklad 40877 401
GH/OmrMcwi total white blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity female 77.0 days-91.0 days 12 3.64 x 1000 cells/ul 0.45 1.55 automated blood cell counting method Moms and pups used in studies were fed Teklad 40970 401
GH/OmrMcwi calculated pulmonary vascular resistance normalized to body weight controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 31 0.18 mmHg x min x kg x ml-1 0.01 0.05 fluid-filled catheter with pressure transducer in isolated perfused lung Moms and pups used in studies were fed Teklad 59596 526
GH/OmrMcwi lung dry weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass female 77.0 days-91.0 days 34 1.34 g/kg 0.03 0.15 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 59701 526
GH/OmrMcwi blood eosinophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity male 77.0 days-91.0 days 16 0.01 x 1000 cells/ul 0.01 0.02 automated blood cell counting method Moms and pups used in studies were fed Teklad 41696 401
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 168.85 mmHg 10.18 32.2 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48668 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 137.0 mmHg 5.88 17.64 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48730 461
GH/OmrMcwi methylene blue metabolism-surface area product after auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 21 10.84 ml/min/kg 0.76 3.49 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57642 526
GH/OmrMcwi methylene blue metabolism-surface area product after auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 21 8.6 ml/min/kg 0.51 2.35 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57647 526
GH/OmrMcwi methylene blue metabolism-surface area product without auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 21 13.19 ml/min/kg 0.8 3.64 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57844 526
GH/OmrMcwi fractional change in blood vessel diameter per unit change in intravascular pressure controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait female 77.0 days-91.0 days 30 0.03 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung Moms and pups used in studies were fed Teklad 58533 526
GH/OmrMcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 7 53.02 ml/min 2.81 7.42 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17474 381
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 174.33 mmHg 10.15 32.11 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45773 461
GH/OmrMcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 9 877.97 s 91.2 273.59 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45841 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 46.9 % 4.98 13.19 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48133 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 6 5.72 ml/min/g 0.45 1.1 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45096 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 147.04 beats/min 20.23 63.96 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45192 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 219.57 mmHg 18.35 48.56 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45375 461
GH/OmrMcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 7 139.84 breaths/min 5.18 13.7 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15587 381
GH/OmrMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 161.85 mmHg 3.08 8.15 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14417 381
GH/OmrMcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 7 0.35 ml 0.02 0.05 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14625 381
GH/OmrMcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 8 %change=VE during 2-3 min hypoxia/control during standard conditions 140.08 % 7.97 22.56 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14143 381
GH/OmrMcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 7 %change=VE during 2-3 min hypoxia/control during standard conditions 152.64 % 6.04 15.98 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14147 381
GH/OmrMcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 7 0.36 ml 0.04 0.12 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 13968 381
GH/OmrMcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 7 127.38 % 5.98 15.82 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53745 381
GH/OmrMcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82.0 days-99.0 days 8 37.39 degrees C 0.3 0.86 digital rectal thermometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17721 381
GH/OmrMcwi partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount female 82.0 days-99.0 days 7 56.31 mmHg 3.29 8.71 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18975 381
GH/OmrMcwi serum alkaline phosphatase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount female 77.0 days-91.0 days 16 243.88 U/l 8.6 34.4 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36423 401
GH/OmrMcwi serum total protein level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount male 77.0 days-91.0 days 18 6.22 g/dl 0.07 0.28 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37011 401
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 447.79 beats/min 11.25 22.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17492 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 429.6 beats/min 6.58 13.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17498 381
GH/OmrMcwi serum calcium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount male 77.0 days-91.0 days 18 9.33 mg/dl 0.18 0.78 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36673 401
GH/OmrMcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 8 140.58 breaths/min 10.0 28.27 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18149 381
GH/OmrMcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 7 46.46 ml/min 4.8 12.69 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 20253 381
GH/OmrMcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82.0 days-99.0 days 7 -0.17 degrees C 0.23 0.6 digital rectal thermometry Moms and pups used in studies were fed Teklad 20354 381
GH/OmrMcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 1126.31 s 65.26 195.77 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48929 461
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49.0 days-63.0 days 7 9.1 % 3.71 9.82 digital scale post excision weight measurement Moms and pups used in studies were fed Dyets 49634 461
GH/OmrMcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 1222.82 s 115.16 364.17 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 50271 461
GH/OmrMcwi mean corpuscular volume controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait male 77.0 days-91.0 days 16 61.01 fl 0.31 1.24 automated blood cell counting method Moms and pups used in studies were fed Teklad 38794 401
GH/OmrMcwi serum bicarbonate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount female 77.0 days-91.0 days 15 14.07 mmol/l 0.63 2.43 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42106 401
GH/OmrMcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77.0 days-91.0 days 12 60.03 % 1.06 3.67 automated blood cell counting method Moms and pups used in studies were fed Teklad 39035 401
GH/OmrMcwi serum chloride level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount male 77.0 days-91.0 days 18 108.44 mmol/l 0.74 3.13 standard blood chemistry panel Moms and pups used in studies were fed Teklad 39166 401
GH/OmrMcwi blood monocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity male 77.0 days-91.0 days 16 0.21 x 1000 cells/ul 0.03 0.11 automated blood cell counting method Moms and pups used in studies were fed Teklad 39723 401
GH/OmrMcwi mean corpuscular hemoglobin concentration controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77.0 days-91.0 days 16 32.58 g/dl 0.12 0.48 automated blood cell counting method Moms and pups used in studies were fed Teklad 39826 401
GH/OmrMcwi blood neutrophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity female 77.0 days-91.0 days 12 0.69 x 1000 cells/ul 0.14 0.47 automated blood cell counting method Moms and pups used in studies were fed Teklad 43268 401
GH/OmrMcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 8 121.04 % 6.71 18.99 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 53535 381
GH/OmrMcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 7 103.1 % 3.16 8.36 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 53577 381
GH/OmrMcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 8 133.84 % 9.94 28.12 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 53589 381
GH/OmrMcwi serum alanine aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount female 77.0 days-91.0 days 16 84.63 U/l 5.98 23.91 standard blood chemistry panel Moms and pups used in studies were fed Teklad 40758 401
GH/OmrMcwi plasma anion gap controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait male 77.0 days-91.0 days 18 24.39 mmol/l 0.61 2.57 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38310 401
GH/OmrMcwi blood eosinophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity female 77.0 days-91.0 days 12 0.03 x 1000 cells/ul 0.01 0.05 automated blood cell counting method Moms and pups used in studies were fed Teklad 41691 401
GH/OmrMcwi serum glucose level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount female 77.0 days-91.0 days 15 146.47 mg/dl 5.9 22.86 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38574 401
GH/OmrMcwi serum glucose level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount male 77.0 days-91.0 days 18 146.72 mg/dl 5.7 24.17 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38579 401
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 252.78 beats/min 11.94 35.83 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46518 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 5.0 mmHg 0.22 0.58 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 47535 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 59.35 % 3.41 10.23 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48506 461
GH/OmrMcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 1111.18 s 116.44 308.08 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48925 461
GH/OmrMcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82.0 days-99.0 days 7 37.79 degrees C 0.21 0.55 digital rectal thermometry Moms and pups used in studies were fed Teklad 16617 381
GH/OmrMcwi fractional change in blood vessel diameter per unit change in intravascular pressure controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait male 77.0 days-91.0 days 31 0.04 mmHg-1 0.0 0.02 fluid-filled catheter with pressure transducer in isolated perfused lung Moms and pups used in studies were fed Teklad 58538 526
GH/OmrMcwi heart right ventricle weight to left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass female 77.0 days-91.0 days 35 0.31 null 0.01 0.08 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 58777 526
GH/OmrMcwi heart right ventricle weight to left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass male 77.0 days-91.0 days 34 0.33 null 0.01 0.07 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 58782 526
GH/OmrMcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 8 51.33 ml/min 4.17 11.8 stop flow air displacement plethysmography Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17470 381
GH/OmrMcwi heart weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49.0 days-63.0 days 10 6.43 g/kg 0.32 1.01 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 45615 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 100.29 mmHg 15.02 39.74 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45688 461
GH/OmrMcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 7 641.83 s 47.92 126.78 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45837 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 5.49 mmHg 0.25 0.79 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47241 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 35.34 % 5.47 16.42 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48137 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 5.21 ml/min/g 0.91 2.73 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45100 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 9.69 ml/min/g 0.71 2.12 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 46291 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 176.87 beats/min 23.98 63.44 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45250 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 6 13.29 IU/g 2.15 5.27 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45367 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 8 10.99 IU/g 0.94 2.66 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45371 461