| SD-Ahrem2Sage |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.45 |
mg/g |
0.16 |
0.51 |
post excision weight measurement |
|
0 |
105895 |
3021 |
| SD-Ahrem2Sage |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.28 |
% |
0.02 |
0.05 |
post excision weight measurement |
|
0 |
105901 |
3021 |
| SD-Ahrem2Sage |
both ovaries weight to body weight ratio |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.05 |
% |
0.01 |
0.02 |
post excision weight measurement |
|
0 |
105921 |
3021 |
| SD-Ahrem2Sage |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.0 |
g/dl |
0.41 |
1.3 |
automated hematology analysis |
|
0 |
105953 |
3021 |
| SD-Ahrem2Sage |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.35 |
g/dl |
0.59 |
1.87 |
automated hematology analysis |
|
0 |
105955 |
3021 |
| SD-Ahrem2Sage |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
42.78 |
% |
2.31 |
7.3 |
automated hematology analysis |
|
0 |
105961 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
58.19 |
fl |
1.45 |
4.59 |
automated hematology analysis |
|
0 |
105973 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
57.25 |
fl |
1.42 |
4.49 |
automated hematology analysis |
|
0 |
105975 |
3021 |
| SD-Ahrem2Sage |
platelet count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1388.0 |
x 1000 /ul |
216.06 |
683.24 |
automated hematology analysis |
|
0 |
106005 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.54 |
g/dl |
0.58 |
1.83 |
automated hematology analysis |
|
0 |
105999 |
3021 |
| SD-Ahrem2Sage |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1341.2 |
x 1000 /ul |
182.15 |
576.01 |
automated hematology analysis |
|
0 |
106007 |
3021 |
| SD-Ahrem2Sage |
liver weight as percentage of body weight |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
3.43 |
% |
0.3 |
0.95 |
post excision weight measurement |
0.0 |
0 |
105726 |
3021 |
| SD-Ahrem2Sage |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1280.1 |
x 1000 /ul |
158.17 |
500.18 |
automated hematology analysis |
|
0 |
106011 |
3021 |
| SD-Ahrem2Sage |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
12.17 |
x 1000 cells/ul |
2.62 |
8.29 |
automated hematology analysis |
|
0 |
106019 |
3021 |
| SD-Ahrem2Sage |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
10.94 |
x 1000 cells/ul |
2.35 |
7.43 |
automated hematology analysis |
|
0 |
106023 |
3021 |
| SD-Ahrem2Sage |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
10.74 |
x 1000 cells/ul |
2.45 |
7.75 |
automated hematology analysis |
|
0 |
106027 |
3021 |
| SD-Ahrem2Sage |
blood lymphocyte count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
8.25 |
x 1000 cells/ul |
1.31 |
4.14 |
automated hematology analysis |
|
0 |
106041 |
3021 |
| SD-Ahrem2Sage |
blood eosinophil count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.18 |
x 1000 cells/ul |
0.18 |
0.57 |
automated hematology analysis |
|
0 |
106065 |
3021 |
| SD-Ahrem2Sage |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.09 |
x 1000 cells/ul |
0.03 |
0.09 |
automated hematology analysis |
|
0 |
106087 |
3021 |
| SD-Ahrem2Sage |
serum total bilirubin level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood bilirubin amount |
female |
84 days
| 4 |
0.05 |
mg/dl |
0.0 |
0.0 |
automated serum analysis |
|
0 |
106377 |
3025 |
| SD-Ahrem2Sage |
serum total protein level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood total protein amount |
male |
84 days
| 5 |
66.0 |
g/dl |
3.0 |
6.71 |
automated serum analysis |
|
0 |
106383 |
3025 |
| SD-Ahrem2Sage |
serum triglyceride level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood triglyceride amount |
male |
84 days
| 5 |
128.4 |
mg/dl |
26.0 |
58.14 |
automated serum analysis |
|
0 |
106403 |
3025 |
| SD-Ahrem2Sage |
serum chloride level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood chloride amount |
male |
84 days
| 5 |
101.0 |
mmol/l |
2.0 |
4.47 |
automated serum analysis |
|
0 |
106427 |
3025 |
| SD-Ahrem2Sage |
serum calcium level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood calcium amount |
male |
84 days
| 5 |
13.1 |
mg/dl |
0.7 |
1.57 |
automated serum analysis |
|
0 |
106431 |
3025 |
| SD-Ahrem2Sage |
serum calcium level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood calcium amount |
female |
84 days
| 4 |
13.9 |
mg/dl |
0.4 |
0.8 |
automated serum analysis |
|
0 |
106433 |
3025 |
| SD-Ahrem2Sage |
liver weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
liver mass |
female |
84 days
| 5 |
4.11 |
g |
0.48 |
1.07 |
post excision weight measurement |
|
0 |
106445 |
3025 |
| SD-Ahrem2Sage |
kidney weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
kidney mass |
female |
84 days
| 5 |
0.99 |
g |
0.09 |
0.2 |
post excision weight measurement |
|
0 |
106449 |
3025 |
| SD-Ahrem2Sage |
pancreas weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
pancreas mass |
female |
84 days
| 5 |
330.0 |
mg |
110.0 |
245.97 |
post excision weight measurement |
|
0 |
106457 |
3025 |
| SD-Ahrem2Sage |
brain weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
brain mass |
male |
84 days
| 5 |
0.5 |
g |
0.01 |
0.02 |
post excision weight measurement |
|
0 |
106467 |
3025 |
| SD-Ahrem2Sage |
thymus weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
thymus mass |
female |
84 days
| 5 |
0.17 |
g |
0.03 |
0.07 |
post excision weight measurement |
|
0 |
106465 |
3025 |
| SD-Ahrem2Sage |
both testes wet weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
testis mass |
male |
84 days
| 12 |
0.91 |
g |
0.03 |
0.1 |
post excision weight measurement |
|
0 |
106489 |
3025 |
| SD-Ahrem2Sage |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.65 |
x 10E6 cells/ul |
0.3 |
0.95 |
automated hematology analysis |
|
0 |
105943 |
3021 |
| SD-Ahrem2Sage |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.1 |
g/dl |
0.61 |
1.93 |
automated hematology analysis |
|
0 |
105947 |
3021 |
| SD-Ahrem2Sage |
white blood cell count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
10.8 |
x 1000 cells/ul |
1.5 |
4.74 |
automated hematology analysis |
|
0 |
106017 |
3021 |
| SD-Ahrem2Sage |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.92 |
x 1000 cells/ul |
0.78 |
2.47 |
automated hematology analysis |
|
0 |
106037 |
3021 |
| SD-Ahrem2Sage |
serum total bilirubin level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood bilirubin amount |
male |
84 days
| 5 |
0.06 |
mg/dl |
0.02 |
0.04 |
automated serum analysis |
|
0 |
106375 |
3025 |
| SD-Ahrem2Sage |
serum creatinine level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood creatinine amount |
female |
84 days
| 4 |
0.38 |
mg/dl |
0.05 |
0.1 |
automated serum analysis |
|
0 |
106413 |
3025 |
| SD-Ahrem2Sage |
thymus weight to body weight ratio |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.61 |
mg/g |
0.19 |
0.6 |
post excision weight measurement |
|
0 |
105885 |
3021 |
| SD-Ahrem2Sage |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.6 |
mg/g |
0.29 |
0.92 |
post excision weight measurement |
|
0 |
105887 |
3021 |
| SD-Ahrem2Sage |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.75 |
% |
0.05 |
0.16 |
post excision weight measurement |
|
0 |
105917 |
3021 |
| SD-Ahrem2Sage |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.04 |
% |
0.02 |
0.05 |
post excision weight measurement |
|
0 |
105927 |
3021 |
| SD-Ahrem2Sage |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.06 |
% |
0.01 |
0.02 |
post excision weight measurement |
|
0 |
105929 |
3021 |
| SD-Ahrem2Sage |
blood hemoglobin level |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
14.01 |
g/dl |
0.62 |
1.96 |
automated hematology analysis |
|
0 |
105945 |
3021 |
| SD-Ahrem2Sage |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
13.83 |
g/dl |
0.62 |
1.96 |
automated hematology analysis |
|
0 |
105949 |
3021 |
| SD-Ahrem2Sage |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
44.14 |
% |
1.77 |
5.6 |
automated hematology analysis |
|
0 |
105967 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
58.02 |
fl |
1.6 |
5.06 |
automated hematology analysis |
|
0 |
105971 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular volume |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
58.44 |
fl |
0.87 |
2.75 |
automated hematology analysis |
|
0 |
105969 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.92 |
pg |
0.39 |
1.23 |
automated hematology analysis |
|
0 |
105981 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.64 |
pg |
0.59 |
1.87 |
automated hematology analysis |
|
0 |
105987 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.76 |
pg |
0.6 |
1.9 |
automated hematology analysis |
|
0 |
105991 |
3021 |
| SD-Ahrem2Sage |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1368.22 |
x 1000 /ul |
85.21 |
269.46 |
automated hematology analysis |
|
0 |
106013 |
3021 |
| SD-Ahrem2Sage |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1335.5 |
x 1000 /ul |
356.55 |
1127.51 |
automated hematology analysis |
|
0 |
106015 |
3021 |
| SD-Ahrem2Sage |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.56 |
x 1000 cells/ul |
0.57 |
1.8 |
automated hematology analysis |
|
0 |
106033 |
3021 |
| SD-Ahrem2Sage |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.67 |
x 1000 cells/ul |
0.54 |
1.71 |
automated hematology analysis |
|
0 |
106035 |
3021 |
| SD-Ahrem2Sage |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
9.39 |
x 1000 cells/ul |
1.63 |
5.15 |
automated hematology analysis |
|
0 |
106043 |
3021 |
| SD-Ahrem2Sage |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
8.41 |
x 1000 cells/ul |
1.9 |
6.01 |
automated hematology analysis |
|
0 |
106051 |
3021 |
| SD-Ahrem2Sage |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.32 |
x 1000 cells/ul |
0.08 |
0.25 |
automated hematology analysis |
|
0 |
106059 |
3021 |
| SD-Ahrem2Sage |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.28 |
x 1000 cells/ul |
0.09 |
0.28 |
automated hematology analysis |
|
0 |
106063 |
3021 |
| SD-Ahrem2Sage |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.16 |
x 1000 cells/ul |
0.05 |
0.16 |
automated hematology analysis |
|
0 |
106071 |
3021 |
| SD-Ahrem2Sage |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.15 |
x 1000 cells/ul |
0.03 |
0.09 |
automated hematology analysis |
|
0 |
106075 |
3021 |
| SD-Ahrem2Sage |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.1 |
x 1000 cells/ul |
0.04 |
0.13 |
automated hematology analysis |
|
0 |
106083 |
3021 |
| SD-Ahrem2Sage |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
3.55 |
% |
0.18 |
0.56 |
post excision weight measurement |
0.0 |
0 |
105730 |
3021 |
| SD-Ahrem2Sage |
serum total protein level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood total protein amount |
female |
84 days
| 4 |
65.0 |
g/dl |
4.0 |
8.0 |
automated serum analysis |
|
0 |
106385 |
3025 |
| SD-Ahrem2Sage |
blood albumin level to blood globulin level ratio |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood albumin amount |
male |
84 days
| 5 |
1.8 |
null |
0.2 |
0.45 |
automated serum analysis |
|
0 |
106395 |
3025 |
| SD-Ahrem2Sage |
blood albumin level to blood globulin level ratio |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood albumin amount |
female |
84 days
| 4 |
2.0 |
null |
0.1 |
0.2 |
automated serum analysis |
|
0 |
106397 |
3025 |
| SD-Ahrem2Sage |
serum total cholesterol level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood cholesterol amount |
male |
84 days
| 5 |
102.6 |
mg/dl |
12.8 |
28.62 |
automated serum analysis |
|
0 |
106399 |
3025 |
| SD-Ahrem2Sage |
serum glucose level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood glucose amount |
male |
84 days
| 5 |
288.6 |
mg/dl |
59.3 |
132.6 |
automated serum analysis |
|
0 |
106415 |
3025 |
| SD-Ahrem2Sage |
serum glucose level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood glucose amount |
female |
84 days
| 4 |
333.3 |
mg/dl |
90.0 |
180.0 |
automated serum analysis |
|
0 |
106417 |
3025 |
| SD-Ahrem2Sage |
serum chloride level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood chloride amount |
female |
84 days
| 4 |
99.0 |
mmol/l |
2.3 |
4.6 |
automated serum analysis |
|
0 |
106429 |
3025 |
| SD-Ahrem2Sage |
serum potassium level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood potassium amount |
female |
84 days
| 4 |
8.2 |
mmol/l |
0.6 |
1.2 |
automated serum analysis |
|
0 |
106425 |
3025 |
| SD-Ahrem2Sage |
serum phosphate level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood phosphate amount |
female |
84 days
| 4 |
14.8 |
mg/dl |
2.5 |
5.0 |
automated serum analysis |
|
0 |
106437 |
3025 |
| SD-Ahrem2Sage |
body weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
body mass |
female |
84 days
| 5 |
252.7 |
g |
18.8 |
42.04 |
body weighing method |
|
0 |
106441 |
3025 |
| SD-Ahrem2Sage |
liver weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
liver mass |
male |
84 days
| 5 |
4.47 |
g |
0.22 |
0.49 |
post excision weight measurement |
|
0 |
106443 |
3025 |
| SD-Ahrem2Sage |
heart weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
heart mass |
male |
84 days
| 5 |
0.38 |
g |
0.02 |
0.04 |
post excision weight measurement |
|
0 |
106451 |
3025 |
| SD-Ahrem2Sage |
spleen weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
spleen mass |
female |
84 days
| 5 |
0.26 |
g |
0.01 |
0.02 |
post excision weight measurement |
|
0 |
106461 |
3025 |
| SD-Ahrem2Sage |
thymus weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
thymus mass |
male |
84 days
| 5 |
0.17 |
g |
0.03 |
0.07 |
post excision weight measurement |
|
0 |
106463 |
3025 |
| SD-Ahrem2Sage |
epididymides weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
epididymis mass |
male |
84 days
| 12 |
0.54 |
g |
0.06 |
0.21 |
post excision weight measurement |
|
0 |
106491 |
3025 |
| SD-Ahrem2Sage |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.5 |
x 10E6 cells/ul |
0.28 |
0.89 |
automated hematology analysis |
|
0 |
105939 |
3021 |
| SD-Ahrem2Sage |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
3.43 |
% |
0.27 |
0.84 |
post excision weight measurement |
0.0 |
0 |
105728 |
3021 |
| SD-Ahrem2Sage |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
11.41 |
x 1000 cells/ul |
2.58 |
8.16 |
automated hematology analysis |
|
0 |
106025 |
3021 |
| SD-Ahrem2Sage |
blood neutrophil count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.89 |
x 1000 cells/ul |
0.62 |
1.96 |
automated hematology analysis |
|
0 |
106029 |
3021 |
| SD-Ahrem2Sage |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.35 |
x 1000 cells/ul |
0.18 |
0.57 |
automated hematology analysis |
|
0 |
106057 |
3021 |
| SD-Ahrem2Sage |
serum alanine aminotransferase activity level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood alanine transaminase amount |
female |
84 days
| 4 |
77.3 |
U/l |
21.6 |
43.2 |
automated serum analysis |
|
0 |
106365 |
3025 |
| SD-Ahrem2Sage |
prostate gland weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
prostate mass |
male |
84 days
| 12 |
0.27 |
g |
0.04 |
0.14 |
post excision weight measurement |
|
0 |
106493 |
3025 |
| SD-Ahrem2Sage |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.7 |
mg/g |
0.3 |
0.95 |
post excision weight measurement |
|
0 |
105891 |
3021 |
| SD-Ahrem2Sage |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.6 |
mg/g |
0.23 |
0.73 |
post excision weight measurement |
|
0 |
105889 |
3021 |
| SD-Ahrem2Sage |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.28 |
% |
0.02 |
0.07 |
post excision weight measurement |
|
0 |
105903 |
3021 |
| SD-Ahrem2Sage |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.05 |
% |
0.01 |
0.03 |
post excision weight measurement |
|
0 |
105925 |
3021 |
| SD-Ahrem2Sage |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.35 |
x 10E6 cells/ul |
0.39 |
1.23 |
automated hematology analysis |
|
0 |
105937 |
3021 |
| SD-Ahrem2Sage |
blood hemoglobin level |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
13.98 |
g/dl |
0.52 |
1.64 |
automated hematology analysis |
|
0 |
105951 |
3021 |
| SD-Ahrem2Sage |
hematocrit |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
43.31 |
% |
1.67 |
5.28 |
automated hematology analysis |
|
0 |
105957 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
58.74 |
fl |
1.09 |
3.45 |
automated hematology analysis |
|
0 |
105977 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.81 |
pg |
0.62 |
1.96 |
automated hematology analysis |
|
0 |
105983 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.4 |
g/dl |
0.6 |
1.9 |
automated hematology analysis |
|
0 |
105995 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.48 |
g/dl |
0.92 |
2.91 |
automated hematology analysis |
|
0 |
106001 |
3021 |
| SD-Ahrem2Sage |
white blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
leukocyte quantity |
female |
84 days
| 10 |
10.67 |
x 1000 cells/ul |
3.06 |
9.68 |
automated hematology analysis |
|
0 |
106021 |
3021 |
| SD-Ahrem2Sage |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.33 |
x 1000 cells/ul |
0.11 |
0.35 |
automated hematology analysis |
|
0 |
106055 |
3021 |
| SD-Ahrem2Sage |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.22 |
x 1000 cells/ul |
0.18 |
0.57 |
automated hematology analysis |
|
0 |
106067 |
3021 |
| SD-Ahrem2Sage |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.09 |
x 1000 cells/ul |
0.03 |
0.09 |
automated hematology analysis |
|
0 |
106085 |
3021 |
| SD-Ahrem2Sage |
serum albumin level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood albumin amount |
male |
84 days
| 5 |
4.2 |
g/dl |
0.2 |
0.45 |
automated serum analysis |
|
0 |
106387 |
3025 |
| SD-Ahrem2Sage |
serum globulin level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood globulin amount |
male |
84 days
| 5 |
2.4 |
g/dl |
0.2 |
0.45 |
automated serum analysis |
|
0 |
106391 |
3025 |
| SD-Ahrem2Sage |
serum urea nitrogen level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood urea nitrogen amount |
male |
84 days
| 5 |
22.6 |
mg/dl |
2.3 |
5.14 |
automated serum analysis |
|
0 |
106407 |
3025 |
| SD-Ahrem2Sage |
serum creatinine level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood creatinine amount |
male |
84 days
| 5 |
0.3 |
mg/dl |
0.0 |
0.0 |
automated serum analysis |
|
0 |
106411 |
3025 |
| SD-Ahrem2Sage |
heart weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
heart mass |
female |
84 days
| 5 |
0.41 |
g |
0.05 |
0.11 |
post excision weight measurement |
|
0 |
106453 |
3025 |
| SD-Ahrem2Sage |
thyroid gland weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
thyroid gland mass |
male |
84 days
| 5 |
0.01 |
g |
0.0 |
0.0 |
post excision weight measurement |
|
0 |
106475 |
3025 |
| SD-Ahrem2Sage |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.05 |
% |
0.01 |
0.03 |
post excision weight measurement |
|
0 |
105923 |
3021 |
| SD-Ahrem2Sage |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.76 |
% |
0.05 |
0.16 |
post excision weight measurement |
|
0 |
105919 |
3021 |
| SD-Ahrem2Sage |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
8.84 |
x 1000 cells/ul |
1.79 |
5.66 |
automated hematology analysis |
|
0 |
106049 |
3021 |
| SD-Ahrem2Sage |
serum albumin level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood albumin amount |
female |
84 days
| 4 |
4.3 |
g/dl |
0.3 |
0.6 |
automated serum analysis |
|
0 |
106389 |
3025 |
| SD-Ahrem2Sage |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
3.31 |
% |
0.21 |
0.67 |
post excision weight measurement |
0.0 |
0 |
105731 |
3021 |
| SD-Ahrem2Sage |
spleen weight to body weight ratio |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.29 |
% |
0.02 |
0.07 |
post excision weight measurement |
|
0 |
105897 |
3021 |
| SD-Ahrem2Sage |
brain weight to body weight ratio |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.74 |
% |
0.04 |
0.14 |
post excision weight measurement |
|
0 |
105909 |
3021 |
| SD-Ahrem2Sage |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.75 |
% |
0.05 |
0.16 |
post excision weight measurement |
|
0 |
105913 |
3021 |
| SD-Ahrem2Sage |
red blood cell count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.41 |
x 10E6 cells/ul |
0.36 |
1.14 |
automated hematology analysis |
|
0 |
105933 |
3021 |
| SD-Ahrem2Sage |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.34 |
x 10E6 cells/ul |
0.2 |
0.63 |
automated hematology analysis |
|
0 |
105941 |
3021 |
| SD-Ahrem2Sage |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
42.9 |
% |
1.63 |
5.15 |
automated hematology analysis |
|
0 |
105963 |
3021 |
| SD-Ahrem2Sage |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
43.12 |
% |
0.91 |
2.88 |
automated hematology analysis |
|
0 |
105965 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular volume |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte size trait |
female |
84 days
| 10 |
57.73 |
fl |
1.91 |
6.04 |
automated hematology analysis |
|
0 |
105979 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
18.82 |
pg |
0.65 |
2.06 |
automated hematology analysis |
|
0 |
105985 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin concentration |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.37 |
g/dl |
0.7 |
2.21 |
automated hematology analysis |
|
0 |
105993 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.37 |
g/dl |
0.85 |
2.69 |
automated hematology analysis |
|
0 |
105997 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin concentration |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
32.48 |
g/dl |
0.85 |
2.69 |
automated hematology analysis |
|
0 |
106003 |
3021 |
| SD-Ahrem2Sage |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
3.35 |
% |
0.29 |
0.93 |
post excision weight measurement |
0.0 |
0 |
105727 |
3021 |
| SD-Ahrem2Sage |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.99 |
x 1000 cells/ul |
0.97 |
3.07 |
automated hematology analysis |
|
0 |
106031 |
3021 |
| SD-Ahrem2Sage |
blood monocyte count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.31 |
x 1000 cells/ul |
0.09 |
0.28 |
automated hematology analysis |
|
0 |
106053 |
3021 |
| SD-Ahrem2Sage |
blood basophil count |
vehicle control condition (5 ml/kg) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.08 |
x 1000 cells/ul |
0.02 |
0.06 |
automated hematology analysis |
|
0 |
106077 |
3021 |
| SD-Ahrem2Sage |
serum alkaline phosphatase activity level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood alkaline phosphatase amount |
female |
84 days
| 4 |
140.8 |
U/l |
54.5 |
109.0 |
automated serum analysis |
|
0 |
106373 |
3025 |
| SD-Ahrem2Sage |
serum sodium level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood sodium amount |
male |
84 days
| 5 |
149.2 |
mmol/l |
1.1 |
2.46 |
automated serum analysis |
|
0 |
106419 |
3025 |
| SD-Ahrem2Sage |
serum potassium level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood potassium amount |
male |
84 days
| 5 |
7.6 |
mmol/l |
0.7 |
1.57 |
automated serum analysis |
|
0 |
106423 |
3025 |
| SD-Ahrem2Sage |
body weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
body mass |
male |
84 days
| 5 |
380.5 |
g |
12.6 |
28.17 |
body weighing method |
|
0 |
106439 |
3025 |
| SD-Ahrem2Sage |
spleen weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
spleen mass |
male |
84 days
| 5 |
0.24 |
g |
0.02 |
0.04 |
post excision weight measurement |
|
0 |
106459 |
3025 |
| SD-Ahrem2Sage |
thyroid gland weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
thyroid gland mass |
female |
84 days
| 5 |
0.01 |
g |
0.0 |
0.0 |
post excision weight measurement |
|
0 |
106477 |
3025 |
| SD-Ahrem2Sage |
pituitary gland weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
pituitary gland mass |
male |
84 days
| 5 |
0.0 |
g |
0.0 |
0.0 |
post excision weight measurement |
|
0 |
106483 |
3025 |
| SD-Ahrem2Sage |
both ovaries weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
ovary mass |
female |
84 days
| 12 |
0.04 |
g |
0.0 |
0.01 |
post excision weight measurement |
|
0 |
106487 |
3025 |
| SD-Ahrem2Sage |
both ovaries weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
ovary mass |
female |
84 days
| 10 |
0.04 |
% |
0.01 |
0.03 |
post excision weight measurement |
|
0 |
105931 |
3021 |
| SD-Ahrem2Sage |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.12 |
x 1000 cells/ul |
0.03 |
0.09 |
automated hematology analysis |
|
0 |
106073 |
3021 |
| SD-Ahrem2Sage |
blood eosinophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
eosinophil quantity |
female |
84 days
| 10 |
0.15 |
x 1000 cells/ul |
0.05 |
0.16 |
automated hematology analysis |
|
0 |
106069 |
3021 |
| SD-Ahrem2Sage |
serum aspartate aminotransferase activity level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood aspartate transaminase amount |
female |
84 days
| 4 |
126.5 |
U/l |
14.7 |
29.4 |
automated serum analysis |
|
0 |
106369 |
3025 |
| SD-Ahrem2Sage |
serum total cholesterol level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood cholesterol amount |
female |
84 days
| 4 |
106.5 |
mg/dl |
17.5 |
35.0 |
automated serum analysis |
|
0 |
106401 |
3025 |
| SD-Ahrem2Sage |
serum urea nitrogen level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood urea nitrogen amount |
female |
84 days
| 4 |
23.0 |
mg/dl |
1.6 |
3.2 |
automated serum analysis |
|
0 |
106409 |
3025 |
| SD-Ahrem2Sage |
pituitary gland weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
pituitary gland mass |
female |
84 days
| 5 |
0.01 |
g |
0.0 |
0.0 |
post excision weight measurement |
|
0 |
106485 |
3025 |
| SD-Ahrem2Sage |
thymus weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
thymus mass |
female |
84 days
| 10 |
1.61 |
mg/g |
0.2 |
0.63 |
post excision weight measurement |
|
0 |
105893 |
3021 |
| SD-Ahrem2Sage |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.27 |
% |
0.01 |
0.04 |
post excision weight measurement |
|
0 |
105905 |
3021 |
| SD-Ahrem2Sage |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.73 |
% |
0.05 |
0.15 |
post excision weight measurement |
|
0 |
105915 |
3021 |
| SD-Ahrem2Sage |
red blood cell count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
7.51 |
x 10E6 cells/ul |
0.4 |
1.26 |
automated hematology analysis |
|
0 |
105935 |
3021 |
| SD-Ahrem2Sage |
hematocrit |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
erythrocyte quantity |
female |
84 days
| 10 |
43.56 |
% |
1.96 |
6.2 |
automated hematology analysis |
|
0 |
105959 |
3021 |
| SD-Ahrem2Sage |
mean corpuscular hemoglobin |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
blood hemoglobin amount |
female |
84 days
| 10 |
19.08 |
pg |
0.53 |
1.68 |
automated hematology analysis |
|
0 |
105989 |
3021 |
| SD-Ahrem2Sage |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
3.32 |
% |
0.28 |
0.87 |
post excision weight measurement |
0.0 |
0 |
105729 |
3021 |
| SD-Ahrem2Sage |
platelet count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
platelet quantity |
female |
84 days
| 10 |
1464.56 |
x 1000 /ul |
195.34 |
617.72 |
automated hematology analysis |
|
0 |
106009 |
3021 |
| SD-Ahrem2Sage |
blood neutrophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
neutrophil quantity |
female |
84 days
| 10 |
1.71 |
x 1000 cells/ul |
0.84 |
2.66 |
automated hematology analysis |
|
0 |
106039 |
3021 |
| SD-Ahrem2Sage |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (100 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
8.58 |
x 1000 cells/ul |
1.97 |
6.23 |
automated hematology analysis |
|
0 |
106047 |
3021 |
| SD-Ahrem2Sage |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.12 |
x 1000 cells/ul |
0.04 |
0.13 |
automated hematology analysis |
|
0 |
106079 |
3021 |
| SD-Ahrem2Sage |
serum alanine aminotransferase activity level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood alanine transaminase amount |
male |
84 days
| 5 |
59.4 |
U/l |
14.6 |
32.65 |
automated serum analysis |
|
0 |
106363 |
3025 |
| SD-Ahrem2Sage |
serum aspartate aminotransferase activity level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood aspartate transaminase amount |
male |
84 days
| 5 |
154.4 |
U/l |
8.4 |
18.78 |
automated serum analysis |
|
0 |
106367 |
3025 |
| SD-Ahrem2Sage |
serum alkaline phosphatase activity level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood alkaline phosphatase amount |
male |
84 days
| 5 |
77.8 |
U/l |
14.8 |
33.09 |
automated serum analysis |
|
0 |
106371 |
3025 |
| SD-Ahrem2Sage |
serum triglyceride level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood triglyceride amount |
female |
84 days
| 4 |
105.7 |
mg/dl |
28.1 |
56.2 |
automated serum analysis |
|
0 |
106405 |
3025 |
| SD-Ahrem2Sage |
serum phosphate level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood phosphate amount |
male |
84 days
| 5 |
12.7 |
mg/dl |
1.9 |
4.25 |
automated serum analysis |
|
0 |
106435 |
3025 |
| SD-Ahrem2Sage |
kidney weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
kidney mass |
male |
84 days
| 5 |
0.94 |
g |
0.07 |
0.16 |
post excision weight measurement |
|
0 |
106447 |
3025 |
| SD-Ahrem2Sage |
pancreas weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
pancreas mass |
male |
84 days
| 5 |
280.0 |
mg |
40.0 |
89.44 |
post excision weight measurement |
|
0 |
106455 |
3025 |
| SD-Ahrem2Sage |
lung weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
lung mass |
male |
84 days
| 5 |
0.55 |
g |
0.05 |
0.11 |
post excision weight measurement |
|
0 |
106471 |
3025 |
| SD-Ahrem2Sage |
adrenal gland weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
adrenal gland mass |
male |
84 days
| 5 |
21.0 |
mg |
17.0 |
38.01 |
post excision weight measurement |
|
0 |
106479 |
3025 |
| SD-Ahrem2Sage |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.29 |
% |
0.04 |
0.12 |
post excision weight measurement |
|
0 |
105899 |
3021 |
| SD-Ahrem2Sage |
spleen weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
spleen mass |
female |
84 days
| 10 |
0.28 |
% |
0.03 |
0.08 |
post excision weight measurement |
|
0 |
105907 |
3021 |
| SD-Ahrem2Sage |
brain weight to body weight ratio |
2,3,7,8-tetrachlorodibenzo-p-dioxin (3 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
brain mass |
female |
84 days
| 10 |
0.76 |
% |
0.04 |
0.13 |
post excision weight measurement |
|
0 |
105911 |
3021 |
| SD-Ahrem2Sage |
blood lymphocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
lymphocyte quantity |
female |
84 days
| 10 |
8.43 |
x 1000 cells/ul |
2.48 |
7.84 |
automated hematology analysis |
|
0 |
106045 |
3021 |
| SD-Ahrem2Sage |
blood monocyte count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (300 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
monocyte quantity |
female |
84 days
| 10 |
0.32 |
x 1000 cells/ul |
0.13 |
0.41 |
automated hematology analysis |
|
0 |
106061 |
3021 |
| SD-Ahrem2Sage |
blood basophil count |
2,3,7,8-tetrachlorodibenzo-p-dioxin (22 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
basophil quantity |
female |
84 days
| 10 |
0.09 |
x 1000 cells/ul |
0.04 |
0.13 |
automated hematology analysis |
|
0 |
106081 |
3021 |
| SD-Ahrem2Sage |
serum globulin level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood globulin amount |
female |
84 days
| 4 |
2.2 |
g/dl |
0.1 |
0.2 |
automated serum analysis |
|
0 |
106393 |
3025 |
| SD-Ahrem2Sage |
serum sodium level |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
blood sodium amount |
female |
84 days
| 4 |
146.8 |
mmol/l |
2.1 |
4.2 |
automated serum analysis |
|
0 |
106421 |
3025 |
| SD-Ahrem2Sage |
brain weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
brain mass |
female |
84 days
| 5 |
0.67 |
g |
0.03 |
0.07 |
post excision weight measurement |
|
0 |
106469 |
3025 |
| SD-Ahrem2Sage |
lung weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
lung mass |
female |
84 days
| 5 |
0.84 |
g |
0.35 |
0.78 |
post excision weight measurement |
|
0 |
106473 |
3025 |
| SD-Ahrem2Sage |
adrenal gland weight |
control condition (for 84 days) |
Harrill JA, et al., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. |
adrenal gland mass |
female |
84 days
| 5 |
25.0 |
mg |
2.0 |
4.47 |
post excision weight measurement |
|
0 |
106481 |
3025 |
