GK/Jcl |
heart weight |
standard diet |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
heart mass |
male |
84 days
| 8 |
0.98 |
g |
0.01 |
0.04 |
post excision weight measurement |
0.0 |
|
0 |
|
103061 |
2785 |
GK/Jcl |
heart weight |
Omacor (400 mg/kg/d) (for 56 days) |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
heart mass |
male |
84 days
| 8 |
1.03 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
0 |
|
103062 |
2785 |
GK/Jcl |
food intake rate |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
eating behavior trait |
male |
52 days
| 6 |
11.86 |
g/d |
0.4 |
0.98 |
food intake measuring method |
0.0 |
|
0 |
|
103934 |
2884 |
GK/Jcl |
serum insulin level |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood insulin amount |
male |
52 days
| 6 |
0.0 |
mg/dl |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
103937 |
2884 |
GK/Jcl |
serum insulin level |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood insulin amount |
male |
52 days
| 6 |
0.0 |
mg/dl |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
103938 |
2884 |
GK/Jcl |
calculated liver glutathione level |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver glutathione amount |
male |
52 days
| 6 |
562.62 |
umol/min/mg |
49.52 |
121.3 |
enzyme or transport activity assay |
0.0 |
|
0 |
|
103952 |
2884 |
GK/Jcl |
serum total cholesterol level |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood cholesterol amount |
male |
52 days
| 6 |
117.47 |
mg/dl |
4.36 |
10.68 |
liquid phase colorimetry |
0.0 |
|
0 |
|
103964 |
2884 |
GK/Jcl |
serum total cholesterol level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood cholesterol amount |
male |
52 days
| 6 |
86.45 |
mg/dl |
3.98 |
9.75 |
liquid phase colorimetry |
0.0 |
|
0 |
|
103965 |
2884 |
GK/Jcl |
serum high density lipoprotein cholesterol level to serum total cholesterol level ratio |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood cholesterol amount |
male |
52 days
| 6 |
0.94 |
null |
0.02 |
0.05 |
liquid phase colorimetry |
0.0 |
|
0 |
|
103968 |
2884 |
GK/Jcl |
blood glucose level |
control condition then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
31 days
| 6 |
113.71 |
mg/dl |
5.32 |
13.03 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103917 |
2884 |
GK/Jcl |
blood glucose level |
control condition then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
38 days
| 6 |
122.1 |
mg/dl |
2.58 |
6.32 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103921 |
2884 |
GK/Jcl |
blood glucose level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 21 days) then fasting (for 12 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
45 days
| 6 |
128.28 |
mg/dl |
5.86 |
14.35 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103927 |
2884 |
GK/Jcl |
blood glucose level |
controlled hesperidin content diet (1 %) (for 28 days) then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
52 days
| 6 |
104.14 |
mg/dl |
4.03 |
9.87 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103930 |
2884 |
GK/Jcl |
serum triglyceride level |
control condition |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood triglyceride amount |
male |
154 days
| 7 |
158.41 |
mg/dl |
17.7 |
46.83 |
solid phase colorimetry |
0.0 |
|
0 |
|
110227 |
3167 |
GK/Jcl |
serum insulin level |
fasting |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood insulin amount |
male |
154 days
| 7 |
0.0 |
mg/dl |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
110215 |
3167 |
GK/Jcl |
blood glucose level |
controlled hesperidin content diet (1 %) (for 7 days) then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
31 days
| 6 |
118.28 |
mg/dl |
4.58 |
11.22 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103918 |
2884 |
GK/Jcl |
heart left ventricle weight |
standard diet |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
heart left ventricle mass |
male |
84 days
| 8 |
0.68 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
103065 |
2785 |
GK/Jcl |
heart left ventricle weight to body weight ratio |
Omacor (400 mg/kg/d) (for 56 days) |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
heart left ventricle mass |
male |
84 days
| 8 |
1.98 |
mg/g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
0 |
|
103070 |
2785 |
GK/Jcl |
body weight |
controlled hesperidin content diet (1 %) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
body mass |
male |
24 days
| 6 |
52.98 |
g |
1.45 |
3.55 |
body weighing method |
0.0 |
|
0 |
|
103906 |
2884 |
GK/Jcl |
body weight |
controlled hesperidin content diet (1 %) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
body mass |
male |
24 days
| 6 |
172.3 |
g |
5.83 |
14.28 |
body weighing method |
0.0 |
|
0 |
|
103910 |
2884 |
GK/Jcl |
blood glucose level |
control condition then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
45 days
| 6 |
144.42 |
mg/dl |
5.26 |
12.88 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103925 |
2884 |
GK/Jcl |
serum insulin level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood insulin amount |
male |
52 days
| 6 |
0.0 |
mg/dl |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
103939 |
2884 |
GK/Jcl |
serum adiponectin level |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood adiponectin amount |
male |
52 days
| 6 |
18.26 |
ng/ml |
2.14 |
5.24 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
103942 |
2884 |
GK/Jcl |
serum hesperetin level |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood flavanone amount |
male |
52 days
| 6 |
1.55 |
umol/l |
0.71 |
1.74 |
high-performance liquid chromatography |
0.0 |
|
0 |
|
103948 |
2884 |
GK/Jcl |
liver glucokinase level |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver glucokinase activity |
male |
52 days
| 6 |
194.14 |
umol/min/mg |
19.58 |
47.96 |
enzyme or transport activity assay |
0.0 |
|
0 |
|
103955 |
2884 |
GK/Jcl |
serum triglyceride level |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood triglyceride amount |
male |
52 days
| 6 |
114.12 |
mg/dl |
14.21 |
34.81 |
serum triglyceride analysis |
0.0 |
|
0 |
|
103959 |
2884 |
GK/Jcl |
serum total cholesterol level |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood cholesterol amount |
male |
52 days
| 6 |
182.95 |
mg/dl |
5.35 |
13.1 |
liquid phase colorimetry |
0.0 |
|
0 |
|
103963 |
2884 |
GK/Jcl |
serum high density lipoprotein cholesterol level to serum total cholesterol level ratio |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood cholesterol amount |
male |
52 days
| 6 |
0.9 |
null |
0.07 |
0.17 |
liquid phase colorimetry |
0.0 |
|
0 |
|
103969 |
2884 |
GK/Jcl |
liver triglyceride level |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver triglyceride amount |
male |
52 days
| 6 |
16.41 |
mg/g |
1.38 |
3.38 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
103971 |
2884 |
GK/Jcl |
serum total cholesterol level |
control condition |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood cholesterol amount |
male |
154 days
| 7 |
34.36 |
mg/dl |
0.77 |
2.04 |
solid phase colorimetry |
0.0 |
|
0 |
|
110231 |
3167 |
GK/Jcl |
serum amylase activity level |
control condition |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood amylase amount |
male |
154 days
| 7 |
718.9 |
U/l |
14.0 |
37.04 |
blood enzyme activity assay |
0.0 |
|
0 |
|
110235 |
3167 |
GK/Jcl |
serum lipase activity level |
control condition |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood lipase amount |
male |
154 days
| 7 |
1022.4 |
IU/l |
54.8 |
144.99 |
blood enzyme activity assay |
0.0 |
|
0 |
|
110239 |
3167 |
GK/Jcl |
body weight |
control condition |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
body mass |
male |
154 days
| 7 |
339.0 |
g |
7.12 |
18.84 |
body measuring method |
0.0 |
|
0 |
|
110207 |
3167 |
GK/Jcl |
serum glucagon-like peptide 1 level |
fasting |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood glucagon-like peptide amount |
male |
154 days
| 7 |
21.5 |
pg/ml |
3.55 |
9.39 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
110223 |
3167 |
GK/Jcl |
blood glucose level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) then fasting (for 12 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
52 days
| 6 |
101.71 |
mg/dl |
3.08 |
7.54 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103931 |
2884 |
GK/Jcl |
heart left ventricle weight |
Omacor (400 mg/kg/d) (for 56 days) |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
heart left ventricle mass |
male |
84 days
| 8 |
0.69 |
g |
0.01 |
0.04 |
post excision weight measurement |
0.0 |
|
0 |
|
103066 |
2785 |
GK/Jcl |
heart left ventricle weight to body weight ratio |
standard diet |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
heart left ventricle mass |
male |
84 days
| 8 |
1.95 |
mg/g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
103069 |
2785 |
GK/Jcl |
blood glucose level |
standard diet |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood glucose amount |
male |
84 days
| 8 |
478.26 |
mg/dl |
23.74 |
67.14 |
blood glucose analysis |
0.0 |
|
0 |
|
103073 |
2785 |
GK/Jcl |
blood triglyceride level |
standard diet |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood triglyceride amount |
male |
84 days
| 8 |
107.08 |
mg/dl |
9.07 |
25.66 |
blood triglyceride analysis |
0.0 |
|
0 |
|
103077 |
2785 |
GK/Jcl |
blood triglyceride level |
Omacor (400 mg/kg/d) (for 56 days) |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood triglyceride amount |
male |
84 days
| 8 |
79.65 |
mg/dl |
8.45 |
23.89 |
blood triglyceride analysis |
0.0 |
|
0 |
|
103078 |
2785 |
GK/Jcl |
blood glucose level |
controlled hesperidin content diet (1 %) then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
24 days
| 6 |
111.5 |
mg/dl |
3.29 |
8.06 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103914 |
2884 |
GK/Jcl |
blood glucose level |
controlled hesperidin content diet (1 %) (for 14 days) then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
38 days
| 6 |
99.85 |
mg/dl |
1.8 |
4.41 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103922 |
2884 |
GK/Jcl |
blood glucose level |
control condition then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
52 days
| 6 |
130.71 |
mg/dl |
6.23 |
15.26 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103929 |
2884 |
GK/Jcl |
food intake rate |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
eating behavior trait |
male |
52 days
| 6 |
11.12 |
g/d |
0.28 |
0.69 |
food intake measuring method |
0.0 |
|
0 |
|
103933 |
2884 |
GK/Jcl |
serum hesperetin level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood flavanone amount |
male |
52 days
| 6 |
35.18 |
umol/l |
3.68 |
9.01 |
high-performance liquid chromatography |
0.0 |
|
0 |
|
103949 |
2884 |
GK/Jcl |
calculated liver glutathione level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver glutathione amount |
male |
52 days
| 6 |
528.9 |
umol/min/mg |
32.17 |
78.8 |
enzyme or transport activity assay |
0.0 |
|
0 |
|
103953 |
2884 |
GK/Jcl |
liver glucokinase level |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver glucokinase activity |
male |
52 days
| 6 |
339.71 |
umol/min/mg |
28.52 |
69.86 |
enzyme or transport activity assay |
0.0 |
|
0 |
|
103956 |
2884 |
GK/Jcl |
liver glucokinase level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver glucokinase activity |
male |
52 days
| 6 |
401.11 |
umol/min/mg |
25.41 |
62.24 |
enzyme or transport activity assay |
0.0 |
|
0 |
|
103957 |
2884 |
GK/Jcl |
serum triglyceride level |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood triglyceride amount |
male |
52 days
| 6 |
56.48 |
mg/dl |
5.56 |
13.62 |
serum triglyceride analysis |
0.0 |
|
0 |
|
103960 |
2884 |
GK/Jcl |
serum total cholesterol level |
vildagliptin (30 mg/kg/d) (for 106 days) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood cholesterol amount |
male |
154 days
| 7 |
37.84 |
mg/dl |
1.54 |
4.09 |
solid phase colorimetry |
0.0 |
|
0 |
|
110232 |
3167 |
GK/Jcl |
blood total cholesterol level |
standard diet |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood cholesterol amount |
male |
84 days
| 8 |
83.01 |
mg/dl |
0.96 |
2.7 |
blood cholesterol analysis |
0.0 |
|
0 |
|
103081 |
2785 |
GK/Jcl |
body weight |
Omacor (400 mg/kg/d) (for 56 days) |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
body mass |
male |
84 days
| 8 |
342.0 |
g |
4.95 |
14.0 |
body weighing method |
0.0 |
|
0 |
|
103058 |
2785 |
GK/Jcl |
blood glucose level |
Omacor (400 mg/kg/d) (for 56 days) |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood glucose amount |
male |
84 days
| 8 |
388.26 |
mg/dl |
27.37 |
77.4 |
blood glucose analysis |
0.0 |
|
0 |
|
103074 |
2785 |
GK/Jcl |
blood total cholesterol level |
Omacor (400 mg/kg/d) (for 56 days) |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
blood cholesterol amount |
male |
84 days
| 8 |
76.83 |
mg/dl |
2.18 |
6.18 |
blood cholesterol analysis |
0.0 |
|
0 |
|
103082 |
2785 |
GK/Jcl |
body weight |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
body mass |
male |
24 days
| 6 |
53.67 |
g |
1.48 |
3.63 |
body weighing method |
0.0 |
|
0 |
|
103905 |
2884 |
GK/Jcl |
body weight |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
body mass |
male |
24 days
| 6 |
52.81 |
g |
1.57 |
3.85 |
body weighing method |
0.0 |
|
0 |
|
103907 |
2884 |
GK/Jcl |
blood glucose level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 7 days) then fasting (for 12 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
31 days
| 6 |
84.14 |
mg/dl |
2.38 |
5.83 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103919 |
2884 |
GK/Jcl |
blood glucose level |
controlled hesperidin content diet (1 %) (for 21 days) then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
45 days
| 6 |
127.36 |
mg/dl |
4.77 |
11.68 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103926 |
2884 |
GK/Jcl |
food intake rate |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
eating behavior trait |
male |
52 days
| 6 |
11.66 |
g/d |
0.35 |
0.86 |
food intake measuring method |
0.0 |
|
0 |
|
103935 |
2884 |
GK/Jcl |
serum adiponectin level |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood adiponectin amount |
male |
52 days
| 6 |
10.38 |
ng/ml |
1.62 |
3.97 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
103941 |
2884 |
GK/Jcl |
serum adiponectin level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood adiponectin amount |
male |
52 days
| 6 |
22.3 |
ng/ml |
1.65 |
4.04 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
103943 |
2884 |
GK/Jcl |
serum high density lipoprotein cholesterol level to serum total cholesterol level ratio |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood cholesterol amount |
male |
52 days
| 6 |
0.61 |
null |
0.02 |
0.05 |
liquid phase colorimetry |
0.0 |
|
0 |
|
103967 |
2884 |
GK/Jcl |
liver triglyceride level |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver triglyceride amount |
male |
52 days
| 6 |
11.37 |
mg/g |
1.3 |
3.18 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
103972 |
2884 |
GK/Jcl |
liver triglyceride level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver triglyceride amount |
male |
52 days
| 6 |
9.41 |
mg/g |
0.8 |
1.96 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
103973 |
2884 |
GK/Jcl |
liver cholesterol level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver cholesterol amount |
male |
52 days
| 6 |
1.67 |
mg/g |
0.06 |
0.15 |
liquid phase colorimetry |
0.0 |
|
0 |
|
103977 |
2884 |
GK/Jcl |
serum lipase activity level |
vildagliptin (30 mg/kg/d) (for 106 days) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood lipase amount |
male |
154 days
| 7 |
737.1 |
IU/l |
64.6 |
170.92 |
blood enzyme activity assay |
0.0 |
|
0 |
|
110240 |
3167 |
GK/Jcl |
plasma glucose level |
fasting |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood glucose amount |
male |
154 days
| 7 |
126.9 |
mg/dl |
20.16 |
53.34 |
plasma glucose analysis |
0.0 |
|
0 |
|
110211 |
3167 |
GK/Jcl |
plasma glucose level |
vildagliptin (30 mg/kg/d) (for 106 days) then fasting |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood glucose amount |
male |
154 days
| 7 |
110.7 |
mg/dl |
4.68 |
12.38 |
plasma glucose analysis |
0.0 |
|
0 |
|
110212 |
3167 |
GK/Jcl |
body weight |
standard diet |
Radosinska J, et al., Physiol Res. 2015;64(6):795-806. Epub 2015 Oct 8. |
body mass |
male |
84 days
| 8 |
353.0 |
g |
7.07 |
20.0 |
body weighing method |
0.0 |
|
0 |
|
103057 |
2785 |
GK/Jcl |
body weight |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
body mass |
male |
24 days
| 6 |
166.41 |
g |
2.36 |
5.78 |
body weighing method |
0.0 |
|
0 |
|
103911 |
2884 |
GK/Jcl |
blood glucose level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) then fasting (for 12 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
24 days
| 6 |
108.28 |
mg/dl |
2.44 |
5.98 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103915 |
2884 |
GK/Jcl |
calculated liver glutathione level |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver glutathione amount |
male |
52 days
| 6 |
694.27 |
umol/min/mg |
46.04 |
112.77 |
enzyme or transport activity assay |
0.0 |
|
0 |
|
103951 |
2884 |
GK/Jcl |
serum triglyceride level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood triglyceride amount |
male |
52 days
| 6 |
33.78 |
mg/dl |
2.83 |
6.93 |
serum triglyceride analysis |
0.0 |
|
0 |
|
103961 |
2884 |
GK/Jcl |
liver cholesterol level |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver cholesterol amount |
male |
52 days
| 6 |
2.62 |
mg/g |
0.08 |
0.2 |
liquid phase colorimetry |
0.0 |
|
0 |
|
103975 |
2884 |
GK/Jcl |
liver cholesterol level |
controlled hesperidin content diet (1 %) (for 28 days) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
liver cholesterol amount |
male |
52 days
| 6 |
1.82 |
mg/g |
0.13 |
0.32 |
liquid phase colorimetry |
0.0 |
|
0 |
|
103976 |
2884 |
GK/Jcl |
serum triglyceride level |
vildagliptin (30 mg/kg/d) (for 106 days) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood triglyceride amount |
male |
154 days
| 7 |
153.1 |
mg/dl |
13.27 |
35.12 |
solid phase colorimetry |
0.0 |
|
0 |
|
110228 |
3167 |
GK/Jcl |
serum amylase activity level |
vildagliptin (30 mg/kg/d) (for 106 days) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood amylase amount |
male |
154 days
| 7 |
501.1 |
U/l |
42.3 |
111.92 |
blood enzyme activity assay |
0.0 |
|
0 |
|
110236 |
3167 |
GK/Jcl |
body weight |
vildagliptin (30 mg/kg/d) (for 106 days) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
body mass |
male |
154 days
| 7 |
345.0 |
g |
2.35 |
6.22 |
body measuring method |
0.0 |
|
0 |
|
110208 |
3167 |
GK/Jcl |
serum insulin level |
fasting then glucose solution (2 g/kg) (for 0.5 hours) |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood insulin amount |
male |
140 days
| 7 |
0.0 |
mg/dl |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
0.0 |
glucose |
30 |
min |
110219 |
3167 |
GK/Jcl |
serum glucagon-like peptide 1 level |
vildagliptin (30 mg/kg/d) (for 106 days) then fasting |
Mizukami H, et al., Pancreas. 2013 Jul;42(5):786-94. doi: 10.1097/MPA.0b013e318287c9b5. |
blood glucagon-like peptide amount |
male |
154 days
| 7 |
43.1 |
pg/ml |
4.95 |
13.1 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
110224 |
3167 |
GK/Jcl |
body weight |
control condition |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
body mass |
male |
24 days
| 6 |
179.97 |
g |
1.82 |
4.46 |
body weighing method |
0.0 |
|
0 |
|
103909 |
2884 |
GK/Jcl |
blood glucose level |
control condition then fasting (for 0 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
24 days
| 6 |
109.71 |
mg/dl |
2.38 |
5.83 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103913 |
2884 |
GK/Jcl |
blood glucose level |
controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 14 days) then fasting (for 12 hours) |
Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. |
blood glucose amount |
male |
38 days
| 6 |
98.57 |
mg/dl |
1.61 |
3.94 |
blood glucose test strip read by electrochemical glucometer |
0.0 |
|
0 |
|
103923 |
2884 |