KFRS3A/Kyo+/+ |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
70 days
| 6 |
|
210.0 |
g |
8.82 |
21.6 |
whole body digital scale |
|
0 |
|
|
71298 |
21 |
KFRS3A/Kyo+/+ |
plasma glucose level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood glucose amount |
male |
70 days
| 6 |
|
212.0 |
mg/dl |
6.12 |
15.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
84223 |
1498 |
KFRS3A/Kyo+/+ |
plasma potassium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood potassium amount |
male |
70 days
| 6 |
|
3.14 |
mmol/l |
0.06 |
0.15 |
automated blood electrolyte analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
84234 |
1498 |
KFRS3A/Kyo+/+ |
blood eosinophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
eosinophil quantity |
male |
70 days
| 6 |
|
1.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
|
84237 |
1498 |
KFRS3A/Kyo+/+ |
blood segmented neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70 days
| 6 |
|
16.0 |
% |
2.04 |
5.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
segmented neutrophil % |
84239 |
1498 |
KFRS3A/Kyo+/+ |
heart wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70 days
| 6 |
|
0.57 |
g |
0.02 |
0.05 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74785 |
41 |
KFRS3A/Kyo+/+ |
heart weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70 days
| 6 |
|
3.0 |
g/kg |
0.05 |
0.12 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74786 |
41 |
KFRS3A/Kyo+/+ |
liver weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70 days
| 6 |
|
2.99 |
% |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74790 |
41 |
KFRS3A/Kyo+/+ |
lung weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70 days
| 6 |
|
0.44 |
% |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74788 |
41 |
KFRS3A/Kyo+/+ |
liver wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70 days
| 6 |
|
5.65 |
g |
0.23 |
0.56 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74789 |
41 |
KFRS3A/Kyo+/+ |
heart rate |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
heart pumping trait |
male |
56 days-70 days |
6 |
serial mean |
424.0 |
beats/min |
12.25 |
30.0 |
tail cuff photoplethysmography |
|
0 |
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
75552 |
14 |
KFRS3A/Kyo+/+ |
plasma chloride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood chloride amount |
male |
70 days
| 6 |
|
98.0 |
mmol/l |
0.41 |
1.0 |
automated blood electrolyte analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
84235 |
1498 |
KFRS3A/Kyo+/+ |
total plasma calcium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood calcium amount |
male |
70 days
| 6 |
|
9.1 |
mg/dl |
0.2 |
0.5 |
automated blood electrolyte analysis |
|
0 |
Hitachi, model 7170 |
|
84232 |
1498 |
KFRS3A/Kyo+/+ |
white blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70 days
| 6 |
|
6.4 |
x 1000 cells/ul |
0.24 |
0.6 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
84215 |
1498 |
KFRS3A/Kyo+/+ |
plasma aspartate aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood aspartate transaminase amount |
male |
70 days
| 6 |
|
71.0 |
U/l |
2.04 |
5.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
84217 |
1498 |
KFRS3A/Kyo+/+ |
plasma low density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood LDL cholesterol amount |
male |
70 days
| 6 |
|
11.0 |
mg/dl |
0.41 |
1.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
84226 |
1498 |
KFRS3A/Kyo+/+ |
plasma high density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood HDL cholesterol amount |
male |
70 days
| 6 |
|
60.3 |
mg/dl |
1.27 |
3.1 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
84225 |
1498 |
KFRS3A/Kyo+/+ |
plasma phosphate level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood phosphate amount |
male |
70 days
| 6 |
|
4.5 |
mg/dl |
0.33 |
0.8 |
automated blood electrolyte analysis |
|
0 |
Hitachi, model 7170 |
|
84231 |
1498 |
KFRS3A/Kyo+/+ |
brain weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70 days
| 6 |
|
1.04 |
% |
0.02 |
0.06 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74784 |
41 |
KFRS3A/Kyo+/+ |
lung wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70 days
| 6 |
|
0.82 |
g |
0.03 |
0.08 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74787 |
41 |
KFRS3A/Kyo+/+ |
spleen weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70 days
| 6 |
|
0.19 |
% |
0.0 |
0.0 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74796 |
41 |
KFRS3A/Kyo+/+ |
both testes wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70 days
| 6 |
|
2.25 |
g |
0.05 |
0.13 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74797 |
41 |
KFRS3A/Kyo+/+ |
urine potassium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63 days
| 6 |
|
78.7 |
mmol/l |
4.53 |
11.1 |
automated urine analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
96514 |
1662 |
KFRS3A/Kyo+/+ |
plasma alkaline phosphatase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alkaline phosphatase amount |
male |
70 days
| 6 |
|
430.0 |
IU/l |
6.53 |
16.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
84219 |
1498 |
KFRS3A/Kyo+/+ |
timed urine volume |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63 days
| 6 |
|
24.0 |
ml/d |
2.29 |
5.6 |
metabolic cage urine volume measurement method |
|
0 |
|
|
96510 |
1662 |
KFRS3A/Kyo+/+ |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
42 days
| 6 |
|
147.2 |
g |
4.04 |
9.9 |
whole body digital scale |
|
0 |
|
|
71299 |
21 |
KFRS3A/Kyo+/+ |
mean corpuscular hemoglobin concentration |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
33.7 |
g/dl |
0.29 |
0.7 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
84214 |
1498 |
KFRS3A/Kyo+/+ |
plasma albumin to plasma total protein ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70 days
| 6 |
|
2.19 |
null |
0.06 |
0.15 |
automated plasma protein analysis |
|
0 |
Hitachi, model 7170 |
plasma albumin to plasma total protein ratio |
84222 |
1498 |
KFRS3A/Kyo+/+ |
plasma total bilirubin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood bilirubin amount |
male |
70 days
| 6 |
|
0.3 |
mg/dl |
0.04 |
0.1 |
automated plasma analysis |
|
0 |
PMID:15591307 |
total plasma bilirubin level |
84228 |
1498 |
KFRS3A/Kyo+/+ |
plasma sodium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood sodium amount |
male |
70 days
| 6 |
|
142.0 |
mmol/l |
0.45 |
1.1 |
automated blood electrolyte analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
84233 |
1498 |
KFRS3A/Kyo+/+ |
non-specified leukocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
unidentified differential wbc |
84242 |
1498 |
KFRS3A/Kyo+/+ |
both adrenal glands wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70 days
| 6 |
|
59.1 |
mg |
3.92 |
9.6 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74793 |
41 |
KFRS3A/Kyo+/+ |
spleen wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70 days
| 6 |
|
0.36 |
g |
0.01 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74795 |
41 |
KFRS3A/Kyo+/+ |
urine chloride excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63 days
| 6 |
|
398.0 |
uEq/100g/6 hrs |
13.06 |
32.0 |
automated urine analysis |
|
0 |
|
|
96517 |
1662 |
KFRS3A/Kyo+/+ |
systolic blood pressure |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
arterial blood pressure trait |
male |
56 days-70 days |
6 |
serial mean |
105.0 |
mmHg |
5.31 |
13.0 |
tail cuff photoplethysmography |
|
0 |
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
75551 |
14 |
KFRS3A/Kyo+/+ |
plasma albumin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70 days
| 6 |
|
0.4 |
g/l |
0.0 |
0.01 |
automated plasma albumin analysis |
|
0 |
Hitachi, model 7170 |
|
84221 |
1498 |
KFRS3A/Kyo+/+ |
mean corpuscular hemoglobin |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
18.2 |
pg |
0.2 |
0.5 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
84213 |
1498 |
KFRS3A/Kyo+/+ |
plasma urea nitrogen level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood urea nitrogen amount |
male |
70 days
| 6 |
|
10.0 |
mmol/l |
0.64 |
1.57 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
84229 |
1498 |
KFRS3A/Kyo+/+ |
plasma total cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood cholesterol amount |
male |
70 days
| 6 |
|
93.0 |
mg/dl |
1.63 |
4.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
84224 |
1498 |
KFRS3A/Kyo+/+ |
both testes wet weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70 days
| 6 |
|
1.19 |
% |
0.04 |
0.09 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74798 |
41 |
KFRS3A/Kyo+/+ |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
35 days
| 6 |
|
121.2 |
g |
3.43 |
8.4 |
whole body digital scale |
|
0 |
|
|
71300 |
21 |
KFRS3A/Kyo+/+ |
mean corpuscular volume |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte size trait |
male |
70 days
| 6 |
|
54.2 |
fl |
0.41 |
1.0 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
84212 |
1498 |
KFRS3A/Kyo+/+ |
red blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70 days
| 6 |
|
9.19 |
x 10E6 cells/ul |
0.1 |
0.25 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
84209 |
1498 |
KFRS3A/Kyo+/+ |
plasma alanine aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alanine transaminase amount |
male |
70 days
| 6 |
|
28.0 |
U/l |
0.41 |
1.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
84218 |
1498 |
KFRS3A/Kyo+/+ |
plasma creatinine level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood creatinine amount |
male |
70 days
| 6 |
|
0.31 |
mg/dl |
0.04 |
0.1 |
automated plasma creatinine analysis |
|
0 |
Hitachi, model 7170 |
|
84230 |
1498 |
KFRS3A/Kyo+/+ |
brain wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70 days
| 6 |
|
1.96 |
g |
0.04 |
0.1 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74783 |
41 |
KFRS3A/Kyo+/+ |
both kidneys wet weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70 days
| 6 |
|
0.78 |
% |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74792 |
41 |
KFRS3A/Kyo+/+ |
urine potassium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63 days
| 6 |
|
222.0 |
uEq/100g/6 hrs |
8.16 |
20.0 |
automated urine analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
96515 |
1662 |
KFRS3A/Kyo+/+ |
hematocrit |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70 days
| 6 |
|
49.8 |
% |
0.73 |
1.8 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
84211 |
1498 |
KFRS3A/Kyo+/+ |
platelet count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
platelet quantity |
male |
70 days
| 6 |
|
981.0 |
x 1000 /ul |
29.39 |
72.0 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
84216 |
1498 |
KFRS3A/Kyo+/+ |
blood lymphocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
lymphocyte quantity |
male |
70 days
| 6 |
|
83.0 |
% |
2.04 |
5.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
|
84240 |
1498 |
KFRS3A/Kyo+/+ |
urine chloride level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63 days
| 6 |
|
141.0 |
mEq/L |
6.12 |
15.0 |
automated urine analysis |
|
0 |
|
|
96516 |
1662 |
KFRS3A/Kyo+/+ |
body temperature |
specific pathogen-free condition |
NBRP Body Temperature data |
body temperature trait |
male |
56 days-70 days |
6 |
serial mean |
37.9 |
degrees C |
0.04 |
0.1 |
digital rectal thermometry |
|
0 |
|
|
75553 |
22 |
KFRS3A/Kyo+/+ |
blood hemoglobin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
16.7 |
g/dl |
0.24 |
0.6 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
84210 |
1498 |
KFRS3A/Kyo+/+ |
plasma total protein level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood total protein amount |
male |
70 days
| 6 |
|
58.0 |
mg/ml |
0.82 |
2.0 |
automated plasma total protein analysis |
|
0 |
Hitachi, model 7170 |
|
84220 |
1498 |
KFRS3A/Kyo+/+ |
blood basophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
basophil quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
|
84236 |
1498 |
KFRS3A/Kyo+/+ |
blood monocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
monocyte quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
|
84241 |
1498 |
KFRS3A/Kyo+/+ |
both kidneys wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70 days
| 6 |
|
1.47 |
g |
0.05 |
0.13 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74791 |
41 |
KFRS3A/Kyo+/+ |
both adrenal glands weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70 days
| 6 |
|
31.3 |
mg/100g |
1.8 |
4.4 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
74794 |
41 |
KFRS3A/Kyo+/+ |
urine sodium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63 days
| 6 |
|
116.5 |
mmol/l |
2.98 |
7.3 |
automated urine analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
96512 |
1662 |
KFRS3A/Kyo+/+ |
timed urine volume to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63 days
| 6 |
|
0.08 |
ul/min/g |
0.01 |
0.01 |
metabolic cage urine volume measurement method |
|
0 |
|
|
96511 |
1662 |
KFRS3A/Kyo+/+ |
plasma triglyceride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood triglyceride amount |
male |
70 days
| 6 |
|
0.5 |
mmol/l |
0.04 |
0.1 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
84227 |
1498 |
KFRS3A/Kyo+/+ |
blood band neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
band neutrophil % |
84238 |
1498 |
KFRS3A/Kyo+/+ |
urine sodium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63 days
| 6 |
|
0.01 |
uEq/min/g |
0.0 |
0.0 |
automated urine analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
96513 |
1662 |