Phenominer Database Results (134 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Clinical Measurement Notes Experiment Notes Record ID Study ID
SS-Nppbem2Mcwi+/+ body weight controlled sodium content diet (4 %) (for 10 days) PhysGen Knockout data body mass male 70 days-77 days 4 328.0 g 8.6 17.3 whole body digital scale 0 - 43896 441
SS-Nppbem2Mcwi+/+ right kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data kidney mass male 70 days-77 days 4 1.49 g 0.04 0.08 digital scale post excision weight measurement 0 - 44328 441
SS-Nppbem2Mcwi+/+ heart rate control condition (for 222 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 222 days 3 418.0 beats/min 13.0 22.52 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99517 2319
SS-Nppbem2Mcwi+/+ diastolic blood pressure control condition (for 222 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 222 days 3 72.0 mmHg 2.0 3.46 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99529 2319
SS-Nppbem2Mcwi+/+ mean arterial blood pressure control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84 days 2 106.0 mmHg 4.0 5.66 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99531 2319
SS-Nppbem2Mcwi+/+ body weight control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. body mass male 252 days 6 462.0 g 19.0 46.54 body weighing method 0.0 0 99551 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 28 days 5 0.82 mm 0.07 0.16 echocardiography 0.0 0 99563 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 28 days 5 5.7 mm 0.36 0.8 echocardiography 0.0 0 99573 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 252 days 6 7.83 mm 0.3 0.73 echocardiography 0.0 0 99581 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic posterior wall thickness control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 84 days 6 1.72 mm 0.06 0.15 echocardiography 0.0 0 99587 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic posterior wall thickness control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 252 days 6 2.54 mm 0.16 0.39 echocardiography 0.0 0 99591 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 56 days 5 2.51 mm 0.08 0.18 echocardiography 0.0 0 99595 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic diameter control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-systolic diameter male 252 days 6 4.72 mm 0.04 0.1 echocardiography 0.0 0 99611 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic posterior wall thickness control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 28 days 5 1.45 mm 0.1 0.22 echocardiography 0.0 0 99613 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic posterior wall thickness control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 252 days 6 3.77 mm 0.11 0.27 echocardiography 0.0 0 99621 2319
SS-Nppbem2Mcwi+/+ ejection fraction control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. cardiac output trait male 28 days 5 83.2 % 7.2 16.1 echocardiography 0.0 0 99623 2319
SS-Nppbem2Mcwi+/+ ejection fraction control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. cardiac output trait male 56 days 5 85.8 % 2.8 6.26 echocardiography 0.0 0 99625 2319
SS-Nppbem2Mcwi+/+ QT interval control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 84 days 2 45.9 ms 0.2 0.28 electrocardiography 0.0 0 99678 2319
SS-Nppbem2Mcwi+/+ QRS duration control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 84 days 2 21.6 ms 1.9 2.69 electrocardiography 0.0 0 99690 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter controlled sodium content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 98 days 4 8.75 mm 0.66 1.32 echocardiography 0.0 0 99712 2319
SS-Nppbem2Mcwi+/+ serum alanine aminotransferase activity level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood alanine transaminase amount male 252 days 6 60.7 U/l 8.1 19.84 automated serum analysis 0.0 0 99744 2319
SS-Nppbem2Mcwi+/+ mean arterial blood pressure controlled sodium content diet (4 %) (for 13 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 4 1/3 systolic pressure + 2/3 diastolic pressure 134.25 mmHg 5.01 10.01 radiotelemetry carotid artery 0 - 43771 441
SS-Nppbem2Mcwi+/+ urine total protein excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data total urine protein amount male 70 days-77 days 4 98.46 mg/d 5.44 10.88 automated urine analysis 0 - 43958 441
SS-Nppbem2Mcwi+/+ urine albumin excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine albumin amount male 70 days-77 days 4 33.82 mg/d 4.67 9.33 automated urine analysis 0 - 44266 441
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic posterior wall thickness control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart left ventricle posterior wall thickness female 252 days 4 1.95 mm 0.1 0.2 echocardiography 0.0 0 101645 2621
SS-Nppbem2Mcwi+/+ systolic blood pressure control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168 days 5 114.0 mmHg 11.0 24.6 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99521 2319
SS-Nppbem2Mcwi+/+ diastolic blood pressure control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84 days 2 89.0 mmHg 4.0 5.66 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99525 2319
SS-Nppbem2Mcwi+/+ systolic blood pressure control condition (for 222 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 222 days 3 123.0 mmHg 3.0 5.2 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99523 2319
SS-Nppbem2Mcwi+/+ diastolic blood pressure control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168 days 5 69.0 mmHg 7.0 15.65 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99527 2319
SS-Nppbem2Mcwi+/+ body weight control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. body mass male 56 days 5 267.0 g 5.0 11.18 body weighing method 0.0 0 99545 2319
SS-Nppbem2Mcwi+/+ heart rate control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 252 days 6 342.0 beats/min 5.0 12.25 echocardiography 0.0 0 99561 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 56 days 5 1.26 mm 0.07 0.16 echocardiography 0.0 0 IVSd 99565 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 28 days 5 1.82 mm 0.23 0.51 echocardiography 0.0 0 99593 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 252 days 6 3.81 mm 0.16 0.39 echocardiography 0.0 0 99601 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic diameter control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-systolic diameter male 56 days 5 4.21 mm 0.41 0.92 echocardiography 0.0 0 99605 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic diameter control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-systolic diameter male 84 days 6 3.98 mm 0.16 0.39 echocardiography 0.0 0 99607 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic diameter control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-systolic diameter male 168 days 5 4.51 mm 0.13 0.29 echocardiography 0.0 0 99609 2319
SS-Nppbem2Mcwi+/+ heart left ventricle weight control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle mass male 56 days 5 1.16 g 0.04 0.09 echocardiography 0.0 0 99670 2319
SS-Nppbem2Mcwi+/+ QRS duration control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 252 days 3 29.4 ms 7.2 12.47 electrocardiography 0.0 0 99694 2319
SS-Nppbem2Mcwi+/+ RR interval control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 252 days 3 158.0 ms 16.0 27.71 electrocardiography 0.0 0 99700 2319
SS-Nppbem2Mcwi+/+ serum total bilirubin level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood bilirubin amount male 252 days 6 0.27 mg/dl 0.1 0.24 automated serum analysis 0.0 0 99746 2319
SS-Nppbem2Mcwi+/+ blood urea nitrogen level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood urea nitrogen amount male 252 days 6 19.5 mg/dl 3.5 8.57 blood urea analysis 0.0 0 99748 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic posterior wall thickness control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart left ventricle posterior wall thickness female 252 days 4 3.08 mm 0.09 0.18 echocardiography 0.0 0 101651 2621
SS-Nppbem2Mcwi+/+ heart rate control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart pumping trait female 252 days 4 321.0 beats/min 10.0 20.0 echocardiography 0.0 0 101659 2621
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic diameter controlled sodium content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-systolic diameter male 98 days 4 5.26 mm 0.65 1.3 echocardiography 0.0 0 99718 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic posterior wall thickness controlled sodium content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 98 days 4 2.51 mm 0.23 0.46 echocardiography 0.0 0 99720 2319
SS-Nppbem2Mcwi+/+ heart left ventricle weight controlled sodium chloride content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle mass male 98 days 4 1.47 g 0.11 0.22 echocardiography 0.0 0 99726 2319
SS-Nppbem2Mcwi+/+ red blood cell count control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. erythrocyte quantity male 252 days 6 10.12 x 10E6 cells/ul 0.28 0.69 automated blood cell counting method 0.0 0 99732 2319
SS-Nppbem2Mcwi+/+ platelet count control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. platelet quantity male 252 days 6 673.2 x 1000 /ul 63.5 155.54 automated platelet count test 0.0 0 99738 2319
SS-Nppbem2Mcwi+/+ serum albumin level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood albumin amount male 252 days 6 1.43 g/dl 0.08 0.2 automated serum albumin analysis 0.0 0 99740 2319
SS-Nppbem2Mcwi+/+ heart left ventricle weight control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart left ventricle mass female 252 days 4 1.46 g 0.02 0.04 echocardiography 0.0 0 101657 2621
SS-Nppbem2Mcwi+/+ heart rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 4 341.5 beats/min 8.18 16.36 radiotelemetry carotid artery 0 - 44019 441
SS-Nppbem2Mcwi+/+ heart rate controlled sodium content diet (4 %) (for 12 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 4 357.0 beats/min 13.72 27.43 radiotelemetry carotid artery 0 - 44575 441
SS-Nppbem2Mcwi+/+ heart interventricular end-diastolic septal wall thickness control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart ventricle septum thickness female 252 days 4 1.98 mm 0.04 0.08 echocardiography 0.0 0 IVSd 101641 2621
SS-Nppbem2Mcwi+/+ heart rate control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 168 days 5 395.0 beats/min 54.0 120.75 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99515 2319
SS-Nppbem2Mcwi+/+ pulse pressure control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84 days 2 36.0 mmHg 1.0 1.41 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99537 2319
SS-Nppbem2Mcwi+/+ body weight control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. body mass male 84 days 6 398.0 g 16.0 39.19 body weighing method 0.0 0 99547 2319
SS-Nppbem2Mcwi+/+ body weight control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. body mass male 168 days 5 438.0 g 21.0 46.96 body weighing method 0.0 0 99549 2319
SS-Nppbem2Mcwi+/+ heart rate control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 56 days 5 367.0 beats/min 19.0 42.49 echocardiography 0.0 0 99555 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 84 days 6 7.53 mm 0.07 0.17 echocardiography 0.0 0 99577 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 56 days 5 8.11 mm 0.35 0.78 echocardiography 0.0 0 99575 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 84 days 6 2.85 mm 0.13 0.32 echocardiography 0.0 0 99597 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic diameter control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-systolic diameter male 28 days 5 3.09 mm 0.61 1.36 echocardiography 0.0 0 99603 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic posterior wall thickness control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 84 days 6 2.9 mm 0.07 0.17 echocardiography 0.0 0 99617 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic posterior wall thickness control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 168 days 5 3.29 mm 0.13 0.29 echocardiography 0.0 0 99619 2319
SS-Nppbem2Mcwi+/+ heart left ventricle weight control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle mass male 84 days 6 1.34 g 0.04 0.1 echocardiography 0.0 0 99672 2319
SS-Nppbem2Mcwi+/+ QT interval control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 168 days 5 48.0 ms 10.2 22.81 electrocardiography 0.0 0 99680 2319
SS-Nppbem2Mcwi+/+ PR interval control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 84 days 2 46.4 ms 0.0 0.0 electrocardiography 0.0 0 99684 2319
SS-Nppbem2Mcwi+/+ RR interval control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 84 days 2 152.0 ms 8.0 11.31 electrocardiography 0.0 0 99696 2319
SS-Nppbem2Mcwi+/+ heart rate variability control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 168 days 5 undefined 30.4 ms 9.7 21.69 electrocardiography 0.0 0 99704 2319
SS-Nppbem2Mcwi+/+ serum creatinine level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood creatinine amount male 252 days 6 0.3 mg/dl 0.1 0.24 serum creatinine analysis 0.0 0 99750 2319
SS-Nppbem2Mcwi+/+ blood glucose level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood glucose amount male 252 days 6 183.2 mg/dl 37.8 92.59 blood glucose analysis 0.0 0 99752 2319
SS-Nppbem2Mcwi+/+ heart left ventricle fractional shortening control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 56 days 5 48.0 % 3.9 8.72 echocardiography 0.0 0 99635 2319
SS-Nppbem2Mcwi+/+ heart left ventricle fractional shortening control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 84 days 6 47.0 % 2.1 5.14 echocardiography 0.0 0 99637 2319
SS-Nppbem2Mcwi+/+ hematocrit control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. erythrocyte quantity male 252 days 6 52.3 % 1.8 4.41 automated hematology analysis 0.0 0 99736 2319
SS-Nppbem2Mcwi+/+ left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data kidney mass male 70 days-77 days 4 1.43 g 0.06 0.13 digital scale post excision weight measurement 0 - 44451 441
SS-Nppbem2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70 days-77 days 4 8.93 mEq/d 1.6 3.19 automated urine analysis 0 - 44204 441
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic diameter control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart left ventricle end-systolic diameter female 252 days 4 3.66 mm 0.15 0.3 echocardiography 0.0 0 101649 2621
SS-Nppbem2Mcwi+/+ mean arterial blood pressure controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 4 1/3 systolic pressure + 2/3 diastolic pressure 132.0 mmHg 2.74 5.48 radiotelemetry carotid artery 0 - 43833 441
SS-Nppbem2Mcwi+/+ urine creatinine excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine creatinine amount male 70 days-77 days 4 12.41 mg/d 0.94 1.88 automated urine analysis 0 - 44142 441
SS-Nppbem2Mcwi+/+ heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data heart mass male 70 days-77 days 4 1.13 g 0.03 0.07 digital scale post excision weight measurement 0 - 44513 441
SS-Nppbem2Mcwi+/+ heart rate controlled sodium content diet (4 %) (for 11 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 4 361.25 beats/min 18.22 36.45 radiotelemetry carotid artery 0 - 44636 441
SS-Nppbem2Mcwi+/+ systolic blood pressure control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84 days 2 126.0 mmHg 5.0 7.07 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99519 2319
SS-Nppbem2Mcwi+/+ mean arterial blood pressure control condition (for 222 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 222 days 3 94.0 mmHg 2.0 3.46 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99535 2319
SS-Nppbem2Mcwi+/+ pulse pressure control condition (for 222 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 222 days 3 52.0 mmHg 1.0 1.73 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99541 2319
SS-Nppbem2Mcwi+/+ pulse pressure control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168 days 5 45.0 mmHg 8.0 17.89 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99539 2319
SS-Nppbem2Mcwi+/+ body weight control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. body mass male 28 days 5 96.0 g 7.0 15.65 body weighing method 0.0 0 99543 2319
SS-Nppbem2Mcwi+/+ heart rate control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 28 days 5 382.0 beats/min 16.0 35.78 echocardiography 0.0 0 99553 2319
SS-Nppbem2Mcwi+/+ heart rate control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 84 days 6 368.0 beats/min 13.0 31.84 echocardiography 0.0 0 99557 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 168 days 5 1.84 mm 0.09 0.2 echocardiography 0.0 0 99569 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 168 days 5 8.48 mm 0.08 0.18 echocardiography 0.0 0 99579 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 168 days 5 3.26 mm 0.08 0.18 echocardiography 0.0 0 99599 2319
SS-Nppbem2Mcwi+/+ ejection fraction control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. cardiac output trait male 168 days 5 85.0 % 1.0 2.24 echocardiography 0.0 0 99629 2319
SS-Nppbem2Mcwi+/+ QT interval control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 252 days 3 43.0 ms 2.7 4.68 electrocardiography 0.0 0 99682 2319
SS-Nppbem2Mcwi+/+ PR interval control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 252 days 3 44.8 ms 15.3 26.5 electrocardiography 0.0 0 99688 2319
SS-Nppbem2Mcwi+/+ RR interval control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 168 days 5 189.0 ms 19.0 42.49 electrocardiography 0.0 0 99698 2319
SS-Nppbem2Mcwi+/+ heart rate variability control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 84 days 2 undefined 27.8 ms 0.1 0.14 electrocardiography 0.0 0 HRV 99702 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic posterior wall thickness controlled sodium content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 98 days 4 1.58 mm 0.12 0.24 echocardiography 0.0 0 99714 2319
SS-Nppbem2Mcwi+/+ ejection fraction control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. cardiac output trait female 252 days 4 87.0 % 1.8 3.6 echocardiography 0.0 0 101653 2621
SS-Nppbem2Mcwi+/+ ejection fraction control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. cardiac output trait male 252 days 6 74.8 % 2.7 6.61 echocardiography 0.0 0 99631 2319
SS-Nppbem2Mcwi+/+ heart left ventricle fractional shortening control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 168 days 5 46.8 % 1.2 2.68 echocardiography 0.0 0 99639 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness controlled sodium content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 98 days 4 2.91 mm 0.13 0.26 echocardiography 0.0 0 IVSs 99716 2319
SS-Nppbem2Mcwi+/+ ejection fraction controlled sodium chloride content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. cardiac output trait male 98 days 4 77.3 % 3.09 6.18 echocardiography 0.0 0 99722 2319
SS-Nppbem2Mcwi+/+ heart left ventricle fractional shortening controlled sodium content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 98 days 4 41.7 % 2.62 5.24 echocardiography 0.0 0 99724 2319
SS-Nppbem2Mcwi+/+ white blood cell count control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. leukocyte quantity male 252 days 6 8.1 x 1000 cells/ul 0.91 2.23 blood cell counting method 0.0 0 99730 2319
SS-Nppbem2Mcwi+/+ blood hemoglobin level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood hemoglobin amount male 252 days 6 16.42 g/dl 0.24 0.59 blood hemoglobin analysis 0.0 0 99734 2319
SS-Nppbem2Mcwi+/+ heart left ventricle fractional shortening control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 28 days 5 46.0 % 8.4 18.78 echocardiography 0.0 0 99633 2319
SS-Nppbem2Mcwi+/+ heart left ventricle fractional shortening control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 252 days 6 39.0 % 2.2 5.39 echocardiography 0.0 0 99641 2319
SS-Nppbem2Mcwi+/+ serum alkaline phosphatase activity level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood alkaline phosphatase amount male 252 days 6 137.7 U/l 5.7 13.96 automated serum analysis 0.0 0 99742 2319
SS-Nppbem2Mcwi+/+ heart rate controlled sodium content diet (4 %) (for 13 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 4 360.75 beats/min 7.53 15.06 radiotelemetry carotid artery 0 - 43709 441
SS-Nppbem2Mcwi+/+ mean arterial blood pressure controlled sodium content diet (4 %) (for 11 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 4 1/3 systolic pressure + 2/3 diastolic pressure 129.0 mmHg 5.55 11.11 radiotelemetry carotid artery 0 - 44081 441
SS-Nppbem2Mcwi+/+ mean arterial blood pressure controlled sodium content diet (4 %) (for 12 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 4 1/3 systolic pressure + 2/3 diastolic pressure 133.25 mmHg 3.68 7.37 radiotelemetry carotid artery 0 - 44390 441
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart ventricle septum thickness female 252 days 4 3.51 mm 0.07 0.14 echocardiography 0.0 0 IVSs 101647 2621
SS-Nppbem2Mcwi+/+ heart rate control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 84 days 2 413.0 beats/min 11.0 15.56 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99513 2319
SS-Nppbem2Mcwi+/+ mean arterial blood pressure control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168 days 5 88.0 mmHg 8.0 17.89 intra-aortic abdominal radiotelemetry via abdominal aorta cannulation 0.0 0 99533 2319
SS-Nppbem2Mcwi+/+ heart rate control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 168 days 5 337.0 beats/min 13.0 29.07 echocardiography 0.0 0 99559 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 84 days 6 1.7 mm 0.1 0.24 echocardiography 0.0 0 99567 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-systolic septal wall thickness control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 252 days 6 2.41 mm 0.14 0.34 echocardiography 0.0 0 99571 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic posterior wall thickness control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 56 days 5 1.28 mm 0.17 0.38 echocardiography 0.0 0 99585 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic posterior wall thickness control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 28 days 5 0.9 mm 0.05 0.11 echocardiography 0.0 0 99583 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic posterior wall thickness control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 168 days 5 2.02 mm 0.08 0.18 echocardiography 0.0 0 99589 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-systolic posterior wall thickness control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle posterior wall thickness male 56 days 5 2.35 mm 0.39 0.87 echocardiography 0.0 0 99615 2319
SS-Nppbem2Mcwi+/+ ejection fraction control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. cardiac output trait male 84 days 6 83.3 % 2.0 4.9 echocardiography 0.0 0 99627 2319
SS-Nppbem2Mcwi+/+ heart left ventricle weight control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle mass male 168 days 5 1.64 g 0.02 0.04 echocardiography 0.0 0 99674 2319
SS-Nppbem2Mcwi+/+ heart left ventricle weight control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle mass male 252 days 6 1.94 g 0.06 0.15 echocardiography 0.0 0 99676 2319
SS-Nppbem2Mcwi+/+ PR interval control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 168 days 5 48.0 ms 6.8 15.21 electrocardiography 0.0 0 99686 2319
SS-Nppbem2Mcwi+/+ QRS duration control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart electrical impulse conduction trait male 168 days 5 27.0 ms 5.7 12.75 electrocardiography 0.0 0 99692 2319
SS-Nppbem2Mcwi+/+ heart rate variability control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 252 days 3 undefined 26.5 ms 8.8 15.24 electrocardiography 0.0 0 99706 2319
SS-Nppbem2Mcwi+/+ heart interventricular end-diastolic septal wall thickness controlled sodium content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart ventricle septum thickness male 98 days 4 1.67 mm 0.09 0.18 echocardiography 0.0 0 99710 2319
SS-Nppbem2Mcwi+/+ heart left ventricle fractional shortening control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart left ventricle end-diastolic diameter female 252 days 4 49.5 % 2.2 4.4 echocardiography 0.0 0 101655 2621
SS-Nppbem2Mcwi+/+ heart left ventricle weight control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle mass male 28 days 5 0.79 g 0.01 0.02 echocardiography 0.0 0 99643 2319
SS-Nppbem2Mcwi+/+ heart rate controlled sodium chloride content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart pumping trait male 98 days 4 420.0 beats/min 7.0 14.0 echocardiography 0.0 0 99728 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart left ventricle end-diastolic diameter female 252 days 4 7.28 mm 0.11 0.22 echocardiography 0.0 0 101643 2621
SS-Nppbem2Mcwi+/+ serum total protein level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood total protein amount male 252 days 6 7.1 g/dl 0.2 0.49 serum total protein analysis 0.0 0 99754 2319