WAG/RijCmcr |
dose of irradiation that is fatal to 50% of the total study population |
partial body irradiation (10-12.75 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
life span trait |
male |
169 days-176 days |
72 |
11.5 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
120 |
days |
probit analysis |
95% CI [10.7, 12.3] - LD50 nephropathy |
108600 |
3125 |
WAG/RijCmcr |
percentage of study population developing radiation-induced bone marrow disease during a period of time |
total body irradiation (7 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
bone marrow cell integrity trait |
male |
86 days
| 37 |
62.0 |
% |
|
|
probit analysis estimate |
0.0 |
radiation |
30 |
days |
probit analysis |
percentage of study population developing radiation-induced bone marrow disease during a period of time (CMO:0003723) |
108588 |
3125 |
WAG/RijCmcr |
dose of whole thorax lung irradiation at which breathing rate increases for 50% of the total study population |
whole thorax lung irradiation (13-16.5 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
lung integrity trait |
male |
133 days-140 days |
55 |
15.3 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
56 |
days |
probit analysis |
dose of whole thorax lung irradiation at which breathing rate increases for 50% of the total study population (CMO:0003704) |
108592 |
3125 |
WAG/RijCmcr |
dose of irradiation that is fatal to 50% of the total study population |
partial-body irradiation with 5% bone marrow sparing (12.25-13 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
life span trait |
male |
56 days-63 days |
105 |
13.7 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
7 |
days |
probit analysis |
95% CI [12.9, 14.4] - GI |
108578 |
3125 |
WAG/RijCmcr |
dose of irradiation that is fatal to 50% of the total study population |
partial body irradiation (10.5-13 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
life span trait |
female |
183 days-190 days |
37 |
12.1 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
120 |
days |
probit analysis |
95% CI [11.6, 12.6] - LD50 nephropathy |
108599 |
3125 |
WAG/RijCmcr |
dose of irradiation that is fatal to 50% of the total study population |
whole thorax lung irradiation (13-16.5 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
life span trait |
male |
167 days-174 days |
55 |
15.2 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
90 |
days |
probit analysis |
95% CI [14.8, 15.5] - pneumotitis |
108590 |
3125 |
WAG/RijCmcr |
dose of irradiation that is fatal to 50% of the total study population |
leg-out partial body irradiation (11-13 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
life span trait |
female |
84 days-91 days |
44 |
12.9 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
7 |
days |
probit analysis |
|
108577 |
3125 |
WAG/RijCmcr |
dose of irradiation that is fatal to 50% of the total study population |
whole thorax lung irradiation (11-13 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
life span trait |
female |
153 days-160 days |
456 |
12.7 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
90 |
days |
probit analysis |
95% CI [12.6, 12.8] - pneumotitis |
108589 |
3125 |
WAG/RijCmcr |
dose of irradiation that is fatal to 50% of the total study population |
total body irradiation (7-8 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
life span trait |
female |
107 days-114 days |
103 |
7.0 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
30 |
days |
probit analysis |
|
108587 |
3125 |
WAG/RijCmcr |
percentage of study population developing radiation pneumonitis during a period of time |
partial-body irradiation with 5% bone marrow sparing (12.75-13 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
lung integrity trait |
male |
56 days-63 days |
13 |
38.0 |
% |
|
|
probit analysis estimate |
0.0 |
|
0 |
|
probit analysis |
|
110377 |
3125 |
WAG/RijCmcr |
dose of irradiation that is fatal to 50% of the total study population |
leg-out partial body irradiation (11.5-13 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
life span trait |
female |
183 days-190 days |
37 |
12.5 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
94 |
days |
probit analysis |
|
110167 |
3125 |
WAG/RijCmcr |
dose of whole thorax lung irradiation at which breathing rate increases for 50% of the total study population |
whole thorax lung irradiation (11-14 Gy) |
Fish BL, et al., Int J Radiat Biol. 2020 Jan;96(1):81-92. doi: 10.1080/09553002.2018.1554921. Epub 2019 Jan 14. |
lung integrity trait |
female |
105 days-112 days |
28 |
11.8 |
Gy |
|
|
probit analysis estimate |
0.0 |
radiation |
42 |
days |
probit analysis |
dose of whole thorax lung irradiation at which breathing rate increases for 50% of the total study population (CMO:0003704) |
108591 |
3125 |