DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
10 |
70.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
68198 |
829 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 27 |
14.0 |
d |
1.06 |
5.5 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
70194 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 16 |
33.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
0 |
|
from 8 to 40 days |
|
|
69385 |
892 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 28 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 21 |
18.7 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
0 |
|
from 8 to 28 days |
|
|
69418 |
892 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (0.09 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
0 |
20.0 |
d |
|
8.5 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
69501 |
837 |
DA/ZtmKini |
inguinal lymph node wet weight to body weight ratio |
control condition |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
inguinal lymph node mass |
male |
0 days
| 8 |
0.15 |
g/kg |
0.01 |
0.02 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
84928 |
1301 |
DA/ZtmKini |
plasma orosomucoid 1 level |
control condition |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
orosomucoid 1 amount |
male |
0 days
| 8 |
93.0 |
mg/l |
8.13 |
23.0 |
radial immunodiffusion assay |
|
0.0 |
|
0 |
|
|
|
|
84934 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
male |
0 days
| 24 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
84465 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
male |
0 days
| 24 |
14.6 |
d |
1.39 |
6.8 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
84467 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 15 |
14.9 |
d |
1.52 |
5.9 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
84471 |
1301 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
8 |
13.0 |
d |
1.8 |
5.09 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
68197 |
829 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
11 |
14.9 |
d |
1.03 |
3.4 |
in vivo visual assessment |
|
0.0 |
intradermal injection |
0 |
|
from p.i. day 7 |
|
|
68133 |
839 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
8 |
16.2 |
d |
0.92 |
2.6 |
in vivo visual assessment |
|
0.0 |
intradermal injection |
0 |
|
from p.i. day 7 |
|
|
68707 |
839 |
DA/ZtmKini |
liver weight to body weight ratio |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
liver mass |
male |
0 days
| 8 |
28.96 |
g/kg |
0.64 |
1.8 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
84933 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
16 |
87.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
67853 |
829 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
8 |
16.4 |
d |
2.6 |
7.35 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
68200 |
829 |
DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
8 |
87.5 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
|
68717 |
839 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
11 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
|
68132 |
839 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
10 |
80.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
|
68706 |
839 |
DA/ZtmKini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103 days-131 days |
10 |
3.5 |
% |
1.49 |
4.7 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
|
68708 |
839 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65 days-112 days |
22 |
15.8 |
d |
1.9 |
8.9 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
69489 |
837 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (0.09 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91 days-112 days |
0 |
89.0 |
% |
|
33.0 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
visual observation |
|
|
69497 |
837 |
DA/ZtmKini |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
total life span |
both |
63 days-150 days |
20 |
0.0 |
% |
|
|
necropsy |
|
0.0 |
intradermal injection |
0 |
|
visual observation |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time (CMO:0003802) |
|
68125 |
838 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
12 |
19.7 |
d |
2.48 |
8.6 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
69376 |
837 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 37 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 28 |
26.5 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
0 |
|
from 8 to 37 days |
|
|
69380 |
892 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 10 |
23.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
|
69411 |
892 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 15 |
93.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
84469 |
1301 |
DA/ZtmKini |
spleen weight to body weight ratio |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
spleen mass |
male |
0 days
| 8 |
0.18 |
% |
0.0 |
0.01 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
84931 |
1301 |
DA/ZtmKini |
liver weight to body weight ratio |
control condition |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
liver mass |
male |
0 days
| 8 |
32.73 |
g/kg |
0.79 |
2.24 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
84938 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
8 |
100.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
67850 |
829 |
DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
16 |
56.3 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
68210 |
829 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 5 |
12.2 |
d |
0.18 |
0.4 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
70196 |
1301 |
DA/ZtmKini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103 days-131 days |
10 |
2.8 |
% |
1.26 |
4.0 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
|
68716 |
839 |
DA/ZtmKini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103 days-131 days |
12 |
1.0 |
% |
0.78 |
2.7 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
|
|
68712 |
839 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 10 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
|
69409 |
892 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 17 |
9.0 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
34 |
days |
from 8 to 34 days |
|
|
69425 |
892 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
central nervous system integrity trait |
both |
63 days-150 days |
23 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
0 |
|
from p.i. day 7 |
|
|
68128 |
838 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
8 |
50.0 |
% |
|
|
ex vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84515 |
1178 |
DA/ZtmKini |
thymus weight to body weight ratio |
control condition |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
thymus mass |
male |
0 days
| 8 |
1.22 |
mg/g |
0.1 |
0.29 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
84937 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
female |
0 days
| 24 |
91.7 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
84466 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 10 |
14.1 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
0 |
|
from 8 to 40 days |
|
|
69410 |
892 |
DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
16 |
81.3 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
68225 |
829 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 16 |
6.8 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
days |
|
69386 |
892 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (0.09 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
0 |
15.6 |
d |
|
9.4 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
69499 |
837 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
14 |
13.4 |
d |
2.2 |
8.23 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
68209 |
829 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
12 |
50.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
|
68710 |
839 |
DA/ZtmKini |
plasma orosomucoid 1 level |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
orosomucoid 1 amount |
male |
0 days
| 8 |
419.0 |
mg/l |
82.02 |
232.0 |
radial immunodiffusion assay |
|
0.0 |
|
0 |
|
|
|
|
84929 |
1301 |
DA/ZtmKini |
spleen weight to body weight ratio |
control condition |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
spleen mass |
male |
0 days
| 8 |
0.17 |
% |
0.0 |
0.01 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
84936 |
1301 |
DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
11 |
91.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
CMO:0001402 |
|
68135 |
839 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
6 |
21.2 |
d |
0.53 |
1.3 |
in vivo visual assessment |
|
0.0 |
intradermal injection |
0 |
|
from p.i. day 7 |
|
|
68711 |
839 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 37 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 28 |
64.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
37 |
days |
from 8 to 37 days |
|
|
69378 |
892 |
DA/ZtmKini |
body weight |
control condition |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
body mass |
female |
56 days-77 days |
0 |
162.9 |
g |
|
9.5 |
body weighing method |
|
0.0 |
|
0 |
|
|
|
|
68120 |
837 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
14 |
18.5 |
d |
1.6 |
5.99 |
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
68224 |
829 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65 days-112 days |
22 |
19.6 |
d |
2.22 |
10.4 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
69493 |
837 |
DA/ZtmKini |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
total life span |
both |
63 days-150 days |
23 |
61.0 |
% |
|
|
necropsy |
|
0.0 |
intradermal injection |
0 |
|
visual observation |
ratio of deaths related to experimental autoimmune encephalomyelitis to total study population during a period of time (CMO:0003802) |
|
68129 |
838 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 6 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
84470 |
1301 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 28 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 21 |
11.5 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
28 |
days |
from 8 to 28 days |
|
|
69419 |
892 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 34 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 17 |
25.2 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
0 |
|
from 8 to 34 days |
|
|
69424 |
892 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 40 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 16 |
50.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
40 |
days |
from 8 to 40 days |
|
|
69384 |
892 |
DA/ZtmKini |
inguinal lymph node wet weight to body weight ratio |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
inguinal lymph node mass |
male |
0 days
| 8 |
0.68 |
g/kg |
0.07 |
0.21 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
84927 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (15-22 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91 days-112 days |
12 |
92.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
68122 |
837 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
10 |
80.0 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
67849 |
829 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
16 |
87.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
67852 |
829 |
DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (200 ul) |
Jagodic M, et al., J Immunol 2004 Jul 15;173(2):1366-73. |
central nervous system integrity trait |
not specified |
63 days-105 days |
8 |
87.5 |
% |
|
|
in vivo visual assessment |
whole animal |
0.0 |
injection |
40 |
days |
range 31 to 40 days |
|
|
68201 |
829 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 5 |
100.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
70192 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 18 |
16.7 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
0 |
|
from 8 to 38 days |
|
|
69391 |
892 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 31 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 18 |
14.3 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
31 |
days |
from 8 to 31 days |
days |
|
69392 |
892 |
DA/ZtmKini |
maximum body weight loss to initial body weight ratio |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
body mass |
male |
103 days-131 days |
11 |
14.4 |
% |
2.47 |
8.2 |
body weighing method |
|
0.0 |
intradermal injection |
40 |
days |
from before p.i. |
CMO:0001400 |
|
68134 |
839 |
DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
8 |
87.5 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
|
68709 |
839 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
10 |
80.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
|
|
68714 |
839 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
91 days-112 days |
22 |
82.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
0 |
|
visual observation |
|
|
69487 |
837 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug/200 ul) |
Jagodic M, et al., J Immunol 2005 Jan 15;174(2):918-24. |
central nervous system integrity trait |
both |
63 days-150 days |
20 |
60.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
0 |
|
from p.i. day 7 |
|
|
68124 |
838 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
5 |
80.0 |
% |
|
|
ex vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84529 |
1178 |
DA/ZtmKini |
thymus weight to body weight ratio |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
thymus mass |
male |
0 days
| 8 |
0.6 |
mg/g |
0.07 |
0.19 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
84932 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
female |
0 days
| 24 |
14.6 |
d |
0.63 |
3.1 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
84468 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 6 |
16.3 |
d |
0.94 |
2.3 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
84472 |
1301 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 37 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 28 |
10.7 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
37 |
days |
from 8 to 37 days |
days |
|
69381 |
892 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 18 |
94.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
38 |
days |
from 8 to 38 days |
|
|
69390 |
892 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (13-85 ug/200 ul) (for 38 days) |
Marta M, et al., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13. |
central nervous system integrity trait |
female |
0 days
| 18 |
20.9 |
d |
|
|
in vivo visual assessment |
|
0.0 |
subcutaneous injection |
38 |
days |
from 8 to 38 days |
days |
|
69393 |
892 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
12 |
14.8 |
d |
2.4 |
8.3 |
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
69491 |
837 |
DA/ZtmKini |
percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
6 |
50.0 |
% |
|
|
in vivo visual assessment |
|
0.0 |
intradermal injection |
40 |
days |
from p.i. day 7 |
CMO:0001402 |
|
68713 |
839 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (20 ug) |
Jagodic M, et al., Immunogenetics 2001 Jul;53(5):410-5. |
central nervous system integrity trait |
male |
103 days-131 days |
8 |
19.2 |
d |
1.24 |
3.5 |
in vivo visual assessment |
|
0.0 |
intradermal injection |
0 |
|
from p.i. day 7 |
|
|
68715 |
839 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 27 |
96.3 |
% |
|
|
in vivo visual assessment |
|
0.0 |
|
0 |
|
|
|
|
70188 |
1301 |