Phenominer Database Results (6 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 6 0.83 g/mg 0.08 0.19 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63188 528
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 6 -7.86 null 0.7 1.72 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62872 528
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 8 -8.55 null 0.2 0.56 wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter 63119 528
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 8 0.0 umol/l 0.0 0.0 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62796 528
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 3 45.0 % 14.84 25.71 wire myography using a Digi-Med tissue force analysis system with force transducer 0 62649 528
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 6 4.13 E-7mole 3.34 8.18 wire myography using a Digi-Med tissue force analysis system with force transducer 0 63049 528