Phenominer Database Results (16 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
SS.MNS-(D2Mit6-D2Rat303)/Ayd mean arterial blood pressure controlled sodium content diet (2 %) (between 21 and 37 days) Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28. arterial blood pressure trait male 56 days-72 days 9 168.0 mmHg 4.0 12.0 intra-aortic abdominal radiotelemetry 0 none 12325 242
SS.MNS-(D2Mit6-D2Rat303)/Ayd logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 -7.86 null 0.27 0.97 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69068 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd blood vessel contractile force measurement Kreb's solution perfusate then potassium chloride solution (40 mmol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 1.62 g 0.09 0.32 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69049 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then phenylephrine (1-100 mmol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 100.16 % 5.63 20.3 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69053 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 26.63 % 4.0 14.42 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69070 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd mean arterial blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days) Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28. arterial blood pressure trait male 66 days-80 days 8 167.0 mmHg intra-aortic abdominal radiotelemetry abdominal aorta 0.0 0 70475 1438
SS.MNS-(D2Mit6-D2Rat303)/Ayd heart left ventricle deoxyribonucleic acid content to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart left ventricle DNA amount male 98 days 5 5.0 ug/g 0.5 1.12 spectrophotometry 0.0 0 69037 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd blood vessel contractile force measurement Kreb's solution perfusate then potassium chloride solution (40 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 1.6 g 0.12 0.43 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69051 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 143.03 % 6.62 23.87 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69057 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd aorta smooth muscle cell count per unit vessel length controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. blood vessel smooth muscle cell quantity male 98 days 8 134.0 /um 21.0 59.4 ex vivo light microscopy with digital image analysis 0.0 0 /um - calculated aortic smooth muscle cell count 69032 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 19.33 % 3.67 13.23 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69066 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd heart right ventricle deoxyribonucleic acid content to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart right ventricle DNA amount male 98 days 5 1.2 ug/g 0.09 0.2 spectrophotometry 0.0 0 69042 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then phenylephrine (1-100 mmol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 -6.96 null 0.17 0.61 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer EC50 value is probably moles/liter 69055 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd mean arterial blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. arterial blood pressure trait male 68 days-98 days 9 168.0 mmHg radiotelemetry 0.0 0 69028 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 -7.2 null 0.31 1.12 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69072 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 -7.41 null 0.16 0.58 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer EC50 value is probably moles/liter 69059 1096