Phenominer Database Results (101 results)

 
 
Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Average Type Value Units SEM SD Individual Records Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 385.58 beats/min 9.77 32.41 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15336 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 452.55 beats/min 9.34 29.53 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15958 381
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 411.76 beats/min 26.24 52.48 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50667 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 405.69 beats/min 11.75 49.86 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51114 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 393.77 beats/min 10.28 43.62 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51280 481
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 37 492.45 beats/min 5.9 35.89 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13800 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 497.77 beats/min 4.55 13.64 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14063 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 502.35 beats/min Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19932 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 22 524.94 beats/min 8.14 38.2 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19954 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 448.96 beats/min 12.9 36.5 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17748 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 413.33 beats/min 15.97 45.17 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18754 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 424.61 beats/min 10.82 28.62 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18760 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 415.16 beats/min 9.54 28.61 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18194 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 409.67 beats/min 10.1 33.5 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20434 381
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 241.06 beats/min 19.12 63.42 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 50309 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 94 255.87 beats/min 4.57 44.3 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47648 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 89 209.31 beats/min 4.76 44.94 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45214 461
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (between 50 and 52 days) then controlled sodium content diet (4 %) (for 21 days) Cowley AW Jr, et al., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7. heart pumping trait male 71.0 days-73.0 days 8 serial mean 405.0 beats/min 2.0 5.66 intra-aortic thoracic radiotelemetry via carotid cannulation 86400.0 98639 2118
SS/JrHsdMcwi heart rate isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart pumping trait male 49.0 days-56.0 days 5 384.0 beats/min 6.0 13.42 transthoracic echocardiography 0.0 105832 3023
SS/JrHsdMcwi heart rate angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart pumping trait male 63.0 days-70.0 days 5 394.0 beats/min 6.0 13.42 transthoracic echocardiography 0.0 105834 3023
SS/JrHsdMcwi heart rate monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart pumping trait male 56.0 days 8 340.0 beats/min 7.65 21.64 vascular fluid filled catheter 0.0 106800 3032
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 427.49 beats/min 15.86 38.84 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15191 381
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 418.52 beats/min 9.02 27.06 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15345 381
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 93.0 days 12 serial mean 427.0 beats/min 6.0 20.78 vascular indwelling catheter method left femoral artery 0 65469 151
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 451.75 beats/min 12.93 44.79 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50529 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 386.98 beats/min 5.77 22.33 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50878 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 384.83 beats/min 13.09 29.27 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51482 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 400.82 beats/min 9.27 39.31 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51577 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 10 401.83 beats/min 4.13 13.07 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51583 481
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 411.25 beats/min 8.66 27.37 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14728 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 451.63 beats/min 7.56 25.06 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20952 381
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (for 21 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 89.0 days-92.0 days 20 serial mean 437.0 beats/min 6.0 26.83 vascular indwelling catheter method left femoral artery 13310 151
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 430.66 beats/min 12.88 38.63 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18110 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 61 412.19 beats/min 6.25 48.79 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17529 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 452.61 beats/min 5.11 16.16 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20443 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 565.64 beats/min 9.72 27.48 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20526 381
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 278.97 beats/min 33.96 89.86 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 50316 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 317.09 beats/min 22.83 64.57 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46517 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 17 285.02 beats/min 10.4 42.89 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47653 461
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 411.41 beats/min 9.43 31.29 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16351 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 447.76 beats/min 12.54 37.63 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16360 381
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (for 13 days) PhysGen Knockout data heart pumping trait male 70.0 days-77.0 days 6 350.0 beats/min 5.25 12.85 Download Values radiotelemetry carotid artery - 43745 441
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 306.28 beats/min 21.0 63.01 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 47683 461
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 19 251.86 beats/min 7.82 34.1 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48269 461
SS/JrHsdMcwi heart rate control condition (0.4 %) (between 50 and 52 days) Cowley AW Jr, et al., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7. heart pumping trait male 50.0 days-52.0 days 8 serial mean 446.0 beats/min 5.0 14.14 intra-aortic thoracic radiotelemetry via carotid cannulation 86400.0 98641 2118
SS/JrHsdMcwi heart rate angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart pumping trait male 77.0 days-84.0 days 5 358.0 beats/min 17.0 38.01 transthoracic echocardiography 0.0 105836 3023
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 50 419.34 beats/min 5.77 40.82 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15953 381
SS/JrHsdMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 416.02 beats/min 6.59 19.78 Download Values vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52667 482
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 17 406.36 beats/min 7.25 29.89 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50523 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 432.92 beats/min 10.44 36.17 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51119 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 16 386.28 beats/min 7.72 30.88 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50471 481
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 419.73 beats/min 8.86 28.02 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20971 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 500.7 beats/min 32.3 55.95 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19938 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 48 409.84 beats/min 3.74 25.89 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17743 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 430.16 beats/min 6.98 23.14 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18101 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 574.36 beats/min 4.48 11.85 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20535 381
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 176.76 beats/min 23.92 41.43 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 49822 461
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 12 307.19 beats/min 12.38 42.87 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 47676 461
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (for 12 days) PhysGen Knockout data heart pumping trait male 70.0 days-77.0 days 7 362.0 beats/min 6.26 16.56 Download Values radiotelemetry carotid artery - 44610 441
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 4 303.31 beats/min 13.52 27.03 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45870 461
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 2 282.35 beats/min 17.65 24.96 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 48153 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 1 187.41 beats/min Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45077 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 226.32 beats/min 12.63 35.73 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45247 461
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 94.0 days 10 serial mean 411.7 beats/min 10.6 33.52 vascular indwelling catheter method left femoral artery 10800.0 69526 151
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 89.0 days-91.0 days 15 serial mean 442.0 beats/min 6.5 25.17 vascular indwelling catheter method left femoral artery 0.0 69450 151
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. heart pumping trait male 60.0 days-67.0 days 12 serial mean 388.0 beats/min 6.0 20.78 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry intra-carotid radiotelemetry 98609 2098
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (between 23 and 32 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. heart pumping trait male 44.0 days-53.0 days 14 serial mean 414.0 beats/min 5.0 18.71 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant 98514 2079
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 450.69 beats/min 12.38 24.77 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15197 381
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 401.38 beats/min 19.18 38.37 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15594 381
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 383.68 beats/min 7.38 31.32 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51245 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 393.13 beats/min 12.55 28.06 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51380 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 387.81 beats/min 8.14 31.52 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50323 481
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 51 370.19 beats/min 5.38 38.45 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14723 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 517.71 beats/min 27.96 48.43 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13832 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 531.15 beats/min 5.18 13.7 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14072 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 436.5 beats/min 7.29 19.29 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20977 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 473.71 beats/min 17.29 29.95 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17668 381
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 19 234.02 beats/min 12.74 55.51 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49017 461
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data heart pumping trait male 70.0 days-77.0 days 6 344.67 beats/min 2.51 6.15 Download Values radiotelemetry carotid artery - 44055 441
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 89 260.18 beats/min 3.7 34.91 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48264 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 265.53 beats/min 34.79 130.15 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45219 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 284.37 beats/min 31.65 89.53 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45253 461
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 92.0 days 21 serial mean 425.4 beats/min 10.5 48.12 vascular indwelling catheter method left femoral artery 10800.0 69514 151
SS/JrHsdMcwi heart rate controlled sodium chloride content diet (0.4 %) (between 23 and 32 days) then controlled sodium chloride content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. heart pumping trait male 58.0 days-67.0 days 14 serial mean 387.0 beats/min 6.0 22.45 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant 98521 2079
SS/JrHsdMcwi heart rate isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart pumping trait male 147.0 days 10 383.0 beats/min 6.0 18.97 transthoracic echocardiography 0.0 105802 3023
SS/JrHsdMcwi heart rate vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart pumping trait male 56.0 days 6 358.0 beats/min 7.95 19.47 vascular fluid filled catheter 0.0 106798 3032
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 381.66 beats/min 15.84 41.9 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15588 381
SS/JrHsdMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 59 400.39 beats/min 4.05 31.09 Download Values vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52661 482
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 10 407.56 beats/min 6.03 19.06 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51250 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 3 356.33 beats/min 4.7 8.14 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50445 481
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 522.7 beats/min 7.28 21.83 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13805 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 446.53 beats/min 77.6 155.19 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13826 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 62 413.02 beats/min 4.88 38.45 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20947 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 517.01 beats/min 6.36 16.81 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19963 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 396.58 beats/min 15.33 30.67 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17662 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 452.93 beats/min 8.97 28.36 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17534 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 487.67 beats/min 8.92 23.59 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18203 381
SS/JrHsdMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 83 236.93 beats/min 8.57 78.04 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49012 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 294.78 beats/min 8.27 27.42 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46511 461
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (for 11 days) PhysGen Knockout data heart pumping trait male 70.0 days-77.0 days 7 360.86 beats/min 6.22 16.45 Download Values radiotelemetry carotid artery - 44671 441
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 93.0 days 11 serial mean 446.8 beats/min 9.7 32.17 vascular indwelling catheter method left femoral artery 10800.0 69520 151