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Study IDStudyExperiment NameExperiment NotesStrain Ont IDStrainSexAge# of AnimalsSample NotesClinical Measurement Ont IDPhenotypeFormulaClinical Measurement NotesAverage TypeValueUnitsSEMSDMethod Ont IDMethodMethod SiteMethod DurationMethod NotesPost Insult TypePost Insult Time ValuePost Insult Time UnitConditionsRecord IDCondition 1Condition 2aCondition 2bCondition 3Condition 4
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days11CMO:0000709methylene blue metabolism-surface area product without auto-oxidation19.7277ml/min/kg1.38424.5908MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)57856air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days12CMO:0000709methylene blue metabolism-surface area product without auto-oxidation25.3167ml/min/kg2.58418.9515MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)57861air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days11CMO:0000710methylene blue metabolism-surface area product after auto-oxidation13.4283ml/min/kg0.71662.3767MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours)57654air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)sample resting period (for 0.1 hours)
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days12CMO:0000710methylene blue metabolism-surface area product after auto-oxidation14.9432ml/min/kg1.3874.8048MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours)57659air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)sample resting period (for 0.1 hours)
461PhysGen Cardiac dataheart massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days10CMO:0000069heart wet weight0.622g0.03860.122MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)45460air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataheart massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000069heart wet weight0.749g0.03910.1238MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)45465air oxygen content (12 %) (for 14 days)
381PhysGen Respiratory datarespiratory function traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000531percent change in respiration rate117.1248%6.905823.9222MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)54382air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000531percent change in respiration rate124.5128%10.016133.2197MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)54387air oxygen content (12 %) (between 0 and 0.1 hours)
461PhysGen Cardiac dataarterial blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days8CMO:0000198arterial blood flow rate5.3275ml/min/g0.36441.0308MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)44773air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataarterial blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000198arterial blood flow rate4.298ml/min/g0.15870.5019MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)44778air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days8CMO:0000002heart rate228.1675beats/min8.633324.4186MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45203air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000002heart rate201.828beats/min12.415339.2607MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45208air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000018left ventricular developed pressure22.7289mmHg5.510116.5302MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45325air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000018left ventricular developed pressure30.006mmHg4.658714.7319MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45330air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000007left ventricular systolic blood pressure78.9156mmHg4.845414.5361MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49943air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000007left ventricular systolic blood pressure89.041mmHg6.571720.7814MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49948air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart muscle contractility traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000665heart contraction pressure28mmHg1.77175.3151MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)50052air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart muscle contractility traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000665heart contraction pressure34.5mmHg3.13859.9247MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)50057air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000664time to peak heart contraction1046.2222s43.5663130.6989MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)50282air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000664time to peak heart contraction1134.3s50.2293158.8389MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)50287air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac databody massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days10CMO:0000012body weight117.1g6.821.5MMO:0000017whole body digital scaleair oxygen content (12 %) (for 14 days)49536air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac databody massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000012body weight122.4g5.617.6MMO:0000017whole body digital scaleair oxygen content (12 %) (for 14 days)49542air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataheart left ventricle integrity traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days8CMO:0000695heart left ventricle infarction weight to total heart left ventricle weight ratio20.92%5.345115.1182MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours)49753air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 3 hours)
461PhysGen Cardiac dataheart left ventricle integrity traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days9CMO:0000695heart left ventricle infarction weight to total heart left ventricle weight ratio11.0878%2.63957.9186MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours)49758air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 3 hours)
461PhysGen Cardiac dataheart muscle contractility traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days6CMO:0000663time to onset of heart contraction844.8333s29.576472.447MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)49354air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart muscle contractility traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000663time to onset of heart contraction932.6s36.1771114.402MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)49359air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000288percent change in ventilation%change=VE during 2-3 min hypoxia/control during standard conditions131.3803%6.780522.4884MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)13742air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000532percent change in tidal volume113.7317%4.336115.0205MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)53941air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000532percent change in tidal volume109.665%6.84822.7122MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)53946air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000532percent change in tidal volume110.0498%5.589219.3615MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)54042air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000532percent change in tidal volume104.2804%7.070123.4489MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)54047air oxygen content (12 %) (between 0.1 and 0.1 hours)
401PhysGen Biochemistry datablood alkaline phosphatase amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000577serum alkaline phosphatase activity level251.2857U/l14.097837.2993MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36435air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood alkaline phosphatase amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000577serum alkaline phosphatase activity level199.1667U/l29.688872.7225MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36440air oxygen content (12 %) (for 14 days)
526PhysGen Lung dataheart right ventricle massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days15CMO:0000108heart right ventricle weight to left ventricle weight ratio0.4330.02630.102MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)58789air oxygen content (12 %) (for 14 days)
526PhysGen Lung dataheart right ventricle massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days14CMO:0000108heart right ventricle weight to left ventricle weight ratio0.40670.0250.0936MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)58794air oxygen content (12 %) (for 14 days)
381PhysGen Respiratory datablood acidity-alkalinity balance traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days4CMO:0000300absolute change in blood pH0.04190.01180.0236MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)19790air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood acidity-alkalinity balance traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days2CMO:0000300absolute change in blood pH0.0030.00.0MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)19796air oxygen content (12 %) (for 0.1 hours)
526PhysGen Lung databody massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days15CMO:0000012body weight184g12.447.9MMO:0000017whole body digital scaleair oxygen content (12 %) (for 14 days)59118air oxygen content (12 %) (for 14 days)
526PhysGen Lung databody massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days14CMO:0000012body weight131g7.528.0MMO:0000017whole body digital scaleair oxygen content (12 %) (for 14 days)59123air oxygen content (12 %) (for 14 days)
526PhysGen Lung dataerythrocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000037hematocrit52.2571%0.73671.9492MMO:0000215microhematocrit tube assay with visual assessmentair oxygen content (12 %) (for 14 days)59313air oxygen content (12 %) (for 14 days)
526PhysGen Lung dataerythrocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000037hematocrit48.0714%1.53514.0615MMO:0000215microhematocrit tube assay with visual assessmentair oxygen content (12 %) (for 14 days)59318air oxygen content (12 %) (for 14 days)
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days14CMO:0000703calculated pulmonary vascular resistance normalized to body weight0.1288mmHg x min x kg x ml-10.00780.029MMO:0000203fluid-filled catheter with pressure transducer in isolated perfused lungair oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)59603air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days12CMO:0000703calculated pulmonary vascular resistance normalized to body weight0.1208mmHg x min x kg x ml-10.00580.0202MMO:0000203fluid-filled catheter with pressure transducer in isolated perfused lungair oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)59608air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
526PhysGen Lung datalung massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days15CMO:0000102lung dry weight to body weight ratio1.375g/kg0.03780.1466MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)59713air oxygen content (12 %) (for 14 days)
526PhysGen Lung datalung massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days12CMO:0000102lung dry weight to body weight ratio1.4499g/kg0.02430.0843MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)59718air oxygen content (12 %) (for 14 days)
526PhysGen Lung datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days11CMO:0000713dose of methacholine at which pulmonary conductance is half its pretreatment value1.197mg/kg0.21110.7002MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)58962air oxygen content (12 %) (for 14 days)methacholine (0-11.06 mg/kg) drug dose time series (for 0.2 hours)
526PhysGen Lung datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000713dose of methacholine at which pulmonary conductance is half its pretreatment value1.5063mg/kg0.37130.9095MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)58967air oxygen content (12 %) (for 14 days)methacholine (0-11.06 mg/kg) drug dose time series (for 0.2 hours)
526PhysGen Lung datablood vessel distensibility traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days14CMO:0000714fractional change in blood vessel diameter per unit change in intravascular pressure0.035mmHg-10.00370.0137MMO:0000203fluid-filled catheter with pressure transducer in isolated perfused lungair oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)58545air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
526PhysGen Lung datablood vessel distensibility traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days12CMO:0000714fractional change in blood vessel diameter per unit change in intravascular pressure0.0252mmHg-10.00290.0102MMO:0000203fluid-filled catheter with pressure transducer in isolated perfused lungair oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)58550air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
401PhysGen Biochemistry datablood hemoglobin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000290mean corpuscular hemoglobin18.9857pg0.26130.6914MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)42601air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000290mean corpuscular hemoglobin18.9571pg0.12120.3207MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)42606air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood chloride amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000489serum chloride level109.1429mmol/l0.70471.8645MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39173air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood chloride amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000489serum chloride level109.5mmol/l0.9222.2583MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39178air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood urea nitrogen amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000587serum urea nitrogen level23.4286mg/dl1.25093.3094MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)40884air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood urea nitrogen amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000587serum urea nitrogen level30.6667mg/dl2.47216.0553MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)40889air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000025red blood cell count8.9386x 10E6 cells/ul0.10430.2759MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39293air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000025red blood cell count8.1157x 10E6 cells/ul0.27560.7292MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39298air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataleukocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000365total white blood cell count7.2286x 1000 cells/ul0.41391.095MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)40982air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataleukocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000365total white blood cell count5.5571x 1000 cells/ul0.68731.8183MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)40987air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood aspartate transaminase amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000581serum aspartate aminotransferase activity level88.2857U/l4.246611.2356MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42826air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood aspartate transaminase amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000581serum aspartate aminotransferase activity level67.8333U/l5.582213.6736MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42831air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood sodium amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000500serum sodium level144mmol/l0.57741.5275MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39444air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood sodium amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000500serum sodium level144.5mmol/l1.08782.6646MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39449air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood phosphate amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000542serum phosphate level9.5571mg/dl0.37851.0014MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37650air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood phosphate amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000542serum phosphate level11.2667mg/dl0.70171.7189MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37655air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataneutrophil quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000030blood neutrophil count0.7814x 1000 cells/ul0.07350.1944MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)43280air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataneutrophil quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000030blood neutrophil count0.7586x 1000 cells/ul0.13710.3628MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)43285air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood creatinine amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000537plasma creatinine level0.3143mg/dl0.01430.0378MMO:0000354automated plasma creatinine analysisair oxygen content (12 %) (for 14 days)39632air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood creatinine amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000537plasma creatinine level0.4333mg/dl0.04940.1211MMO:0000354automated plasma creatinine analysisair oxygen content (12 %) (for 14 days)39637air oxygen content (12 %) (for 14 days)
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days12CMO:0000708FAPGG metabolism-surface area product47.5633ml/min/kg6.072621.0362MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours)58055air oxygen content (12 %) (for 14 days)FAPGG (0.6 mmol/l) (between 0 and 0 hours)
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days11CMO:0000708FAPGG metabolism-surface area product60.8272ml/min/kg8.025126.6163MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours)58060air oxygen content (12 %) (for 14 days)FAPGG (0.6 mmol/l) (between 0 and 0 hours)
401PhysGen Biochemistry datamonocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000032blood monocyte count0.32x 1000 cells/ul0.03720.0985MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39730air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datamonocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000032blood monocyte count0.2029x 1000 cells/ul0.05270.1394MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39735air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000026blood hemoglobin level16.9571g/dl0.26530.702MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38024air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000026blood hemoglobin level15.3857g/dl0.48471.2825MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38029air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000291mean corpuscular hemoglobin concentration32.4714g/dl0.25330.6701MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39833air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000291mean corpuscular hemoglobin concentration31.9571g/dl0.21480.5682MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39838air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datalymphocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000031blood lymphocyte count6.12x 1000 cells/ul0.43591.1532MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)41559air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datalymphocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000031blood lymphocyte count4.58x 1000 cells/ul0.67821.7943MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)41564air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood potassium amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000495serum potassium level5.4714mmol/l0.23880.6317MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38122air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood potassium amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000495serum potassium level4.3167mmol/l0.27250.6676MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38127air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataeosinophil quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000033blood eosinophil count0.0086x 1000 cells/ul0.00860.0227MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)41703air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataeosinophil quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000033blood eosinophil count0.0143x 1000 cells/ul0.00920.0244MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)41708air oxygen content (12 %) (for 14 days)
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days10CMO:0000711methylene blue to FAPGG metabolism-surface area product ratio0.47020.04070.1288MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58169air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
526PhysGen Lung datapulmonary blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days11CMO:0000711methylene blue to FAPGG metabolism-surface area product ratio0.43330.03480.1154MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58174air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
401PhysGen Biochemistry dataion homeostasis traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000066plasma anion gap18.7143mmol/l1.08482.8702MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38317air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataion homeostasis traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000066plasma anion gap19mmol/l1.84394.5166MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38322air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood bilirubin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000376serum total bilirubin level0.1mg/dl0.00.0MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)41924air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood bilirubin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000376serum total bilirubin level0.15mg/dl0.02240.0548MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)41929air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood calcium amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000503serum calcium level9.1mg/dl0.09510.2517MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36680air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood calcium amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000503serum calcium level9.4833mg/dl0.26880.6585MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36685air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood glucose amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000543serum glucose level138.2857mg/dl1.87364.957MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38586air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood glucose amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000543serum glucose level154.3333mg/dl18.869146.2198MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38591air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood bicarbonate amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000488serum bicarbonate level21.5714mmol/l1.17223.1015MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42118air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood bicarbonate amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000488serum bicarbonate level20.1667mmol/l1.10812.7142MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42123air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood globulin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0002399serum globulin levelreplaced obsolete serum globulin level term, 1/19/20161.7g/dl0.03090.0816MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)40606air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood globulin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0002399serum globulin levelreplaced obsolete serum globulin level term, 1/19/20161.5g/dl0.03650.0894MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)40611air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood albumin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000550serum albumin level3.8571g/dl0.1110.2936MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42289air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood albumin amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000550serum albumin level3.7667g/dl0.12820.3141MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42294air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood total protein amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000661serum total protein level5.5571g/dl0.1270.3359MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37018air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood total protein amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000661serum total protein level5.2667g/dl0.11160.2733MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37023air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte size traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000038mean corpuscular volume58.4714fl0.53751.4221MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38801air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte size traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000038mean corpuscular volume59.3286fl0.4771.2619MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38806air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood cholesterol amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000363serum total cholesterol level76.7143mg/dl3.68219.7419MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37153air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood cholesterol amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000363serum total cholesterol level84.6667mg/dl3.35338.2138MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37158air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood alanine transaminase amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000575serum alanine aminotransferase activity level58.7143U/l3.840410.1606MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)40770air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood alanine transaminase amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days6CMO:0000575serum alanine aminotransferase activity level50.6667U/l7.596818.6082MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)40775air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale91 days to 77 days7CMO:0000037hematocrit52.2571%0.73671.9492MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39047air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte quantityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale91 days to 77 days7CMO:0000037hematocrit48.0714%1.53514.0615MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39052air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataarterial blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days8CMO:0000198arterial blood flow rate10.4075ml/min/g1.04552.9571MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)46708air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataarterial blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000198arterial blood flow rate9.119ml/min/g0.68092.1533MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)46713air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000006left ventricular diastolic blood pressure4.8611mmHg0.40941.2283MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47252air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000006left ventricular diastolic blood pressure6.308mmHg0.25420.8037MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47257air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days8CMO:0000742percent change in heart ratepost-ischemic value/pre-ischemic value x 100%88.2522%1.92425.4426MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)48350air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days9CMO:0000742percent change in heart ratepost-ischemic value/pre-ischemic value x 100%78.7347%3.860111.5804MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)48355air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000751percent change in left ventricular developed pressurepost-ischemic value/pre-ischemic value x 100%26.2141%6.914920.7448MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)48582air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days9CMO:0000751percent change in left ventricular developed pressurepost-ischemic value/pre-ischemic value x 100%32.478%4.74814.2441MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)48587air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000018left ventricular developed pressure87.2244mmHg4.063512.1906MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48679air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000018left ventricular developed pressure81.85mmHg6.081419.2312MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48684air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000754percent change in left ventricular systolic blood pressurepost-ischemic value/pre-ischemic value x 100%86.8798%6.385619.1568MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)48811air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days9CMO:0000754percent change in left ventricular systolic blood pressurepost-ischemic value/pre-ischemic value x 100%96.2787%4.533613.6008MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)48816air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
381PhysGen Respiratory datarespiratory function traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000289respiration rate120.9922breaths/min8.326728.8447MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)18322air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000289respiration rate111.214breaths/min5.037616.7078MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)18327air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000531percent change in respiration rate107.1162%5.254718.2028MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)53809air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000531percent change in respiration rate123.7697%9.64331.9823MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)53814air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory databody temperature traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000015body temperature37.3583degrees C0.21790.7549MMO:0000034digital rectal thermometryair oxygen content (12 %) (for 0.1 hours)16629air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory databody temperature traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000015body temperature37.2727degrees C0.14590.4839MMO:0000034digital rectal thermometryair oxygen content (12 %) (for 0.1 hours)16634air oxygen content (12 %) (for 0.1 hours)
461PhysGen Cardiac dataheart massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days10CMO:0000074heart weight to body weight ratio5.388g/kg0.3561.124MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)45634air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataheart massMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000074heart weight to body weight ratio6.187g/kg0.331.042MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)45640air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataheart lactate dehydrogenase activityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days8CMO:0000775heart effluent lactate dehydrogenase activity level normalized to heart weight0.5272IU/g0.08290.2345MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47462air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart lactate dehydrogenase activityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000775heart effluent lactate dehydrogenase activity level normalized to heart weight0.3942IU/g0.03430.1084MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47467air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000007left ventricular systolic blood pressure92.0856mmHg3.831711.4951MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)45784air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000007left ventricular systolic blood pressure88.158mmHg5.924118.7337MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)45789air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000006left ventricular diastolic blood pressure56.1867mmHg4.65713.9709MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46472air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000006left ventricular diastolic blood pressure59.035mmHg4.295113.5822MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46477air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days9CMO:0000002heart rate257.1389beats/min8.390125.1703MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47637air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days9CMO:0000002heart rate268.88beats/min13.597240.7915MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47642air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataarterial blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days8CMO:0000749percent change in arterial blood flow ratepost-ischemic value/pre-ischemic value x 100%55.2181%6.661118.8403MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47132air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataarterial blood flow traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000749percent change in arterial blood flow ratepost-ischemic value/pre-ischemic value x 100%48.9898%3.500511.0696MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47137air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart lactate dehydrogenase activityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale63 days to 49 days8CMO:0000775heart effluent lactate dehydrogenase activity level normalized to heart weight18.6205IU/g3.30949.3604MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours)45978air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 1.5 hours)
461PhysGen Cardiac dataheart lactate dehydrogenase activityMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale63 days to 49 days10CMO:0000775heart effluent lactate dehydrogenase activity level normalized to heart weight15.7838IU/g1.0173.2159MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours)45983air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 1.5 hours)
381PhysGen Respiratory datablood oxygen amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days4CMO:0000299absolute change in partial pressure of blood oxygen-41.7mmHg8.053716.1073MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)19469air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood oxygen amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days2CMO:0000299absolute change in partial pressure of blood oxygen-58.5mmHg10.715.1321MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)19475air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood acidity-alkalinity balance traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days6CMO:0000379blood pH7.49560.01080.0265MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)17054air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood acidity-alkalinity balance traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days2CMO:0000379blood pH7.51550.02250.0318MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)17060air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000222tidal volume0.3613ml0.02660.0921MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)13980air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000222tidal volume0.2935ml0.01640.0543MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)13985air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000132minute ventilation32.3565ml/min2.01336.6773MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)18724air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days5CMO:0000009mean arterial blood pressure127.738mmHg7.402716.553MMO:0000013vascular fluid filled catheterair oxygen content (12 %) (for 0.1 hours)14336air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days5CMO:0000009mean arterial blood pressure140.788mmHg7.375216.4915MMO:0000013vascular fluid filled catheterair oxygen content (12 %) (for 0.1 hours)14342air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000289respiration rate110.9289breaths/min8.357528.9511MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)14851air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000289respiration rate111.2997breaths/min5.550818.4099MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)14856air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000222tidal volume0.3498ml0.030.1039MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)15290air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000222tidal volume0.2786ml0.01750.0581MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)15295air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000288percent change in ventilation%change=VE during 2-3 min hypoxia/control during standard conditions131.7056%6.408822.2008MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)13737air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datablood carbon dioxide amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days4CMO:0000298absolute change in partial pressure of blood carbon dioxide-5mmHg1.04642.0928MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)19638air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000132minute ventilation37.9342ml/min3.39911.7746MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)20265air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000132minute ventilation30.8552ml/min2.28637.5827MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)20270air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datablood carbon dioxide amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days2CMO:0000298absolute change in partial pressure of blood carbon dioxide-6.65mmHg1.051.4849MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)19644air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood gas amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days6CMO:0000283partial pressure of blood carbon dioxide (Pco2)29.25mmHg1.05252.5782MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)17246air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood gas amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days2CMO:0000283partial pressure of blood carbon dioxide (Pco2)26.75mmHg4.155.869MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)17252air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days5CMO:0000002heart rate400.208beats/min26.781159.8844MMO:0000013vascular fluid filled catheterair oxygen content (12 %) (for 0.1 hours)17509air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days5CMO:0000002heart rate406.64beats/min9.801521.9169MMO:0000013vascular fluid filled catheterair oxygen content (12 %) (for 0.1 hours)17515air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory databody temperature traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000699absolute change in body temperature0.1083degrees C0.24760.8575MMO:0000034digital rectal thermometryair oxygen content (12 %) (for 0.1 hours)20366air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory databody temperature traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days11CMO:0000699absolute change in body temperature-0.1545degrees C0.21630.7174MMO:0000034digital rectal thermometryair oxygen content (12 %) (for 0.1 hours)20371air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days12CMO:0000132minute ventilation43.2442ml/min4.313714.943MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)18719air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datablood oxygen amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwimale99 days to 82 days6CMO:0000381partial pressure of blood oxygen61.7167mmHg1.84224.5124MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)20481air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood oxygen amountMoms and pups used in studies were fed TekladRS:0000803SS-Chr 3BN/Mcwifemale99 days to 82 days2CMO:0000381partial pressure of blood oxygen61.05mmHg2.854.0305MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)20487air oxygen content (12 %) (for 0.1 hours)