SS-Chr 16BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87 days-120 days |
6 |
129.19 |
mmHg |
3.08 |
7.55 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
51822 |
481 |
SS-Chr 16BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87 days-120 days |
7 |
108.35 |
mmHg |
1.6 |
4.22 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51328 |
481 |
SS-Chr 16BN/Mcwi |
heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
female |
87 days-120 days |
5 |
423.79 |
beats/min |
7.38 |
16.5 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51382 |
481 |
SS-Chr 16BN/Mcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
male |
87 days-120 days |
10 |
21.46 |
beats/min |
11.94 |
37.77 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
51091 |
481 |
SS-Chr 16BN/Mcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
male |
87 days-120 days |
7 |
4.05 |
beats/min |
12.42 |
32.85 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50909 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
3.3 |
ng/ml/h |
0.43 |
0.97 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50568 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
6 |
2.26 |
ng/ml/h |
0.6 |
1.47 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50570 |
481 |
SS-Chr 16BN/Mcwi |
heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
male |
87 days-120 days |
10 |
386.76 |
beats/min |
11.54 |
36.49 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
51248 |
481 |
SS-Chr 16BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87 days-120 days |
10 |
123.09 |
mmHg |
2.44 |
7.73 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
51824 |
481 |
SS-Chr 16BN/Mcwi |
urine sodium excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
urine sodium amount |
female |
87 days-120 days |
6 |
1.4 |
mEq/d |
0.14 |
0.34 |
flame atomic emission spectrometry |
|
0 |
Moms and pups used in studies were fed Dyets |
51267 |
481 |
SS-Chr 16BN/Mcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
female |
87 days-120 days |
6 |
-4.01 |
beats/min |
12.94 |
31.69 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
51089 |
481 |
SS-Chr 16BN/Mcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87 days-120 days |
5 |
-5.64 |
mmHg |
2.48 |
5.55 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50764 |
481 |
SS-Chr 16BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.35 |
mg/dl |
0.01 |
0.03 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51536 |
481 |
SS-Chr 16BN/Mcwi |
heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
male |
87 days-120 days |
7 |
368.95 |
beats/min |
11.17 |
29.55 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51384 |
481 |
SS-Chr 16BN/Mcwi |
urine sodium excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
urine sodium amount |
female |
87 days-120 days |
6 |
1.16 |
mEq/d |
0.02 |
0.04 |
flame atomic emission spectrometry |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51047 |
481 |
SS-Chr 16BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.37 |
mg/dl |
0.02 |
0.05 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51174 |
481 |
SS-Chr 16BN/Mcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87 days-120 days |
6 |
-4.07 |
mmHg |
2.8 |
6.86 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
50628 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
5.67 |
ng/ml/h |
1.28 |
2.87 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50390 |
481 |
SS-Chr 16BN/Mcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
female |
87 days-120 days |
5 |
1.27 |
ml/min |
0.09 |
0.19 |
urine creatinine analysis |
|
0 |
Moms and pups used in studies were fed Dyets |
51543 |
481 |
SS-Chr 16BN/Mcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
male |
87 days-120 days |
7 |
1.93 |
ml/min |
0.1 |
0.27 |
urine creatinine analysis |
|
0 |
Moms and pups used in studies were fed Dyets |
51546 |
481 |
SS-Chr 16BN/Mcwi |
urine sodium excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
urine sodium amount |
male |
87 days-120 days |
10 |
1.62 |
mEq/d |
0.15 |
0.47 |
flame atomic emission spectrometry |
|
0 |
Moms and pups used in studies were fed Dyets |
51269 |
481 |
SS-Chr 16BN/Mcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87 days-120 days |
10 |
-13.4 |
mmHg |
2.93 |
9.26 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
50630 |
481 |
SS-Chr 16BN/Mcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
female |
87 days-120 days |
4 |
1.14 |
ml/min |
0.06 |
0.13 |
urine creatinine analysis |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51450 |
481 |
SS-Chr 16BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87 days-120 days |
5 |
108.6 |
mmHg |
0.71 |
1.58 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51326 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
3.34 |
ng/ml/h |
0.14 |
0.39 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50393 |
481 |
SS-Chr 16BN/Mcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
male |
87 days-120 days |
5 |
1.54 |
ml/min |
0.24 |
0.55 |
urine creatinine analysis |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51452 |
481 |
SS-Chr 16BN/Mcwi |
urine sodium excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
urine sodium amount |
male |
87 days-120 days |
8 |
1.07 |
mEq/d |
0.18 |
0.5 |
flame atomic emission spectrometry |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51049 |
481 |
SS-Chr 16BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
7 |
0.35 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51177 |
481 |
SS-Chr 16BN/Mcwi |
heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
female |
87 days-120 days |
6 |
390.2 |
beats/min |
8.98 |
21.99 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
51246 |
481 |
SS-Chr 16BN/Mcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87 days-120 days |
7 |
-11.26 |
mmHg |
2.11 |
5.58 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50766 |
481 |
SS-Chr 16BN/Mcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
female |
87 days-120 days |
5 |
21.19 |
beats/min |
4.88 |
10.9 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50907 |
481 |
SS-Chr 16BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
6 |
0.3 |
mg/dl |
0.06 |
0.15 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51538 |
481 |