Phenominer Database Results (85 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then apamin (100 ug/kg) and charybdotoxin (100 ug/kg) and 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -10.0 mmHg 1.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67273 731
SR/Hsd mean arterial blood pressure controlled sodium content diet (4 %) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 110.0 mmHg 4.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67234 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then ruthenium red (3 mg/kg) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -6.0 mmHg 2.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67240 731
SR/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 139.3 mmol/l 1.6 3.92 flame atomic emission spectrometry 0.0 0 102235 2682
SR/Hsd plasma osmolality controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 301.6 umol/g 3.8 9.31 osmometry 0.0 0 p osmolality mosm/kg 102239 2682
SR/Hsd creatinine clearance controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. glomerular filtration trait male 91 days 8 6.1 ml/min 0.28 0.8 urine creatinine analysis 0.0 0 102289 2683
SR/Hsd body weight gain artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. body mass male 52 days-61 days 0 65.0 g 4.0 body weighing method 0.0 0 change from surgery weight (2wks) 103214 2801
SR/Hsd water intake drink rate to body weight ratio arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. drinking behavior trait male 89 days-95 days 10 0.76 ml/d/kg 0.09 0.28 drink intake measuring method 0.0 arterial catheter implantation 1 days Water consumed (g) postsurgery per 100 g BW 107160 3077
SR/Hsd range of heart rate variation during variation of mean arterial blood pressure artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. heart pumping trait male 52 days-61 days 6 211.0 beats/min 18.0 44.09 vascular indwelling catheter method 0.0 0 change in heart rate to change in mean arterial blood pressure ratio (range) (CMO:0003896) 138430 2801
SR/Hsd mean arterial blood pressure artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. arterial blood pressure trait male 52 days-61 days 0 107.0 mmHg 2.0 vascular indwelling catheter method 0.0 0 138366 2801
SR/Hsd heart rate aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. heart pumping trait male 49 days-57 days 0 451.0 beats/min 12.0 vascular indwelling catheter method 0.0 0 138375 2801
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then ruthenium red (3 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 7.0 mmHg 1.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67269 731
SR/Hsd plasma total cholesterol level controlled sodium content diet (0.3 %) then fasting (for 16 hours) Herrera VL, et al., Circ Res 2004 Mar 5; 94(4):446-52 blood cholesterol amount male 180 days 14 66.41 mg/dl 4.63 17.34 plasma total cholesterol measurement test 0 11889 204
SR/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) then surgical denervation (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 139.6 mmol/l 1.4 3.43 flame atomic emission spectrometry 0.0 0 102250 2682
SR/Hsd plasma osmolality controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 298.6 umol/g 3.8 9.31 osmometry 0.0 0 p osmolality mosm/kg 102257 2682
SR/Hsd plasma osmolality controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 298.7 umol/g 3.2 7.84 osmometry 0.0 0 p osmolality mosm/kg 102259 2682
SR/Hsd plasma osmolality controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) then surgical denervation (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 300.9 umol/g 3.7 9.06 osmometry 0.0 0 p osmolality mosm/kg 102260 2682
SR/Hsd mean arterial blood pressure controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. arterial blood pressure trait male 91 days 8 114.0 mmHg 2.12 6.0 tail cuff plethysmography 0.0 0 102269 2683
SR/Hsd urine sodium level standard diet Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine sodium amount male 49 days 8 0.3 mmol/l 0.04 0.1 urine sodium analysis 0.0 0 102281 2683
SR/Hsd plasma potassium level aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. blood potassium amount male 49 days-56 days 0 4.8 mmol/l 0.3 potassium ion-selective electrode method 0.0 0 - 103223 2801
SR/Hsd hematocrit artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. erythrocyte quantity male 49 days-56 days 0 38.0 % 2.0 hematocrit analysis 0.0 0 - 103230 2801
SR/Hsd change in RSNA to change in MAP ratio aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. kidney sympathetic nerve activity male 52 days-61 days 8 -2.84 %/mmHg 0.12 0.34 implanted wire electrode recording method 0.0 0 138423 2801
SR/Hsd mean arterial pressure at the midpoint of a range of renal sympathetic nerve activity artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. arterial blood pressure trait male 52 days-61 days 6 107.0 mmHg 3.0 7.35 vascular indwelling catheter method 0.0 0 138426 2801
SR/Hsd heart rate artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. heart pumping trait male 49 days-57 days 0 435.0 beats/min 19.0 vascular indwelling catheter method 0.0 0 138374 2801
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) (for 21 days) then ruthenium red (3 mg/kg) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -21.0 mmHg 2.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67265 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -39.0 mmHg 1.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67235 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then ruthenium red (3 mg/kg) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -5.0 mmHg 3.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67239 731
SR/Hsd plasma osmolality controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) then surgical denervation (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 300.6 umol/g 2.8 6.86 osmometry 0.0 0 p osmolality mosm/kg 102258 2682
SR/Hsd plasma triglyceride level controlled sodium content diet (0.3 %) then fasting (for 16 hours) Herrera VL, et al., Circ Res 2004 Mar 5; 94(4):446-52 blood triglyceride amount male 180 days 14 0.93 mmol/l 0.06 0.22 plasma triglyceride analysis 0 11893 204
SR/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 140.3 mmol/l 1.8 4.41 flame atomic emission spectrometry 0.0 0 102234 2682
SR/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 140.8 mmol/l 1.6 3.92 flame atomic emission spectrometry 0.0 0 102249 2682
SR/Hsd body weight standard diet Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. body mass male 49 days 8 213.0 g 2.4 6.8 body weighing method 0.0 0 102271 2683
SR/Hsd plasma chloride level aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. blood chloride amount male 49 days-56 days 0 100.0 mmol/l 3.0 chloride ion-selective electrode method 0.0 0 - 103227 2801
SR/Hsd body weight control condition Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. body mass male 88 days-94 days 10 316.0 g 8.0 25.3 body weighing method 0.0 0 107360 3077
SR/Hsd change in heart rate to change in mean arterial blood pressure ratio artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. heart pumping trait male 52 days-61 days 6 -2.13 beats/min/mmHg 0.19 0.47 vascular indwelling catheter method 0.0 0 change in heart rate to cchange in heart rate to change in mean arterial blood pressure ratio (CMO:0002036) 138434 2801
SR/Hsd heart rate aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. heart pumping trait male 49 days-56 days 0 454.0 beats/min 10.0 vascular indwelling catheter method 0.0 0 138355 2801
SR/Hsd mean arterial blood pressure aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. arterial blood pressure trait male 52 days-61 days 0 110.0 mmHg 2.0 vascular indwelling catheter method 0.0 0 138367 2801
SR/Hsd mean arterial blood pressure artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. arterial blood pressure trait male 52 days-61 days 0 103.0 mmHg 3.0 vascular indwelling catheter method 0.0 0 138378 2801
SR/Hsd hematocrit arterial catheter implantation (for 1 days) then controlled hemorrhage (for 0 hours) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. erythrocyte quantity male 89 days-95 days 10 42.5 % 0.9 2.85 microhematocrit tube assay with visual assessment 0.0 0 initial hematocrit, final hematocrit, change in hematocrit 107239 3077
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (for 21 days) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -39.0 mmHg 3.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67261 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then apamin (100 ug/kg) and charybdotoxin (100 ug/kg) and 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -13.0 mmHg 2.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67274 731
SR/Hsd cubic root of body weight to nasoanal length ratio controlled sodium content diet (0.3 %) then fasting (for 16 hours) Herrera VL, et al., Circ Res 2004 Mar 5; 94(4):446-52 body mass female 180 days 14 306.0 g/mm x 10000 2.0 7.48 body weighing method 0.0 0 67894 204
SR/Hsd heart rate artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. heart pumping trait male 49 days-56 days 0 437.0 beats/min 10.0 vascular indwelling catheter method 0.0 0 138354 2801
SR/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 139.6 mmol/l 2.1 5.14 flame atomic emission spectrometry 0.0 0 102233 2682
SR/Hsd plasma osmolality controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 301.3 umol/g 4.4 10.78 osmometry 0.0 0 102240 2682
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (for 21 days) then ruthenium red (3 mg/kg) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -31.0 mmHg 1.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67266 731
SR/Hsd plasma high density lipoprotein cholesterol level controlled sodium content diet (0.3 %) then fasting (for 16 hours) Herrera VL, et al., Circ Res 2004 Mar 5; 94(4):446-52 blood HDL cholesterol amount male 180 days 6 27.8 mg/dl 1.16 2.84 plasma high-density lipoprotein-cholesterol measurement test 0 11892 204
SR/Hsd mean arterial blood pressure standard diet Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. arterial blood pressure trait male 49 days 8 120.0 mmHg 1.06 3.0 tail cuff plethysmography 0.0 0 102267 2683
SR/Hsd body weight controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. body mass male 91 days 8 308.0 g 10.61 30.0 body weighing method 0.0 0 102273 2683
SR/Hsd plasma urotensin II level standard diet Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. blood urotensin II amount male 49 days 8 61.0 pg/ml 2.09 5.9 radioimmunoassay 0.0 0 102275 2683
SR/Hsd urine sodium level controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine sodium amount male 91 days 8 3.1 mmol/l 0.07 0.2 urine sodium analysis 0.0 0 102285 2683
SR/Hsd plasma chloride level artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. blood chloride amount male 49 days-56 days 0 102.0 mmol/l 2.0 chloride ion-selective electrode method 0.0 0 - 103226 2801
SR/Hsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89 days-95 days 10 124.0 mmHg 2.0 6.32 vascular fluid filled catheter 300.0 0 5-second intervals Initial MAP 107335 3077
SR/Hsd absolute change in hematocrit arterial catheter implantation (for 1 days) then controlled hemorrhage (between 0 and 0.4 hours) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. erythrocyte quantity male 89 days-95 days 10 11.8 % 0.8 2.53 microhematocrit tube assay with visual assessment 0.0 0 initial hematocrit, final hematocrit, change in hematocrit 107271 3077
SR/Hsd volume of blood removed to total prehemorrhagic blood volume ratio arterial catheter implantation (for 1 days) then controlled hemorrhage (for 0.4 hours) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. blood amount male 89 days-95 days 10 5.83 mL/100 g of body weight 56.0 % 0.4 1.26 body weighing method 0.0 0 volume of blood removed to total prehemorrhagic blood volume ratio (CMO:0003663) 109129 3077
SR/Hsd maximum body weight loss to initial body weight ratio arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. body mass male 89 days-95 days 10 2.2 % 0.7 2.21 body weighing method 0.0 arterial catheter implantation 1 days 107181 3077
SR/Hsd change in RSNA to change in MAP ratio artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. kidney sympathetic nerve activity male 52 days-61 days 6 -2.82 %/mmHg 0.14 0.34 implanted wire electrode recording method 0.0 0 range of ratio of change in renal sympathetic nerve activity (CMO:0003892) 138422 2801
SR/Hsd range of heart rate variation during variation of mean arterial blood pressure aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. heart pumping trait male 52 days-61 days 8 226.0 beats/min 17.0 48.08 vascular indwelling catheter method 0.0 0 change in heart rate to change in mean arterial blood pressure ratio (range) (CMO:0003896) 138431 2801
SR/Hsd mean arterial pressure at the midpoint of a range of renal sympathetic nerve activity aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. arterial blood pressure trait male 52 days-61 days 8 109.0 mmHg 3.0 8.49 vascular indwelling catheter method 0.0 0 138428 2801
SR/Hsd range of RSNA changes during variation of MAP artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. kidney sympathetic nerve activity male 52 days-61 days 6 185.0 % 12.0 29.39 implanted wire electrode recording method 0.0 0 range of ratio of change in renal sympathetic nerve activity (CMO:0003892) 138418 2801
SR/Hsd hematocrit arterial catheter implantation (for 1 days) then controlled hemorrhage (for 0.4 hours) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. erythrocyte quantity male 89 days-95 days 10 30.2 % 1.2 3.79 microhematocrit tube assay with visual assessment 0.0 0 initial hematocrit, final hematocrit, change in hematocrit 107255 3077
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then ruthenium red (3 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 15.0 mmHg 2.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67270 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) (for 21 days) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -28.0 mmHg 3.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67243 731
SR/Hsd calculated plasma low density lipoprotein cholesterol level controlled sodium content diet (0.3 %) then fasting (for 16 hours) Herrera VL, et al., Circ Res 2004 Mar 5; 94(4):446-52 blood LDL cholesterol amount female 180 days 6 14.67 mg/dl 3.47 8.51 plasma total cholesterol measurement test 0.0 0 11890 204
SR/Hsd plasma osmolality controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 299.6 umol/g 4.5 11.02 osmometry 0.0 0 p osmolality mosm/kg 102237 2682
SR/Hsd plasma osmolality controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood molecular composition trait male 91 days-119 days 6 302.4 umol/g 4.2 10.29 osmometry 0.0 0 p osmolality mosm/kg 102238 2682
SR/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 139.8 mmol/l 0.7 1.71 flame atomic emission spectrometry 0.0 0 102251 2682
SR/Hsd plasma urotensin II level controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. blood urotensin II amount male 91 days 8 60.0 pg/ml 2.26 6.4 radioimmunoassay 0.0 0 102277 2683
SR/Hsd urine urotensin II level to urine creatinine level ratio controlled sodium chloride content diet (8 %) (for 28 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine urotensin II amount male 77 days 8 181.3 ng/g 29.66 83.9 radioimmunoassay 0.0 0 102279 2683
SR/Hsd urine sodium level controlled sodium chloride content diet (8 %) (for 28 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. urine sodium amount male 77 days 8 3.8 mmol/l 0.21 0.6 urine sodium analysis 0.0 0 102283 2683
SR/Hsd creatinine clearance standard diet Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. glomerular filtration trait male 49 days 8 3.5 ml/min 0.07 0.2 urine creatinine analysis 0.0 0 102287 2683
SR/Hsd plasma sodium level artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. blood sodium amount male 49 days-56 days 0 145.0 mmol/l 3.0 sodium ion-selective electrode method 0.0 0 - 103218 2801
SR/Hsd hematocrit aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. erythrocyte quantity male 49 days-56 days 0 39.0 % 2.0 hematocrit analysis 0.0 0 - 103231 2801
SR/Hsd food intake weight to body weight ratio arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. eating behavior trait male 89 days-95 days 10 7.8 g/d/100g 0.5 1.58 food intake measuring method 0.0 arterial catheter implantation 1 days Food consumed (g) postsurgery per 100 g BW 107144 3077
SR/Hsd mean arterial blood pressure aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. arterial blood pressure trait male 52 days-61 days 0 105.0 mmHg 3.0 vascular indwelling catheter method 0.0 0 138379 2801
SR/Hsd body weight gain aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. body mass male 52 days-61 days 0 59.0 g 4.0 body weighing method 0.0 0 change from surgery weight (2wks) 138419 2801
SR/Hsd mean arterial pressure at the midpoint of a range of heart rates artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. arterial blood pressure trait male 52 days-61 days 6 106.0 mmHg 3.0 7.35 vascular indwelling catheter method 0.0 0 138438 2801
SR/Hsd mean arterial pressure at the midpoint of a range of heart rates aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. arterial blood pressure trait male 52 days-61 days 8 108.0 mmHg 3.0 8.49 vascular indwelling catheter method 0.0 0 138439 2801
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 -30.0 mmHg 2.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67237 731
SR/Hsd mean arterial blood pressure control condition (0.15 %) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35 days-56 days 0 106.0 mmHg 3.0 tail cuff plethysmography 0.0 0 DR strain is from Charles River Laboratory, Wilmington, MA 67233 731
SR/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 140.4 mmol/l 1.4 3.43 flame atomic emission spectrometry 0.0 0 102236 2682
SR/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) then surgical denervation (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91 days-119 days 6 140.7 mmol/l 0.9 2.2 flame atomic emission spectrometry 0.0 0 102252 2682
SR/Hsd range of RSNA changes during variation of MAP aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. kidney sympathetic nerve activity male 52 days-61 days 8 180.0 % 14.0 39.6 implanted wire electrode recording method 0.0 0 range of ratio of change in renal sympathetic nerve activity (CMO:0003892) 103215 2801
SR/Hsd plasma sodium level aldosterone (22.5 ng/hr) (for 14 days) and artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. blood sodium amount male 49 days-56 days 0 146.0 mmol/l 2.0 sodium ion-selective electrode method 0.0 0 - 103219 2801
SR/Hsd plasma potassium level artificial cerebrospinal fluid with 0.15 M sodium (4.4-4.6 ul/hr) (for 14 days) Huang BS, et al., Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H517-24. doi: 10.1152/ajpheart.00651.2004. Epub 2004 Sep 30. blood potassium amount male 49 days-56 days 0 5.1 mmol/l 0.2 potassium ion-selective electrode method 0.0 0 - 103222 2801