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Rat Strains

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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1Condition 2Condition 3aCondition 3b
4body weightWKYfemale200.8gcontrolled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days)12589controlled sodium content diet (0.4 %) (for 122 days)controlled sodium content diet (1.4 %) (for 210 days)
4body weightWKYmale318gcontrolled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days)12588controlled sodium content diet (0.4 %) (for 122 days)controlled sodium content diet (1.4 %) (for 210 days)
16body weightWKYmale261gunilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days)107448unilateral nephrectomy (for 150 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 136 days)
16body weightWKYmale267gunilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 136 days) and bosentan (100 mg/kg/d) (for 136 days)107449unilateral nephrectomy (for 150 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 136 days)bosentan (100 mg/kg/d) (for 136 days)
11body weightWKYmale408gunilateral nephrectomy (for 150 days) then vehicle control condition107445unilateral nephrectomy (for 150 days)vehicle control condition
17body weightWKYmale274gunilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 136 days)107447unilateral nephrectomy (for 150 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 136 days)
17body weightWKYmale256gunilateral nephrectomy (for 150 days) then streptozotocin (35 mg/kg) then vehicle control condition107446unilateral nephrectomy (for 150 days)streptozotocin (35 mg/kg) vehicle control condition
32body weightWKYmale574gleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days)100275left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ramipril (1 mg/kg/d) (for 182 days)
16body weightWKYmale599gleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days)100274left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)
5body weightWKYmale562gsham surgical control condition (for 224 days)100273sham surgical control condition (for 224 days)
30body weightWKYmale617gleft anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days)100272left anterior descending coronary artery occlusion (for 196 days)vehicle control condition (for 182 days)
20body weightWKYmale583gleft anterior descending coronary artery occlusion (for 196 days) then furosemide (10 ml/kg/d) (for 182 days)100271left anterior descending coronary artery occlusion (for 196 days)furosemide (10 ml/kg/d) (for 182 days)
12body weightWKYmale566gsham surgical control condition (for 196 days)100270sham surgical control condition (for 196 days)
30body weightWKYmale225gleft anterior descending coronary artery occlusion then vehicle control condition100269left anterior descending coronary artery occlusionvehicle control condition
20body weightWKYmale225gleft anterior descending coronary artery occlusion then furosemide100268left anterior descending coronary artery occlusionfurosemide
12body weightWKYmale223gsham surgical control condition100267sham surgical control condition
5body weightWKYmale260gnaive control condition (for 0 hours)103476naive control condition (for 0 hours)
12body weightWKYmale312gcontrolled enalapril content drinking water (50 mg/l) (between 63 and 77 days) then puromycin aminonucleoside (50 mg/kg) 100396controlled enalapril content drinking water (50 mg/l) (between 63 and 77 days)puromycin aminonucleoside (50 mg/kg)
12body weightWKYmale323gpuromycin aminonucleoside (50 mg/kg) 100395puromycin aminonucleoside (50 mg/kg)
11body weightWKYmale319g0.9% sodium chloride solution (3 ml) 1003940.9% sodium chloride solution (3 ml)
10body weightWKYmale241g0.9% sodium chloride solution (3 ml) 1003910.9% sodium chloride solution (3 ml)
9body weightWKYmale395gcontrolled enalapril content drinking water (50 mg/l) (for 497 days) then puromycin aminonucleoside (50 mg/kg) 100435controlled enalapril content drinking water (50 mg/l) (for 497 days)puromycin aminonucleoside (50 mg/kg)
8body weightWKYmale418gpuromycin aminonucleoside (50 mg/kg) 100434puromycin aminonucleoside (50 mg/kg)
9body weightWKYmale412g0.9% sodium chloride solution (3 ml) 1004330.9% sodium chloride solution (3 ml)
8body weightWKYmale305gcontrolled enalapril content drinking water (50 mg/l) (between 63 and 77 days) then puromycin aminonucleoside (50 mg/kg) 100432controlled enalapril content drinking water (50 mg/l) (between 63 and 77 days)puromycin aminonucleoside (50 mg/kg)
9body weightWKYmale297gpuromycin aminonucleoside (50 mg/kg) 100431puromycin aminonucleoside (50 mg/kg)
8body weightWKYmale317g0.9% sodium chloride solution (3 ml) 1004300.9% sodium chloride solution (3 ml)
5body weightWKYmale245gcontrolled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) 100429controlled enalapril content drinking water (50 mg/l) (for 22 days)puromycin aminonucleoside (50 mg/kg)
7body weightWKYmale245gpuromycin aminonucleoside (50 mg/kg) 100428puromycin aminonucleoside (50 mg/kg)
9body weightWKYmale244g0.9% sodium chloride solution (3 ml) 1004270.9% sodium chloride solution (3 ml)
10body weightWKYmale241gcontrolled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) 100393controlled enalapril content drinking water (50 mg/l) (for 22 days)puromycin aminonucleoside (50 mg/kg)
11body weightWKYmale249gpuromycin aminonucleoside (50 mg/kg) 100392puromycin aminonucleoside (50 mg/kg)
6body weightWKYmale229gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days)99939unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)bosentan (100 mg/kg/d) (for 14 days)
8body weightWKYmale233gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days)99938unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)
8body weightWKYmale236gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days)99937unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 14 days)
8body weightWKYmale215gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition99936unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) vehicle control condition
7body weightWKYmale268gunilateral nephrectomy (for 28 days) then vehicle control condition99935unilateral nephrectomy (for 28 days)vehicle control condition
18body weightWKYmale436gin utero condition (30 % of calories) (for 22 days)99076in utero condition (30 % of calories) (for 22 days)
17body weightWKYmale454gcontrolled in utero environment (100 % of calories) (for 22 days)99075controlled in utero environment (100 % of calories) (for 22 days)
36body weightWKYnot specified4.91gin utero condition (30 % of calories) (for 22 days)99074in utero condition (30 % of calories) (for 22 days)
26body weightWKYnot specified6.64gcontrolled in utero environment (100 % of calories) (for 22 days)99073controlled in utero environment (100 % of calories) (for 22 days)
10body weightWKYmale286.6gstreptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 null) 99112streptozotocin (60 mg/kg) benazepril (10 mg/kg/d) gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 null)
10body weightWKYmale287.24gstreptozotocin (60 mg/kg) then benazepril (10 mg/kg/d) 99111streptozotocin (60 mg/kg) benazepril (10 mg/kg/d)
10body weightWKYmale295.56gstreptozotocin (60 mg/kg) then gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 null) 99110streptozotocin (60 mg/kg) gene transfer of the murine angiotensin I converting enzyme 2 gene using an adenovirus vector (40000000000 null)
10body weightWKYmale261.43gstreptozotocin (60 mg/kg) then gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (40000000000 null) 99109streptozotocin (60 mg/kg) gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (40000000000 null)
10body weightWKYmale259.65gstreptozotocin (60 mg/kg) 99108streptozotocin (60 mg/kg)
10body weightWKYmale450.39gvehicle control condition (1 null) 99107vehicle control condition (1 null)
7body weightWKYmale373.6gnaive control condition99849naive control condition