WKY/NCrl |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
salidroside (40 mg/kg) (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
-7.1 |
null |
0.04 |
0.11 |
wire myography |
|
0 |
|
103587 |
2827 |
WKY/NCrl |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
vehicle control condition (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
-7.6 |
null |
0.05 |
0.13 |
wire myography |
0.0 |
0 |
|
103602 |
2827 |
WKY/NCrl |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
salidroside (40 mg/kg) (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
98.36 |
% |
0.98 |
2.59 |
wire myography |
0.0 |
0 |
|
103599 |
2827 |
WKY/NCrl |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
salidroside (40 mg/kg) (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
-8.21 |
null |
0.07 |
0.19 |
wire myography |
0.0 |
0 |
|
103611 |
2827 |
WKY/NCrl |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
salidroside (40 mg/kg) (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
90.64 |
% |
2.0 |
5.29 |
wire myography |
0.0 |
0 |
|
103591 |
2827 |
WKY/NCrl |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
salidroside (40 mg/kg) (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
-8.04 |
null |
0.04 |
0.12 |
wire myography |
0.0 |
0 |
|
103595 |
2827 |
WKY/NCrl |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
salidroside (40 mg/kg) (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
-7.72 |
null |
0.03 |
0.08 |
wire myography |
0.0 |
0 |
|
103603 |
2827 |
WKY/NCrl |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
vehicle control condition (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
-8.06 |
null |
0.05 |
0.13 |
wire myography |
0.0 |
0 |
|
103594 |
2827 |
WKY/NCrl |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
vehicle control condition (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
97.56 |
% |
1.02 |
2.7 |
wire myography |
0.0 |
0 |
|
103598 |
2827 |
WKY/NCrl |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
salidroside (40 mg/kg) (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
96.2 |
% |
1.31 |
3.47 |
wire myography |
0.0 |
0 |
|
103607 |
2827 |
WKY/NCrl |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
vehicle control condition (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
99.75 |
% |
2.32 |
6.14 |
wire myography |
0.0 |
0 |
|
103606 |
2827 |
WKY/NCrl |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
salidroside (40 mg/kg) (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
90.13 |
% |
1.55 |
4.1 |
wire myography |
0.0 |
0 |
|
103615 |
2827 |
WKY/NCrl |
norepinephrine-induced blood vessel contractile force expressed as percent of force of contraction to KCL |
control condition |
Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. |
vasoconstriction trait |
male |
84 days
| 10 |
105.7 |
% |
11.0 |
34.79 |
wire myography |
0.0 |
0 |
norepinephrine-induced blood vessel contractile force expressed as percent of force at baseline (CMO:0003676) |
109377 |
3141 |
WKY/NCrl |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
vehicle control condition (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
-8.15 |
null |
0.09 |
0.24 |
wire myography |
0.0 |
0 |
|
103610 |
2827 |
WKY/NCrl |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
control condition |
Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. |
vasodilation trait |
male |
84 days
| 10 |
81.1 |
% |
3.0 |
9.49 |
wire myography |
0.0 |
0 |
|
109367 |
3141 |
WKY/NCrl |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
vehicle control condition (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
-7.07 |
null |
0.05 |
0.14 |
wire myography |
|
0 |
|
103586 |
2827 |
WKY/NCrl |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
vehicle control condition (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
89.88 |
% |
2.56 |
6.77 |
wire myography |
0.0 |
0 |
|
103590 |
2827 |
WKY/NCrl |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
vehicle control condition (for 28 days) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
vasodilation trait |
male |
168 days
| 7 |
96.54 |
% |
1.9 |
5.03 |
wire myography |
0.0 |
0 |
|
103614 |
2827 |
WKY/NCrl |
negative logarithm of the molar concentration of norepinephrine at which the force of blood vessel contraction is half the maximum value |
control condition |
Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. |
vasoconstriction trait |
male |
84 days
| 10 |
7.8 |
null |
0.2 |
0.63 |
wire myography |
0.0 |
0 |
logarithm of the concentration of norepinephrine at which the force of blood vessel contraction is half the maximum value (CMO:0003677) |
109382 |
3141 |