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PhenoMiner Database Result        View data table  |  Download data table  |  View expanded data table        


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Rat Strains

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Experimental Conditions

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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1aCondition 1bCondition 2Condition 3aCondition 3b
2plasma campesterol levelCrl:SDnot specified1.3mg/dlcontrol condition70515control condition
2liver campesterol levelCrl:SDnot specified0.03mg/gcontrol condition70520control condition
2brain cholesterol levelCrl:SDnot specified10.95mg/gcontrol condition70524control condition
2liver sitosterol levelCrl:SDnot specified0.03mg/gcontrol condition70537control condition
2plasma phytosterol levelCrl:SDnot specified3.3mg/dlcontrol condition70545control condition
2liver phytosterol levelCrl:SDnot specified0.05mg/gcontrol condition70550control condition
2brain phytosterol levelCrl:SDnot specified0.03mg/gcontrol condition70554control condition
2plasma total cholesterol levelCrl:SDnot specified54.6mg/dlcontrol condition70158control condition
2liver cholesterol levelCrl:SDnot specified1.72mg/gcontrol condition70163control condition
2brain campesterol levelCrl:SDnot specified0.02mg/gcontrol condition70528control condition
2plasma sitosterol levelCrl:SDnot specified1.95mg/dlcontrol condition70532control condition
2brain sitosterol levelCrl:SDnot specified0.02mg/gcontrol condition70541control condition
12blood glucose levelCrl:SDfemale81mg/dlcontrolled fructose content drinking water (5 %) (for 63 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 63 days)75793controlled fructose content drinking water (5 %) (for 63 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 63 days)
12blood glucose levelCrl:SDfemale79.2mg/dlcontrolled fructose content drinking water (5 %) (for 63 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 63 days)75794controlled fructose content drinking water (5 %) (for 63 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 63 days)
12total body fat volumeCrl:SDfemale28.2cm3controlled ethanol content drinking water (1 %) (for 70 days)75812controlled ethanol content drinking water (1 %) (for 70 days)
12total body fat volumeCrl:SDfemale29.8cm3controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75813controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12total body fat volumeCrl:SDfemale29.6cm3controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75814controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12total body fat volumeCrl:SDfemale28.9cm3controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75815controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12total body fat volumeCrl:SDfemale31.7cm3controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75816controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12whole body subcutaneous fat volumeCrl:SDfemale14.4mlcontrolled ethanol content drinking water (1 %) (for 70 days)75817controlled ethanol content drinking water (1 %) (for 70 days)
12whole body subcutaneous fat volumeCrl:SDfemale15.4mlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75818controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12whole body subcutaneous fat volumeCrl:SDfemale15.6mlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75819controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12whole body subcutaneous fat volumeCrl:SDfemale15.1mlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75820controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12whole body subcutaneous fat volumeCrl:SDfemale16.4mlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75821controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12whole body visceral fat volumeCrl:SDfemale13.9mlcontrolled ethanol content drinking water (1 %) (for 70 days)75822controlled ethanol content drinking water (1 %) (for 70 days)
12whole body visceral fat volumeCrl:SDfemale14.3mlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75823controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12whole body visceral fat volumeCrl:SDfemale13.9mlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75824controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12whole body visceral fat volumeCrl:SDfemale13.8mlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75825controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12whole body visceral fat volumeCrl:SDfemale15.3mlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75826controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12whole body lean tissue volumeCrl:SDfemale95.5cm3controlled ethanol content drinking water (1 %) (for 70 days)75827controlled ethanol content drinking water (1 %) (for 70 days)
12whole body lean tissue volumeCrl:SDfemale95.2cm3controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75828controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12whole body lean tissue volumeCrl:SDfemale96.6cm3controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75829controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12whole body lean tissue volumeCrl:SDfemale95.4cm3controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75830controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12whole body lean tissue volumeCrl:SDfemale96.1cm3controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75831controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12food intake rateCrl:SDfemale10.8g/dcontrolled ethanol content drinking water (1 %) (for 7 days)75717controlled ethanol content drinking water (1 %) (for 7 days)
12food intake rateCrl:SDfemale10g/dcontrolled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days)75719controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days)
12bisphenol A in fructose drink intake rateCrl:SDfemale20.4g/dcontrolled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days)75723controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days)
12food intake rateCrl:SDfemale8.7g/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)75741controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
12body weightCrl:SDfemale175.1gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75756controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12ethanol drink intake rateCrl:SDfemale10.8g/dcontrolled ethanol content drinking water (1 %) (for 70 days)75725controlled ethanol content drinking water (1 %) (for 70 days)
12bisphenol A in fructose drink intake rateCrl:SDfemale33g/dcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75727controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12food intake rateCrl:SDfemale8.3g/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)75740controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
12food intake rateCrl:SDfemale9.3g/dcontrolled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days)75742controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days)
12body weightCrl:SDfemale84.7gcontrolled fructose content drinking water (5 %) and controlled bisphenol A content drinking water (0.025 mg/l) 75749controlled fructose content drinking water (5 %) controlled bisphenol A content drinking water (0.025 mg/l)
12liver weightCrl:SDfemale5.4gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75775controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12plasma total cholesterol levelCrl:SDfemale115.83mg/dlcontrolled ethanol content drinking water (1 %) (for 70 days)75781controlled ethanol content drinking water (1 %) (for 70 days)
12plasma total cholesterol levelCrl:SDfemale119.691mg/dlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75782controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12plasma total cholesterol levelCrl:SDfemale123.552mg/dlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75783controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
11plasma total cholesterol levelCrl:SDfemale119.691mg/dlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75784controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12plasma triglyceride levelCrl:SDfemale1.7mmol/lcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75788controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12blood glucose levelCrl:SDfemale82.8mg/dlcontrolled ethanol content drinking water (1 %) (for 63 days)75791controlled ethanol content drinking water (1 %) (for 63 days)
12blood glucose levelCrl:SDfemale81mg/dlcontrolled fructose content drinking water (5 %) (for 63 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 63 days)75795controlled fructose content drinking water (5 %) (for 63 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 63 days)
12food intake rateCrl:SDfemale10.1g/dcontrolled fructose content drinking water (5 %) (for 7 days) and controlled ethanol content drinking water (1 %) (for 7 days)75718controlled fructose content drinking water (5 %) (for 7 days)controlled ethanol content drinking water (1 %) (for 7 days)
12food intake rateCrl:SDfemale9.6g/dcontrolled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days)75720controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days)
12ethanol drink intake rateCrl:SDfemale11.6g/dcontrolled ethanol content drinking water (1 %) (for 7 days)75721controlled ethanol content drinking water (1 %) (for 7 days)
12fructose drink intake rateCrl:SDfemale20.8g/dcontrolled fructose content drinking water (5 %) (for 7 days) and controlled ethanol content drinking water (1 %) (for 7 days)75722controlled fructose content drinking water (5 %) (for 7 days)controlled ethanol content drinking water (1 %) (for 7 days)
12bisphenol A in fructose drink intake rateCrl:SDfemale21.8g/dcontrolled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days)75724controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days)
12fructose drink intake rateCrl:SDfemale32g/dcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75726controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12bisphenol A in fructose drink intake rateCrl:SDfemale30.1g/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)75732controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
12food intake rateCrl:SDfemale10g/dcontrolled ethanol content drinking water (1 %) (for 70 days)75733controlled ethanol content drinking water (1 %) (for 70 days)
12food intake rateCrl:SDfemale8.3g/dcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75734controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12food intake rateCrl:SDfemale7.8g/dcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75736controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12food intake rateCrl:SDfemale10.2g/dcontrolled ethanol content drinking water (1 %) (between 7 and 70 days)75737controlled ethanol content drinking water (1 %) (between 7 and 70 days)
12food intake rateCrl:SDfemale8.3g/dcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75743controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12bisphenol A in fructose drink intake rateCrl:SDfemale19.8g/dcontrolled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days)75744controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days)
12body weightCrl:SDfemale92.6gcontrolled ethanol content drinking water (1 %) 75747controlled ethanol content drinking water (1 %)
12body weightCrl:SDfemale87.8gcontrolled fructose content drinking water (5 %) and controlled ethanol content drinking water (1 %) 75748controlled fructose content drinking water (5 %) controlled ethanol content drinking water (1 %)
12body weightCrl:SDfemale88.7gcontrolled fructose content drinking water (5 %) and controlled bisphenol A content drinking water (0.25 mg/l) 75750controlled fructose content drinking water (5 %) controlled bisphenol A content drinking water (0.25 mg/l)
12body weightCrl:SDfemale88.3gcontrolled fructose content drinking water (5 %) and controlled bisphenol A content drinking water (2.5 mg/l) 75751controlled fructose content drinking water (5 %) controlled bisphenol A content drinking water (2.5 mg/l)
11body weightCrl:SDfemale172.3gcontrolled ethanol content drinking water (1 %) (for 70 days)75752controlled ethanol content drinking water (1 %) (for 70 days)
12body weightCrl:SDfemale171.7gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75753controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12body weightCrl:SDfemale173.7gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75754controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12body weightCrl:SDfemale172.9gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75755controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12body weight gainCrl:SDfemale80.1gcontrolled ethanol content drinking water (1 %) (for 70 days)75757controlled ethanol content drinking water (1 %) (for 70 days)
12body weight gainCrl:SDfemale86.2gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75758controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12body weight gainCrl:SDfemale88.3gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75759controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12body weight gainCrl:SDfemale82.6gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75760controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12body weight gainCrl:SDfemale86.4gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75761controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12liver weightCrl:SDfemale4.8gcontrolled ethanol content drinking water (1 %) (for 70 days)75771controlled ethanol content drinking water (1 %) (for 70 days)
12liver weightCrl:SDfemale5.1gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75772controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12liver weightCrl:SDfemale5.6gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75773controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12liver weightCrl:SDfemale5.6gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75774controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12liver weight to body weight ratioCrl:SDfemale28g/kgcontrolled ethanol content drinking water (1 %) (for 70 days)75776controlled ethanol content drinking water (1 %) (for 70 days)
12liver weight to body weight ratioCrl:SDfemale30g/kgcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75777controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12liver weight to body weight ratioCrl:SDfemale32g/kgcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75778controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12liver weight to body weight ratioCrl:SDfemale32g/kgcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75779controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12liver weight to body weight ratioCrl:SDfemale31g/kgcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75780controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12plasma total cholesterol levelCrl:SDfemale127.413mg/dlcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75785controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12plasma triglyceride levelCrl:SDfemale0.88mmol/lcontrolled ethanol content drinking water (1 %) (for 70 days)75786controlled ethanol content drinking water (1 %) (for 70 days)
12plasma triglyceride levelCrl:SDfemale1.3mmol/lcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75787controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
11plasma triglyceride levelCrl:SDfemale1.7mmol/lcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75789controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12plasma triglyceride levelCrl:SDfemale1.6mmol/lcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75790controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12blood glucose levelCrl:SDfemale84.6mg/dlcontrolled fructose content drinking water (5 %) (for 63 days) and controlled ethanol content drinking water (1 %) (for 63 days)75792controlled fructose content drinking water (5 %) (for 63 days)controlled ethanol content drinking water (1 %) (for 63 days)
12liver fat volume to total liver volume ratioCrl:SDfemale5.5%controlled ethanol content drinking water (1 %) (for 70 days)75832controlled ethanol content drinking water (1 %) (for 70 days)
11liver fat volume to total liver volume ratioCrl:SDfemale5.6%controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75833controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12liver fat volume to total liver volume ratioCrl:SDfemale6.4%controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75834controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12liver fat volume to total liver volume ratioCrl:SDfemale7%controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75835controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12liver fat volume to total liver volume ratioCrl:SDfemale6.9%controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75836controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12left renal fat pad weightCrl:SDfemale0.74gcontrolled ethanol content drinking water (1 %) (for 70 days)75837controlled ethanol content drinking water (1 %) (for 70 days)
12left renal fat pad weightCrl:SDfemale0.86gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75838controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12left renal fat pad weightCrl:SDfemale0.77gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75839controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12left renal fat pad weightCrl:SDfemale0.76gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75840controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12left renal fat pad weightCrl:SDfemale0.88gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75841controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12left renal fat pad weight to body weight ratioCrl:SDfemale0.43%controlled ethanol content drinking water (1 %) (for 70 days)75842controlled ethanol content drinking water (1 %) (for 70 days)
11left renal fat pad weight to body weight ratioCrl:SDfemale0.5%controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75843controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12left renal fat pad weight to body weight ratioCrl:SDfemale0.44%controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75844controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12left renal fat pad weight to body weight ratioCrl:SDfemale0.44%controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75845controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12left renal fat pad weight to body weight ratioCrl:SDfemale0.5%controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75846controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12bisphenol A in fructose drink intake rateCrl:SDfemale36.8g/dcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75728controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12ethanol drink intake rateCrl:SDfemale11.5g/dcontrolled ethanol content drinking water (1 %) 75729controlled ethanol content drinking water (1 %)
12fructose drink intake rateCrl:SDfemale28.3g/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days)75730controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled ethanol content drinking water (1 %) (between 7 and 70 days)
12bisphenol A in fructose drink intake rateCrl:SDfemale28.1g/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)75731controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
12food intake rateCrl:SDfemale7.9g/dcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75735controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12food intake rateCrl:SDfemale8.7g/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days)75738controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled ethanol content drinking water (1 %) (between 7 and 70 days)
12food intake rateCrl:SDfemale8.5g/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)75739controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
12bisphenol A in fructose drink intake rateCrl:SDfemale29.4g/dcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75745controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12bisphenol A in fructose drink intake rateCrl:SDfemale24.7g/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)75746controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
12body weightCrl:SDfemale148.4gcontrolled ethanol content drinking water (1 %) (for 70 days)75796controlled ethanol content drinking water (1 %) (for 70 days)
12body weightCrl:SDfemale149.1gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75797controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
12body weightCrl:SDfemale151.5gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75798controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
12body weightCrl:SDfemale149.6gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75799controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
12body weightCrl:SDfemale153.1gcontrolled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75800controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
12fructose drink calorie intake rateCrl:SDfemale0kcal/dcontrolled ethanol content drinking water (1 %) (between 7 and 70 days)76100controlled ethanol content drinking water (1 %) (between 7 and 70 days)
12fructose drink calorie intake rateCrl:SDfemale5.7kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days)76101controlled fructose content drinking water (5 %) (between 7 and 70 days)
12fructose drink calorie intake rateCrl:SDfemale5.6kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)76102controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
12fructose drink calorie intake rateCrl:SDfemale6kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)76103controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
12fructose drink calorie intake rateCrl:SDfemale4.9kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)76104controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
12food calorie intake rateCrl:SDfemale28.9kcal/dcontrolled ethanol content drinking water (1 %) (between 7 and 70 days)76105controlled ethanol content drinking water (1 %) (between 7 and 70 days)
12food calorie intake rateCrl:SDfemale24.6kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days)76106controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled ethanol content drinking water (1 %) (between 7 and 70 days)
12food calorie intake rateCrl:SDfemale24.1kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)76107controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
12food calorie intake rateCrl:SDfemale23.5kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)76108controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
12food calorie intake rateCrl:SDfemale24.6kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)76109controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
12total calorie intake rateCrl:SDfemale28.9kcal/dcontrolled ethanol content drinking water (1 %) (between 7 and 70 days)76110controlled ethanol content drinking water (1 %) (between 7 and 70 days)
12total calorie intake rateCrl:SDfemale30.3kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days)76111controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled ethanol content drinking water (1 %) (between 7 and 70 days)
12total calorie intake rateCrl:SDfemale29.7kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)76112controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
12total calorie intake rateCrl:SDfemale29.5kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)76113controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
12total calorie intake rateCrl:SDfemale29.5kcal/dcontrolled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)76114controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
N/Aplasma insulin levelCrl:SDmale53mU/lcontrolled fructose content diet (66 %) (between 14 and 28 days)75879controlled fructose content diet (66 %) (between 14 and 28 days)
8plasma insulin levelCrl:SDmale68mU/lcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days)75880controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)insulin (2 U/kg/d) (for 14 days)
9plasma insulin levelCrl:SDmale51mU/lcontrolled fructose content diet (66 %) (between 14 and 28 days)75847controlled fructose content diet (66 %) (between 14 and 28 days)
8plasma insulin levelCrl:SDmale33mU/lcontrol condition75848control condition
10plasma insulin levelCrl:SDmale32mU/lcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75849controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
8plasma insulin levelCrl:SDmale26mU/lcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75850controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
9systolic blood pressureCrl:SDmale159mmHgcontrolled fructose content diet (66 %) (between 14 and 28 days)75851controlled fructose content diet (66 %) (between 14 and 28 days)
8systolic blood pressureCrl:SDmale141mmHgcontrol condition75852control condition
10systolic blood pressureCrl:SDmale143mmHgcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75853controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
8systolic blood pressureCrl:SDmale142mmHgcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75854controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
9plasma glucose levelCrl:SDmale117mg/dlcontrolled fructose content diet (66 %) (between 14 and 28 days)75855controlled fructose content diet (66 %) (between 14 and 28 days)
8plasma glucose levelCrl:SDmale111.6mg/dlcontrol condition75856control condition
10plasma glucose levelCrl:SDmale111.6mg/dlcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75857controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
8plasma glucose levelCrl:SDmale111.6mg/dlcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75858controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
9plasma glucose levelCrl:SDmale108mg/dlcontrolled fructose content diet (66 %) 75859controlled fructose content diet (66 %)
8plasma glucose levelCrl:SDmale118.8mg/dlcontrol condition75860control condition
10plasma glucose levelCrl:SDmale104.4mg/dlcontrolled metformin content drinking water (350-500 mg/kg/d) then controlled fructose content diet (66 %) 75861controlled metformin content drinking water (350-500 mg/kg/d) controlled fructose content diet (66 %)
8plasma glucose levelCrl:SDmale106.2mg/dlcontrolled metformin content drinking water (350-500 mg/kg/d) 75862controlled metformin content drinking water (350-500 mg/kg/d)
9water drink intake rateCrl:SDmale39ml/dcontrolled fructose content diet (66 %) (between 14 and 28 days)75863controlled fructose content diet (66 %) (between 14 and 28 days)
8water drink intake rateCrl:SDmale43ml/dcontrol condition75864control condition
10metformin drink intake rateCrl:SDmale35ml/dcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75865controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
8metformin drink intake rateCrl:SDmale37ml/dcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75866controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
9water drink intake rateCrl:SDmale34ml/dcontrolled fructose content diet (66 %) 75867controlled fructose content diet (66 %)
8water drink intake rateCrl:SDmale35ml/dcontrol condition75868control condition
10metformin drink intake rateCrl:SDmale33ml/dcontrolled metformin content drinking water (350-500 mg/kg/d) then controlled fructose content diet (66 %) 75869controlled metformin content drinking water (350-500 mg/kg/d) controlled fructose content diet (66 %)
8metformin drink intake rateCrl:SDmale31ml/dcontrolled metformin content drinking water (350-500 mg/kg/d) 75870controlled metformin content drinking water (350-500 mg/kg/d)
8plasma glucagon levelCrl:SDmale353pmol/lcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75923controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
8plasma glucagon levelCrl:SDmale402pmol/lcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days)75924controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)insulin (2 U/kg/d) (for 14 days)
N/Asystolic blood pressureCrl:SDmale160mmHgcontrolled fructose content diet (66 %) (between 14 and 28 days)75925controlled fructose content diet (66 %) (between 14 and 28 days)
8systolic blood pressureCrl:SDmale158mmHgcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days)75926controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)insulin (2 U/kg/d) (for 14 days)
9food intake rateCrl:SDmale26g/dcontrolled fructose content diet (66 %) (between 14 and 28 days)75871controlled fructose content diet (66 %) (between 14 and 28 days)
8food intake rateCrl:SDmale28g/dcontrol condition75872control condition
10food intake rateCrl:SDmale24g/dcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75873controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
8food intake rateCrl:SDmale24g/dcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75874controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
9food intake rateCrl:SDmale19g/dcontrolled fructose content diet (66 %) 75875controlled fructose content diet (66 %)
8food intake rateCrl:SDmale18g/dcontrol condition75876control condition
10food intake rateCrl:SDmale18g/dcontrolled metformin content drinking water (350-500 mg/kg/d) then controlled fructose content diet (66 %) 75877controlled metformin content drinking water (350-500 mg/kg/d) controlled fructose content diet (66 %)
8food intake rateCrl:SDmale17g/dcontrolled metformin content drinking water (350-500 mg/kg/d) 75878controlled metformin content drinking water (350-500 mg/kg/d)
8plasma glucose levelCrl:SDmale102.6mg/dlcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75921controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
8plasma glucose levelCrl:SDmale82.8mg/dlcontrolled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days)75922controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)insulin (2 U/kg/d) (for 14 days)
6kidney glomerulus volumeCrl:SDmale3.14x 10E6 um3streptozotocin (60 mg/kg/d) then insulin (for 308 days) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 175 days)100772streptozotocin (60 mg/kg/d) insulin (for 308 days)anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 175 days)
6kidney glomerulus volumeCrl:SDmale2.18x 10E6 um3streptozotocin (60 mg/kg/d) then insulin (for 308 days) then anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 175 days)100773streptozotocin (60 mg/kg/d) insulin (for 308 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 175 days)
6kidney glomerulus volumeCrl:SDmale2.06x 10E6 um3streptozotocin (60 mg/kg/d) then insulin (for 308 days) then enalapril (15 mg/l) (for 175 days)100774streptozotocin (60 mg/kg/d) insulin (for 308 days)enalapril (15 mg/l) (for 175 days)
5kidney glomerulus volumeCrl:SDmale2.36x 10E6 um3control condition100775control condition
6number of podocytes per kidney glomerulusCrl:SDmale158.59streptozotocin (60 mg/kg/d) then insulin (for 308 days) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 175 days)100776streptozotocin (60 mg/kg/d) insulin (for 308 days)anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 175 days)
6number of podocytes per kidney glomerulusCrl:SDmale182.12streptozotocin (60 mg/kg/d) then insulin (for 308 days) then anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 175 days)100777streptozotocin (60 mg/kg/d) insulin (for 308 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 175 days)
6number of podocytes per kidney glomerulusCrl:SDmale201.08streptozotocin (60 mg/kg/d) then insulin (for 308 days) then enalapril (15 mg/l) (for 175 days)100778streptozotocin (60 mg/kg/d) insulin (for 308 days)enalapril (15 mg/l) (for 175 days)
5number of podocytes per kidney glomerulusCrl:SDmale212.59control condition100779control condition
6kidney glomerulus volumeCrl:SDmale3.14x 10E6 um3streptozotocin (60 mg/kg/d) then insulin (for 371 days) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 63 days)100784streptozotocin (60 mg/kg/d) insulin (for 371 days)anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 63 days)
6kidney glomerulus volumeCrl:SDmale2.44x 10E6 um3streptozotocin (60 mg/kg/d) then insulin (for 371 days) then anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)100785streptozotocin (60 mg/kg/d) insulin (for 371 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)
6kidney glomerulus volumeCrl:SDmale2.4x 10E6 um3streptozotocin (60 mg/kg/d) then insulin (for 371 days) then enalapril (15 mg/l) (for 63 days)100786streptozotocin (60 mg/kg/d) insulin (for 371 days)enalapril (15 mg/l) (for 63 days)
6kidney glomerulus volumeCrl:SDmale2.37x 10E6 um3streptozotocin (60 mg/kg/d) then insulin (for 371 days) then enalapril (15 mg/l) (for 63 days) and anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)100787streptozotocin (60 mg/kg/d) insulin (for 371 days)enalapril (15 mg/l) (for 63 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)
6kidney glomerulus volumeCrl:SDmale2.36x 10E6 um3control condition100788control condition
6number of podocytes per kidney glomerulusCrl:SDmale158.33streptozotocin (60 mg/kg/d) then insulin (for 371 days) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 63 days)100789streptozotocin (60 mg/kg/d) insulin (for 371 days)anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 63 days)
6number of podocytes per kidney glomerulusCrl:SDmale178.53streptozotocin (60 mg/kg/d) then insulin (for 371 days) then anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)100790streptozotocin (60 mg/kg/d) insulin (for 371 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)
6number of podocytes per kidney glomerulusCrl:SDmale179.66streptozotocin (60 mg/kg/d) then insulin (for 371 days) then enalapril (15 mg/l) (for 63 days)100791streptozotocin (60 mg/kg/d) insulin (for 371 days)enalapril (15 mg/l) (for 63 days)
6number of podocytes per kidney glomerulusCrl:SDmale201.84streptozotocin (60 mg/kg/d) then insulin (for 371 days) then enalapril (15 mg/l) (for 63 days) and anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)100792streptozotocin (60 mg/kg/d) insulin (for 371 days)enalapril (15 mg/l) (for 63 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)
6number of podocytes per kidney glomerulusCrl:SDmale212.59control condition100793control condition
5liver weight to body weight ratioCrl:SDmale0.46g/kgcontrol condition (for 63 days)105045control condition (for 63 days)
5both kidneys wet weight to body weight ratioCrl:SDmale0.097g/kgcontrol condition (for 63 days)105047control condition (for 63 days)
5serum aspartate aminotransferase activity levelCrl:SDmale61.8U/lcontrol condition (for 63 days)105049control condition (for 63 days)
5serum alanine aminotransferase activity levelCrl:SDmale54.8U/lcontrol condition (for 63 days)105051control condition (for 63 days)
5serum alkaline phosphatase activity levelCrl:SDmale294.2U/lcontrol condition (for 63 days)105053control condition (for 63 days)
5serum total bilirubin levelCrl:SDmale0.1mg/dlcontrol condition (for 63 days)105055control condition (for 63 days)
5serum urea nitrogen levelCrl:SDmale12.4mg/dlcontrol condition (for 63 days)105059control condition (for 63 days)
5serum creatinine levelCrl:SDmale0.23mg/dlcontrol condition (for 63 days)105061control condition (for 63 days)
5serum total cholesterol levelCrl:SDmale89.4mg/dlcontrol condition (for 63 days)105063control condition (for 63 days)
5serum glucose levelCrl:SDmale132.6mg/dlcontrol condition (for 63 days)105065control condition (for 63 days)
9urine total protein excretion rateCrl:SDmale54mg/dcontrolled protein content diet (20 %) 108595controlled protein content diet (20 %)
9urine total protein excretion rateCrl:SDmale57mg/dcontrolled protein content diet (20 %) then water (for 120 days)108596controlled protein content diet (20 %) water (for 120 days)
9systolic blood pressureCrl:SDmale168mmHgcontrolled protein content diet (20 %) then water (for 120 days)108593controlled protein content diet (20 %) water (for 120 days)
8systolic blood pressureCrl:SDmale130mmHgcontrolled protein content diet (20 %) then perindopril (1 mg/kg/d) (for 120 days)108594controlled protein content diet (20 %) perindopril (1 mg/kg/d) (for 120 days)
8urine total protein excretion rateCrl:SDmale32mg/dcontrolled protein content diet (20 %) then perindopril (1 mg/kg/d) (for 120 days)108597controlled protein content diet (20 %) perindopril (1 mg/kg/d) (for 120 days)
8urine total protein excretion rateCrl:SDmale61mg/dcontrolled protein content diet (20 %) 108598controlled protein content diet (20 %)
11volume of blood removed to total prehemorrhagic blood volume ratioCrl:SDmale56.8%arterial catheter implantation (for 1 days) then controlled hemorrhage (between 1 and 6 hours)109134arterial catheter implantation (for 1 days)controlled hemorrhage (between 1 and 6 hours)
11water intake drink rate to body weight ratioCrl:SDmale0.49ml/d/kgarterial catheter implantation (for 1 days)107165arterial catheter implantation (for 1 days)
11hematocritCrl:SDmale40.9%arterial catheter implantation (for 1 days)107244arterial catheter implantation (for 1 days)
11hematocritCrl:SDmale29.8%arterial catheter implantation (for 1 days) then controlled hemorrhage (between 1 and 6 hours)107260arterial catheter implantation (for 1 days)controlled hemorrhage (between 1 and 6 hours)
11absolute change in hematocritCrl:SDmale11.1%arterial catheter implantation (for 1 days) then controlled hemorrhage (between 1 and 6 hours)107276arterial catheter implantation (for 1 days)controlled hemorrhage (between 1 and 6 hours)
11mean arterial blood pressureCrl:SDmale115mmHgarterial catheter implantation (for 1 days)107340arterial catheter implantation (for 1 days)
11body weightCrl:SDmale448gcontrol condition107351control condition
11maximum body weight loss to initial body weight ratioCrl:SDmale3.3%arterial catheter implantation (for 1 days)107186arterial catheter implantation (for 1 days)
11food intake weight to body weight ratioCrl:SDmale5.5g/d/100garterial catheter implantation (for 1 days)107149arterial catheter implantation (for 1 days)
N/Aplasma globulin levelCrl:SDmale31.16g/lcontrol condition106835control condition
N/Aplasma globulin levelCrl:SDfemale31.8g/lcontrol condition106836control condition
N/Aplasma urea nitrogen levelCrl:SDmale6.01mmol/lcontrol condition106839control condition
N/Aplasma urea nitrogen levelCrl:SDfemale5.21mmol/lcontrol condition106840control condition
N/Aplasma triglyceride levelCrl:SDmale0.83mmol/lcontrol condition106843control condition
N/Aplasma triglyceride levelCrl:SDfemale0.77mmol/lcontrol condition106844control condition
N/Aplasma total cholesterol levelCrl:SDmale66.7953mg/dlcontrol condition106847control condition
N/Aplasma total cholesterol levelCrl:SDfemale71.0424mg/dlcontrol condition106848control condition
N/Aplasma sodium levelCrl:SDmale139.6mmol/lcontrol condition106851control condition
N/Aplasma sodium levelCrl:SDfemale141.8mmol/lcontrol condition106852control condition
N/Aplasma potassium levelCrl:SDmale4.33mmol/lcontrol condition106855control condition
N/Aplasma potassium levelCrl:SDfemale3.74mmol/lcontrol condition106856control condition
N/Aplasma glucose levelCrl:SDmale180mg/dlcontrol condition106859control condition
N/Aplasma glucose levelCrl:SDfemale160.02mg/dlcontrol condition106860control condition
N/Aplasma gamma-glutamyltransferase activity levelCrl:SDmale0.6U/lcontrol condition106863control condition
N/Aplasma gamma-glutamyltransferase activity levelCrl:SDfemale0U/lcontrol condition106864control condition
N/Aplasma creatinine levelCrl:SDmale0.166628706mg/dlcontrol condition106867control condition
N/Aplasma creatinine levelCrl:SDfemale0.198868476mg/dlcontrol condition106868control condition
N/Aplasma chloride levelCrl:SDmale101.83mmol/lcontrol condition106871control condition
N/Aplasma chloride levelCrl:SDfemale101.6mmol/lcontrol condition106872control condition
N/Aplasma alkaline phosphatase activity levelCrl:SDmale279.8IU/lcontrol condition106875control condition
N/Aplasma alkaline phosphatase activity levelCrl:SDfemale160.4IU/lcontrol condition106876control condition
N/Aplasma alanine aminotransferase activity levelCrl:SDmale51.16U/lcontrol condition106879control condition
N/Aplasma alanine aminotransferase activity levelCrl:SDfemale41U/lcontrol condition106880control condition
N/Aplasma albumin levelCrl:SDmale25.8g/lcontrol condition106831control condition
N/Aplasma albumin levelCrl:SDfemale28.2g/lcontrol condition106832control condition
N/Aplasma osmolalityCrl:SDfemale284.8umol/gcontrol condition111471control condition
N/Aplasma phosphate levelCrl:SDmale7.33464mg/dlcontrol condition110144control condition
N/Aplasma phosphate levelCrl:SDfemale6.17232mg/dlcontrol condition110145control condition
N/Aplasma calcium levelCrl:SDmale2.38mmol/lcontrol condition110148control condition
N/Aplasma calcium levelCrl:SDfemale2.38mmol/lcontrol condition110149control condition
N/Aplasma total bilirubin levelCrl:SDmale0.13224mg/dlcontrol condition111466control condition
N/Aplasma total bilirubin levelCrl:SDfemale0.13862mg/dlcontrol condition111467control condition
N/Aplasma osmolalityCrl:SDmale284.6umol/gcontrol condition111470control condition