SD |
blood sodium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
female |
71 days-85 days |
6 |
|
|
150.33 |
mmol/l |
0.76 |
1.86 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85128 |
1602 |
SD |
blood calcium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
female |
85 days-99 days |
6 |
|
|
10.08 |
mg/dl |
0.1 |
0.25 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85154 |
1602 |
SD |
blood total cholesterol level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
male |
71 days-85 days |
6 |
|
|
86.8 |
mg/dl |
5.76 |
14.12 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85170 |
1602 |
SD |
liver wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
85 days-99 days |
6 |
|
|
3.69 |
g |
0.16 |
0.38 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85204 |
1602 |
SD |
both kidneys wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
85 days-99 days |
6 |
|
|
0.76 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85210 |
1602 |
SD |
spleen wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
71 days-85 days |
6 |
|
|
0.2 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85244 |
1602 |
SD |
spleen wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
85 days-99 days |
6 |
|
|
0.23 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85253 |
1602 |
SD |
brain wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
71 days-85 days |
6 |
|
|
0.72 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85255 |
1602 |
SD |
brain wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
71 days-85 days |
6 |
|
|
0.74 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85256 |
1602 |
SD |
brain wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
85 days-99 days |
6 |
|
|
1.09 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85264 |
1602 |
SD |
adrenal gland wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
71 days-85 days |
6 |
|
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85267 |
1602 |
SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
71 days-85 days |
6 |
|
|
0.04 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85272 |
1602 |
SD |
uterus wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
71 days-85 days |
6 |
|
|
0.35 |
g |
0.06 |
0.15 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85284 |
1602 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
50 days-64 days |
6 |
|
|
211.0 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84766 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
70 days-84 days |
6 |
|
|
262.4 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84779 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
64 days-78 days |
6 |
|
|
246.1 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84786 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
70 days-84 days |
6 |
|
|
255.5 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84788 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
50 days-64 days |
6 |
|
|
208.8 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84790 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
64 days-78 days |
6 |
|
|
252.7 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84792 |
1602 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
57 days-71 days |
6 |
|
|
161.2 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84801 |
1602 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
64 days-78 days |
6 |
|
|
170.0 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84802 |
1602 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 1 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
42 days-56 days |
6 |
|
|
134.7 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84804 |
1602 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
50 days-64 days |
6 |
|
|
147.9 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84805 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 1 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
42 days-56 days |
6 |
|
|
134.2 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84809 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
42 days-56 days |
6 |
|
|
137.3 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84814 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
57 days-71 days |
6 |
|
|
153.9 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84821 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
64 days-78 days |
6 |
|
|
160.7 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84822 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50 days-64 days |
6 |
|
|
33.1 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84824 |
1602 |
SD |
food intake rate |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70 days-84 days |
6 |
|
|
31.7 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84835 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50 days-64 days |
6 |
|
|
34.9 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84836 |
1602 |
SD |
red blood cell count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71 days-85 days |
6 |
|
|
8.47 |
x 10E6 cells/ul |
0.19 |
0.47 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84896 |
1602 |
SD |
blood glucose level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
male |
85 days-99 days |
6 |
|
|
72.48 |
mg/dl |
12.78 |
31.31 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84991 |
1602 |
SD |
blood urea nitrogen level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
female |
85 days-99 days |
6 |
|
|
21.0 |
mg/dl |
0.63 |
1.55 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85046 |
1602 |
SD |
blood creatinine level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
female |
71 days-85 days |
6 |
|
|
0.4 |
mg/dl |
0.0 |
0.0 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85066 |
1602 |
SD |
blood alanine aminotransferase activity level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
male |
71 days-85 days |
6 |
|
|
59.8 |
U/l |
2.44 |
5.98 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85085 |
1602 |
SD |
blood alanine aminotransferase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
male |
85 days-99 days |
6 |
|
|
39.74 |
U/l |
8.84 |
21.66 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85088 |
1602 |
SD |
blood alanine aminotransferase activity level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
female |
71 days-85 days |
6 |
|
|
59.67 |
U/l |
3.76 |
9.22 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85091 |
1602 |
SD |
blood bilirubin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
male |
85 days-99 days |
6 |
|
|
0.52 |
mg/dl |
0.09 |
0.22 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85111 |
1602 |
SD |
blood potassium level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
male |
71 days-85 days |
6 |
|
|
5.0 |
mmol/l |
0.2 |
0.48 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85132 |
1602 |
SD |
blood phosphate level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
female |
85 days-99 days |
6 |
|
|
5.5 |
mg/dl |
0.15 |
0.37 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85166 |
1602 |
SD |
blood calcium level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
male |
71 days-85 days |
6 |
|
|
10.2 |
mg/dl |
0.1 |
0.24 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85145 |
1602 |
SD |
blood calcium level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
female |
71 days-85 days |
6 |
|
|
10.0 |
mg/dl |
0.04 |
0.09 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85151 |
1602 |
SD |
blood triglyceride level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
male |
85 days-99 days |
6 |
|
|
58.81 |
mg/dl |
10.11 |
24.76 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85184 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57 days-71 days |
6 |
|
|
34.5 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84841 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64 days-78 days |
6 |
|
|
33.7 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84842 |
1602 |
SD |
blood globulin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
male |
71 days-85 days |
6 |
|
|
3.0 |
g/dl |
0.02 |
0.05 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85026 |
1602 |
SD |
blood globulin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
female |
85 days-99 days |
6 |
|
|
3.08 |
g/dl |
0.04 |
0.11 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85034 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 1 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
42 days-56 days |
6 |
|
|
139.0 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84819 |
1602 |
SD |
food intake rate |
acetaminophen (250 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57 days-71 days |
6 |
|
|
34.3 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84829 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70 days-84 days |
6 |
|
|
25.7 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84863 |
1602 |
SD |
red blood cell count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71 days-85 days |
6 |
|
|
8.93 |
x 10E6 cells/ul |
0.23 |
0.56 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84911 |
1602 |
SD |
hematocrit |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71 days-85 days |
6 |
|
|
44.38 |
% |
0.79 |
1.94 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84952 |
1602 |
SD |
hematocrit |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71 days-85 days |
6 |
|
|
41.03 |
% |
1.15 |
2.81 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84957 |
1602 |
SD |
testis wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
71 days-85 days |
6 |
|
|
1.03 |
g |
0.15 |
0.37 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85281 |
1602 |
SD |
uterus wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
71 days-85 days |
6 |
|
|
0.28 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85285 |
1602 |
SD |
uterus wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
71 days-85 days |
6 |
|
|
0.45 |
g |
0.05 |
0.12 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85286 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50 days-64 days |
6 |
|
|
22.4 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84848 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64 days-78 days |
6 |
|
|
24.5 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84850 |
1602 |
SD |
both kidneys wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
71 days-85 days |
6 |
|
|
0.85 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85213 |
1602 |
SD |
both kidneys wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
85 days-99 days |
6 |
|
|
0.87 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85216 |
1602 |
SD |
both lungs wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
71 days-85 days |
6 |
|
|
0.72 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85219 |
1602 |
SD |
both lungs wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
71 days-85 days |
6 |
|
|
0.73 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85227 |
1602 |
SD |
both lungs wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
85 days-99 days |
6 |
|
|
0.79 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85228 |
1602 |
SD |
blood hemoglobin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
85 days-99 days |
6 |
|
|
11.02 |
g/dl |
0.23 |
0.57 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84949 |
1602 |
SD |
platelet count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
71 days-85 days |
6 |
|
|
1095.83 |
x 1000 cells/ul |
79.61 |
195.01 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84975 |
1602 |
SD |
platelet count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
71 days-85 days |
6 |
|
|
1263.0 |
x 1000 cells/ul |
34.55 |
84.62 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84978 |
1602 |
SD |
blood glucose level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
male |
71 days-85 days |
6 |
|
|
103.7 |
mg/dl |
5.52 |
13.52 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84988 |
1602 |
SD |
blood albumin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
85 days-99 days |
6 |
|
|
2.93 |
g/dl |
0.55 |
1.35 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85003 |
1602 |
SD |
blood albumin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
71 days-85 days |
6 |
|
|
3.5 |
g/dl |
0.06 |
0.14 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85005 |
1602 |
SD |
blood albumin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
71 days-85 days |
6 |
|
|
3.5 |
g/dl |
0.14 |
0.35 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85006 |
1602 |
SD |
blood albumin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
71 days-85 days |
6 |
|
|
4.6 |
g/dl |
0.38 |
0.92 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85008 |
1602 |
SD |
plasma total protein level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
male |
71 days-85 days |
6 |
|
|
63.0 |
mg/ml |
0.82 |
2.0 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85011 |
1602 |
SD |
liver wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
85 days-99 days |
6 |
|
|
3.18 |
g |
0.13 |
0.31 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85195 |
1602 |
SD |
blood glucose level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
male |
71 days-85 days |
6 |
|
|
115.3 |
mg/dl |
5.86 |
14.35 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84987 |
1602 |
SD |
blood albumin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
71 days-85 days |
6 |
|
|
3.3 |
g/dl |
0.05 |
0.13 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84999 |
1602 |
SD |
blood albumin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
71 days-85 days |
6 |
|
|
3.2 |
g/dl |
0.09 |
0.22 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85001 |
1602 |
SD |
heart rate |
artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
436.0 |
beats/min |
18.0 |
44.09 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
360 |
min |
|
|
|
98793 |
2160 |
SD |
heart rate |
sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
365.0 |
beats/min |
15.0 |
36.74 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
5 |
days |
|
|
|
98800 |
2160 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
70.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
720 |
min |
|
|
|
98808 |
2160 |
SD |
body weight |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) and enalapril (25 mg/l) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
body mass |
female |
0 days
| 12 |
|
|
290.6 |
g |
6.8 |
23.56 |
body weighing method |
0.0 |
unx |
97 |
days |
|
|
|
100635 |
2499 |
SD |
serum creatinine level |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then vehicle control condition (100 ul) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood creatinine amount |
female |
0 days
| 13 |
|
|
1.65 |
mg/dl |
0.14 |
0.5 |
serum creatinine analysis |
0.0 |
unx |
97 |
days |
|
|
|
100637 |
2499 |
SD |
creatinine clearance |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then enalapril (25 mg/l) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
glomerular filtration trait |
female |
0 days
| 12 |
|
|
0.56 |
ml/min |
0.03 |
0.1 |
serum creatinine analysis |
0.0 |
unx |
97 |
days |
|
|
|
100643 |
2499 |
SD |
serum parathyroid hormone level |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then vehicle control condition (100 ul) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood parathyroid hormone amount |
female |
0 days
| 13 |
|
|
3496.0 |
pg/ml |
862.0 |
3107.99 |
serum parathyroid hormone analysis |
0.0 |
unx |
97 |
days |
|
|
|
100647 |
2499 |
SD |
serum parathyroid hormone level |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then enalapril (25 mg/l) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood parathyroid hormone amount |
female |
0 days
| 12 |
|
|
371.0 |
pg/ml |
100.0 |
346.41 |
serum parathyroid hormone analysis |
0.0 |
unx |
97 |
days |
|
|
|
100648 |
2499 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
5.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
720 |
min |
|
|
|
98820 |
2160 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
8.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98828 |
2160 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
5.2 |
null |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
720 |
min |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
98868 |
2160 |
SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.8 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
2 |
days |
|
|
|
98876 |
2160 |
SD |
ejection fraction |
sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
cardiac output trait |
male |
0 days
| 6 |
|
|
64.0 |
% |
3.0 |
7.35 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
5 |
days |
|
|
|
98885 |
2160 |
SD |
left kidney wet weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 5 |
|
|
1.49 |
g |
0.1 |
0.23 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
|
remnant kidney |
|
101546 |
2602 |
SD |
systolic blood pressure |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 6 |
undefined |
|
118.0 |
mmHg |
3.67 |
9.0 |
tail cuff plethysmography |
0.0 |
sham unx |
13 |
days |
|
|
|
101547 |
2602 |
SD |
systolic blood pressure |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 5 |
undefined |
|
149.0 |
mmHg |
9.39 |
21.0 |
tail cuff plethysmography |
0.0 |
unx |
13 |
days |
|
|
|
101550 |
2602 |
SD |
body weight |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 8 |
|
|
300.0 |
g |
10.96 |
31.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
|
|
101608 |
2602 |
SD |
urine protein excretion rate |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
total urine protein amount |
male |
90 days
| 9 |
|
|
5.0 |
mg/d |
1.0 |
3.0 |
urine protein analysis |
0.0 |
|
0 |
|
|
|
|
101234 |
2582 |
SD |
serum creatinine level |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
blood creatinine amount |
male |
0 days
| 7 |
|
|
2.3 |
mg/dl |
0.5 |
1.32 |
automated serum creatinine analysis |
0.0 |
unx |
70 |
days |
|
|
|
98991 |
2179 |
SD |
serum creatinine level |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
blood creatinine amount |
male |
0 days
| 7 |
|
|
0.8 |
mg/dl |
0.1 |
0.26 |
automated serum creatinine analysis |
0.0 |
unx |
70 |
days |
|
|
|
98993 |
2179 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 6 |
|
|
1.9 |
% |
0.49 |
1.2 |
ex vivo light microscopy with histochemistry |
0.0 |
sham unx |
28 |
days |
|
|
|
101603 |
2602 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
7.2 |
mm |
0.3 |
0.73 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
360 |
min |
|
|
|
98843 |
2160 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
7.9 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
5 |
days |
|
|
|
98848 |
2160 |
SD |
heart left ventricle end-diastolic posterior wall thickness |
artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle posterior wall thickness |
male |
0 days
| 6 |
|
|
1.4 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
720 |
min |
|
|
|
98860 |
2160 |
SD |
heart left ventricle end-diastolic posterior wall thickness |
sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle posterior wall thickness |
male |
0 days
| 6 |
|
|
1.6 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
720 |
min |
|
|
|
98861 |
2160 |
SD |
heart left ventricle end-diastolic posterior wall thickness |
sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle posterior wall thickness |
male |
0 days
| 6 |
|
|
1.6 |
mm |
0.1 |
0.24 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
5 |
days |
|
|
|
98865 |
2160 |
SD |
maximum rate of positive change in left ventricular blood pressure |
sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
7985.0 |
mmHg/s |
200.0 |
489.9 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98889 |
2160 |
SD |
maximum rate of negative change in left ventricular blood pressure |
artificial aortocaval fistula (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
-5661.0 |
mmHg/s |
312.0 |
764.24 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98892 |
2160 |
SD |
body weight |
left nephrectomy then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 7 |
|
|
257.0 |
g |
4.0 |
10.58 |
body weighing method |
0.0 |
unx |
0 |
|
|
|
|
98926 |
2179 |
SD |
body weight |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 9 |
|
|
308.0 |
g |
10.0 |
30.0 |
body weighing method |
0.0 |
unx |
56 |
days |
|
|
|
98933 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 9 |
|
|
148.0 |
mmHg |
4.0 |
12.0 |
tail cuff plethysmography |
0.0 |
unx |
28 |
days |
|
|
|
98942 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 9 |
|
|
129.0 |
mmHg |
4.0 |
12.0 |
body weighing method |
0.0 |
unx |
70 |
days |
|
|
|
98948 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
97.0 |
mg/d |
4.0 |
10.58 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
56 |
days |
|
|
|
98958 |
2179 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 23 |
|
|
26.8 |
null |
2.46 |
11.8 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98219 |
2040 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 9 |
|
|
3.4 |
null |
0.3 |
0.9 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
28 |
days |
|
|
|
98966 |
2179 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 9 |
|
|
13.6 |
null |
3.3 |
9.9 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
70 |
days |
|
|
|
98972 |
2179 |
SD |
body weight |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
body mass |
male |
0 days
| 8 |
|
|
563.0 |
g |
12.37 |
35.0 |
body weighing method |
0.0 |
stz |
154 |
days |
|
|
|
99891 |
2358 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 16 |
|
|
38.2 |
s |
3.53 |
14.1 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
1 |
days |
|
time to platform |
|
98241 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 16 |
|
|
14.9 |
s |
1.78 |
7.1 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
3 |
days |
|
time to platform |
|
98243 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 10 |
|
|
36.0 |
s |
3.76 |
11.9 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
1 |
days |
|
time in platform |
|
98244 |
2040 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 8 |
|
|
65.1 |
s |
12.59 |
35.6 |
elevated plus maze apparatus method |
300.0 |
sham coronal plane rotational acceleration of the head |
30 |
days |
|
time in open arms |
|
98257 |
2040 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 17 |
|
|
64.9 |
s |
10.67 |
44.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
time in open arms |
|
98258 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 8 |
|
|
18.9 |
s |
4.21 |
11.9 |
Morris water maze method |
60.0 |
sham coronal plane rotational acceleration of the head |
30 |
days |
|
time to platform |
|
98263 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 11 |
|
|
38.5 |
s |
3.95 |
13.1 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
29 |
days |
|
time to platform |
|
98268 |
2040 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
lvedd/pw |
|
4.6 |
null |
0.3 |
0.67 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
99357 |
2278 |
SD |
systolic blood pressure |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
arterial blood pressure trait |
male |
140 days
| 8 |
|
serial mean |
134.3 |
mmHg |
13.2 |
37.34 |
tail cuff plethysmography |
0.0 |
unx |
84 |
days |
|
|
|
100116 |
2419 |
SD |
heart weight to body weight ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
98 days
| 8 |
|
|
2.7 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
|
|
99199 |
2278 |
SD |
heart right ventricle weight to body weight ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart right ventricle mass |
male |
98 days
| 8 |
|
|
0.5 |
mg/g |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
|
|
99207 |
2278 |
SD |
heart rate |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
98 days
| 8 |
|
|
271.0 |
beats/min |
11.0 |
31.11 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99216 |
2278 |
SD |
heart rate |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
175 days
| 10 |
|
|
217.0 |
beats/min |
12.0 |
37.95 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
105 |
days |
|
|
|
99217 |
2278 |
SD |
heart rate |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
175 days
| 10 |
|
|
220.0 |
beats/min |
5.0 |
15.81 |
vascular transducer tipped catheter |
0.0 |
ACF |
105 |
days |
|
|
|
99218 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
8947.0 |
mmHg/s |
745.0 |
2107.18 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99228 |
2278 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 8 |
|
|
48.8 |
s |
2.83 |
8.0 |
Morris water maze method |
60.0 |
sham coronal plane rotational acceleration of the head |
1 |
days |
|
time to platform |
|
98228 |
2040 |
SD |
systolic blood pressure |
controlled enalapril content drinking water (5 mg/kg/d) (for 10 days) |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
130 days
| 1 |
mean of 3 samples - 1 per minute |
serial mean |
117.0 |
mmHg |
4.0 |
4.0 |
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100178 |
2439 |
SD |
creatinine clearance |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
glomerular filtration trait |
male |
60 days
| 3 |
|
|
0.0 |
ml/min |
0.0 |
0.0 |
urine creatinine analysis |
0.0 |
|
0 |
|
|
|
|
100210 |
2439 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 8 |
|
|
17.8 |
s |
3.75 |
10.6 |
Morris water maze method |
60.0 |
sham coronal plane rotational acceleration of the head |
2 |
days |
|
time to platform |
|
98229 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 8 |
|
|
21.2 |
s |
4.38 |
12.4 |
Morris water maze method |
60.0 |
sham coronal plane rotational acceleration of the head |
3 |
days |
|
time to platform |
|
98230 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 21 |
|
|
34.5 |
s |
2.44 |
11.2 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
1 |
days |
|
time to platform |
|
98235 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 21 |
|
|
21.2 |
s |
2.44 |
11.2 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
3 |
days |
|
time to platform |
|
98237 |
2040 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
lvedd/pw |
|
7.7 |
null |
0.5 |
1.41 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
heart left ventricle end-diastolic dimeter to posterior wall thickness ratio |
|
99244 |
2278 |
SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
|
|
40.0 |
% |
1.0 |
3.16 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
|
|
99257 |
2278 |
SD |
heart left ventricle interstitial norepinephrine level during a period of time |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial norepinephrine amount |
male |
98 days
| 8 |
|
|
6.2 |
pg/hr |
1.0 |
2.83 |
enzyme linked immunosorbent assay |
0.0 |
sham ACF |
28 |
days |
|
heart left ventricle interstitial bradykinin level during a period of time |
|
99267 |
2278 |
SD |
heart left ventricle interstitial norepinephrine level during a period of time |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial norepinephrine amount |
male |
175 days
| 10 |
|
|
10.2 |
pg/hr |
1.0 |
3.16 |
enzyme linked immunosorbent assay |
0.0 |
ACF |
105 |
days |
|
heart left ventricle interstitial bradykinin level during a period of time |
|
99270 |
2278 |
SD |
plasma norepinephrine level |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood norepinephrine amount |
male |
98 days
| 8 |
|
|
93.0 |
pg/ml |
12.0 |
33.94 |
enzyme linked immunosorbent assay |
0.0 |
sham ACF |
28 |
days |
|
pl bk |
|
99283 |
2278 |
SD |
heart rate |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
72 days
| 5 |
|
|
359.0 |
beats/min |
6.0 |
13.42 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99291 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
4.2 |
mmHg |
0.0 |
0.0 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99311 |
2278 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
85.0 |
mmHg |
3.0 |
7.94 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99319 |
2278 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
70.0 |
mmHg |
3.0 |
8.49 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99322 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
8505.0 |
mmHg/s |
450.0 |
1190.59 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99327 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
8937.0 |
mmHg/s |
423.0 |
1196.42 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99330 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
-5948.0 |
mmHg/s |
131.0 |
370.52 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99338 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
|
|
7.6 |
mm |
0.1 |
0.26 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99345 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
lvedd/pw |
|
5.8 |
null |
0.2 |
0.45 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
99356 |
2278 |
SD |
heart weight to body weight ratio |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart mass |
male |
77 days
| 6 |
|
|
3.09 |
g/kg |
0.03 |
0.07 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101083 |
2564 |
SD |
heart left ventricle weight |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle mass |
male |
77 days
| 6 |
|
|
0.67 |
g |
0.01 |
0.02 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101091 |
2564 |
SD |
heart left atrium weight to body weight ratio |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left atrium mass |
male |
77 days
| 6 |
|
|
0.07 |
mg/g |
0.0 |
0.01 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
law/bw |
|
101112 |
2564 |
SD |
heart right atrium weight to body weight ratio |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right atrium mass |
male |
77 days
| 6 |
|
|
0.11 |
mg/g |
0.0 |
0.01 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
raw/bw |
|
101119 |
2564 |
SD |
heart right atrium weight to body weight ratio |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right atrium mass |
male |
77 days
| 6 |
|
|
0.1 |
mg/g |
0.0 |
0.01 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
raw/bw |
|
101120 |
2564 |
SD |
heart right atrium weight to body weight ratio |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right atrium mass |
male |
189 days
| 6 |
|
|
0.08 |
mg/g |
0.01 |
0.01 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
raw/bw |
|
101122 |
2564 |
SD |
heart septum weight |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart septum morphology trait |
male |
189 days
| 6 |
|
|
0.29 |
g |
0.02 |
0.05 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
septum |
|
101126 |
2564 |
SD |
systolic blood pressure |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
120 days
| 11 |
mean of 3 samples - 1 per minute |
serial mean |
133.0 |
mmHg |
1.81 |
6.0 |
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100172 |
2439 |
SD |
systolic blood pressure |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
180 days
| 3 |
mean of 3 samples - 1 per minute |
serial mean |
134.0 |
mmHg |
2.31 |
4.0 |
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100174 |
2439 |
SD |
ejection fraction |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
98 days
| 8 |
|
|
63.0 |
% |
2.0 |
5.66 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99376 |
2278 |
SD |
ejection fraction |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
98 days
| 8 |
|
|
71.0 |
% |
1.0 |
2.83 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99378 |
2278 |
SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
54.0 |
g/cm2 |
3.0 |
6.71 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99396 |
2278 |
SD |
ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial collagen amount |
male |
72 days
| 5 |
|
|
2.1 |
% |
0.1 |
0.22 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
ACF |
2 |
days |
|
|
|
99404 |
2278 |
SD |
ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial collagen amount |
male |
98 days
| 8 |
|
|
3.2 |
% |
0.1 |
0.28 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
ACF |
28 |
days |
|
|
|
99410 |
2278 |
SD |
body weight |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
body mass |
male |
0 days
| 8 |
|
|
738.0 |
g |
27.93 |
79.0 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
99916 |
2358 |
SD |
systolic blood pressure |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
150.0 |
mmHg |
1.41 |
4.0 |
tail cuff plethysmography |
0.0 |
stz |
224 |
days |
|
|
|
99923 |
2358 |
SD |
glomerular filtration rate to body weight ratio |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.65 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
stz |
224 |
days |
|
|
|
99927 |
2358 |
SD |
effective renal plasma flow |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney plasma flow trait |
male |
0 days
| 8 |
|
|
2.31 |
ml/min/100g |
0.08 |
0.22 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
stz |
224 |
days |
|
|
|
99929 |
2358 |
SD |
effective renal plasma flow |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney plasma flow trait |
male |
0 days
| 8 |
|
|
2.33 |
ml/min/100g |
0.07 |
0.2 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
99931 |
2358 |
SD |
serum immunoglobulin E level |
control condition |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood immunoglobulin E amount |
not specified |
0 days
| 8 |
|
|
0.1 |
ug/l |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105406 |
3015 |
SD |
retinal uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
180.0 |
% |
12.0 |
20.78 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106116 |
3028 |
SD |
retinal uptake index of digoxin |
tritiated digoxin (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
27.9 |
% |
5.7 |
9.87 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
digoxin uptake index |
|
106119 |
3028 |
SD |
retinal uptake index of verapamil |
tritiated verapamil (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
439.0 |
% |
57.0 |
98.73 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
verapamil uptake index |
|
106122 |
3028 |
SD |
aqueous humor uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and quinidine (10 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
11.7 |
% |
0.6 |
1.04 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106133 |
3028 |
SD |
aqueous humor uptake index of digoxin |
tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
17.5 |
% |
5.8 |
10.05 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106135 |
3028 |
SD |
brain uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and quinidine (10 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
18.2 |
% |
1.2 |
2.08 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106151 |
3028 |
SD |
verapamil equilibrated distribution volume in aqueous humor |
tritiated verapamil (10 uCi) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
0.07 |
ml/g |
0.0 |
0.0 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
|
|
106109 |
3028 |
SD |
aqueous humor uptake index of digoxin |
tritiated digoxin (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
9.48 |
% |
0.55 |
0.95 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
digoxin uptake index |
|
106137 |
3028 |
SD |
serum interleukin-9 level |
control condition |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood interleukin-9 amount |
not specified |
0 days
| 8 |
|
|
0.08 |
ug/l |
0.0 |
0.01 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105414 |
3015 |
SD |
nifedipine mean residence time |
nifedipine (200 ug/kg) |
Lu J, et al., Sci Rep. 2017 Feb 20;7:42922. doi: 10.1038/srep42922. |
xenobiotic pharmacokinetics trait |
both |
56 days
| 6 |
|
|
38.06 |
min |
5.41 |
13.25 |
liquid chromatography-mass spectrometry |
0.0 |
|
0 |
|
2 hour tail vein blood sampling |
mrt nifidepine |
|
105718 |
3020 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 1 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
42 days-56 days |
6 |
|
|
182.3 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84765 |
1602 |
SD |
food intake rate |
acetaminophen (250 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50 days-64 days |
6 |
|
|
21.3 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84852 |
1602 |
SD |
food intake rate |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70 days-84 days |
6 |
|
|
26.0 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84855 |
1602 |
SD |
red blood cell count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71 days-85 days |
6 |
|
|
8.56 |
x 10E6 cells/ul |
0.2 |
0.49 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84895 |
1602 |
SD |
plasma total protein level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
female |
71 days-85 days |
6 |
|
|
65.0 |
mg/ml |
0.49 |
1.2 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85017 |
1602 |
SD |
blood urea nitrogen level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
female |
85 days-99 days |
6 |
|
|
16.0 |
mg/dl |
0.89 |
2.19 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85045 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
71 days-85 days |
6 |
|
|
0.9 |
null |
0.03 |
0.07 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85048 |
1602 |
SD |
blood creatinine level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
male |
71 days-85 days |
6 |
|
|
0.4 |
mg/dl |
0.03 |
0.08 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85062 |
1602 |
SD |
blood aspartate aminotransferase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
female |
85 days-99 days |
6 |
|
|
155.67 |
U/l |
3.85 |
9.42 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85081 |
1602 |
SD |
both kidneys wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
85 days-99 days |
6 |
|
|
0.84 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85211 |
1602 |
SD |
adrenal gland wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
71 days-85 days |
6 |
|
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85268 |
1602 |
SD |
blood differential white blood cell count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
71 days-85 days |
6 |
|
|
11.3 |
x 1000 cells/ul |
1.47 |
3.6 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84887 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
71 days-85 days |
6 |
|
|
11.87 |
% |
0.18 |
0.44 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84966 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
85 days-99 days |
6 |
|
|
11.35 |
% |
0.16 |
0.38 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84974 |
1602 |
SD |
blood glucose level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
male |
71 days-85 days |
6 |
|
|
86.8 |
mg/dl |
4.51 |
11.05 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84990 |
1602 |
SD |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84 days
| 10 |
|
|
5.07 |
% |
0.23 |
0.72 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
105725 |
3021 |
SD |
blood calcium level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
male |
71 days-85 days |
6 |
|
|
10.0 |
mg/dl |
0.09 |
0.23 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85144 |
1602 |
SD |
blood potassium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
female |
71 days-85 days |
6 |
|
|
4.57 |
mmol/l |
0.08 |
0.19 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85137 |
1602 |
SD |
renal plasma flow to body weight ratio |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
kidney plasma flow trait |
male |
420 days-450 days |
9 |
|
|
1.0 |
ml/min/100g |
0.06 |
0.18 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
101231 |
2582 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.2 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
2 |
days |
|
|
|
98790 |
2160 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
72.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98814 |
2160 |
SD |
serum creatinine level |
control condition |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood creatinine amount |
female |
0 days
| 8 |
|
|
0.58 |
mg/dl |
0.03 |
0.08 |
serum creatinine analysis |
0.0 |
|
0 |
days |
|
|
|
100636 |
2499 |
SD |
serum creatinine level |
left nephrectomy (for 70 days) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
blood creatinine amount |
male |
0 days
| 5 |
|
|
0.3 |
mg/dl |
0.0 |
0.0 |
automated serum creatinine analysis |
0.0 |
unx |
70 |
days |
|
|
|
103796 |
2179 |
SD |
adrenal gland weight |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 6 |
|
|
51.0 |
mg |
1.63 |
4.0 |
post excision weight measurement |
0.0 |
sham unx |
13 |
days |
|
|
|
101559 |
2602 |
SD |
plasma renin activity level |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
renin activity |
male |
0 days
| 6 |
|
|
3.1 |
ng/ml/h |
0.29 |
0.7 |
radioimmunoassay |
0.0 |
sham unx |
13 |
days |
|
|
|
101563 |
2602 |
SD |
body weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 8 |
|
|
315.0 |
g |
9.55 |
27.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
|
|
101607 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (for 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 8 |
|
|
201.0 |
mg/d |
31.47 |
89.0 |
urine protein analysis |
0.0 |
unx |
14 |
days |
|
|
|
101621 |
2602 |
SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 6 |
|
|
60.0 |
mg |
3.27 |
8.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101602 |
2602 |
SD |
red blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71 days-85 days |
6 |
|
|
8.26 |
x 10E6 cells/ul |
0.24 |
0.59 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84908 |
1602 |
SD |
body weight |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 7 |
|
|
301.0 |
g |
5.0 |
13.23 |
body weighing method |
0.0 |
unx |
28 |
days |
|
|
|
98929 |
2179 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
14.4 |
null |
2.2 |
5.82 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
70 |
days |
|
|
|
98971 |
2179 |
SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
|
|
1.9 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
stz |
154 |
days |
|
|
|
99894 |
2358 |
SD |
systolic blood pressure |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
127.0 |
mmHg |
1.06 |
3.0 |
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
99901 |
2358 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
50 days-64 days |
6 |
|
|
209.3 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84771 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50 days-64 days |
6 |
|
|
33.5 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84840 |
1602 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
5.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
360 |
min |
|
|
|
98819 |
2160 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
2.0 |
mmHg |
1.0 |
2.45 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
720 |
min |
|
|
|
98821 |
2160 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
71.0 |
mmHg |
5.0 |
12.25 |
vascular transducer tipped catheter |
1.0 |
ACF |
5 |
days |
|
|
|
98836 |
2160 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 8 |
|
|
24.1 |
s |
3.64 |
10.3 |
Morris water maze method |
60.0 |
sham coronal plane rotational acceleration of the head |
29 |
days |
|
time to platform |
|
98262 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 11 |
|
|
13.0 |
s |
1.54 |
5.1 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
time to platform |
|
98269 |
2040 |
SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
49.0 |
g/cm2 |
9.0 |
20.12 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
|
|
99397 |
2278 |
SD |
blood albumin level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood albumin amount |
male |
140 days
| 7 |
|
|
3.1 |
g/dl |
0.2 |
0.53 |
automated blood albumin analysis |
0.0 |
unx |
84 |
days |
|
|
|
100166 |
2419 |
SD |
plasma bradykinin level |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood bradykinin amount |
male |
175 days
| 10 |
|
|
29.0 |
pg/ml |
5.0 |
15.81 |
radioimmunoassay |
0.0 |
ACF |
105 |
days |
|
|
|
99282 |
2278 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
72 days
| 5 |
|
|
106.0 |
mmHg |
1.0 |
2.24 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99301 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
5.0 |
mmHg |
1.0 |
2.24 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99309 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
-7422.0 |
mmHg/s |
236.0 |
624.4 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99336 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
|
7.0 |
mm |
0.1 |
0.22 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
|
|
99341 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
|
10.6 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99344 |
2278 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
72 days
| 5 |
|
|
4.0 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
|
|
99347 |
2278 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
72 days
| 5 |
|
|
4.1 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
|
|
99349 |
2278 |
SD |
blood sodium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
male |
71 days-85 days |
6 |
|
|
143.8 |
mmol/l |
0.6 |
1.47 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85119 |
1602 |
SD |
blood sodium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
male |
85 days-99 days |
6 |
|
|
123.26 |
mmol/l |
24.32 |
59.56 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85123 |
1602 |
SD |
blood sodium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
female |
71 days-85 days |
6 |
|
|
146.5 |
mmol/l |
0.43 |
1.05 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85125 |
1602 |
SD |
blood sodium level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
female |
71 days-85 days |
6 |
|
|
146.67 |
mmol/l |
0.62 |
1.51 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85126 |
1602 |
SD |
blood sodium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
female |
85 days-99 days |
6 |
|
|
145.33 |
mmol/l |
0.92 |
2.25 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85130 |
1602 |
SD |
blood phosphate level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
male |
85 days-99 days |
6 |
|
|
4.06 |
mg/dl |
0.91 |
2.22 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85160 |
1602 |
SD |
blood total cholesterol level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
male |
85 days-99 days |
6 |
|
|
60.1 |
mg/dl |
12.24 |
29.99 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85172 |
1602 |
SD |
blood triglyceride level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
female |
71 days-85 days |
6 |
|
|
44.0 |
mg/dl |
12.59 |
30.84 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85187 |
1602 |
SD |
liver wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
71 days-85 days |
6 |
|
|
4.31 |
g |
0.1 |
0.24 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85193 |
1602 |
SD |
liver wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
85 days-99 days |
6 |
|
|
3.51 |
g |
0.13 |
0.31 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85205 |
1602 |
SD |
both kidneys wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
71 days-85 days |
6 |
|
|
0.88 |
g |
0.02 |
0.06 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85207 |
1602 |
SD |
both kidneys wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
71 days-85 days |
6 |
|
|
0.94 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85212 |
1602 |
SD |
heart wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
71 days-85 days |
6 |
|
|
0.41 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85237 |
1602 |
SD |
spleen wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
85 days-99 days |
6 |
|
|
0.21 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85247 |
1602 |
SD |
brain wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
85 days-99 days |
6 |
|
|
0.68 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85259 |
1602 |
SD |
brain wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
71 days-85 days |
6 |
|
|
1.03 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85261 |
1602 |
SD |
testis wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
85 days-99 days |
6 |
|
|
1.0 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85282 |
1602 |
SD |
red blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71 days-85 days |
6 |
|
|
8.31 |
x 10E6 cells/ul |
0.22 |
0.53 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84894 |
1602 |
SD |
plasma total protein level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
female |
85 days-99 days |
6 |
|
|
66.0 |
mg/ml |
0.57 |
1.4 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85021 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
71 days-85 days |
6 |
|
|
1.1 |
null |
0.03 |
0.08 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85055 |
1602 |
SD |
blood creatinine level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
male |
71 days-85 days |
6 |
|
|
0.4 |
mg/dl |
0.02 |
0.05 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85061 |
1602 |
SD |
blood creatinine level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
female |
85 days-99 days |
6 |
|
|
0.33 |
mg/dl |
0.02 |
0.05 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85069 |
1602 |
SD |
blood creatinine level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
female |
85 days-99 days |
6 |
|
|
0.33 |
mg/dl |
0.02 |
0.05 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85070 |
1602 |
SD |
blood aspartate aminotransferase activity level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
male |
71 days-85 days |
6 |
|
|
136.8 |
U/l |
11.03 |
27.01 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85072 |
1602 |
SD |
blood aspartate aminotransferase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
female |
71 days-85 days |
6 |
|
|
263.17 |
U/l |
34.35 |
84.13 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85080 |
1602 |
SD |
blood alanine aminotransferase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
male |
85 days-99 days |
6 |
|
|
46.73 |
U/l |
8.3 |
20.33 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85087 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 1 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
42 days-56 days |
6 |
|
|
190.7 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84789 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
70 days-84 days |
6 |
|
|
264.0 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84793 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
42 days-56 days |
6 |
|
|
136.2 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84794 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
57 days-71 days |
6 |
|
|
156.6 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84796 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
70 days-84 days |
6 |
|
|
172.8 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84798 |
1602 |
SD |
food intake rate |
acetaminophen (500 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50 days-64 days |
6 |
|
|
33.3 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84832 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57 days-71 days |
6 |
|
|
35.1 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84837 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70 days-84 days |
6 |
|
|
23.1 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84851 |
1602 |
SD |
food intake rate |
acetaminophen (500 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50 days-64 days |
6 |
|
|
19.9 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84856 |
1602 |
SD |
blood phosphate level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
female |
71 days-85 days |
6 |
|
|
5.98 |
mg/dl |
0.33 |
0.82 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85163 |
1602 |
SD |
blood total cholesterol level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
male |
71 days-85 days |
6 |
|
|
78.0 |
mg/dl |
2.9 |
7.1 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85167 |
1602 |
SD |
blood calcium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
male |
85 days-99 days |
6 |
|
|
7.03 |
mg/dl |
1.67 |
4.1 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85148 |
1602 |
SD |
blood calcium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
female |
71 days-85 days |
6 |
|
|
9.95 |
mg/dl |
0.08 |
0.19 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85149 |
1602 |
SD |
blood phosphate level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
male |
71 days-85 days |
6 |
|
|
5.9 |
mg/dl |
0.18 |
0.43 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85158 |
1602 |
SD |
blood globulin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
male |
85 days-99 days |
6 |
|
|
2.5 |
g/dl |
0.49 |
1.2 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85027 |
1602 |
SD |
blood globulin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
female |
71 days-85 days |
6 |
|
|
3.0 |
g/dl |
0.02 |
0.06 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85030 |
1602 |
SD |
blood globulin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
female |
85 days-99 days |
6 |
|
|
3.0 |
g/dl |
0.03 |
0.08 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85033 |
1602 |
SD |
blood aspartate aminotransferase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
male |
85 days-99 days |
6 |
|
|
125.07 |
U/l |
25.92 |
63.49 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85076 |
1602 |
SD |
blood alkaline phosphatase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
female |
71 days-85 days |
6 |
|
|
206.0 |
U/l |
27.48 |
67.31 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85101 |
1602 |
SD |
blood alkaline phosphatase activity level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
female |
71 days-85 days |
6 |
|
|
353.33 |
U/l |
79.96 |
195.86 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85102 |
1602 |
SD |
blood bilirubin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
male |
85 days-99 days |
6 |
|
|
0.55 |
mg/dl |
0.07 |
0.16 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85112 |
1602 |
SD |
blood bilirubin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
female |
71 days-85 days |
6 |
|
|
0.39 |
mg/dl |
0.05 |
0.12 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85115 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
50 days-64 days |
6 |
|
|
207.4 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84761 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
57 days-71 days |
6 |
|
|
150.9 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84811 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64 days-78 days |
6 |
|
|
35.8 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84826 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70 days-84 days |
6 |
|
|
31.9 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84827 |
1602 |
SD |
hematocrit |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71 days-85 days |
6 |
|
|
41.85 |
% |
0.63 |
1.55 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84960 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70 days-84 days |
6 |
|
|
33.6 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84847 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
70 days-84 days |
6 |
|
|
160.5 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84818 |
1602 |
SD |
food intake rate |
acetaminophen (250 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64 days-78 days |
6 |
|
|
34.2 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84830 |
1602 |
SD |
blood differential white blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
71 days-85 days |
6 |
|
|
6.56 |
x 1000 cells/ul |
0.4 |
0.97 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84885 |
1602 |
SD |
blood differential white blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
71 days-85 days |
6 |
|
|
7.58 |
x 1000 cells/ul |
0.55 |
1.34 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84890 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
71 days-85 days |
6 |
|
|
11.97 |
% |
0.09 |
0.23 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84965 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
85 days-99 days |
6 |
|
|
11.73 |
% |
0.18 |
0.44 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84968 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
71 days-85 days |
6 |
|
|
12.62 |
% |
0.32 |
0.79 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84971 |
1602 |
SD |
blood albumin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
85 days-99 days |
6 |
|
|
2.48 |
g/dl |
0.57 |
1.39 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85004 |
1602 |
SD |
blood triglyceride level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
male |
71 days-85 days |
6 |
|
|
109.5 |
mg/dl |
30.43 |
74.55 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85181 |
1602 |
SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.3 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
720 |
min |
|
|
|
98787 |
2160 |
SD |
heart rate |
sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
380.0 |
beats/min |
10.0 |
24.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
2 |
days |
|
|
|
98802 |
2160 |
SD |
glomerular filtration rate to body weight ratio |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.68 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
stz |
154 |
days |
|
|
|
99903 |
2358 |
SD |
effective renal plasma flow |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney plasma flow trait |
male |
0 days
| 8 |
|
|
2.28 |
ml/min/100g |
0.05 |
0.15 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
stz |
154 |
days |
|
|
|
99905 |
2358 |
SD |
percentage of study population developing anorectal malformation during a period of time |
in utero condition (for 7 days) and corn oil (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
anorectal integrity trait |
male |
1 days
| 0 |
|
|
0.0 |
% |
|
|
ex vivo light microscopy with histochemistry |
1.0 |
|
0 |
|
|
anorectal malformation incidence |
|
98734 |
2158 |
SD |
anogenital distance to cube root of body weight ratio |
in utero condition (for 7 days) and corn oil (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
perineum length |
male |
1 days
| 0 |
|
|
1.57 |
null |
|
0.15 |
body measuring method |
1.0 |
|
0 |
|
|
mm/g^1/3 |
|
98738 |
2158 |
SD |
blood urea nitrogen level |
controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood urea nitrogen amount |
male |
140 days
| 6 |
|
|
17.7 |
mg/dl |
1.3 |
3.18 |
blood urea nitrogen analysis |
0.0 |
x |
0 |
days |
|
|
|
100152 |
2419 |
SD |
blood albumin level |
controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood albumin amount |
male |
140 days
| 6 |
|
|
3.7 |
g/dl |
0.1 |
0.24 |
automated blood albumin analysis |
0.0 |
x |
0 |
days |
|
|
|
100160 |
2419 |
SD |
plasma angiotensin II level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood angiotensin II amount |
male |
120 days
| 3 |
|
|
50.0 |
pg/ml |
11.55 |
20.0 |
enzyme immunoassay |
0.0 |
|
0 |
|
|
|
|
100227 |
2439 |
SD |
serum creatinine level |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) and enalapril (25 mg/l) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood creatinine amount |
female |
0 days
| 12 |
|
|
0.93 |
mg/dl |
0.05 |
0.17 |
serum creatinine analysis |
0.0 |
unx |
97 |
days |
|
|
|
100640 |
2499 |
SD |
creatinine clearance |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then vehicle control condition (100 ul) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
glomerular filtration trait |
female |
0 days
| 13 |
|
|
0.3 |
ml/min |
0.03 |
0.11 |
serum creatinine analysis |
0.0 |
unx |
97 |
days |
|
|
|
100642 |
2499 |
SD |
creatinine clearance |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
glomerular filtration trait |
female |
0 days
| 10 |
|
|
0.35 |
ml/min |
0.02 |
0.06 |
serum creatinine analysis |
0.0 |
unx |
97 |
days |
|
|
|
100644 |
2499 |
SD |
duration of loss of righting reflex |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (140 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
balance trait |
female |
0 days
| 14 |
|
|
129.0 |
s |
18.44 |
69.0 |
visual assessment of in vivo video recording |
0.0 |
|
0 |
|
|
time to rigthing reflex post anesthesia |
|
98199 |
2040 |
SD |
duration of loss of righting reflex |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
balance trait |
female |
0 days
| 25 |
|
|
223.0 |
s |
12.8 |
64.0 |
visual assessment of in vivo video recording |
0.0 |
|
0 |
|
|
time to rigthing reflex post anesthesia |
|
98202 |
2040 |
SD |
duration of loss of righting reflex |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
balance trait |
female |
0 days
| 19 |
|
|
222.0 |
s |
9.18 |
40.0 |
visual assessment of in vivo video recording |
0.0 |
|
0 |
|
|
time to rigthing reflex post anesthesia |
|
98203 |
2040 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
7.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
360 |
min |
|
|
|
98818 |
2160 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
13.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98826 |
2160 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
5.1 |
null |
0.5 |
1.22 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
360 |
min |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
98866 |
2160 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
5.3 |
null |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
5 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
98872 |
2160 |
SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 2 days) then vehicle control condition (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.6 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
2 |
days |
|
|
|
98874 |
2160 |
SD |
hematocrit |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
erythrocyte quantity |
male |
90 days
| 9 |
|
|
46.0 |
% |
1.0 |
3.0 |
hematocrit analysis |
0.0 |
|
0 |
|
|
|
|
101220 |
2582 |
SD |
renal plasma flow |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
kidney plasma flow trait |
male |
420 days-450 days |
9 |
|
|
5.73 |
ml/min |
0.41 |
1.23 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
101229 |
2582 |
SD |
renal plasma flow to body weight ratio |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
kidney plasma flow trait |
male |
90 days
| 9 |
|
|
0.97 |
ml/min/100g |
0.05 |
0.15 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
101230 |
2582 |
SD |
urine sodium excretion rate |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
urine sodium amount |
male |
420 days-450 days |
9 |
|
|
0.9 |
mEq/d |
0.2 |
0.6 |
urine sodium analysis |
0.0 |
|
0 |
|
|
|
|
101237 |
2582 |
SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 8 |
|
|
73.0 |
mg |
2.83 |
8.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101628 |
2602 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 8 |
|
|
31.0 |
% |
5.66 |
16.0 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
|
|
101629 |
2602 |
SD |
adrenal gland weight |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 6 |
|
|
46.0 |
mg |
0.82 |
2.0 |
post excision weight measurement |
0.0 |
sham unx |
28 |
days |
|
|
|
101599 |
2602 |
SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 7 |
|
|
69.0 |
mg |
3.4 |
9.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101600 |
2602 |
SD |
left kidney wet weight |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 6 |
|
|
1.11 |
g |
0.02 |
0.06 |
post excision weight measurement |
0.0 |
sham unx |
13 |
days |
|
remnant kidney |
|
101543 |
2602 |
SD |
left kidney wet weight |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 11 |
|
|
1.37 |
g |
0.07 |
0.23 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
|
remnant kidney |
|
101544 |
2602 |
SD |
urine total protein excretion rate |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 6 |
|
|
10.0 |
mg/d |
0.82 |
2.0 |
urine protein analysis |
0.0 |
sham unx |
13 |
days |
|
|
|
101551 |
2602 |
SD |
plasma aldosterone level |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood aldosterone amount |
male |
0 days
| 5 |
|
|
487.0 |
pg/ml |
50.98 |
114.0 |
plasma aldosterone analysis |
0.0 |
unx |
13 |
days |
|
|
|
101558 |
2602 |
SD |
heart wet weight |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
0 days
| 6 |
|
|
1.03 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
sham unx |
28 |
days |
|
|
|
101587 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 7 |
|
|
203.0 |
mg/d |
38.93 |
103.0 |
urine protein analysis |
0.0 |
unx |
28 |
days |
|
|
|
101592 |
2602 |
SD |
urine total protein excretion rate |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
70.0 |
mg/d |
10.0 |
26.46 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
70 |
days |
|
|
|
98959 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 9 |
|
|
78.0 |
mg/d |
12.0 |
36.0 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
70 |
days |
|
|
|
98960 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
127.0 |
mg/d |
16.0 |
42.33 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
70 |
days |
|
|
|
98961 |
2179 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 9 |
|
|
0.1 |
null |
0.02 |
0.06 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
0 |
|
|
protein/creatinine |
|
98963 |
2179 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
0.1 |
null |
0.02 |
0.05 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
0 |
|
|
|
|
98964 |
2179 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
7.6 |
null |
0.5 |
1.32 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
56 |
days |
|
|
|
98968 |
2179 |
SD |
left kidney wet weight |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
|
|
1.66 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
99895 |
2358 |
SD |
body weight |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
body mass |
male |
420 days-450 days |
9 |
|
|
572.0 |
g |
14.4 |
43.2 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
101215 |
2582 |
SD |
left kidney wet weight |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
kidney mass |
male |
90 days
| 9 |
|
|
1.22 |
g |
0.05 |
0.15 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
101216 |
2582 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
7.8 |
mm |
0.4 |
0.98 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
720 |
min |
|
|
|
98844 |
2160 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-systolic diameter |
male |
0 days
| 6 |
|
|
4.2 |
mm |
0.3 |
0.73 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
360 |
min |
|
|
|
98851 |
2160 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-systolic diameter |
male |
0 days
| 6 |
|
|
4.1 |
mm |
0.4 |
0.98 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
720 |
min |
|
|
|
98852 |
2160 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-systolic diameter |
male |
0 days
| 6 |
|
|
4.1 |
mm |
0.3 |
0.73 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
2 |
days |
|
|
|
98854 |
2160 |
SD |
heart left ventricle end-diastolic posterior wall thickness |
artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle posterior wall thickness |
male |
0 days
| 6 |
|
|
1.4 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
360 |
min |
|
|
|
98858 |
2160 |
SD |
heart left ventricle end-diastolic posterior wall thickness |
sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle posterior wall thickness |
male |
0 days
| 6 |
|
|
1.6 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
360 |
min |
|
|
|
98859 |
2160 |
SD |
heart left ventricle end-diastolic posterior wall thickness |
artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle posterior wall thickness |
male |
0 days
| 6 |
|
|
1.3 |
mm |
0.1 |
0.24 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
2 |
days |
|
|
|
98862 |
2160 |
SD |
body weight |
left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 7 |
|
|
256.0 |
g |
3.0 |
7.94 |
body weighing method |
0.0 |
unx |
0 |
|
|
|
|
98928 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 9 |
|
|
113.0 |
mmHg |
5.0 |
15.0 |
tail cuff plethysmography |
0.0 |
unx |
0 |
|
|
|
|
98939 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 7 |
|
|
111.0 |
mmHg |
4.0 |
10.58 |
tail cuff plethysmography |
0.0 |
unx |
0 |
|
|
|
|
98940 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 7 |
|
|
137.0 |
mmHg |
10.0 |
26.46 |
tail cuff plethysmography |
0.0 |
unx |
70 |
days |
|
|
|
98947 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 9 |
|
|
24.0 |
mg/d |
2.0 |
6.0 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
28 |
days |
|
|
|
98954 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
78.0 |
mg/d |
5.0 |
13.23 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
56 |
days |
|
|
|
98956 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 9 |
|
|
74.0 |
mg/d |
8.0 |
24.0 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
56 |
days |
|
|
|
98957 |
2179 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 10 |
|
|
15.8 |
s |
3.38 |
10.7 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time in platform |
|
98245 |
2040 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 8 |
|
|
1317.0 |
cm |
257.03 |
727.0 |
elevated plus maze apparatus method |
300.0 |
sham coronal plane rotational acceleration of the head |
30 |
days |
|
- |
|
98247 |
2040 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 9 |
|
|
1101.0 |
cm |
204.0 |
612.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
|
|
98250 |
2040 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 9 |
|
|
777.0 |
cm |
90.0 |
270.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
|
|
98251 |
2040 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 8 |
|
|
29.3 |
null |
3.78 |
10.7 |
elevated plus maze apparatus method |
300.0 |
sham coronal plane rotational acceleration of the head |
30 |
days |
|
|
|
98252 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 11 |
|
|
10.1 |
s |
1.66 |
5.5 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
31 |
days |
|
time to platform |
|
98270 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 9 |
|
|
10.5 |
s |
1.13 |
3.4 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
31 |
days |
|
time in platform |
|
98276 |
2040 |
SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
0 days
| 6 |
g/g*103 |
|
3.9 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
2 |
days |
|
|
|
98781 |
2160 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 21 |
|
|
29.7 |
null |
1.94 |
8.9 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98218 |
2040 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (140 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 14 |
|
|
954.0 |
cm |
107.97 |
404.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98211 |
2040 |
SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
|
39.0 |
% |
1.0 |
2.83 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99369 |
2278 |
SD |
ejection fraction |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
72 days
| 5 |
|
|
79.0 |
% |
3.0 |
6.71 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99374 |
2278 |
SD |
blood glucose level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood glucose amount |
male |
140 days
| 8 |
|
|
137.7 |
mg/dl |
8.3 |
23.48 |
blood glucose analysis |
0.0 |
unx |
84 |
days |
|
|
|
100122 |
2419 |
SD |
blood hemoglobin A1c level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood hemoglobin amount |
male |
140 days
| 6 |
|
|
3.3 |
% |
0.1 |
0.24 |
blood hemoglobin analysis |
0.0 |
unx |
84 |
days |
|
|
|
100132 |
2419 |
SD |
creatinine clearance |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
glomerular filtration trait |
male |
140 days
| 6 |
|
|
2.3 |
ml/min |
0.3 |
0.73 |
urine creatinine analysis |
0.0 |
unx |
84 |
days |
|
|
|
100140 |
2419 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (140 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 14 |
|
|
18.0 |
s |
4.2 |
15.7 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
3 |
days |
|
time to platform |
|
98234 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 23 |
|
|
37.8 |
s |
2.61 |
12.5 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
1 |
days |
|
time to platform |
|
98238 |
2040 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 23 |
|
|
50.7 |
s |
4.82 |
23.1 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time in open arms |
|
98225 |
2040 |
SD |
body weight |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
body mass |
male |
98 days
| 8 |
|
|
354.0 |
g |
9.0 |
25.46 |
scale |
0.0 |
ACF |
28 |
days |
|
|
|
99192 |
2278 |
SD |
heart weight |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
175 days
| 10 |
|
|
1.26 |
g |
0.03 |
0.09 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
|
|
99197 |
2278 |
SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
98 days
| 8 |
|
|
4.4 |
g/kg |
0.2 |
0.57 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
|
|
99200 |
2278 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle mass |
male |
98 days
| 8 |
|
|
2.1 |
mg/g |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
|
|
99203 |
2278 |
SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle mass |
male |
175 days
| 10 |
|
|
3.1 |
mg/g |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
|
|
99206 |
2278 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
175 days
| 10 |
|
|
95.0 |
mmHg |
4.0 |
12.65 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
105 |
days |
|
|
|
99221 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
7.0 |
mmHg |
1.0 |
2.83 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99224 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
-7479.0 |
mmHg/s |
337.0 |
953.18 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99231 |
2278 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
175 days
| 10 |
|
|
5.6 |
mm |
0.1 |
0.32 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
|
|
99241 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
lvedd/pw |
|
4.8 |
null |
0.3 |
0.85 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
heart left ventricle end-diastolic dimeter to posterior wall thickness ratio |
|
99243 |
2278 |
SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
16.0 |
g/cm2 |
1.0 |
3.16 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
|
|
99250 |
2278 |
SD |
heart left ventricle interstitial angiotensin II level during a period of time |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial angiotensin II amount |
male |
98 days
| 9 |
|
|
3.0 |
pg/hr |
0.4 |
1.2 |
radioimmunoassay |
0.0 |
ACF |
28 |
days |
|
heart left ventricle interstitial angiotensin II level during a period of time |
|
99260 |
2278 |
SD |
heart left ventricle interstitial bradykinin level during a period of time |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial bradykinin amount |
male |
175 days
| 8 |
|
|
7.4 |
pg/hr |
1.4 |
3.96 |
radioimmunoassay |
0.0 |
sham ACF |
105 |
days |
|
heart left ventricle interstitial bradykinin level during a period of time |
|
99265 |
2278 |
SD |
heart left ventricle interstitial epinephrine level during a period of time |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial epinephrine amount |
male |
175 days
| 10 |
|
|
8.6 |
pg/hr |
1.1 |
3.48 |
enzyme linked immunosorbent assay |
0.0 |
ACF |
105 |
days |
|
heart left ventricle interstitial epinephrine level during a period of time |
|
99274 |
2278 |
SD |
plasma angiotensin II level |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood angiotensin II amount |
male |
98 days
| 8 |
|
|
29.0 |
pg/ml |
3.0 |
8.49 |
radioimmunoassay |
0.0 |
sham ACF |
28 |
days |
|
|
|
99275 |
2278 |
SD |
plasma angiotensin II level |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood angiotensin II amount |
male |
98 days
| 9 |
|
|
107.0 |
pg/ml |
7.0 |
21.0 |
radioimmunoassay |
0.0 |
ACF |
28 |
days |
|
|
|
99276 |
2278 |
SD |
plasma epinephrine level |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood epinephrine amount |
male |
98 days
| 8 |
|
|
83.0 |
pg/ml |
12.0 |
33.94 |
enzyme linked immunosorbent assay |
0.0 |
sham ACF |
28 |
days |
|
|
|
99287 |
2278 |
SD |
heart rate |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
98 days
| 7 |
|
|
321.0 |
beats/min |
7.0 |
18.52 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99295 |
2278 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
98 days
| 7 |
|
|
107.0 |
mmHg |
3.0 |
7.94 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99303 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
11.0 |
mmHg |
1.0 |
2.24 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99308 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
10.0 |
mmHg |
1.0 |
2.83 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99314 |
2278 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
57.0 |
mmHg |
4.0 |
8.94 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99318 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
9065.0 |
mmHg/s |
354.0 |
791.57 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99326 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
|
|
7.7 |
mm |
0.2 |
0.53 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99343 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
|
10.2 |
mm |
0.2 |
0.57 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99346 |
2278 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
72 days
| 5 |
|
|
4.0 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99350 |
2278 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 7 |
|
|
4.7 |
mm |
0.2 |
0.53 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99351 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
lvedd/pw |
|
6.0 |
null |
0.4 |
1.13 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
99362 |
2278 |
SD |
heart weight |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart mass |
male |
77 days
| 6 |
|
|
1.25 |
g |
0.02 |
0.05 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101079 |
2564 |
SD |
heart weight |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart mass |
male |
189 days
| 10 |
|
|
1.57 |
g |
0.06 |
0.19 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101081 |
2564 |
SD |
heart left ventricle weight to body weight ratio |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle mass |
male |
189 days
| 10 |
|
|
1.53 |
mg/g |
0.04 |
0.13 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101097 |
2564 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle mass |
male |
189 days
| 6 |
|
|
1.44 |
mg/g |
0.02 |
0.05 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101098 |
2564 |
SD |
heart right ventricle weight |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right ventricle mass |
male |
77 days
| 6 |
|
|
0.23 |
g |
0.01 |
0.02 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101100 |
2564 |
SD |
heart left atrium weight to body weight ratio |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left atrium mass |
male |
77 days
| 6 |
|
|
0.1 |
mg/g |
0.0 |
0.01 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
law/bw |
|
101111 |
2564 |
SD |
right atrium weight |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right atrium mass |
male |
189 days
| 10 |
|
|
0.05 |
g |
0.0 |
0.01 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101117 |
2564 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 21 |
|
|
75.6 |
s |
8.58 |
39.3 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time in open arms |
|
98224 |
2040 |
SD |
ejection fraction |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
98 days
| 7 |
|
|
66.0 |
% |
2.0 |
5.29 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99375 |
2278 |
SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
4.0 |
g/cm2 |
1.0 |
2.65 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99391 |
2278 |
SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
50.0 |
g/cm2 |
3.0 |
6.71 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
lves-ws |
|
99395 |
2278 |
SD |
renal filtration fraction |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.3 |
null |
0.01 |
0.03 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
stz |
154 |
days |
GFR by inulin method |
|
|
99911 |
2358 |
SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
|
|
2.18 |
g |
0.05 |
0.14 |
post excision weight measurement |
0.0 |
stz |
224 |
days |
|
|
|
99917 |
2358 |
SD |
blood glucose level |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
|
|
358.0 |
mg/dl |
20.86 |
59.0 |
blood glucose analysis |
0.0 |
stz |
224 |
days |
|
|
|
99920 |
2358 |
SD |
blood glucose level |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
|
|
350.0 |
mg/dl |
19.09 |
54.0 |
blood glucose analysis |
0.0 |
stz |
224 |
days |
|
|
|
99921 |
2358 |
SD |
systolic blood pressure |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
128.0 |
mmHg |
1.06 |
3.0 |
tail cuff plethysmography |
0.0 |
stz |
224 |
days |
|
|
|
99924 |
2358 |
SD |
glomerular filtration rate to body weight ratio |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.67 |
ml/min/100g |
0.03 |
0.08 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
stz |
224 |
days |
|
|
|
99926 |
2358 |
SD |
renal filtration fraction |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.29 |
null |
0.01 |
0.02 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
stz |
224 |
days |
GFR by inulin method |
|
|
99933 |
2358 |
SD |
systolic blood pressure |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
60 days
| 5 |
mean of 3 samples - 1 per minute |
serial mean |
123.0 |
mmHg |
2.68 |
6.0 |
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100168 |
2439 |
SD |
systolic blood pressure |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
120 days
| 1 |
mean of 3 samples - 1 per minute |
serial mean |
121.0 |
mmHg |
|
|
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100188 |
2439 |
SD |
creatinine clearance |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
glomerular filtration trait |
male |
120 days
| 3 |
|
|
0.0 |
ml/min |
0.0 |
0.0 |
urine creatinine analysis |
0.0 |
|
0 |
|
|
|
|
100212 |
2439 |
SD |
plasma angiotensin I level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood angiotensin I amount |
male |
120 days
| 3 |
|
|
180.0 |
pg/ml |
80.83 |
140.0 |
enzyme immunoassay |
0.0 |
|
0 |
|
|
|
|
100221 |
2439 |
SD |
retinal uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
212.0 |
% |
13.0 |
22.52 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106114 |
3028 |
SD |
retinal uptake index of verapamil |
tritiated verapamil (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
336.0 |
% |
7.0 |
12.12 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
verapamil uptake index |
|
106120 |
3028 |
SD |
aqueous humor uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
5.95 |
% |
0.38 |
0.66 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106132 |
3028 |
SD |
brain uptake index of digoxin |
tritiated digoxin (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
0.99 |
% |
0.35 |
0.61 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
digoxin uptake index |
|
106153 |
3028 |
SD |
brain uptake index of digoxin |
tritiated digoxin (10 uCi) (for 0 hours) and digoxin (0.01 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
1.18 |
% |
0.2 |
0.35 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
digoxin uptake index |
|
106154 |
3028 |
SD |
brain uptake index of verapamil |
tritiated verapamil (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
77.7 |
% |
7.2 |
12.47 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
verapamil uptake index |
|
106158 |
3028 |
SD |
the first 120min of plasma nifedipine level area under curve |
nifedipine (200 ug/kg) |
Lu J, et al., Sci Rep. 2017 Feb 20;7:42922. doi: 10.1038/srep42922. |
blood xenobiotic amount |
both |
56 days
| 6 |
|
|
26979.23 |
min x (ng/ml) |
1522.03 |
3728.2 |
liquid chromatography-mass spectrometry |
0.0 |
|
0 |
|
2 hour tail vein blood sampling |
min x ng/ml |
|
105710 |
3020 |
SD |
verapamil apparent influx permeability clearance in aqueous humor |
tritiated verapamil (10 uCi) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
0.0 |
ml/min/g |
0.0 |
0.0 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
ml/(min x g) |
|
106103 |
3028 |
SD |
plasma nifedipine clearance |
nifedipine (200 ug/kg) |
Lu J, et al., Sci Rep. 2017 Feb 20;7:42922. doi: 10.1038/srep42922. |
xenobiotic pharmacokinetics trait |
both |
56 days
| 6 |
|
|
6.67 |
ml/min/kg |
0.51 |
1.25 |
liquid chromatography-mass spectrometry |
0.0 |
|
0 |
|
2 hour tail vein blood sampling |
cl nifidepine |
|
105716 |
3020 |
SD |
serum interleukin-4 level |
control condition |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood interleukin-4 amount |
not specified |
0 days
| 8 |
|
|
0.04 |
ug/l |
0.0 |
0.01 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105410 |
3015 |
SD |
serum interleukin-4 level |
acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood interleukin-4 amount |
not specified |
0 days
| 12 |
|
|
0.05 |
ug/l |
0.0 |
0.01 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105412 |
3015 |
SD |
serum interleukin-4 level |
acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood interleukin-4 amount |
not specified |
0 days
| 12 |
|
|
0.15 |
ug/l |
0.01 |
0.02 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105413 |
3015 |
SD |
intestine trypsin level |
acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
intestine trypsin amount |
not specified |
0 days
| 12 |
|
|
0.11 |
ug/l |
0.0 |
0.01 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105420 |
3015 |
SD |
body weight |
doxorubicin (5 mg/kg) (between 6 and 7 days) |
Eisenberger U, etal., Ren Physiol Biochem. 1995 Mar-Apr;18(2):89-96. doi: 10.1159/000173904. |
body mass |
female |
96 days-121 days |
7 |
|
|
192.0 |
g |
2.65 |
7.0 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
110178 |
3166 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
42 days-56 days |
6 |
|
|
180.4 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84760 |
1602 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
64 days-78 days |
6 |
|
|
244.0 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84768 |
1602 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 1 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
42 days-56 days |
6 |
|
|
181.7 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84770 |
1602 |
SD |
food intake rate |
acetaminophen (500 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57 days-71 days |
6 |
|
|
21.6 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84857 |
1602 |
SD |
blood urea nitrogen level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
male |
71 days-85 days |
6 |
|
|
14.2 |
mg/dl |
0.31 |
0.75 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85037 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
85 days-99 days |
6 |
|
|
0.77 |
null |
0.15 |
0.36 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85051 |
1602 |
SD |
blood creatinine level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
male |
71 days-85 days |
6 |
|
|
0.5 |
mg/dl |
0.03 |
0.08 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85059 |
1602 |
SD |
blood aspartate aminotransferase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
male |
71 days-85 days |
6 |
|
|
169.7 |
U/l |
11.38 |
27.88 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85071 |
1602 |
SD |
blood aspartate aminotransferase activity level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
male |
71 days-85 days |
6 |
|
|
140.8 |
U/l |
8.19 |
20.06 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85073 |
1602 |
SD |
blood aspartate aminotransferase activity level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
female |
71 days-85 days |
6 |
|
|
118.67 |
U/l |
12.26 |
30.03 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85078 |
1602 |
SD |
blood alanine aminotransferase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
male |
71 days-85 days |
6 |
|
|
54.0 |
U/l |
2.2 |
5.4 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85086 |
1602 |
SD |
blood bilirubin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
male |
71 days-85 days |
6 |
|
|
0.41 |
mg/dl |
0.04 |
0.11 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85109 |
1602 |
SD |
blood phosphate level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
male |
71 days-85 days |
6 |
|
|
6.3 |
mg/dl |
0.07 |
0.18 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85155 |
1602 |
SD |
blood total cholesterol level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
male |
85 days-99 days |
6 |
|
|
73.99 |
mg/dl |
12.53 |
30.68 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85171 |
1602 |
SD |
blood total cholesterol level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
female |
71 days-85 days |
6 |
|
|
102.5 |
mg/dl |
1.84 |
4.51 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85173 |
1602 |
SD |
liver wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
71 days-85 days |
6 |
|
|
4.2 |
g |
0.12 |
0.3 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85202 |
1602 |
SD |
both kidneys wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
71 days-85 days |
6 |
|
|
0.89 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85206 |
1602 |
SD |
brain wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
71 days-85 days |
6 |
|
|
0.75 |
g |
0.02 |
0.06 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85257 |
1602 |
SD |
brain wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
71 days-85 days |
6 |
|
|
1.1 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85260 |
1602 |
SD |
adrenal gland wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
85 days-99 days |
6 |
|
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85271 |
1602 |
SD |
uterus wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
71 days-85 days |
6 |
|
|
0.38 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85287 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
71 days-85 days |
6 |
|
|
10.98 |
% |
0.32 |
0.78 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84969 |
1602 |
SD |
platelet count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
85 days-99 days |
6 |
|
|
1122.17 |
x 1000 cells/ul |
129.6 |
317.45 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84980 |
1602 |
SD |
platelet count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
85 days-99 days |
6 |
|
|
846.0 |
x 1000 cells/ul |
35.44 |
86.81 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84985 |
1602 |
SD |
blood potassium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
female |
85 days-99 days |
6 |
|
|
4.77 |
mmol/l |
0.06 |
0.14 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85142 |
1602 |
SD |
blood triglyceride level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
female |
71 days-85 days |
6 |
|
|
22.8 |
mg/dl |
2.33 |
5.71 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85185 |
1602 |
SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
81.0 |
g/cm2 |
8.0 |
22.63 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99400 |
2278 |
SD |
heart rate |
sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
385.0 |
beats/min |
11.0 |
26.94 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
360 |
min |
|
|
|
98794 |
2160 |
SD |
heart rate |
artificial aortocaval fistula (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
420.0 |
beats/min |
14.0 |
34.29 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
2 |
days |
|
|
|
98801 |
2160 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
71.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98810 |
2160 |
SD |
verapamil equilibrated distribution volume in retina |
tritiated verapamil (10 uCi) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
3.32 |
ml/g |
0.2 |
0.34 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
|
|
106108 |
3028 |
SD |
aqueous humor uptake index of verapamil |
tritiated verapamil (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
8.46 |
% |
0.61 |
1.06 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
verapamil uptake index |
|
106138 |
3028 |
SD |
blood calcium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
male |
85 days-99 days |
6 |
|
|
8.27 |
mg/dl |
1.63 |
4.0 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85147 |
1602 |
SD |
blood calcium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
female |
71 days-85 days |
6 |
|
|
10.42 |
mg/dl |
0.13 |
0.31 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85152 |
1602 |
SD |
body weight |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then enalapril (25 mg/l) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
body mass |
female |
0 days
| 12 |
|
|
281.9 |
g |
4.2 |
14.55 |
body weighing method |
0.0 |
unx |
97 |
days |
|
|
|
100633 |
2499 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
2.0 |
mmHg |
1.0 |
2.45 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98823 |
2160 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
61.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
720 |
min |
|
|
|
98832 |
2160 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
56.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98834 |
2160 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
57.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98840 |
2160 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.5 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
2 |
days |
|
|
|
98877 |
2160 |
SD |
body weight |
sham surgical control condition (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
body mass |
male |
0 days
| 6 |
|
|
282.0 |
g |
16.0 |
39.19 |
body weighing method |
1.0 |
sham ACF |
2 |
days |
|
|
|
98774 |
2160 |
SD |
body weight |
sham surgical control condition (between 120 and 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
body mass |
male |
0 days
| 6 |
|
|
284.0 |
g |
4.0 |
9.8 |
body weighing method |
1.0 |
sham ACF |
5 |
days |
|
|
|
98776 |
2160 |
SD |
heart weight to body weight ratio |
sham surgical control condition (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
0 days
| 6 |
g/g*103 |
|
3.4 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
720 |
min |
|
|
|
98780 |
2160 |
SD |
maximum rate of positive change in left ventricular blood pressure |
artificial aortocaval fistula (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
6971.0 |
mmHg/s |
438.0 |
1072.88 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98888 |
2160 |
SD |
systolic blood pressure |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 5 |
undefined |
|
125.0 |
mmHg |
6.26 |
14.0 |
tail cuff plethysmography |
0.0 |
unx |
13 |
days |
|
|
|
101549 |
2602 |
SD |
plasma potassium level |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood potassium amount |
male |
0 days
| 6 |
|
|
4.5 |
mmol/l |
0.2 |
0.5 |
ex vivo blood analysis |
0.0 |
unx |
28 |
days |
|
|
|
101598 |
2602 |
SD |
plasma norepinephrine level |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood norepinephrine amount |
male |
175 days
| 8 |
|
|
102.0 |
pg/ml |
16.0 |
45.25 |
enzyme linked immunosorbent assay |
0.0 |
sham ACF |
105 |
days |
|
|
|
99285 |
2278 |
SD |
plasma epinephrine level |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood epinephrine amount |
male |
98 days
| 9 |
|
|
91.0 |
pg/ml |
21.0 |
63.0 |
enzyme linked immunosorbent assay |
0.0 |
ACF |
28 |
days |
|
|
|
99288 |
2278 |
SD |
heart rate |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
72 days
| 5 |
|
|
371.0 |
beats/min |
4.0 |
8.94 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99293 |
2278 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
72 days
| 5 |
|
|
100.0 |
mmHg |
2.0 |
4.47 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99299 |
2278 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
98 days
| 8 |
|
|
90.0 |
mmHg |
2.0 |
5.66 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99304 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
10.0 |
mmHg |
1.0 |
2.83 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99312 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
8116.0 |
mmHg/s |
348.0 |
984.29 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99328 |
2278 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 8 |
|
|
6.8 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99352 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
lvedd/pw |
|
4.5 |
null |
0.4 |
1.06 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
99361 |
2278 |
SD |
food intake rate |
acetaminophen (250 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50 days-64 days |
6 |
|
|
32.5 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84828 |
1602 |
SD |
heart right ventricle weight to body weight ratio |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right ventricle mass |
male |
189 days
| 10 |
|
|
0.52 |
mg/g |
0.01 |
0.03 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101105 |
2564 |
SD |
left atrium weight |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left atrium mass |
male |
189 days
| 6 |
|
|
0.04 |
g |
0.0 |
0.01 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101110 |
2564 |
SD |
heart right atrium weight to body weight ratio |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right atrium mass |
male |
189 days
| 10 |
|
|
0.09 |
mg/g |
0.01 |
0.03 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
raw/bw |
|
101121 |
2564 |
SD |
body weight |
left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 9 |
|
|
258.0 |
g |
3.0 |
9.0 |
body weighing method |
0.0 |
unx |
0 |
|
|
|
|
98927 |
2179 |
SD |
body weight |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 7 |
|
|
318.0 |
g |
15.0 |
39.69 |
body weighing method |
0.0 |
unx |
56 |
days |
|
|
|
98932 |
2179 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 9 |
|
|
6.4 |
null |
1.1 |
3.3 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
56 |
days |
|
|
|
98969 |
2179 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
13.3 |
null |
1.7 |
4.5 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
70 |
days |
|
|
|
98973 |
2179 |
SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
68.0 |
g/cm2 |
8.0 |
21.17 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99401 |
2278 |
SD |
hematocrit |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71 days-85 days |
6 |
|
|
45.25 |
% |
0.57 |
1.39 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84951 |
1602 |
SD |
hematocrit |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71 days-85 days |
6 |
|
|
45.1 |
% |
0.49 |
1.2 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84954 |
1602 |
SD |
hematocrit |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71 days-85 days |
6 |
|
|
40.85 |
% |
0.51 |
1.24 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84959 |
1602 |
SD |
heart wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
85 days-99 days |
6 |
|
|
0.33 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85234 |
1602 |
SD |
spleen wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
71 days-85 days |
6 |
|
|
0.22 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85242 |
1602 |
SD |
spleen wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
71 days-85 days |
6 |
|
|
0.21 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85245 |
1602 |
SD |
brain wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
85 days-99 days |
6 |
|
|
0.67 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85258 |
1602 |
SD |
adrenal gland wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
71 days-85 days |
6 |
|
|
0.04 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85274 |
1602 |
SD |
uterus wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
85 days-99 days |
6 |
|
|
0.35 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85288 |
1602 |
SD |
blood bilirubin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
female |
71 days-85 days |
6 |
|
|
0.44 |
mg/dl |
0.05 |
0.13 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85113 |
1602 |
SD |
blood sodium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
male |
71 days-85 days |
6 |
|
|
147.8 |
mmol/l |
0.7 |
1.72 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85122 |
1602 |
SD |
blood sodium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
male |
85 days-99 days |
6 |
|
|
104.23 |
mmol/l |
24.73 |
60.57 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85124 |
1602 |
SD |
blood glucose level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
female |
71 days-85 days |
6 |
|
|
181.5 |
mg/dl |
3.6 |
8.83 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84996 |
1602 |
SD |
plasma total protein level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
male |
71 days-85 days |
6 |
|
|
65.0 |
mg/ml |
0.94 |
2.3 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85014 |
1602 |
SD |
plasma total protein level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
female |
71 days-85 days |
6 |
|
|
64.0 |
mg/ml |
1.39 |
3.4 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85018 |
1602 |
SD |
blood creatinine level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
male |
71 days-85 days |
6 |
|
|
0.4 |
mg/dl |
0.02 |
0.06 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85060 |
1602 |
SD |
blood creatinine level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
male |
85 days-99 days |
6 |
|
|
0.37 |
mg/dl |
0.07 |
0.16 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85063 |
1602 |
SD |
blood creatinine level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
female |
71 days-85 days |
6 |
|
|
0.4 |
mg/dl |
0.03 |
0.08 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85065 |
1602 |
SD |
blood aspartate aminotransferase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
female |
71 days-85 days |
6 |
|
|
162.23 |
U/l |
8.83 |
21.64 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85077 |
1602 |
SD |
blood aspartate aminotransferase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
female |
85 days-99 days |
6 |
|
|
146.5 |
U/l |
7.35 |
18.01 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85082 |
1602 |
SD |
blood alanine aminotransferase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
female |
85 days-99 days |
6 |
|
|
49.67 |
U/l |
2.17 |
5.32 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85093 |
1602 |
SD |
blood alkaline phosphatase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
male |
85 days-99 days |
6 |
|
|
268.14 |
U/l |
48.98 |
119.97 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85099 |
1602 |
SD |
blood bilirubin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
male |
71 days-85 days |
6 |
|
|
0.41 |
mg/dl |
0.04 |
0.11 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85108 |
1602 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
70 days-84 days |
6 |
|
|
258.5 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84769 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 1 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
42 days-56 days |
6 |
|
|
182.4 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84775 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
57 days-71 days |
6 |
|
|
231.9 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84791 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
50 days-64 days |
6 |
|
|
148.3 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84795 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
64 days-78 days |
6 |
|
|
167.0 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84797 |
1602 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
50 days-64 days |
6 |
|
|
152.8 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84800 |
1602 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
70 days-84 days |
6 |
|
|
162.5 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84808 |
1602 |
SD |
food intake rate |
acetaminophen (500 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64 days-78 days |
6 |
|
|
39.4 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84834 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70 days-84 days |
6 |
|
|
31.0 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84839 |
1602 |
SD |
blood potassium level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
male |
71 days-85 days |
6 |
|
|
5.0 |
mmol/l |
0.15 |
0.36 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85133 |
1602 |
SD |
blood potassium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
male |
85 days-99 days |
6 |
|
|
3.88 |
mmol/l |
0.9 |
2.2 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85136 |
1602 |
SD |
blood potassium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
female |
85 days-99 days |
6 |
|
|
4.7 |
mmol/l |
0.11 |
0.28 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85141 |
1602 |
SD |
blood triglyceride level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
female |
71 days-85 days |
6 |
|
|
31.7 |
mg/dl |
2.0 |
4.89 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85188 |
1602 |
SD |
blood calcium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
male |
71 days-85 days |
6 |
|
|
10.0 |
mg/dl |
0.1 |
0.25 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85143 |
1602 |
SD |
blood calcium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
male |
71 days-85 days |
6 |
|
|
9.9 |
mg/dl |
0.04 |
0.11 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85146 |
1602 |
SD |
blood total cholesterol level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
female |
71 days-85 days |
6 |
|
|
102.3 |
mg/dl |
3.01 |
7.37 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85175 |
1602 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
64 days-78 days |
6 |
|
|
241.1 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84773 |
1602 |
SD |
blood albumin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
71 days-85 days |
6 |
|
|
3.3 |
g/dl |
0.1 |
0.25 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85000 |
1602 |
SD |
plasma total protein level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
male |
71 days-85 days |
6 |
|
|
63.0 |
mg/ml |
1.43 |
3.5 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85012 |
1602 |
SD |
blood globulin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
female |
71 days-85 days |
6 |
|
|
3.0 |
g/dl |
0.02 |
0.05 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85029 |
1602 |
SD |
blood bilirubin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
male |
71 days-85 days |
6 |
|
|
0.47 |
mg/dl |
0.04 |
0.11 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85110 |
1602 |
SD |
blood bilirubin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
female |
71 days-85 days |
6 |
|
|
1.33 |
mg/dl |
0.2 |
0.49 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85116 |
1602 |
SD |
heart wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
71 days-85 days |
6 |
|
|
0.37 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85231 |
1602 |
SD |
red blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
85 days-99 days |
6 |
|
|
8.64 |
x 10E6 cells/ul |
0.24 |
0.6 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84899 |
1602 |
SD |
blood differential white blood cell count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
71 days-85 days |
6 |
|
|
8.83 |
x 1000 cells/ul |
1.33 |
3.25 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84902 |
1602 |
SD |
red blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71 days-85 days |
6 |
|
|
8.97 |
x 10E6 cells/ul |
0.2 |
0.5 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84912 |
1602 |
SD |
hematocrit |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71 days-85 days |
6 |
|
|
40.22 |
% |
0.83 |
2.03 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84958 |
1602 |
SD |
hematocrit |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
85 days-99 days |
6 |
|
|
39.8 |
% |
0.63 |
1.55 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84961 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50 days-64 days |
6 |
|
|
21.8 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84860 |
1602 |
SD |
both kidneys wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
71 days-85 days |
6 |
|
|
0.88 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85214 |
1602 |
SD |
both lungs wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
71 days-85 days |
6 |
|
|
0.73 |
g |
0.09 |
0.23 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85218 |
1602 |
SD |
both lungs wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
85 days-99 days |
6 |
|
|
0.66 |
g |
0.06 |
0.14 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85222 |
1602 |
SD |
both lungs wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
71 days-85 days |
6 |
|
|
0.8 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85226 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
42 days-56 days |
6 |
|
|
184.1 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84781 |
1602 |
SD |
blood differential white blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
85 days-99 days |
6 |
|
|
8.19 |
x 1000 cells/ul |
0.53 |
1.31 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84891 |
1602 |
SD |
blood differential white blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
85 days-99 days |
6 |
|
|
8.34 |
x 1000 cells/ul |
0.79 |
1.94 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84893 |
1602 |
SD |
blood hemoglobin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
85 days-99 days |
6 |
|
|
13.9 |
g/dl |
0.2 |
0.5 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84943 |
1602 |
SD |
blood hemoglobin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
71 days-85 days |
6 |
|
|
11.57 |
g/dl |
0.38 |
0.92 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84946 |
1602 |
SD |
blood hemoglobin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
71 days-85 days |
6 |
|
|
11.9 |
g/dl |
0.16 |
0.4 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84947 |
1602 |
SD |
platelet count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
71 days-85 days |
6 |
|
|
816.0 |
x 1000 cells/ul |
44.32 |
108.56 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84981 |
1602 |
SD |
blood albumin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
71 days-85 days |
6 |
|
|
3.3 |
g/dl |
0.08 |
0.19 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85007 |
1602 |
SD |
blood albumin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
85 days-99 days |
6 |
|
|
3.62 |
g/dl |
0.04 |
0.09 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85010 |
1602 |
SD |
blood albumin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
71 days-85 days |
6 |
|
|
3.5 |
g/dl |
0.08 |
0.2 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85002 |
1602 |
SD |
systolic blood pressure |
controlled enalapril content drinking water (5 mg/kg/d) (for 10 days) |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
130 days
| 1 |
mean of 3 samples - 1 per minute |
serial mean |
117.0 |
mmHg |
|
|
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
102814 |
2439 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.2 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
360 |
min |
|
|
|
98786 |
2160 |
SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 5 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.7 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
5 |
days |
|
|
|
98791 |
2160 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
76.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98811 |
2160 |
SD |
mean arterial blood pressure |
sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
85.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
5 |
days |
|
|
|
98813 |
2160 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
82.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98817 |
2160 |
SD |
creatinine clearance |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
glomerular filtration trait |
male |
0 days
| 7 |
|
|
0.44 |
ml/min |
0.11 |
0.29 |
serum creatinine analysis |
0.0 |
unx |
70 |
days |
|
|
|
98994 |
2179 |
SD |
creatinine clearance |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
glomerular filtration trait |
male |
0 days
| 7 |
|
|
1.34 |
ml/min |
0.3 |
0.79 |
automated serum creatinine analysis |
0.0 |
unx |
70 |
days |
|
|
|
98996 |
2179 |
SD |
glomerular filtration rate to body weight ratio |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.67 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
stz |
154 |
days |
|
|
|
99902 |
2358 |
SD |
effective renal plasma flow |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney plasma flow trait |
male |
0 days
| 8 |
|
|
2.24 |
ml/min/100g |
0.06 |
0.18 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
99907 |
2358 |
SD |
blood urea nitrogen level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood urea nitrogen amount |
male |
140 days
| 6 |
|
|
34.2 |
mg/dl |
1.6 |
3.92 |
blood urea nitrogen analysis |
0.0 |
unx |
84 |
days |
|
|
|
100154 |
2419 |
SD |
body weight |
control condition |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
body mass |
female |
0 days
| 8 |
|
|
305.4 |
g |
5.3 |
14.99 |
body weighing method |
0.0 |
- |
0 |
days |
|
|
|
100631 |
2499 |
SD |
body weight |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
body mass |
female |
0 days
| 10 |
|
|
291.9 |
g |
6.4 |
20.24 |
body weighing method |
0.0 |
unx |
97 |
days |
|
|
|
100634 |
2499 |
SD |
serum creatinine level |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood creatinine amount |
female |
0 days
| 10 |
|
|
1.5 |
mg/dl |
0.11 |
0.35 |
serum creatinine analysis |
0.0 |
unx |
97 |
days |
|
|
|
100639 |
2499 |
SD |
creatinine clearance |
control condition |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
glomerular filtration trait |
female |
0 days
| 8 |
|
|
0.96 |
ml/min |
0.07 |
0.2 |
serum creatinine analysis |
0.0 |
- |
0 |
days |
|
|
|
100641 |
2499 |
SD |
serum parathyroid hormone level |
control condition |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood parathyroid hormone amount |
female |
0 days
| 8 |
|
|
83.0 |
pg/ml |
19.0 |
53.74 |
serum parathyroid hormone analysis |
0.0 |
- |
0 |
days |
|
|
|
100646 |
2499 |
SD |
serum parathyroid hormone level |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood parathyroid hormone amount |
female |
0 days
| 10 |
|
|
629.0 |
pg/ml |
208.0 |
657.75 |
serum parathyroid hormone analysis |
0.0 |
unx |
97 |
days |
|
|
|
100649 |
2499 |
SD |
serum parathyroid hormone level |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) and enalapril (25 mg/l) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood parathyroid hormone amount |
female |
0 days
| 12 |
|
|
170.0 |
pg/ml |
60.0 |
207.85 |
serum parathyroid hormone analysis |
0.0 |
unx |
97 |
days |
|
|
|
100650 |
2499 |
SD |
change in body weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 8 |
|
|
59.0 |
g |
10.96 |
31.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
change from surgery weight |
|
101609 |
2602 |
SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 8 |
|
|
1.96 |
g |
0.16 |
0.44 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101613 |
2602 |
SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 8 |
|
|
1.79 |
g |
0.12 |
0.35 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101614 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (for 14 days) then spironolactone (5.56 mg/kg/d) (for 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 8 |
|
|
130.0 |
mg/d |
19.09 |
54.0 |
urine protein analysis |
0.0 |
unx |
14 |
days |
|
|
|
101622 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 8 |
|
|
283.0 |
mg/d |
52.33 |
148.0 |
urine protein analysis |
0.0 |
unx |
28 |
days |
|
|
|
101623 |
2602 |
SD |
plasma potassium level |
unilateral nephrectomy (for 14 days) then spironolactone (5.56 mg/kg/d) (for 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood potassium amount |
male |
0 days
| 8 |
|
|
5.2 |
mmol/l |
0.14 |
0.4 |
ex vivo blood analysis |
0.0 |
unx |
14 |
days |
|
|
|
101626 |
2602 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 6 |
|
|
25.3 |
% |
4.53 |
11.1 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
|
|
101606 |
2602 |
SD |
body weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 5 |
|
|
285.0 |
g |
6.71 |
15.0 |
body weighing method |
0.0 |
unx |
13 |
days |
|
|
|
101537 |
2602 |
SD |
change in body weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 5 |
|
|
74.0 |
g |
7.6 |
17.0 |
body weighing method |
0.0 |
unx |
13 |
days |
|
change from surgery weight |
|
101541 |
2602 |
SD |
change in body weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 5 |
|
|
66.0 |
g |
4.92 |
11.0 |
body weighing method |
0.0 |
unx |
13 |
days |
|
change from surgery weight |
|
101542 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 11 |
|
|
121.0 |
mg/d |
16.28 |
54.0 |
urine protein analysis |
0.0 |
unx |
13 |
days |
|
- |
|
101552 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 5 |
|
|
31.0 |
mg/d |
5.37 |
12.0 |
urine protein analysis |
0.0 |
unx |
13 |
days |
|
|
|
101553 |
2602 |
SD |
adrenal gland weight |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 11 |
|
|
63.0 |
mg |
1.21 |
4.0 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
|
- |
|
101560 |
2602 |
SD |
plasma renin activity level |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
renin activity |
male |
0 days
| 11 |
|
|
4.3 |
ng/ml/h |
0.63 |
2.08 |
radioimmunoassay |
0.0 |
unx |
13 |
days |
|
- |
|
101564 |
2602 |
SD |
body weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 6 |
|
|
312.0 |
g |
9.8 |
24.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
|
|
101574 |
2602 |
SD |
change in body weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 7 |
|
|
96.0 |
g |
15.12 |
40.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
change from surgery weight |
|
101576 |
2602 |
SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 7 |
|
|
1.91 |
g |
0.21 |
0.55 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
remnant kidney |
|
101580 |
2602 |
SD |
systolic blood pressure |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 6 |
undefined |
|
118.0 |
mmHg |
4.08 |
10.0 |
tail cuff plethysmography |
0.0 |
sham unx |
28 |
days |
|
|
|
101583 |
2602 |
SD |
systolic blood pressure |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 7 |
undefined |
|
212.0 |
mmHg |
7.56 |
20.0 |
tail cuff plethysmography |
0.0 |
unx |
28 |
days |
|
|
|
101584 |
2602 |
SD |
systolic blood pressure |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 7 |
undefined |
|
109.0 |
mmHg |
4.16 |
11.0 |
tail cuff plethysmography |
0.0 |
unx |
28 |
days |
|
|
|
101585 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 6 |
|
|
217.0 |
mg/d |
28.99 |
71.0 |
urine protein analysis |
0.0 |
unx |
28 |
days |
|
|
|
101594 |
2602 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
7.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
5 |
days |
|
|
|
98824 |
2160 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
3.0 |
mmHg |
1.0 |
2.45 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98829 |
2160 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
66.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98835 |
2160 |
SD |
ejection fraction |
artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
cardiac output trait |
male |
0 days
| 6 |
|
|
66.0 |
% |
4.0 |
9.8 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
720 |
min |
|
|
|
98880 |
2160 |
SD |
ejection fraction |
sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
cardiac output trait |
male |
0 days
| 6 |
|
|
65.0 |
% |
3.0 |
7.35 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
2 |
days |
|
|
|
98883 |
2160 |
SD |
body weight |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
body mass |
male |
0 days
| 8 |
|
|
526.0 |
g |
10.25 |
29.0 |
body weighing method |
0.0 |
stz |
154 |
days |
|
|
|
99871 |
2358 |
SD |
mean arterial blood pressure |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
arterial blood pressure trait |
male |
420 days-450 days |
9 |
|
|
123.0 |
mmHg |
12.0 |
36.0 |
vascular fluid filled catheter |
0.0 |
|
0 |
|
|
|
|
101223 |
2582 |
SD |
renal plasma flow |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
kidney plasma flow trait |
male |
90 days
| 9 |
|
|
3.83 |
ml/min |
0.21 |
0.63 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
101228 |
2582 |
SD |
urine sodium excretion rate |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
urine sodium amount |
male |
90 days
| 9 |
|
|
1.4 |
mEq/d |
0.4 |
1.2 |
urine sodium analysis |
0.0 |
|
0 |
|
|
|
|
101236 |
2582 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 23 |
|
|
21.3 |
s |
3.9 |
18.7 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time to platform |
|
98239 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 23 |
|
|
18.9 |
s |
3.13 |
15.0 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
3 |
days |
|
time to platform |
|
98240 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 10 |
|
|
15.2 |
s |
2.75 |
8.7 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
3 |
days |
|
time in platform |
|
98246 |
2040 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 17 |
|
|
23.1 |
null |
2.69 |
11.1 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
|
|
98253 |
2040 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 11 |
|
|
1168.0 |
null |
109.45 |
363.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
|
|
98254 |
2040 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 9 |
|
|
18.4 |
null |
2.83 |
8.5 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
|
|
98256 |
2040 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 11 |
|
|
90.8 |
s |
10.64 |
35.3 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
time in open arms |
|
98259 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 9 |
|
|
31.0 |
s |
5.13 |
15.4 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
29 |
days |
|
time in platform |
|
98274 |
2040 |
SD |
body weight |
artificial aortocaval fistula (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
body mass |
male |
0 days
| 6 |
|
|
267.0 |
g |
4.0 |
9.8 |
body weighing method |
1.0 |
ACF |
720 |
min |
|
|
|
98771 |
2160 |
SD |
heart weight to body weight ratio |
sham surgical control condition (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
0 days
| 6 |
g/g*103 |
|
3.3 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
2 |
days |
|
|
|
98782 |
2160 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
7.3 |
mm |
0.3 |
0.73 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
720 |
min |
|
|
|
98845 |
2160 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
7.1 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
2 |
days |
|
|
|
98847 |
2160 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
7.1 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
5 |
days |
|
|
|
98849 |
2160 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-systolic diameter |
male |
0 days
| 6 |
|
|
3.8 |
mm |
0.4 |
0.98 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
360 |
min |
|
|
|
98850 |
2160 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-systolic diameter |
male |
0 days
| 6 |
|
|
4.0 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
2 |
days |
|
|
|
98855 |
2160 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-systolic diameter |
male |
0 days
| 6 |
|
|
3.9 |
mm |
0.3 |
0.73 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
5 |
days |
|
|
|
98857 |
2160 |
SD |
maximum rate of positive change in left ventricular blood pressure |
sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
8231.0 |
mmHg/s |
423.0 |
1036.13 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98887 |
2160 |
SD |
maximum rate of negative change in left ventricular blood pressure |
artificial aortocaval fistula (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
-6032.0 |
mmHg/s |
387.0 |
947.95 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98890 |
2160 |
SD |
body weight |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 7 |
|
|
267.0 |
g |
7.0 |
18.52 |
body weighing method |
0.0 |
unx |
70 |
days |
|
|
|
98935 |
2179 |
SD |
body weight |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 9 |
|
|
281.0 |
g |
15.0 |
45.0 |
body weighing method |
0.0 |
unx |
70 |
days |
|
|
|
98936 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 7 |
|
|
148.0 |
mmHg |
4.0 |
10.58 |
tail cuff plethysmography |
0.0 |
unx |
28 |
days |
|
|
|
98943 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 9 |
|
|
153.0 |
mmHg |
8.0 |
24.0 |
tail cuff plethysmography |
0.0 |
unx |
56 |
days |
|
|
|
98945 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 9 |
|
|
0.7 |
mg/d |
0.1 |
0.3 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
0 |
|
|
|
|
98951 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
0.9 |
mg/d |
0.1 |
0.26 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
0 |
|
|
|
|
98952 |
2179 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 23 |
|
|
1131.0 |
cm |
81.74 |
392.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98213 |
2040 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 10 |
|
|
1334.0 |
cm |
84.43 |
267.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98215 |
2040 |
SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
|
50.0 |
% |
3.0 |
6.71 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99366 |
2278 |
SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
|
37.0 |
% |
1.0 |
2.83 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99368 |
2278 |
SD |
ejection fraction |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
72 days
| 5 |
|
|
72.0 |
% |
2.0 |
4.47 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
|
|
99373 |
2278 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 8 |
|
|
42.2 |
s |
10.47 |
29.6 |
elevated plus maze apparatus method |
300.0 |
sham coronal plane rotational acceleration of the head |
2 |
days |
|
time in open arms |
|
98222 |
2040 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 10 |
|
|
98.1 |
s |
9.42 |
29.8 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time in open arms |
|
98227 |
2040 |
SD |
body weight |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
body mass |
male |
98 days
| 8 |
|
|
359.0 |
g |
20.0 |
56.57 |
scale |
0.0 |
sham ACF |
28 |
days |
|
|
|
99191 |
2278 |
SD |
body weight |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
body mass |
male |
175 days
| 10 |
|
|
489.0 |
g |
15.0 |
47.43 |
scale |
0.0 |
ACF |
105 |
days |
|
|
|
99194 |
2278 |
SD |
heart weight to body weight ratio |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
175 days
| 10 |
|
|
2.7 |
g/kg |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
|
|
99201 |
2278 |
SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle mass |
male |
98 days
| 8 |
|
|
3.1 |
mg/g |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
|
|
99204 |
2278 |
SD |
heart right ventricle weight to body weight ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart right ventricle mass |
male |
98 days
| 8 |
|
|
0.9 |
mg/g |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
|
|
99208 |
2278 |
SD |
lung weight |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
lung mass |
male |
98 days
| 8 |
|
|
1.46 |
g |
0.09 |
0.25 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
|
|
99211 |
2278 |
SD |
lung weight |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
lung mass |
male |
175 days
| 10 |
|
|
2.44 |
g |
0.11 |
0.35 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
|
|
99214 |
2278 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
98 days
| 8 |
|
|
114.0 |
mmHg |
4.0 |
11.31 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99219 |
2278 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
98 days
| 8 |
|
|
95.0 |
mmHg |
3.0 |
8.49 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99220 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
2.0 |
mmHg |
1.0 |
2.83 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99223 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
6600.0 |
mmHg/s |
289.0 |
913.9 |
vascular transducer tipped catheter |
0.0 |
ACF |
105 |
days |
|
|
|
99230 |
2278 |
SD |
systolic blood pressure |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
arterial blood pressure trait |
male |
140 days
| 6 |
|
serial mean |
142.8 |
mmHg |
6.4 |
15.68 |
tail cuff plethysmography |
0.0 |
unx |
84 |
days |
|
|
|
100114 |
2419 |
SD |
blood glucose level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood glucose amount |
male |
140 days
| 6 |
|
|
138.6 |
mg/dl |
10.3 |
25.23 |
blood glucose analysis |
0.0 |
unx |
84 |
days |
|
|
|
100124 |
2419 |
SD |
blood hemoglobin A1c level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood hemoglobin amount |
male |
140 days
| 6 |
|
|
3.2 |
% |
0.1 |
0.24 |
blood hemoglobin analysis |
0.0 |
unx |
84 |
days |
|
|
|
100128 |
2419 |
SD |
blood hemoglobin A1c level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood hemoglobin amount |
male |
140 days
| 8 |
|
|
3.2 |
% |
0.1 |
0.28 |
tail cuff plethysmography |
0.0 |
unx |
84 |
days |
|
|
|
100130 |
2419 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (140 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 14 |
|
|
37.5 |
s |
3.02 |
11.3 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
1 |
days |
|
time to platform |
|
98232 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (140 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 14 |
|
|
15.8 |
s |
2.89 |
10.8 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time to platform |
|
98233 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 21 |
|
|
23.1 |
s |
3.58 |
16.4 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time to platform |
|
98236 |
2040 |
SD |
maximum rate of negative change in left ventricular blood pressure |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
-6995.0 |
mmHg/s |
458.0 |
1295.42 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99232 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
-5401.0 |
mmHg/s |
358.0 |
1132.1 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
105 |
days |
|
|
|
99233 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
-4244.0 |
mmHg/s |
222.0 |
702.03 |
vascular transducer tipped catheter |
0.0 |
ACF |
105 |
days |
|
|
|
99234 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
|
|
9.0 |
mm |
0.1 |
0.32 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
|
|
99237 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
|
|
11.6 |
mm |
0.4 |
1.26 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
|
|
99238 |
2278 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 8 |
|
|
6.3 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99240 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
lvedd/pw |
|
7.9 |
null |
0.4 |
1.26 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
heart left ventricle end-diastolic dimeter to posterior wall thickness ratio |
|
99246 |
2278 |
SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
3.0 |
g/cm2 |
1.0 |
2.83 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99247 |
2278 |
SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
14.0 |
g/cm2 |
3.0 |
8.49 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99248 |
2278 |
SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
67.0 |
g/cm2 |
13.0 |
36.77 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99251 |
2278 |
SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
|
38.0 |
% |
4.0 |
11.31 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99255 |
2278 |
SD |
heart left ventricle interstitial angiotensin II level during a period of time |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial angiotensin II amount |
male |
98 days
| 8 |
|
|
1.5 |
pg/hr |
0.2 |
0.57 |
radioimmunoassay |
0.0 |
sham ACF |
28 |
days |
|
heart left ventricle interstitial angiotensin II level during a period of time |
|
99259 |
2278 |
SD |
heart left ventricle interstitial bradykinin level during a period of time |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial bradykinin amount |
male |
98 days
| 9 |
|
|
9.3 |
pg/hr |
1.1 |
3.3 |
radioimmunoassay |
0.0 |
ACF |
28 |
days |
|
heart left ventricle interstitial bradykinin level during a period of time |
|
99264 |
2278 |
SD |
heart left ventricle interstitial epinephrine level during a period of time |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial epinephrine amount |
male |
98 days
| 8 |
|
|
3.5 |
pg/hr |
0.3 |
0.85 |
enzyme linked immunosorbent assay |
0.0 |
sham ACF |
28 |
days |
|
heart left ventricle interstitial epinephrine level during a period of time |
|
99271 |
2278 |
SD |
heart left ventricle interstitial epinephrine level during a period of time |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial epinephrine amount |
male |
98 days
| 9 |
|
|
5.3 |
pg/hr |
0.9 |
2.7 |
enzyme linked immunosorbent assay |
0.0 |
ACF |
28 |
days |
|
heart left ventricle interstitial epinephrine level during a period of time |
|
99272 |
2278 |
SD |
heart left ventricle interstitial epinephrine level during a period of time |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial epinephrine amount |
male |
175 days
| 8 |
|
|
3.5 |
pg/hr |
0.4 |
1.13 |
enzyme linked immunosorbent assay |
0.0 |
sham ACF |
105 |
days |
|
heart left ventricle interstitial epinephrine level during a period of time |
|
99273 |
2278 |
SD |
plasma angiotensin II level |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood angiotensin II amount |
male |
175 days
| 8 |
|
|
34.0 |
pg/ml |
4.0 |
11.31 |
radioimmunoassay |
0.0 |
sham ACF |
105 |
days |
|
|
|
99277 |
2278 |
SD |
plasma angiotensin II level |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood angiotensin II amount |
male |
175 days
| 10 |
|
|
65.0 |
pg/ml |
13.0 |
41.11 |
radioimmunoassay |
0.0 |
ACF |
105 |
days |
|
|
|
99278 |
2278 |
SD |
plasma norepinephrine level |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood norepinephrine amount |
male |
175 days
| 10 |
|
|
159.0 |
pg/ml |
17.0 |
53.76 |
enzyme linked immunosorbent assay |
0.0 |
ACF |
105 |
days |
|
|
|
99286 |
2278 |
SD |
heart rate |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
72 days
| 5 |
|
|
367.0 |
beats/min |
8.0 |
17.89 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99292 |
2278 |
SD |
heart rate |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
72 days
| 5 |
|
|
375.0 |
beats/min |
12.0 |
26.83 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99294 |
2278 |
SD |
heart rate |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
98 days
| 8 |
|
|
316.0 |
beats/min |
3.0 |
8.49 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99298 |
2278 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
98 days
| 7 |
|
|
106.0 |
mmHg |
5.0 |
13.23 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99305 |
2278 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
98 days
| 8 |
|
|
86.0 |
mmHg |
2.0 |
5.66 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99306 |
2278 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
61.0 |
mmHg |
3.0 |
6.71 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99316 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
-6834.0 |
mmHg/s |
333.0 |
941.87 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99337 |
2278 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 7 |
|
|
4.7 |
mm |
0.2 |
0.53 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99353 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
lvedd/pw |
|
5.7 |
null |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
99360 |
2278 |
SD |
body weight |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
body mass |
male |
77 days
| 6 |
|
|
378.1 |
g |
12.1 |
29.64 |
body weighing method |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101076 |
2564 |
SD |
systolic blood pressure |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
arterial blood pressure trait |
male |
77 days
| 6 |
undefined |
|
125.0 |
mmHg |
3.0 |
7.35 |
tail cuff plethysmography |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101087 |
2564 |
SD |
systolic blood pressure |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
arterial blood pressure trait |
male |
189 days
| 6 |
undefined |
|
144.0 |
mmHg |
2.0 |
4.9 |
tail cuff plethysmography |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101090 |
2564 |
SD |
heart left ventricle weight |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle mass |
male |
77 days
| 6 |
|
|
0.6 |
g |
0.02 |
0.05 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101092 |
2564 |
SD |
heart left ventricle weight to body weight ratio |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle mass |
male |
77 days
| 6 |
|
|
1.67 |
mg/g |
0.04 |
0.1 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101095 |
2564 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle mass |
male |
77 days
| 6 |
|
|
1.56 |
mg/g |
0.03 |
0.07 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101096 |
2564 |
SD |
heart right ventricle weight |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right ventricle mass |
male |
189 days
| 10 |
|
|
0.29 |
g |
0.01 |
0.03 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101101 |
2564 |
SD |
heart right ventricle weight |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right ventricle mass |
male |
189 days
| 6 |
|
|
0.27 |
g |
0.01 |
0.02 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101102 |
2564 |
SD |
heart right ventricle weight to body weight ratio |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right ventricle mass |
male |
77 days
| 6 |
|
|
0.59 |
mg/g |
0.01 |
0.02 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101104 |
2564 |
SD |
heart left ventricle infarction area to total heart left ventricle area ratio |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle integrity trait |
male |
77 days
| 6 |
|
|
35.4 |
% |
1.9 |
4.65 |
ex vivo visual assessment |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101127 |
2564 |
SD |
heart left ventricle infarction area to total heart left ventricle area ratio |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle integrity trait |
male |
189 days
| 10 |
|
|
37.9 |
% |
2.0 |
6.32 |
ex vivo visual assessment |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101128 |
2564 |
SD |
blood albumin level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood albumin amount |
male |
140 days
| 6 |
|
|
3.2 |
g/dl |
0.2 |
0.49 |
automated blood albumin analysis |
0.0 |
unx |
84 |
days |
|
|
|
100165 |
2419 |
SD |
plasma urea nitrogen level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood urea nitrogen amount |
male |
120 days
| 3 |
|
|
6.78 |
mmol/l |
0.41 |
0.71 |
plasma urea nitrogen analysis |
0.0 |
|
0 |
|
|
|
|
100200 |
2439 |
SD |
plasma urea nitrogen level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood urea nitrogen amount |
male |
180 days
| 5 |
|
|
6.43 |
mmol/l |
0.21 |
0.36 |
plasma urea nitrogen analysis |
0.0 |
|
0 |
|
|
|
|
100202 |
2439 |
SD |
serum creatinine level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood creatinine amount |
male |
120 days
| 3 |
|
|
0.55 |
mg/dl |
0.01 |
0.01 |
serum creatinine analysis |
0.0 |
|
0 |
|
|
|
|
100206 |
2439 |
SD |
serum creatinine level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood creatinine amount |
male |
180 days
| 5 |
|
|
0.55 |
mg/dl |
0.06 |
0.1 |
serum creatinine analysis |
0.0 |
|
0 |
|
|
|
|
100208 |
2439 |
SD |
body weight |
sham surgical control condition (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
body mass |
male |
0 days
| 6 |
|
|
291.0 |
g |
10.0 |
24.49 |
body weighing method |
1.0 |
sham ACF |
360 |
min |
|
|
|
98756 |
2160 |
SD |
ejection fraction |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
98 days
| 7 |
|
|
67.0 |
% |
2.0 |
5.29 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99377 |
2278 |
SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
16.0 |
g/cm2 |
1.0 |
2.24 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99388 |
2278 |
SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
4.0 |
g/cm2 |
1.0 |
2.65 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99393 |
2278 |
SD |
ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial collagen amount |
male |
98 days
| 7 |
|
|
3.5 |
% |
0.1 |
0.26 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
sham ACF |
28 |
days |
|
|
|
99407 |
2278 |
SD |
ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial collagen amount |
male |
98 days
| 8 |
|
|
3.5 |
% |
0.1 |
0.28 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
ACF |
28 |
days |
|
|
|
99409 |
2278 |
SD |
renal filtration fraction |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.29 |
null |
0.01 |
0.02 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
stz |
154 |
days |
GFR by inulin method |
|
|
99912 |
2358 |
SD |
body weight |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
body mass |
male |
0 days
| 8 |
|
|
588.0 |
g |
27.58 |
78.0 |
body weighing method |
0.0 |
stz |
224 |
days |
|
|
|
99914 |
2358 |
SD |
plasma nifedipine level |
nifedipine (200 ug/kg) |
Lu J, et al., Sci Rep. 2017 Feb 20;7:42922. doi: 10.1038/srep42922. |
blood xenobiotic amount |
both |
56 days
| 6 |
|
|
926.52 |
ng/ml |
142.87 |
349.96 |
liquid chromatography-mass spectrometry |
0.0 |
|
0 |
|
2 hour tail vein blood sampling |
intial concentration nifidepine |
|
105708 |
3020 |
SD |
retinal uptake index of digoxin |
tritiated digoxin (10 uCi) (for 0 hours) and digoxin (0.01 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
26.3 |
% |
5.7 |
9.87 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
digoxin uptake index |
|
106118 |
3028 |
SD |
brain uptake index of verapamil |
tritiated verapamil (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
9.07 |
% |
0.89 |
1.54 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
verapamil uptake index |
|
106156 |
3028 |
SD |
aqueous humor uptake index of verapamil |
tritiated verapamil (10 uCi) (for 0 hours) and vinblastine (1 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
15.7 |
% |
1.0 |
1.73 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
verapamil uptake index |
|
106139 |
3028 |
SD |
aqueous humor uptake index of verapamil |
tritiated verapamil (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
23.1 |
% |
6.4 |
11.09 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
verapamil uptake index |
|
106140 |
3028 |
SD |
serum total immunoglobulin E level |
acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood immunoglobulin E amount |
not specified |
0 days
| 12 |
|
|
0.1 |
ug/l |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105408 |
3015 |
SD |
serum interleukin-4 level |
vehicle control condition then acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood interleukin-4 amount |
not specified |
0 days
| 4 |
|
|
0.14 |
ug/l |
0.01 |
0.01 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105411 |
3015 |
SD |
intestine trypsin level |
control condition |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
intestine trypsin amount |
not specified |
0 days
| 8 |
|
|
0.08 |
ug/l |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105418 |
3015 |
SD |
urine total protein excretion rate |
control condition |
Eisenberger U, etal., Ren Physiol Biochem. 1995 Mar-Apr;18(2):89-96. doi: 10.1159/000173904. |
total urine protein amount |
female |
96 days-121 days |
7 |
|
|
2.2 |
mg/d |
0.53 |
1.4 |
Bradford protein assay |
0.0 |
|
0 |
|
|
|
records do not display, fixed. |
110184 |
3166 |
SD |
serum creatinine level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood creatinine amount |
male |
60 days
| 3 |
|
|
0.53 |
mg/dl |
0.02 |
0.04 |
serum creatinine analysis |
0.0 |
|
0 |
|
|
|
|
100204 |
2439 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64 days-78 days |
6 |
|
|
26.6 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84862 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57 days-71 days |
6 |
|
|
20.0 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84869 |
1602 |
SD |
plasma total protein level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
female |
71 days-85 days |
6 |
|
|
62.0 |
mg/ml |
0.9 |
2.2 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85019 |
1602 |
SD |
plasma total protein level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
female |
85 days-99 days |
6 |
|
|
67.0 |
mg/ml |
0.61 |
1.5 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85022 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
71 days-85 days |
6 |
|
|
1.0 |
null |
0.05 |
0.13 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85056 |
1602 |
SD |
blood creatinine level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
female |
71 days-85 days |
6 |
|
|
1.1 |
mg/dl |
0.15 |
0.36 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85068 |
1602 |
SD |
blood alanine aminotransferase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
female |
85 days-99 days |
6 |
|
|
42.5 |
U/l |
1.15 |
2.81 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85092 |
1602 |
SD |
blood alkaline phosphatase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
male |
71 days-85 days |
6 |
|
|
298.5 |
U/l |
41.58 |
101.85 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85095 |
1602 |
SD |
heart wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
71 days-85 days |
6 |
|
|
0.37 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85233 |
1602 |
SD |
heart wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
85 days-99 days |
6 |
|
|
0.41 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85241 |
1602 |
SD |
spleen wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
71 days-85 days |
6 |
|
|
0.24 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85249 |
1602 |
SD |
brain wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
71 days-85 days |
6 |
|
|
0.77 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85254 |
1602 |
SD |
brain wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
71 days-85 days |
6 |
|
|
1.11 |
g |
0.05 |
0.12 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85262 |
1602 |
SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
85 days-99 days |
6 |
|
|
0.04 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85276 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
50 days-64 days |
6 |
|
|
205.4 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84782 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
64 days-78 days |
6 |
|
|
159.1 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84817 |
1602 |
SD |
blood hemoglobin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
71 days-85 days |
6 |
|
|
13.98 |
g/dl |
0.2 |
0.5 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84942 |
1602 |
SD |
blood hemoglobin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
71 days-85 days |
6 |
|
|
11.28 |
g/dl |
0.41 |
1.01 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84945 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
71 days-85 days |
6 |
|
|
11.57 |
% |
0.14 |
0.34 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84963 |
1602 |
SD |
blood glucose level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
female |
85 days-99 days |
6 |
|
|
82.67 |
mg/dl |
9.41 |
23.04 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84997 |
1602 |
SD |
blood potassium level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
female |
71 days-85 days |
6 |
|
|
4.75 |
mmol/l |
0.22 |
0.54 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85139 |
1602 |
SD |
blood total cholesterol level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
female |
71 days-85 days |
6 |
|
|
92.2 |
mg/dl |
5.71 |
13.98 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85174 |
1602 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.3 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
720 |
min |
|
|
|
98788 |
2160 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (between 120 and 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.3 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
5 |
days |
|
|
|
98792 |
2160 |
SD |
heart rate |
sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
389.0 |
beats/min |
9.0 |
22.05 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
2 |
days |
|
|
|
98798 |
2160 |
SD |
heart rate |
sham surgical control condition (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
365.0 |
beats/min |
7.0 |
17.15 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
2 |
days |
|
|
|
98805 |
2160 |
SD |
serum creatinine level |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then enalapril (25 mg/l) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
blood creatinine amount |
female |
0 days
| 12 |
|
|
0.93 |
mg/dl |
0.02 |
0.07 |
serum creatinine analysis |
0.0 |
unx |
97 |
days |
|
|
|
100638 |
2499 |
SD |
blood phosphate level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
female |
71 days-85 days |
6 |
|
|
5.6 |
mg/dl |
0.13 |
0.32 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85161 |
1602 |
SD |
liver wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
71 days-85 days |
6 |
|
|
3.7 |
g |
0.11 |
0.28 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85203 |
1602 |
SD |
duration of loss of righting reflex |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
balance trait |
female |
0 days
| 34 |
|
|
228.0 |
s |
14.75 |
86.0 |
visual assessment of in vivo video recording |
0.0 |
|
0 |
|
|
time to rigthing reflex post anesthesia |
|
98201 |
2040 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
3.0 |
mmHg |
1.0 |
2.45 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98827 |
2160 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
72.0 |
mmHg |
4.0 |
9.8 |
vascular transducer tipped catheter |
1.0 |
ACF |
360 |
min |
|
|
|
98830 |
2160 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
56.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98838 |
2160 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.3 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
2 |
days |
|
|
|
98875 |
2160 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 16 |
|
|
34.0 |
null |
2.95 |
11.8 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98220 |
2040 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70 days-84 days |
6 |
|
|
27.9 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84843 |
1602 |
SD |
change in body weight |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 11 |
|
|
66.0 |
g |
7.84 |
26.0 |
body weighing method |
0.0 |
unx |
13 |
days |
|
change from surgery weight |
|
101540 |
2602 |
SD |
heart wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
0 days
| 7 |
|
|
0.88 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101589 |
2602 |
SD |
urine total protein excretion rate |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 6 |
|
|
19.0 |
mg/d |
2.45 |
6.0 |
urine protein analysis |
0.0 |
sham unx |
28 |
days |
|
|
|
101591 |
2602 |
SD |
plasma potassium level |
unilateral nephrectomy (for 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood potassium amount |
male |
0 days
| 8 |
|
|
5.3 |
mmol/l |
0.14 |
0.4 |
ex vivo blood analysis |
0.0 |
unx |
14 |
days |
|
|
|
101625 |
2602 |
SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
15.0 |
g/cm2 |
2.0 |
5.66 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99392 |
2278 |
SD |
ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial collagen amount |
male |
72 days
| 5 |
|
|
3.9 |
% |
0.2 |
0.45 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
sham ACF |
2 |
days |
|
interstitial collagen |
|
99403 |
2278 |
SD |
ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial collagen amount |
male |
72 days
| 5 |
|
|
3.6 |
% |
0.2 |
0.45 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
ACF |
2 |
days |
|
|
|
99406 |
2278 |
SD |
red blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71 days-85 days |
6 |
|
|
8.64 |
x 10E6 cells/ul |
0.16 |
0.39 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84897 |
1602 |
SD |
blood differential white blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
71 days-85 days |
6 |
|
|
9.48 |
x 1000 cells/ul |
0.6 |
1.46 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84905 |
1602 |
SD |
plasma epinephrine level |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood epinephrine amount |
male |
175 days
| 10 |
|
|
101.0 |
pg/ml |
11.0 |
34.79 |
enzyme linked immunosorbent assay |
0.0 |
ACF |
105 |
days |
|
|
|
99290 |
2278 |
SD |
left ventricular end-systolic blood pressure |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
75.0 |
mmHg |
2.0 |
5.66 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99320 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
8767.0 |
mmHg/s |
391.0 |
874.3 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99323 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
-8474.0 |
mmHg/s |
123.0 |
275.04 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99333 |
2278 |
SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
|
43.0 |
% |
2.0 |
4.47 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
|
|
99365 |
2278 |
SD |
ejection fraction |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
72 days
| 5 |
|
|
66.0 |
% |
3.0 |
6.71 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
|
|
99371 |
2278 |
SD |
blood bilirubin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
female |
71 days-85 days |
6 |
|
|
0.34 |
mg/dl |
0.02 |
0.06 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85114 |
1602 |
SD |
blood sodium level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
male |
71 days-85 days |
6 |
|
|
144.7 |
mmol/l |
0.33 |
0.82 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85120 |
1602 |
SD |
blood sodium level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
male |
71 days-85 days |
6 |
|
|
145.2 |
mmol/l |
0.6 |
1.47 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85121 |
1602 |
SD |
blood sodium level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
female |
71 days-85 days |
6 |
|
|
146.67 |
mmol/l |
0.49 |
1.21 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85127 |
1602 |
SD |
blood sodium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood sodium amount |
female |
85 days-99 days |
6 |
|
|
144.33 |
mmol/l |
0.21 |
0.52 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85129 |
1602 |
SD |
blood phosphate level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
male |
71 days-85 days |
6 |
|
|
6.0 |
mg/dl |
0.07 |
0.16 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85156 |
1602 |
SD |
blood phosphate level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
male |
71 days-85 days |
6 |
|
|
6.1 |
mg/dl |
0.22 |
0.55 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85157 |
1602 |
SD |
blood total cholesterol level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
female |
71 days-85 days |
6 |
|
|
96.5 |
mg/dl |
6.17 |
15.11 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85176 |
1602 |
SD |
both kidneys wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
71 days-85 days |
6 |
|
|
0.88 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85209 |
1602 |
SD |
heart wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
71 days-85 days |
6 |
|
|
0.37 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85232 |
1602 |
SD |
heart wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
71 days-85 days |
6 |
|
|
0.4 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85236 |
1602 |
SD |
heart wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
71 days-85 days |
6 |
|
|
0.42 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85239 |
1602 |
SD |
spleen wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
71 days-85 days |
6 |
|
|
0.26 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85250 |
1602 |
SD |
spleen wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
85 days-99 days |
6 |
|
|
0.24 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85251 |
1602 |
SD |
brain wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
71 days-85 days |
6 |
|
|
1.17 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85263 |
1602 |
SD |
adrenal gland wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
71 days-85 days |
6 |
|
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85269 |
1602 |
SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
85 days-99 days |
6 |
|
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85270 |
1602 |
SD |
adrenal gland wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
71 days-85 days |
6 |
|
|
0.04 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85275 |
1602 |
SD |
testis wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
71 days-85 days |
6 |
|
|
1.17 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85280 |
1602 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
70 days-84 days |
6 |
|
|
256.6 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84774 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
50 days-64 days |
6 |
|
|
211.6 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84776 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
57 days-71 days |
6 |
|
|
229.6 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84777 |
1602 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
70 days-84 days |
6 |
|
|
175.3 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84803 |
1602 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
57 days-71 days |
6 |
|
|
151.9 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84806 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
50 days-64 days |
6 |
|
|
146.1 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84820 |
1602 |
SD |
food intake rate |
acetaminophen (500 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57 days-71 days |
6 |
|
|
36.7 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84833 |
1602 |
SD |
food intake rate |
acetaminophen (250 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57 days-71 days |
6 |
|
|
23.0 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84853 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50 days-64 days |
6 |
|
|
18.4 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84864 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64 days-78 days |
6 |
|
|
24.9 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84866 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70 days-84 days |
6 |
|
|
20.4 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84867 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64 days-78 days |
6 |
|
|
24.6 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84870 |
1602 |
SD |
blood glucose level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
female |
85 days-99 days |
6 |
|
|
90.83 |
mg/dl |
4.2 |
10.28 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84998 |
1602 |
SD |
plasma total protein level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
male |
85 days-99 days |
6 |
|
|
54.3 |
mg/ml |
10.45 |
25.6 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85015 |
1602 |
SD |
plasma total protein level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
female |
71 days-85 days |
6 |
|
|
83.0 |
mg/ml |
3.84 |
9.4 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85020 |
1602 |
SD |
blood urea nitrogen level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
male |
71 days-85 days |
6 |
|
|
14.5 |
mg/dl |
0.72 |
1.76 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85036 |
1602 |
SD |
blood urea nitrogen level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
male |
71 days-85 days |
6 |
|
|
15.5 |
mg/dl |
0.76 |
1.85 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85038 |
1602 |
SD |
blood urea nitrogen level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
male |
85 days-99 days |
6 |
|
|
13.56 |
mg/dl |
2.41 |
5.9 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85039 |
1602 |
SD |
blood urea nitrogen level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
female |
71 days-85 days |
6 |
|
|
18.7 |
mg/dl |
0.56 |
1.37 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85041 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
71 days-85 days |
6 |
|
|
0.9 |
null |
0.01 |
0.03 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85049 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
71 days-85 days |
6 |
|
|
0.9 |
null |
0.02 |
0.04 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85050 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
85 days-99 days |
6 |
|
|
0.66 |
null |
0.15 |
0.37 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85052 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
85 days-99 days |
6 |
|
|
0.97 |
null |
0.04 |
0.09 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85058 |
1602 |
SD |
blood aspartate aminotransferase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
male |
71 days-85 days |
6 |
|
|
178.5 |
U/l |
14.68 |
35.95 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85074 |
1602 |
SD |
blood aspartate aminotransferase activity level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
female |
71 days-85 days |
6 |
|
|
116.83 |
U/l |
7.25 |
17.76 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85079 |
1602 |
SD |
blood alanine aminotransferase activity level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
female |
71 days-85 days |
6 |
|
|
57.33 |
U/l |
1.33 |
3.27 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85090 |
1602 |
SD |
blood phosphate level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
female |
85 days-99 days |
6 |
|
|
5.45 |
mg/dl |
0.26 |
0.63 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85165 |
1602 |
SD |
liver wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
71 days-85 days |
6 |
|
|
3.81 |
g |
0.09 |
0.21 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85191 |
1602 |
SD |
blood potassium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
male |
85 days-99 days |
6 |
|
|
4.6 |
mmol/l |
0.87 |
2.14 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85135 |
1602 |
SD |
liver wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
71 days-85 days |
6 |
|
|
3.64 |
g |
0.12 |
0.3 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85200 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
57 days-71 days |
6 |
|
|
225.6 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84762 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
50 days-64 days |
6 |
|
|
143.7 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84815 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50 days-64 days |
6 |
|
|
39.5 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84844 |
1602 |
SD |
blood globulin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
male |
71 days-85 days |
6 |
|
|
2.9 |
g/dl |
0.03 |
0.08 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85023 |
1602 |
SD |
blood globulin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
male |
71 days-85 days |
6 |
|
|
3.0 |
g/dl |
0.05 |
0.13 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85024 |
1602 |
SD |
blood globulin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
female |
71 days-85 days |
6 |
|
|
2.9 |
g/dl |
0.04 |
0.09 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85031 |
1602 |
SD |
blood globulin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
female |
71 days-85 days |
6 |
|
|
3.8 |
g/dl |
0.21 |
0.51 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85032 |
1602 |
SD |
blood creatinine level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
female |
71 days-85 days |
6 |
|
|
0.3 |
mg/dl |
0.02 |
0.05 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85067 |
1602 |
SD |
blood alkaline phosphatase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
female |
85 days-99 days |
6 |
|
|
178.67 |
U/l |
18.2 |
44.59 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85105 |
1602 |
SD |
blood alkaline phosphatase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
female |
85 days-99 days |
6 |
|
|
228.17 |
U/l |
50.27 |
123.14 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85106 |
1602 |
SD |
blood bilirubin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
female |
85 days-99 days |
6 |
|
|
0.6 |
mg/dl |
0.04 |
0.1 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85117 |
1602 |
SD |
blood differential white blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
71 days-85 days |
6 |
|
|
6.1 |
x 1000 cells/ul |
0.56 |
1.38 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84901 |
1602 |
SD |
blood differential white blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
85 days-99 days |
6 |
|
|
8.68 |
x 1000 cells/ul |
1.91 |
4.68 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84907 |
1602 |
SD |
red blood cell count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71 days-85 days |
6 |
|
|
8.61 |
x 10E6 cells/ul |
0.22 |
0.54 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84909 |
1602 |
SD |
hematocrit |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71 days-85 days |
6 |
|
|
44.05 |
% |
0.46 |
1.13 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84953 |
1602 |
SD |
hematocrit |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
85 days-99 days |
6 |
|
|
45.68 |
% |
0.45 |
1.11 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84955 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57 days-71 days |
6 |
|
|
21.9 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84849 |
1602 |
SD |
food intake rate |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70 days-84 days |
6 |
|
|
24.6 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84859 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50 days-64 days |
6 |
|
|
18.5 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84868 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70 days-84 days |
6 |
|
|
21.8 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84871 |
1602 |
SD |
both kidneys wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
85 days-99 days |
6 |
|
|
0.88 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85217 |
1602 |
SD |
both lungs wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
71 days-85 days |
6 |
|
|
0.77 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85221 |
1602 |
SD |
both lungs wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
71 days-85 days |
6 |
|
|
0.81 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85224 |
1602 |
SD |
heart wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
71 days-85 days |
6 |
|
|
0.39 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85230 |
1602 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
64 days-78 days |
6 |
|
|
157.7 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84807 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
57 days-71 days |
6 |
|
|
151.6 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84816 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
71 days-85 days |
6 |
|
|
12.35 |
% |
0.24 |
0.59 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84964 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
85 days-99 days |
6 |
|
|
11.9 |
% |
0.18 |
0.45 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84967 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
71 days-85 days |
6 |
|
|
11.38 |
% |
0.37 |
0.9 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84970 |
1602 |
SD |
platelet count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
85 days-99 days |
6 |
|
|
1171.0 |
x 1000 cells/ul |
54.19 |
132.73 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84979 |
1602 |
SD |
platelet count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
71 days-85 days |
6 |
|
|
919.0 |
x 1000 cells/ul |
33.89 |
83.02 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84983 |
1602 |
SD |
platelet count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
71 days-85 days |
6 |
|
|
1025.83 |
x 1000 cells/ul |
20.16 |
49.39 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84984 |
1602 |
SD |
blood glucose level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
female |
71 days-85 days |
6 |
|
|
109.2 |
mg/dl |
11.08 |
27.13 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84994 |
1602 |
SD |
blood total cholesterol level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
male |
71 days-85 days |
6 |
|
|
92.8 |
mg/dl |
6.06 |
14.84 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85168 |
1602 |
SD |
blood total cholesterol level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
female |
85 days-99 days |
6 |
|
|
112.17 |
mg/dl |
3.51 |
8.59 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85177 |
1602 |
SD |
blood glucose level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
female |
71 days-85 days |
6 |
|
|
70.7 |
mg/dl |
4.78 |
11.71 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84993 |
1602 |
SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.6 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
2 |
days |
|
|
|
98789 |
2160 |
SD |
heart rate |
artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
419.0 |
beats/min |
21.0 |
51.44 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
720 |
min |
|
|
|
98795 |
2160 |
SD |
heart rate |
artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
405.0 |
beats/min |
10.0 |
24.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
2 |
days |
|
|
|
98797 |
2160 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
85.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
ACF |
360 |
min |
|
|
|
98806 |
2160 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
86.0 |
mmHg |
4.0 |
9.8 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98815 |
2160 |
SD |
creatinine clearance |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
glomerular filtration trait |
male |
0 days
| 7 |
|
|
0.7 |
ml/min |
0.26 |
0.69 |
automated serum creatinine analysis |
0.0 |
unx |
70 |
days |
|
|
|
98995 |
2179 |
SD |
percentage of study population developing anorectal malformation during a period of time |
in utero condition (for 7 days) and dibutyl phthalate (850 mg/kg/d) (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
anorectal integrity trait |
male |
1 days
| 43 |
|
|
39.5 |
% |
|
|
ex vivo light microscopy with histochemistry |
1.0 |
|
0 |
|
|
anorectal malformation incidence |
|
98733 |
2158 |
SD |
body weight |
in utero condition (for 7 days) and corn oil (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
body mass |
male |
1 days
| 0 |
|
|
6.34 |
g |
|
0.34 |
body weighing method |
1.0 |
|
0 |
|
|
|
|
98736 |
2158 |
SD |
anogenital distance to cube root of body weight ratio |
in utero condition (for 7 days) and dibutyl phthalate (850 mg/kg/d) (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
perineum length |
male |
1 days
| 43 |
|
|
1.48 |
null |
0.02 |
0.15 |
body measuring method |
1.0 |
|
0 |
|
|
mm/g^1/3 |
|
98737 |
2158 |
SD |
body weight |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then vehicle control condition (100 ul) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
body mass |
female |
0 days
| 13 |
|
|
283.6 |
g |
3.8 |
13.7 |
body weighing method |
0.0 |
unx |
97 |
days |
|
|
|
100632 |
2499 |
SD |
creatinine clearance |
controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) and enalapril (25 mg/l) (for 90 days) |
Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. |
glomerular filtration trait |
female |
0 days
| 12 |
|
|
0.58 |
ml/min |
0.05 |
0.17 |
serum creatinine analysis |
0.0 |
unx |
97 |
days |
|
|
|
100645 |
2499 |
SD |
duration of loss of righting reflex |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
balance trait |
female |
0 days
| 38 |
|
|
181.0 |
s |
9.08 |
56.0 |
visual assessment of in vivo video recording |
0.0 |
|
0 |
|
|
time to rigthing reflex post anesthesia |
|
98200 |
2040 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
58.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
360 |
min |
|
|
|
98831 |
2160 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
62.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
720 |
min |
|
|
|
98833 |
2160 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
64.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98839 |
2160 |
SD |
ejection fraction |
sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
cardiac output trait |
male |
0 days
| 6 |
|
|
65.0 |
% |
2.0 |
4.9 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
360 |
min |
|
|
|
98879 |
2160 |
SD |
ejection fraction |
artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
cardiac output trait |
male |
0 days
| 6 |
|
|
75.0 |
% |
3.0 |
7.35 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
2 |
days |
|
|
|
98882 |
2160 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 8 |
|
|
15.6 |
null |
3.61 |
10.2 |
elevated plus maze apparatus method |
300.0 |
sham coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98216 |
2040 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (140 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 14 |
|
|
22.8 |
null |
2.97 |
11.1 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98217 |
2040 |
SD |
serum creatinine level |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
blood creatinine amount |
male |
0 days
| 7 |
|
|
2.5 |
mg/dl |
0.5 |
1.32 |
automated serum creatinine analysis |
0.0 |
unx |
70 |
days |
|
|
|
98992 |
2179 |
SD |
mean arterial blood pressure |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
arterial blood pressure trait |
male |
90 days
| 9 |
|
|
118.0 |
mmHg |
5.0 |
15.0 |
vascular fluid filled catheter |
0.0 |
|
0 |
|
|
|
|
101222 |
2582 |
SD |
glomerular filtration rate to body weight ratio |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
glomerular filtration trait |
male |
420 days-450 days |
9 |
|
|
0.28 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
101227 |
2582 |
SD |
urine protein excretion rate |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
total urine protein amount |
male |
420 days-450 days |
9 |
|
|
51.0 |
mg/d |
13.0 |
39.0 |
urine protein analysis |
0.0 |
|
0 |
|
|
|
|
101235 |
2582 |
SD |
systolic blood pressure |
unilateral nephrectomy (for 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
201.0 |
mmHg |
6.72 |
19.0 |
tail cuff plethysmography |
0.0 |
unx |
14 |
days |
|
|
|
101615 |
2602 |
SD |
systolic blood pressure |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
208.0 |
mmHg |
6.01 |
17.0 |
tail cuff plethysmography |
0.0 |
unx |
28 |
days |
|
|
|
101617 |
2602 |
SD |
systolic blood pressure |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
190.0 |
mmHg |
9.9 |
28.0 |
tail cuff plethysmography |
0.0 |
unx |
28 |
days |
|
|
|
101618 |
2602 |
SD |
heart wet weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
0 days
| 8 |
|
|
1.33 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101619 |
2602 |
SD |
heart wet weight |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
0 days
| 8 |
|
|
1.21 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101620 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 8 |
|
|
243.0 |
mg/d |
26.16 |
74.0 |
urine protein analysis |
0.0 |
unx |
28 |
days |
|
|
|
101624 |
2602 |
SD |
plasma potassium level |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood potassium amount |
male |
0 days
| 7 |
|
|
6.2 |
mmol/l |
0.15 |
0.4 |
ex vivo blood analysis |
0.0 |
unx |
28 |
days |
|
|
|
101597 |
2602 |
SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 7 |
|
|
57.0 |
mg |
1.51 |
4.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101601 |
2602 |
SD |
body weight |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 6 |
|
|
336.0 |
g |
6.53 |
16.0 |
body weighing method |
0.0 |
sham unx |
13 |
days |
|
|
|
101535 |
2602 |
SD |
body weight |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 6 |
|
|
347.0 |
g |
7.35 |
18.0 |
body weighing method |
0.0 |
sham unx |
28 |
days |
|
|
|
101571 |
2602 |
SD |
body weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 7 |
|
|
307.0 |
g |
36.66 |
25.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
|
|
101573 |
2602 |
SD |
change in body weight |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 6 |
|
|
99.0 |
g |
6.53 |
16.0 |
body weighing method |
0.0 |
sham unx |
28 |
days |
|
change from surgery weight |
|
101575 |
2602 |
SD |
change in body weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 6 |
|
|
106.0 |
g |
10.61 |
26.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
change from surgery weight |
|
101578 |
2602 |
SD |
heart wet weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
0 days
| 7 |
|
|
1.33 |
g |
0.07 |
0.19 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101588 |
2602 |
SD |
heart wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
0 days
| 6 |
|
|
1.28 |
g |
0.05 |
0.12 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101590 |
2602 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
0.06 |
null |
0.01 |
0.03 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
0 |
|
|
protein/creatinine |
|
98962 |
2179 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
7.2 |
null |
0.7 |
1.85 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
56 |
days |
|
|
|
98970 |
2179 |
SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
|
|
1.94 |
g |
0.02 |
0.07 |
post excision weight measurement |
0.0 |
stz |
154 |
days |
|
|
|
99893 |
2358 |
SD |
blood glucose level |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
|
|
343.0 |
mg/dl |
18.38 |
52.0 |
blood glucose analysis |
0.0 |
stz |
154 |
days |
|
|
|
99897 |
2358 |
SD |
blood glucose level |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
|
|
106.0 |
mg/dl |
4.6 |
13.0 |
blood glucose analysis |
0.0 |
|
0 |
|
|
|
|
99898 |
2358 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 16 |
|
|
21.5 |
s |
3.55 |
14.2 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time to platform |
|
98242 |
2040 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 11 |
|
|
1168.0 |
cm |
109.45 |
363.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
|
|
98249 |
2040 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 9 |
|
|
79.3 |
s |
16.0 |
48.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
time in open arms |
|
98260 |
2040 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 9 |
|
|
51.9 |
s |
6.57 |
19.7 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
time in open arms |
|
98261 |
2040 |
SD |
body weight |
artificial aortocaval fistula (for 5 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
body mass |
male |
0 days
| 6 |
|
|
281.0 |
g |
4.0 |
9.8 |
body weighing method |
1.0 |
ACF |
5 |
days |
|
|
|
98775 |
2160 |
SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
0 days
| 6 |
g/g*103 |
|
3.3 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
360 |
min |
|
|
|
98777 |
2160 |
SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
0 days
| 6 |
g/g*103 |
|
3.5 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
720 |
min |
|
|
|
98779 |
2160 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 10 |
|
|
35.3 |
null |
2.81 |
8.9 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98221 |
2040 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
7.4 |
mm |
0.3 |
0.73 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
360 |
min |
|
|
|
98842 |
2160 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
8.1 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
2 |
days |
|
|
|
98846 |
2160 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-systolic diameter |
male |
0 days
| 6 |
|
|
3.8 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
720 |
min |
|
|
|
98853 |
2160 |
SD |
heart left ventricle end-diastolic posterior wall thickness |
sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle posterior wall thickness |
male |
0 days
| 6 |
|
|
1.6 |
mm |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
2 |
days |
|
|
|
98863 |
2160 |
SD |
body weight |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 9 |
|
|
300.0 |
g |
5.0 |
15.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
|
|
98930 |
2179 |
SD |
body weight |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 7 |
|
|
296.0 |
g |
11.0 |
29.1 |
body weighing method |
0.0 |
unx |
28 |
days |
|
|
|
98931 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 7 |
|
|
161.0 |
mmHg |
7.0 |
18.52 |
tail cuff plethysmography |
0.0 |
unx |
56 |
days |
|
|
|
98944 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 7 |
|
|
137.0 |
mmHg |
3.0 |
7.94 |
tail cuff plethysmography |
0.0 |
unx |
70 |
days |
|
|
|
98949 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
30.0 |
mg/d |
3.0 |
7.94 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
28 |
days |
|
|
|
98955 |
2179 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (140 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 14 |
|
|
58.7 |
s |
10.21 |
38.2 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time in open arms |
|
98223 |
2040 |
SD |
heart weight |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
175 days
| 10 |
|
|
2.23 |
g |
0.11 |
0.35 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
|
|
99198 |
2278 |
SD |
heart right ventricle weight to body weight ratio |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart right ventricle mass |
male |
175 days
| 10 |
|
|
0.5 |
mg/g |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
|
|
99209 |
2278 |
SD |
lung weight |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
lung mass |
male |
98 days
| 8 |
|
|
1.84 |
g |
0.08 |
0.23 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
|
|
99212 |
2278 |
SD |
lung weight |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
lung mass |
male |
175 days
| 10 |
|
|
1.97 |
g |
0.06 |
0.19 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
|
|
99213 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
5.0 |
mmHg |
1.0 |
3.16 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
105 |
days |
|
|
|
99225 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
8031.0 |
mmHg/s |
440.0 |
1244.51 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99227 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
7529.0 |
mmHg/s |
445.0 |
1407.21 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
105 |
days |
|
|
|
99229 |
2278 |
SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
|
43.0 |
% |
1.0 |
2.83 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99370 |
2278 |
SD |
ejection fraction |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
72 days
| 5 |
|
|
76.0 |
% |
5.0 |
11.18 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99372 |
2278 |
SD |
blood glucose level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood glucose amount |
male |
140 days
| 6 |
|
|
134.7 |
mg/dl |
5.9 |
14.45 |
blood glucose analysis |
0.0 |
unx |
84 |
days |
|
|
|
100120 |
2419 |
SD |
creatinine clearance |
controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
glomerular filtration trait |
male |
140 days
| 6 |
|
|
5.2 |
ml/min |
0.4 |
0.98 |
urine creatinine analysis |
0.0 |
x |
0 |
days |
|
|
|
100134 |
2419 |
SD |
creatinine clearance |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
glomerular filtration trait |
male |
140 days
| 8 |
|
|
2.3 |
ml/min |
0.3 |
0.85 |
urine creatinine analysis |
0.0 |
unx |
84 |
days |
|
|
|
100138 |
2419 |
SD |
body weight |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
body mass |
male |
189 days
| 10 |
|
|
568.3 |
g |
34.1 |
107.83 |
body weighing method |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101077 |
2564 |
SD |
body weight |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
body mass |
male |
189 days
| 6 |
|
|
532.2 |
g |
20.4 |
49.97 |
body weighing method |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101078 |
2564 |
SD |
heart weight to body weight ratio |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart mass |
male |
77 days
| 6 |
|
|
2.92 |
g/kg |
0.04 |
0.1 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101084 |
2564 |
SD |
heart weight to body weight ratio |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart mass |
male |
189 days
| 10 |
|
|
2.78 |
g/kg |
0.07 |
0.22 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101085 |
2564 |
SD |
heart left ventricle weight |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle mass |
male |
189 days
| 10 |
|
|
0.87 |
g |
0.03 |
0.09 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101093 |
2564 |
SD |
heart right ventricle weight to body weight ratio |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right ventricle mass |
male |
77 days
| 6 |
|
|
0.62 |
mg/g |
0.01 |
0.02 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101103 |
2564 |
SD |
heart right ventricle weight to body weight ratio |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right ventricle mass |
male |
189 days
| 6 |
|
|
0.51 |
mg/g |
0.01 |
0.02 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101106 |
2564 |
SD |
left atrium weight |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left atrium mass |
male |
77 days
| 6 |
|
|
0.03 |
g |
0.0 |
0.0 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101108 |
2564 |
SD |
right atrium weight |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right atrium mass |
male |
77 days
| 6 |
|
|
0.04 |
g |
0.0 |
0.0 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101115 |
2564 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
|
7.0 |
mm |
0.2 |
0.57 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99235 |
2278 |
SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 8 |
|
|
4.3 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99239 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
lvedd/pw |
|
5.9 |
null |
0.3 |
0.95 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
heart left ventricle end-diastolic dimeter to posterior wall thickness ratio |
|
99245 |
2278 |
SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
72.0 |
g/cm2 |
7.0 |
22.14 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
|
|
99253 |
2278 |
SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
80.0 |
g/cm2 |
6.0 |
18.97 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
|
|
99254 |
2278 |
SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
|
38.0 |
% |
2.0 |
5.66 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99256 |
2278 |
SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
|
|
34.0 |
% |
2.0 |
6.32 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
|
|
99258 |
2278 |
SD |
heart left ventricle interstitial angiotensin II level during a period of time |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial angiotensin II amount |
male |
175 days
| 8 |
|
|
1.6 |
pg/hr |
0.2 |
0.57 |
radioimmunoassay |
0.0 |
sham ACF |
105 |
days |
|
heart left ventricle interstitial angiotensin II level during a period of time |
|
99261 |
2278 |
SD |
heart left ventricle interstitial angiotensin II level during a period of time |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial angiotensin II amount |
male |
175 days
| 10 |
|
|
1.9 |
pg/hr |
0.1 |
0.32 |
radioimmunoassay |
0.0 |
ACF |
105 |
days |
|
heart left ventricle interstitial angiotensin II level during a period of time |
|
99262 |
2278 |
SD |
plasma bradykinin level |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood bradykinin amount |
male |
98 days
| 8 |
|
|
10.0 |
pg/ml |
1.0 |
2.83 |
radioimmunoassay |
0.0 |
sham ACF |
28 |
days |
|
pl bk |
|
99279 |
2278 |
SD |
plasma epinephrine level |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood epinephrine amount |
male |
175 days
| 8 |
|
|
75.0 |
pg/ml |
6.0 |
16.97 |
enzyme linked immunosorbent assay |
0.0 |
sham ACF |
105 |
days |
|
|
|
99289 |
2278 |
SD |
heart rate |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
98 days
| 7 |
|
|
312.0 |
beats/min |
5.0 |
13.23 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99297 |
2278 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
72 days
| 5 |
|
|
89.0 |
mmHg |
3.0 |
6.71 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99300 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
4.0 |
mmHg |
1.0 |
2.65 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99313 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
7931.0 |
mmHg/s |
415.0 |
1097.99 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99329 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
-8797.0 |
mmHg/s |
411.0 |
919.02 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99332 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
|
8.2 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99340 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
|
8.0 |
mm |
0.1 |
0.22 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99342 |
2278 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 8 |
|
|
5.9 |
mm |
0.2 |
0.57 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99354 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
lvedd/pw |
|
4.2 |
null |
0.2 |
0.53 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
99359 |
2278 |
SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
|
41.0 |
% |
2.0 |
4.47 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
ledd/pw |
|
99363 |
2278 |
SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
|
48.0 |
% |
5.0 |
11.18 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
ledd/pw |
|
99364 |
2278 |
SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
4.0 |
g/cm2 |
1.0 |
2.24 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
lved-ws |
|
99387 |
2278 |
SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
65.0 |
g/cm2 |
5.0 |
13.23 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99399 |
2278 |
SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
62.0 |
g/cm2 |
6.0 |
16.97 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99402 |
2278 |
SD |
ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial collagen amount |
male |
72 days
| 5 |
|
|
4.0 |
% |
0.3 |
0.67 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
sham ACF |
2 |
days |
|
|
|
99405 |
2278 |
SD |
ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial collagen amount |
male |
98 days
| 7 |
|
|
2.4 |
% |
0.1 |
0.26 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
sham ACF |
28 |
days |
|
|
|
99408 |
2278 |
SD |
renal filtration fraction |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.3 |
null |
0.01 |
0.02 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
GFR by inulin method |
|
|
99913 |
2358 |
SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
|
|
2.14 |
g |
0.04 |
0.12 |
post excision weight measurement |
0.0 |
stz |
224 |
days |
|
|
|
99918 |
2358 |
SD |
left kidney wet weight |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
0 days
| 8 |
|
|
1.83 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
99919 |
2358 |
SD |
systolic blood pressure |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
126.0 |
mmHg |
1.06 |
3.0 |
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
99925 |
2358 |
SD |
glomerular filtration rate to body weight ratio |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.69 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
|
0 |
|
|
|
|
99928 |
2358 |
SD |
effective renal plasma flow |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney plasma flow trait |
male |
0 days
| 8 |
|
|
2.27 |
ml/min/100g |
0.06 |
0.18 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
stz |
224 |
days |
|
|
|
99930 |
2358 |
SD |
renal filtration fraction |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.29 |
null |
0.0 |
0.01 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
GFR by inulin method |
|
|
99934 |
2358 |
SD |
both kidneys wet weight as percentage of body weight |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
kidney mass |
male |
120 days
| 3 |
|
|
0.55 |
% |
0.03 |
0.06 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
100194 |
2439 |
SD |
plasma angiotensin I level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood angiotensin I amount |
male |
60 days
| 3 |
|
|
300.0 |
pg/ml |
103.92 |
180.0 |
enzyme immunoassay |
0.0 |
|
0 |
|
|
|
|
100219 |
2439 |
SD |
plasma angiotensin I level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood angiotensin I amount |
male |
180 days
| 3 |
|
|
180.0 |
pg/ml |
23.09 |
40.0 |
enzyme immunoassay |
0.0 |
|
0 |
|
|
|
|
100223 |
2439 |
SD |
serum testosterone level |
in utero condition (for 7 days) and dibutyl phthalate (850 mg/kg/d) (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
blood testosterone amount |
male |
1 days
| 6 |
|
|
0.4 |
ng/ml |
0.05 |
0.13 |
radioimmunoassay |
1.0 |
|
0 |
|
|
|
|
98731 |
2158 |
SD |
retinal uptake index of verapamil |
tritiated verapamil (10 uCi) (for 0 hours) and vinblastine (1 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
327.0 |
% |
35.0 |
60.62 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
verapamil uptake index |
|
106121 |
3028 |
SD |
brain uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
13.2 |
% |
3.2 |
5.54 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106152 |
3028 |
SD |
brain uptake index of digoxin |
tritiated digoxin (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
0.96 |
% |
0.05 |
0.08 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
digoxin uptake index |
|
106155 |
3028 |
SD |
brain uptake index of verapamil |
tritiated verapamil (10 uCi) (for 0 hours) and vinblastine (1 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
42.5 |
% |
4.8 |
8.31 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
verapamil uptake index |
|
106157 |
3028 |
SD |
serum interleukin-9 level |
vehicle control condition then acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood interleukin-9 amount |
not specified |
0 days
| 4 |
|
|
0.1 |
ug/l |
0.01 |
0.01 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105415 |
3015 |
SD |
serum interleukin-9 level |
acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood interleukin-9 amount |
not specified |
0 days
| 12 |
|
|
0.08 |
ug/l |
0.0 |
0.01 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105416 |
3015 |
SD |
intestine trypsin level |
vehicle control condition then acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
intestine trypsin amount |
not specified |
0 days
| 4 |
|
|
0.17 |
ug/l |
0.01 |
0.01 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105419 |
3015 |
SD |
intestine trypsin level |
acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
intestine trypsin amount |
not specified |
0 days
| 12 |
|
|
0.23 |
ug/l |
0.01 |
0.02 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105421 |
3015 |
SD |
verapamil equilibrated distribution volume in brain |
tritiated verapamil (10 uCi) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
0.54 |
ml/g |
0.01 |
0.02 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
|
|
106110 |
3028 |
SD |
timed urine volume |
control condition |
Eisenberger U, etal., Ren Physiol Biochem. 1995 Mar-Apr;18(2):89-96. doi: 10.1159/000173904. |
urine output |
female |
96 days-121 days |
7 |
|
|
17.1 |
ml/d |
2.42 |
6.4 |
metabolic cage urine volume measurement method |
0.0 |
|
0 |
|
|
|
|
110180 |
3166 |
SD |
timed urine volume |
doxorubicin (5 mg/kg) (between 6 and 7 days) |
Eisenberger U, etal., Ren Physiol Biochem. 1995 Mar-Apr;18(2):89-96. doi: 10.1159/000173904. |
urine output |
female |
96 days-121 days |
7 |
|
|
9.3 |
ml/d |
0.6 |
1.6 |
metabolic cage urine volume measurement method |
0.0 |
|
0 |
|
|
|
|
110182 |
3166 |
SD |
creatinine clearance |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
glomerular filtration trait |
male |
180 days
| 5 |
|
|
0.0 |
ml/min |
0.0 |
0.0 |
urine creatinine analysis |
0.0 |
|
0 |
|
|
|
|
100214 |
2439 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64 days-78 days |
6 |
|
|
34.8 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84838 |
1602 |
SD |
blood hemoglobin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
71 days-85 days |
6 |
|
|
13.8 |
g/dl |
0.16 |
0.38 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84939 |
1602 |
SD |
blood glucose level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
male |
71 days-85 days |
6 |
|
|
127.0 |
mg/dl |
8.82 |
21.6 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84989 |
1602 |
SD |
blood glucose level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
male |
85 days-99 days |
6 |
|
|
62.11 |
mg/dl |
13.41 |
32.84 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84992 |
1602 |
SD |
plasma total protein level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
male |
71 days-85 days |
6 |
|
|
62.0 |
mg/ml |
1.27 |
3.1 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85013 |
1602 |
SD |
blood urea nitrogen level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
male |
85 days-99 days |
6 |
|
|
10.97 |
mg/dl |
2.32 |
5.68 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85040 |
1602 |
SD |
blood creatinine level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood creatinine amount |
male |
85 days-99 days |
6 |
|
|
0.3 |
mg/dl |
0.07 |
0.16 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85064 |
1602 |
SD |
blood alkaline phosphatase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
female |
71 days-85 days |
6 |
|
|
423.17 |
U/l |
20.15 |
49.35 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85104 |
1602 |
SD |
blood triglyceride level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
male |
71 days-85 days |
6 |
|
|
92.3 |
mg/dl |
21.39 |
52.39 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85182 |
1602 |
SD |
blood triglyceride level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
female |
85 days-99 days |
6 |
|
|
32.67 |
mg/dl |
2.35 |
5.75 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85189 |
1602 |
SD |
spleen wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
71 days-85 days |
6 |
|
|
0.29 |
g |
0.08 |
0.19 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85243 |
1602 |
SD |
brain wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
85 days-99 days |
6 |
|
|
1.09 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85265 |
1602 |
SD |
adrenal gland wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
71 days-85 days |
6 |
|
|
0.04 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85273 |
1602 |
SD |
testis wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
85 days-99 days |
6 |
|
|
1.01 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85283 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
57 days-71 days |
6 |
|
|
228.0 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84784 |
1602 |
SD |
blood hemoglobin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
71 days-85 days |
6 |
|
|
12.98 |
g/dl |
0.2 |
0.48 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84948 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
71 days-85 days |
6 |
|
|
11.13 |
% |
0.35 |
0.85 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84972 |
1602 |
SD |
platelet count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
71 days-85 days |
6 |
|
|
855.83 |
x 1000 cells/ul |
38.39 |
94.03 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84982 |
1602 |
SD |
blood phosphate level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
female |
71 days-85 days |
6 |
|
|
6.53 |
mg/dl |
0.39 |
0.96 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85164 |
1602 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
74.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
ACF |
5 |
days |
|
|
|
98812 |
2160 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 2 days) then metoprolol (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
71.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98816 |
2160 |
SD |
verapamil apparent influx permeability clearance in retina |
tritiated verapamil (10 uCi) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
0.82 |
ml/min/g |
0.12 |
0.2 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
|
|
106102 |
3028 |
SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
7.0 |
g/cm2 |
1.0 |
3.16 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
|
|
99249 |
2278 |
SD |
blood calcium level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
female |
71 days-85 days |
6 |
|
|
10.05 |
mg/dl |
0.08 |
0.2 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85150 |
1602 |
SD |
blood total cholesterol level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
female |
85 days-99 days |
6 |
|
|
109.17 |
mg/dl |
4.94 |
12.09 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85178 |
1602 |
SD |
body weight |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 11 |
|
|
277.0 |
g |
8.14 |
27.0 |
body weighing method |
0.0 |
unx |
13 |
days |
|
|
|
101536 |
2602 |
SD |
body weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 7 |
|
|
309.0 |
g |
18.9 |
50.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
|
|
101572 |
2602 |
SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 7 |
|
|
1.47 |
g |
0.07 |
0.18 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
remnant kidney |
|
101581 |
2602 |
SD |
systolic blood pressure |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 6 |
undefined |
|
186.0 |
mmHg |
10.61 |
26.0 |
tail cuff plethysmography |
0.0 |
unx |
28 |
days |
|
|
|
101586 |
2602 |
SD |
food intake rate |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
eating behavior trait |
male |
0 days
| 8 |
|
|
19.0 |
g/d |
2.83 |
8.0 |
unspecified method |
0.0 |
unx |
28 |
days |
|
|
|
101611 |
2602 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
4.5 |
null |
0.5 |
1.22 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
720 |
min |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
98869 |
2160 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
4.6 |
null |
0.2 |
0.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
2 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
98871 |
2160 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
4.4 |
null |
0.4 |
0.98 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
5 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
98873 |
2160 |
SD |
ejection fraction |
sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
cardiac output trait |
male |
0 days
| 6 |
|
|
63.0 |
% |
3.0 |
7.35 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
720 |
min |
|
|
|
98881 |
2160 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 17 |
|
|
16.7 |
s |
1.96 |
8.1 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
time to platform |
|
98266 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (500 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (615 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 9 |
|
|
15.7 |
s |
2.67 |
8.0 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
time in platform |
|
98275 |
2040 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
64 days-78 days |
6 |
|
|
157.9 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84812 |
1602 |
SD |
glomerular filtration rate to body weight ratio |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.67 |
ml/min/100g |
0.02 |
0.06 |
inulin analysis by thiourea-resorcinol assay |
0.0 |
|
0 |
|
|
|
|
99904 |
2358 |
SD |
body weight |
in utero condition (for 7 days) and dibutyl phthalate (850 mg/kg/d) (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
body mass |
male |
1 days
| 43 |
|
|
4.9 |
g |
0.06 |
0.39 |
body weighing method |
1.0 |
|
0 |
|
|
|
|
98735 |
2158 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 21 |
|
|
1241.0 |
cm |
71.14 |
326.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98212 |
2040 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 16 |
|
|
1263.0 |
cm |
92.75 |
371.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
|
|
98214 |
2040 |
SD |
heart left ventricle end-diastolic posterior wall thickness |
artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle posterior wall thickness |
male |
0 days
| 6 |
|
|
1.5 |
mm |
0.3 |
0.73 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
5 |
days |
|
|
|
98864 |
2160 |
SD |
maximum rate of positive change in left ventricular blood pressure |
artificial aortocaval fistula (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
8259.0 |
mmHg/s |
325.0 |
796.08 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98886 |
2160 |
SD |
right atrium weight |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right atrium mass |
male |
189 days
| 6 |
|
|
0.04 |
g |
0.0 |
0.01 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101118 |
2564 |
SD |
heart septum weight |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart septum morphology trait |
male |
189 days
| 10 |
|
|
0.33 |
g |
0.01 |
0.03 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
septum |
|
101125 |
2564 |
SD |
red blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
85 days-99 days |
6 |
|
|
8.77 |
x 10E6 cells/ul |
0.2 |
0.49 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84913 |
1602 |
SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
6.0 |
g/cm2 |
1.0 |
2.24 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
|
|
99389 |
2278 |
SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
16.0 |
g/cm2 |
2.0 |
5.66 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99394 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
6.0 |
mmHg |
1.0 |
2.24 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99307 |
2278 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
55.0 |
mmHg |
3.0 |
6.71 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99315 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
-7474.0 |
mmHg/s |
152.0 |
339.88 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99331 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
|
6.9 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
|
|
99339 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
lvedd/pw |
|
4.6 |
null |
0.2 |
0.45 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
99355 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
-7197.0 |
mmHg/s |
303.0 |
742.2 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98891 |
2160 |
SD |
maximum rate of negative change in left ventricular blood pressure |
sham surgical control condition (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
-7212.0 |
mmHg/s |
416.0 |
1018.99 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98893 |
2160 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
3.5 |
null |
0.5 |
1.32 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
28 |
days |
|
|
|
98965 |
2179 |
SD |
urine protein level to urine creatinine level ratio |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
4.8 |
null |
0.5 |
1.32 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
28 |
days |
|
|
|
98967 |
2179 |
SD |
blood glucose level |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
|
|
334.0 |
mg/dl |
19.8 |
56.0 |
blood glucose analysis |
0.0 |
stz |
154 |
days |
|
|
|
99896 |
2358 |
SD |
systolic blood pressure |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
152.0 |
mmHg |
1.06 |
3.0 |
tail cuff plethysmography |
0.0 |
stz |
154 |
days |
|
|
|
99899 |
2358 |
SD |
left kidney wet weight |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
kidney mass |
male |
420 days-450 days |
9 |
|
|
1.8 |
g |
0.12 |
0.36 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
101217 |
2582 |
SD |
systolic blood pressure |
controlled losartan content drinking water (5 mg/kg/d) (for 10 days) |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
130 days
| 1 |
mean of 3 samples - 1 per minute |
serial mean |
116.0 |
mmHg |
|
|
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100190 |
2439 |
SD |
blood triglyceride level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
male |
71 days-85 days |
6 |
|
|
52.3 |
mg/dl |
3.15 |
7.71 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85179 |
1602 |
SD |
blood triglyceride level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
female |
71 days-85 days |
6 |
|
|
27.7 |
mg/dl |
2.83 |
6.92 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85186 |
1602 |
SD |
liver wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
71 days-85 days |
6 |
|
|
4.31 |
g |
0.14 |
0.35 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85192 |
1602 |
SD |
liver wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
71 days-85 days |
6 |
|
|
4.06 |
g |
0.16 |
0.39 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85201 |
1602 |
SD |
heart wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
85 days-99 days |
6 |
|
|
0.44 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85240 |
1602 |
SD |
spleen wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
71 days-85 days |
6 |
|
|
0.24 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85248 |
1602 |
SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
71 days-85 days |
6 |
|
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85266 |
1602 |
SD |
adrenal gland wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
85 days-99 days |
6 |
|
|
0.04 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85277 |
1602 |
SD |
testis wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
71 days-85 days |
6 |
|
|
1.17 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85278 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
64 days-78 days |
6 |
|
|
242.6 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84763 |
1602 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
57 days-71 days |
6 |
|
|
227.7 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84767 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
64 days-78 days |
6 |
|
|
246.8 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84778 |
1602 |
SD |
body weight |
acetaminophen (250 mg/kg) (for 1 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
42 days-56 days |
6 |
|
|
136.3 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84799 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
70 days-84 days |
6 |
|
|
164.5 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84823 |
1602 |
SD |
food intake rate |
acetaminophen (250 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64 days-78 days |
6 |
|
|
23.5 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84854 |
1602 |
SD |
food intake rate |
acetaminophen (500 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64 days-78 days |
6 |
|
|
21.6 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84858 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57 days-71 days |
6 |
|
|
25.2 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84861 |
1602 |
SD |
blood hemoglobin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
71 days-85 days |
6 |
|
|
14.02 |
g/dl |
0.28 |
0.69 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84940 |
1602 |
SD |
blood hemoglobin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
85 days-99 days |
6 |
|
|
12.38 |
g/dl |
0.36 |
0.88 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84950 |
1602 |
SD |
blood urea nitrogen level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
male |
71 days-85 days |
6 |
|
|
16.0 |
mg/dl |
0.93 |
2.28 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85035 |
1602 |
SD |
blood urea nitrogen level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
female |
71 days-85 days |
6 |
|
|
15.5 |
mg/dl |
0.76 |
1.87 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85043 |
1602 |
SD |
blood urea nitrogen level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
female |
71 days-85 days |
6 |
|
|
38.2 |
mg/dl |
3.37 |
8.26 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85044 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
male |
71 days-85 days |
6 |
|
|
0.8 |
null |
0.02 |
0.06 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85047 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
71 days-85 days |
6 |
|
|
1.1 |
null |
0.03 |
0.08 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85054 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
85 days-99 days |
6 |
|
|
0.93 |
null |
0.06 |
0.15 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85057 |
1602 |
SD |
blood alanine aminotransferase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
male |
71 days-85 days |
6 |
|
|
46.7 |
U/l |
2.05 |
5.01 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85083 |
1602 |
SD |
blood alanine aminotransferase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
female |
71 days-85 days |
6 |
|
|
116.5 |
U/l |
13.45 |
32.94 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85094 |
1602 |
SD |
blood alkaline phosphatase activity level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
male |
71 days-85 days |
6 |
|
|
327.2 |
U/l |
66.05 |
161.8 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85097 |
1602 |
SD |
blood alkaline phosphatase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
male |
85 days-99 days |
6 |
|
|
245.33 |
U/l |
54.57 |
133.66 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85100 |
1602 |
SD |
blood bilirubin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
male |
71 days-85 days |
6 |
|
|
0.3 |
mg/dl |
0.04 |
0.09 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85107 |
1602 |
SD |
blood potassium level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
female |
71 days-85 days |
6 |
|
|
4.6 |
mmol/l |
0.1 |
0.25 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85138 |
1602 |
SD |
blood potassium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
female |
71 days-85 days |
6 |
|
|
2.27 |
mmol/l |
0.38 |
0.92 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85140 |
1602 |
SD |
blood phosphate level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
female |
71 days-85 days |
6 |
|
|
5.88 |
mg/dl |
0.16 |
0.4 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85162 |
1602 |
SD |
blood triglyceride level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
male |
71 days-85 days |
6 |
|
|
141.2 |
mg/dl |
39.8 |
97.48 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85180 |
1602 |
SD |
blood triglyceride level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
male |
85 days-99 days |
6 |
|
|
65.45 |
mg/dl |
8.04 |
19.69 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85183 |
1602 |
SD |
liver wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
85 days-99 days |
6 |
|
|
3.56 |
g |
0.05 |
0.12 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85196 |
1602 |
SD |
blood calcium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood calcium amount |
female |
85 days-99 days |
6 |
|
|
10.23 |
mg/dl |
0.13 |
0.32 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85153 |
1602 |
SD |
plasma total protein level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood total protein amount |
male |
85 days-99 days |
6 |
|
|
46.0 |
mg/ml |
10.74 |
26.3 |
automated plasma analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85016 |
1602 |
SD |
blood globulin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
male |
71 days-85 days |
6 |
|
|
2.9 |
g/dl |
0.04 |
0.1 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85025 |
1602 |
SD |
blood globulin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood globulin amount |
male |
85 days-99 days |
6 |
|
|
2.12 |
g/dl |
0.5 |
1.23 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85028 |
1602 |
SD |
blood aspartate aminotransferase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood aspartate transaminase amount |
male |
85 days-99 days |
6 |
|
|
145.57 |
U/l |
24.67 |
60.42 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85075 |
1602 |
SD |
blood alkaline phosphatase activity level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
male |
71 days-85 days |
6 |
|
|
469.0 |
U/l |
85.91 |
210.44 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85096 |
1602 |
SD |
blood alkaline phosphatase activity level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
female |
71 days-85 days |
6 |
|
|
416.5 |
U/l |
68.13 |
166.88 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85103 |
1602 |
SD |
blood bilirubin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood bilirubin amount |
female |
85 days-99 days |
6 |
|
|
0.63 |
mg/dl |
0.04 |
0.11 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85118 |
1602 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57 days-71 days |
6 |
|
|
35.0 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84825 |
1602 |
SD |
food intake rate |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70 days-84 days |
6 |
|
|
32.4 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84831 |
1602 |
SD |
red blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
85 days-99 days |
6 |
|
|
8.8 |
x 10E6 cells/ul |
0.13 |
0.31 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84898 |
1602 |
SD |
blood differential white blood cell count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
71 days-85 days |
6 |
|
|
8.81 |
x 1000 cells/ul |
1.05 |
2.56 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84904 |
1602 |
SD |
blood differential white blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
85 days-99 days |
6 |
|
|
8.24 |
x 1000 cells/ul |
0.77 |
1.88 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84906 |
1602 |
SD |
red blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
85 days-99 days |
6 |
|
|
8.97 |
x 10E6 cells/ul |
0.2 |
0.49 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84914 |
1602 |
SD |
uterus wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
85 days-99 days |
6 |
|
|
0.27 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85289 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57 days-71 days |
6 |
|
|
34.9 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84845 |
1602 |
SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64 days-78 days |
6 |
|
|
39.4 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84846 |
1602 |
SD |
both kidneys wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
71 days-85 days |
6 |
|
|
0.92 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85215 |
1602 |
SD |
both lungs wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
71 days-85 days |
6 |
|
|
0.68 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85220 |
1602 |
SD |
both lungs wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
85 days-99 days |
6 |
|
|
0.64 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85223 |
1602 |
SD |
both lungs wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
71 days-85 days |
6 |
|
|
0.76 |
g |
0.02 |
0.06 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85225 |
1602 |
SD |
both lungs wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
85 days-99 days |
6 |
|
|
0.74 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85229 |
1602 |
SD |
body weight |
acetaminophen (500 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
57 days-71 days |
6 |
|
|
229.6 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84772 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
70 days-84 days |
6 |
|
|
166.7 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84813 |
1602 |
SD |
blood differential white blood cell count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
71 days-85 days |
6 |
|
|
7.68 |
x 1000 cells/ul |
1.1 |
2.69 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84888 |
1602 |
SD |
blood hemoglobin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
71 days-85 days |
6 |
|
|
13.68 |
g/dl |
0.17 |
0.41 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84941 |
1602 |
SD |
blood hemoglobin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
85 days-99 days |
6 |
|
|
13.75 |
g/dl |
0.26 |
0.64 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84944 |
1602 |
SD |
red blood cell distribution width-coefficient of variation |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
85 days-99 days |
6 |
|
|
11.32 |
% |
0.24 |
0.59 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84973 |
1602 |
SD |
platelet count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
71 days-85 days |
6 |
|
|
1148.83 |
x 1000 cells/ul |
114.06 |
279.4 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84976 |
1602 |
SD |
platelet count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
85 days-99 days |
6 |
|
|
931.0 |
x 1000 cells/ul |
34.34 |
84.12 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84986 |
1602 |
SD |
blood glucose level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood glucose amount |
female |
71 days-85 days |
6 |
|
|
116.2 |
mg/dl |
9.03 |
22.13 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
84995 |
1602 |
SD |
blood albumin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
85 days-99 days |
6 |
|
|
3.6 |
g/dl |
0.06 |
0.14 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85009 |
1602 |
SD |
blood total cholesterol level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood cholesterol amount |
male |
71 days-85 days |
6 |
|
|
87.8 |
mg/dl |
3.31 |
8.11 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85169 |
1602 |
SD |
heart rate |
artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
395.0 |
beats/min |
5.0 |
12.25 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
5 |
days |
|
|
|
98799 |
2160 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
90.0 |
mmHg |
5.0 |
12.25 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
720 |
min |
|
|
|
98809 |
2160 |
SD |
heart rate |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
98 days
| 8 |
|
|
260.0 |
beats/min |
12.0 |
33.94 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99215 |
2278 |
SD |
blood urea nitrogen level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood urea nitrogen amount |
male |
140 days
| 8 |
|
|
36.5 |
mg/dl |
4.9 |
13.86 |
blood urea nitrogen analysis |
0.0 |
unx |
84 |
days |
|
|
|
100156 |
2419 |
SD |
blood albumin level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood albumin amount |
male |
140 days
| 6 |
|
|
3.0 |
g/dl |
0.2 |
0.49 |
automated blood albumin analysis |
0.0 |
unx |
84 |
days |
|
|
|
100162 |
2419 |
SD |
duration of loss of righting reflex |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
balance trait |
female |
0 days
| 16 |
|
|
178.0 |
s |
13.0 |
52.0 |
visual assessment of in vivo video recording |
0.0 |
|
0 |
|
|
time to rigthing reflex post anesthesia |
|
98198 |
2040 |
SD |
plasma angiotensin II level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood angiotensin II amount |
male |
180 days
| 3 |
|
|
50.0 |
pg/ml |
5.77 |
10.0 |
enzyme immunoassay |
0.0 |
|
0 |
|
|
|
|
100229 |
2439 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
6.0 |
mmHg |
1.0 |
2.45 |
vascular transducer tipped catheter |
1.0 |
ACF |
2 |
days |
|
|
|
98822 |
2160 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
58.0 |
mmHg |
2.0 |
4.9 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
5 |
days |
|
|
|
98837 |
2160 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
64.0 |
mmHg |
3.0 |
7.35 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
2 |
days |
|
|
|
98841 |
2160 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
5.9 |
null |
0.3 |
0.73 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
2 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
98870 |
2160 |
SD |
ejection fraction |
artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
cardiac output trait |
male |
0 days
| 6 |
|
|
65.0 |
% |
3.0 |
7.35 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
360 |
min |
|
|
|
98878 |
2160 |
SD |
ejection fraction |
artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
cardiac output trait |
male |
0 days
| 6 |
|
|
75.0 |
% |
3.0 |
7.35 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
5 |
days |
|
|
|
98884 |
2160 |
SD |
change in body weight |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 8 |
|
|
48.0 |
g |
10.96 |
31.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
change from surgery weight |
|
101610 |
2602 |
SD |
food intake rate |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
eating behavior trait |
male |
0 days
| 8 |
|
|
23.0 |
g/d |
2.12 |
6.0 |
unspecified method |
0.0 |
unx |
28 |
days |
|
change from surgery weight |
|
101612 |
2602 |
SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 8 |
|
|
71.0 |
mg |
1.41 |
4.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
|
|
101627 |
2602 |
SD |
plasma potassium level |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood potassium amount |
male |
0 days
| 7 |
|
|
5.0 |
mmol/l |
0.15 |
0.4 |
ex vivo blood analysis |
0.0 |
unx |
28 |
days |
|
|
|
101596 |
2602 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 7 |
|
|
37.2 |
% |
10.02 |
26.5 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
|
|
101604 |
2602 |
SD |
creatinine clearance |
left nephrectomy (for 70 days) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
glomerular filtration trait |
male |
0 days
| 5 |
|
|
1.4 |
ml/min |
0.2 |
0.45 |
serum creatinine analysis |
0.0 |
unx |
70 |
days |
|
|
|
103797 |
2179 |
SD |
body weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 5 |
|
|
302.0 |
g |
6.26 |
14.0 |
body weighing method |
0.0 |
unx |
13 |
days |
|
|
|
101538 |
2602 |
SD |
change in body weight |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 6 |
|
|
84.0 |
g |
4.9 |
12.0 |
body weighing method |
0.0 |
sham unx |
13 |
days |
|
change from surgery weight |
|
101539 |
2602 |
SD |
systolic blood pressure |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 11 |
undefined |
|
185.0 |
mmHg |
7.84 |
26.0 |
tail cuff plethysmography |
0.0 |
unx |
13 |
days |
|
- |
|
101548 |
2602 |
SD |
plasma aldosterone level |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood aldosterone amount |
male |
0 days
| 6 |
|
|
50.0 |
pg/ml |
4.9 |
12.0 |
plasma aldosterone analysis |
0.0 |
sham unx |
13 |
days |
|
|
|
101555 |
2602 |
SD |
plasma aldosterone level |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood aldosterone amount |
male |
0 days
| 11 |
|
|
526.0 |
pg/ml |
78.39 |
260.0 |
plasma aldosterone analysis |
0.0 |
unx |
13 |
days |
|
- |
|
101556 |
2602 |
SD |
plasma aldosterone level |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood aldosterone amount |
male |
0 days
| 5 |
|
|
181.0 |
pg/ml |
55.45 |
124.0 |
plasma aldosterone analysis |
0.0 |
unx |
13 |
days |
|
|
|
101557 |
2602 |
SD |
adrenal gland weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 5 |
|
|
56.0 |
mg |
1.79 |
4.0 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
|
|
|
101561 |
2602 |
SD |
adrenal gland weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
0 days
| 5 |
|
|
60.0 |
mg |
3.13 |
7.0 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
|
|
|
101562 |
2602 |
SD |
plasma renin activity level |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
renin activity |
male |
0 days
| 5 |
|
|
13.3 |
ng/ml/h |
5.5 |
12.3 |
radioimmunoassay |
0.0 |
unx |
13 |
days |
|
|
|
101565 |
2602 |
SD |
plasma renin activity level |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
renin activity |
male |
0 days
| 5 |
|
|
5.2 |
ng/ml/h |
2.24 |
5.0 |
radioimmunoassay |
0.0 |
unx |
13 |
days |
|
|
|
101566 |
2602 |
SD |
left kidney wet weight |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 6 |
|
|
1.19 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
sham unx |
28 |
days |
|
remnant kidney |
|
101579 |
2602 |
SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 6 |
|
|
2.03 |
g |
0.2 |
0.48 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
remnant kidney |
|
101582 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 7 |
|
|
30.0 |
mg/d |
5.67 |
15.0 |
urine protein analysis |
0.0 |
unx |
28 |
days |
|
|
|
101593 |
2602 |
SD |
plasma potassium level |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood potassium amount |
male |
0 days
| 6 |
|
|
5.0 |
mmol/l |
0.24 |
0.6 |
ex vivo blood analysis |
0.0 |
sham unx |
28 |
days |
|
|
|
101595 |
2602 |
SD |
glomerular filtration rate |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
glomerular filtration trait |
male |
90 days
| 9 |
|
|
1.2 |
ml/min |
0.06 |
0.18 |
inulin analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
101224 |
2582 |
SD |
glomerular filtration rate to body weight ratio |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
glomerular filtration trait |
male |
90 days
| 9 |
|
|
0.3 |
ml/min/100g |
0.01 |
0.03 |
inulin analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
101226 |
2582 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 17 |
|
|
915.0 |
cm |
80.28 |
331.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
|
|
98248 |
2040 |
SD |
number of entries into a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 9 |
|
|
24.5 |
null |
5.0 |
15.0 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
|
|
98255 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 17 |
|
|
41.7 |
s |
3.18 |
13.1 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
29 |
days |
|
time to platform |
|
98265 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (210 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (250 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 17 |
|
|
13.6 |
s |
1.92 |
7.9 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
31 |
days |
|
time to platform |
|
98267 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 9 |
|
|
20.6 |
s |
3.7 |
11.1 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
30 |
days |
|
time to platform |
|
98272 |
2040 |
SD |
body weight |
artificial aortocaval fistula (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
body mass |
male |
0 days
| 6 |
|
|
291.0 |
g |
6.0 |
14.7 |
body weighing method |
1.0 |
ACF |
2 |
days |
|
|
|
98773 |
2160 |
SD |
heart weight to body weight ratio |
sham surgical control condition (between 120 and 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
0 days
| 6 |
g/g*103 |
|
3.4 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
5 |
days |
|
|
|
98784 |
2160 |
SD |
systolic blood pressure |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
128.0 |
mmHg |
1.06 |
3.0 |
tail cuff plethysmography |
0.0 |
stz |
154 |
days |
|
|
|
99900 |
2358 |
SD |
body weight |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
body mass |
male |
90 days
| 9 |
|
|
396.0 |
g |
7.6 |
22.8 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
101214 |
2582 |
SD |
hematocrit |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
erythrocyte quantity |
male |
420 days-450 days |
9 |
|
|
45.0 |
% |
1.0 |
3.0 |
hematocrit analysis |
0.0 |
|
0 |
|
|
|
|
101221 |
2582 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-systolic diameter |
male |
0 days
| 6 |
|
|
4.1 |
mm |
0.5 |
1.22 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
5 |
days |
|
|
|
98856 |
2160 |
SD |
body weight |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 7 |
|
|
386.0 |
g |
7.0 |
18.52 |
body weighing method |
0.0 |
unx |
56 |
days |
|
|
|
98934 |
2179 |
SD |
body weight |
left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (40 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
body mass |
male |
0 days
| 7 |
|
|
346.0 |
g |
17.0 |
44.98 |
body weighing method |
0.0 |
unx |
70 |
days |
|
|
|
98937 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 7 |
|
|
115.0 |
mmHg |
2.0 |
5.29 |
tail cuff plethysmography |
0.0 |
unx |
0 |
|
|
|
|
98938 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 7 |
|
|
143.0 |
mmHg |
7.0 |
18.52 |
tail cuff plethysmography |
0.0 |
unx |
28 |
days |
|
|
|
98941 |
2179 |
SD |
mean arterial blood pressure |
left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
arterial blood pressure trait |
male |
0 days
| 7 |
|
|
155.0 |
mmHg |
3.0 |
7.94 |
tail cuff plethysmography |
0.0 |
unx |
56 |
days |
|
|
|
98946 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
0.3 |
mg/d |
0.1 |
0.26 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
0 |
|
|
|
|
98950 |
2179 |
SD |
urine total protein excretion rate |
left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) |
Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. |
total urine protein amount |
male |
0 days
| 7 |
|
|
29.3 |
mg/d |
3.0 |
7.94 |
urine protein sulfosalicylic acid precipitation test |
0.0 |
unx |
28 |
days |
|
|
|
98953 |
2179 |
SD |
systolic blood pressure |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
arterial blood pressure trait |
male |
140 days
| 6 |
|
serial mean |
142.6 |
mmHg |
7.1 |
17.39 |
tail cuff plethysmography |
0.0 |
unx |
84 |
days |
|
|
|
100118 |
2419 |
SD |
creatinine clearance |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
glomerular filtration trait |
male |
140 days
| 6 |
|
|
2.6 |
ml/min |
0.2 |
0.49 |
urine creatinine analysis |
0.0 |
unx |
84 |
days |
|
|
|
100136 |
2419 |
SD |
systolic blood pressure |
controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
arterial blood pressure trait |
male |
140 days
| 6 |
|
serial mean |
113.6 |
mmHg |
4.1 |
10.04 |
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100112 |
2419 |
SD |
blood hemoglobin A1c level |
controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood hemoglobin amount |
male |
140 days
| 6 |
|
|
3.2 |
% |
0.1 |
0.24 |
blood hemoglobin analysis |
0.0 |
x |
0 |
days |
|
|
|
100126 |
2419 |
SD |
body weight |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
body mass |
male |
77 days
| 6 |
|
|
403.2 |
g |
7.4 |
18.13 |
body weighing method |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101075 |
2564 |
SD |
heart weight |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart mass |
male |
77 days
| 6 |
|
|
1.13 |
g |
0.03 |
0.07 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101080 |
2564 |
SD |
heart weight |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart mass |
male |
189 days
| 6 |
|
|
1.41 |
g |
0.06 |
0.15 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101082 |
2564 |
SD |
heart weight to body weight ratio |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart mass |
male |
189 days
| 6 |
|
|
2.66 |
g/kg |
0.04 |
0.1 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101086 |
2564 |
SD |
systolic blood pressure |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
arterial blood pressure trait |
male |
77 days
| 6 |
undefined |
|
134.0 |
mmHg |
2.0 |
4.9 |
tail cuff plethysmography |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101088 |
2564 |
SD |
systolic blood pressure |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
arterial blood pressure trait |
male |
189 days
| 10 |
undefined |
|
143.0 |
mmHg |
3.0 |
9.49 |
tail cuff plethysmography |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101089 |
2564 |
SD |
heart left ventricle weight |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle mass |
male |
189 days
| 6 |
|
|
0.76 |
g |
0.03 |
0.07 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
|
|
101094 |
2564 |
SD |
heart right ventricle weight |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right ventricle mass |
male |
77 days
| 6 |
|
|
0.25 |
g |
0.01 |
0.02 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101099 |
2564 |
SD |
left atrium weight |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left atrium mass |
male |
189 days
| 10 |
|
|
0.05 |
g |
0.0 |
0.01 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101109 |
2564 |
SD |
heart left atrium weight to body weight ratio |
sham surgical control condition (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left atrium mass |
male |
189 days
| 6 |
|
|
0.08 |
mg/g |
0.01 |
0.01 |
ex vivo method |
0.0 |
sham lad occlusion |
140 |
days |
|
law/bw |
|
101114 |
2564 |
SD |
heart septum weight |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart septum morphology trait |
male |
77 days
| 6 |
|
|
0.24 |
g |
0.01 |
0.02 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
septum |
|
101123 |
2564 |
SD |
heart septum weight |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart septum morphology trait |
male |
77 days
| 6 |
|
|
0.23 |
g |
0.01 |
0.02 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
septum |
|
101124 |
2564 |
SD |
body weight |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
body mass |
male |
175 days
| 10 |
|
|
471.0 |
g |
10.0 |
31.62 |
scale |
0.0 |
sham ACF |
105 |
days |
|
|
|
99193 |
2278 |
SD |
heart weight |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
98 days
| 8 |
|
|
0.98 |
g |
0.05 |
0.14 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
|
|
99195 |
2278 |
SD |
heart weight |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
98 days
| 8 |
|
|
1.55 |
g |
0.06 |
0.17 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
|
|
99196 |
2278 |
SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
175 days
| 10 |
|
|
4.8 |
g/kg |
0.3 |
0.95 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
|
|
99202 |
2278 |
SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle mass |
male |
175 days
| 10 |
|
|
1.9 |
mg/g |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
|
|
99205 |
2278 |
SD |
heart right ventricle weight to body weight ratio |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart right ventricle mass |
male |
175 days
| 10 |
|
|
1.0 |
mg/g |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
|
|
99210 |
2278 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
175 days
| 10 |
|
|
82.0 |
mmHg |
4.0 |
12.65 |
vascular transducer tipped catheter |
0.0 |
ACF |
105 |
days |
|
|
|
99222 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
|
9.0 |
mmHg |
1.0 |
3.16 |
vascular transducer tipped catheter |
0.0 |
ACF |
105 |
days |
|
|
|
99226 |
2278 |
SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
|
|
38.0 |
% |
2.0 |
5.29 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
|
|
99367 |
2278 |
SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
|
10.1 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99236 |
2278 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
175 days
| 10 |
|
|
7.4 |
mm |
0.3 |
0.95 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
|
|
99242 |
2278 |
SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
|
77.0 |
g/cm2 |
8.0 |
22.63 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
|
|
99252 |
2278 |
SD |
heart left ventricle interstitial bradykinin level during a period of time |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial bradykinin amount |
male |
98 days
| 8 |
|
|
6.4 |
pg/hr |
0.4 |
1.13 |
radioimmunoassay |
0.0 |
sham ACF |
28 |
days |
|
heart left ventricle interstitial bradykinin level during a period of time |
|
99263 |
2278 |
SD |
heart left ventricle interstitial bradykinin level during a period of time |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial bradykinin amount |
male |
175 days
| 10 |
|
|
12.4 |
pg/hr |
1.7 |
5.38 |
radioimmunoassay |
0.0 |
ACF |
105 |
days |
|
heart left ventricle interstitial bradykinin level during a period of time |
|
99266 |
2278 |
SD |
heart left ventricle interstitial norepinephrine level during a period of time |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial norepinephrine amount |
male |
98 days
| 9 |
|
|
6.8 |
pg/hr |
0.8 |
2.4 |
enzyme linked immunosorbent assay |
0.0 |
ACF |
28 |
days |
|
heart left ventricle interstitial bradykinin level during a period of time |
|
99268 |
2278 |
SD |
heart left ventricle interstitial norepinephrine level during a period of time |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle interstitial norepinephrine amount |
male |
175 days
| 8 |
|
|
5.9 |
pg/hr |
0.4 |
1.13 |
enzyme linked immunosorbent assay |
0.0 |
sham ACF |
105 |
days |
|
heart left ventricle interstitial bradykinin level during a period of time |
|
99269 |
2278 |
SD |
plasma bradykinin level |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood bradykinin amount |
male |
175 days
| 8 |
|
|
17.0 |
pg/ml |
2.0 |
5.66 |
radioimmunoassay |
0.0 |
sham ACF |
105 |
days |
|
|
|
99281 |
2278 |
SD |
plasma norepinephrine level |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood norepinephrine amount |
male |
98 days
| 9 |
|
|
89.0 |
pg/ml |
8.0 |
24.0 |
enzyme linked immunosorbent assay |
0.0 |
ACF |
28 |
days |
|
|
|
99284 |
2278 |
SD |
mean arterial blood pressure |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
arterial blood pressure trait |
male |
72 days
| 5 |
|
|
84.0 |
mmHg |
5.0 |
11.18 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99302 |
2278 |
SD |
left ventricular end-diastolic blood pressure |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
11.0 |
mmHg |
2.0 |
4.47 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99310 |
2278 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
86.0 |
mmHg |
5.0 |
13.23 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99321 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
9386.0 |
mmHg/s |
260.0 |
581.38 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99324 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
-7879.0 |
mmHg/s |
530.0 |
1185.12 |
vascular transducer tipped catheter |
0.0 |
ACF |
2 |
days |
|
|
|
99334 |
2278 |
SD |
maximum rate of negative change in left ventricular blood pressure |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
|
-7379.0 |
mmHg/s |
445.0 |
1177.36 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
28 |
days |
|
|
|
99335 |
2278 |
SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
72 days
| 5 |
|
|
4.3 |
mm |
0.5 |
1.12 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99348 |
2278 |
SD |
systolic blood pressure |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
120 days
| 1 |
mean of 3 samples - 1 per minute |
serial mean |
119.0 |
mmHg |
|
|
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100189 |
2439 |
SD |
both kidneys wet weight as percentage of body weight |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
kidney mass |
male |
60 days
| 3 |
|
|
0.72 |
% |
0.03 |
0.06 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
100192 |
2439 |
SD |
plasma urea nitrogen level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood urea nitrogen amount |
male |
60 days
| 3 |
|
|
6.43 |
mmol/l |
1.65 |
2.86 |
plasma urea nitrogen analysis |
0.0 |
|
0 |
|
|
|
|
100198 |
2439 |
SD |
plasma angiotensin II level |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
blood angiotensin II amount |
male |
60 days
| 3 |
|
|
170.0 |
pg/ml |
92.38 |
160.0 |
enzyme immunoassay |
0.0 |
|
0 |
|
|
|
|
100225 |
2439 |
SD |
systolic blood pressure |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
90 days
| 4 |
mean of 3 samples - 1 per minute |
serial mean |
133.0 |
mmHg |
3.0 |
6.0 |
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100170 |
2439 |
SD |
systolic blood pressure |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
arterial blood pressure trait |
male |
210 days
| 5 |
mean of 3 samples - 1 per minute |
serial mean |
136.0 |
mmHg |
1.79 |
4.0 |
tail cuff plethysmography |
0.0 |
|
0 |
|
|
|
|
100176 |
2439 |
SD |
serum testosterone level |
in utero condition (for 7 days) and corn oil (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
blood testosterone amount |
male |
1 days
| 6 |
|
|
0.81 |
ng/ml |
0.05 |
0.12 |
radioimmunoassay |
1.0 |
|
0 |
|
|
|
|
98732 |
2158 |
SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
16.0 |
g/cm2 |
4.0 |
8.94 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99390 |
2278 |
SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
37.0 |
g/cm2 |
7.0 |
15.65 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
|
|
99398 |
2278 |
SD |
body weight |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
body mass |
male |
0 days
| 8 |
|
|
570.0 |
g |
31.47 |
89.0 |
body weighing method |
0.0 |
stz |
224 |
days |
|
|
|
99915 |
2358 |
SD |
blood glucose level |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
blood glucose amount |
male |
0 days
| 8 |
|
|
98.0 |
mg/dl |
3.18 |
9.0 |
blood glucose analysis |
0.0 |
|
0 |
|
|
|
|
99922 |
2358 |
SD |
renal filtration fraction |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
glomerular filtration trait |
male |
0 days
| 8 |
|
|
0.29 |
null |
0.0 |
0.01 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
stz |
224 |
days |
GFR by inulin method |
|
|
99932 |
2358 |
SD |
retinal uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and quinidine (10 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
187.0 |
% |
22.0 |
38.11 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106115 |
3028 |
SD |
retinal uptake index of digoxin |
tritiated digoxin (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina blood vessel morphology trait |
male |
35 days-49 days |
3 |
|
|
24.0 |
% |
5.8 |
10.05 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
digoxin uptake index |
|
106117 |
3028 |
SD |
aqueous humor uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
14.2 |
% |
3.5 |
6.06 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106134 |
3028 |
SD |
aqueous humor uptake index of digoxin |
tritiated digoxin (10 uCi) (for 0 hours) and digoxin (0.01 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
aqueous humor morphology trait |
male |
35 days-49 days |
3 |
|
|
15.8 |
% |
3.5 |
6.06 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
digoxin uptake index |
|
106136 |
3028 |
SD |
brain uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
blood-brain barrier morphology trait |
male |
35 days-49 days |
3 |
|
|
2.12 |
% |
0.12 |
0.21 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
|
sec post excision |
quinidine uptake index |
|
106150 |
3028 |
SD |
elimination half-life of nifedipine in the plasma |
nifedipine (200 ug/kg) |
Lu J, et al., Sci Rep. 2017 Feb 20;7:42922. doi: 10.1038/srep42922. |
xenobiotic pharmacokinetics trait |
both |
56 days
| 6 |
|
|
35.52 |
min |
8.29 |
20.31 |
liquid chromatography-mass spectrometry |
0.0 |
|
0 |
|
2 hour tail vein blood sampling |
1/2 life nifidepine |
|
105706 |
3020 |
SD |
plasma nifedipine level area under curve |
nifedipine (200 ug/kg) |
Lu J, et al., Sci Rep. 2017 Feb 20;7:42922. doi: 10.1038/srep42922. |
blood xenobiotic amount |
both |
56 days
| 6 |
|
|
30118.55 |
min x (ng/ml) |
2436.55 |
5968.3 |
liquid chromatography-mass spectrometry |
0.0 |
|
0 |
|
2 hour tail vein blood sampling |
min x ng/ml |
|
105712 |
3020 |
SD |
serum total immunoglobulin E level |
vehicle control condition then acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood immunoglobulin E amount |
not specified |
0 days
| 4 |
|
|
0.2 |
ug/l |
0.0 |
0.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105407 |
3015 |
SD |
volume of distribution of nifedipine in the blood |
nifedipine (200 ug/kg) |
Lu J, et al., Sci Rep. 2017 Feb 20;7:42922. doi: 10.1038/srep42922. |
blood xenobiotic amount |
both |
56 days
| 6 |
|
|
341.11 |
ml/kg |
83.37 |
204.21 |
liquid chromatography-mass spectrometry |
0.0 |
|
0 |
|
2 hour tail vein blood sampling |
ml/kg |
|
105714 |
3020 |
SD |
serum total immunoglobulin E level |
acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood immunoglobulin E amount |
not specified |
0 days
| 12 |
|
|
0.28 |
ug/l |
0.01 |
0.05 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105409 |
3015 |
SD |
serum interleukin-9 level |
acetic acid (for 0 hours) then physical restraint in tube type rodent restrainer (for 2 hours) then fasting (for 1 days) |
Zhuang ZM, et al., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015. |
blood interleukin-9 amount |
not specified |
0 days
| 12 |
|
|
0.21 |
ug/l |
0.0 |
0.01 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
error not defined |
|
105417 |
3015 |
SD |
body weight |
control condition |
Eisenberger U, etal., Ren Physiol Biochem. 1995 Mar-Apr;18(2):89-96. doi: 10.1159/000173904. |
body mass |
female |
96 days-121 days |
7 |
|
|
201.0 |
g |
4.91 |
13.0 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
110176 |
3166 |
SD |
urine total protein excretion rate |
doxorubicin (5 mg/kg) (between 6 and 7 days) |
Eisenberger U, etal., Ren Physiol Biochem. 1995 Mar-Apr;18(2):89-96. doi: 10.1159/000173904. |
total urine protein amount |
female |
96 days-121 days |
7 |
|
|
42.8 |
mg/d |
4.72 |
12.5 |
Bradford protein assay |
0.0 |
|
0 |
|
|
|
records do not display, fixed. |
110186 |
3166 |
SD |
creatinine clearance to body weight ratio |
control condition |
Eisenberger U, etal., Ren Physiol Biochem. 1995 Mar-Apr;18(2):89-96. doi: 10.1159/000173904. |
glomerular filtration trait |
female |
96 days-121 days |
7 |
|
|
0.84 |
ml/min/100g |
0.05 |
0.13 |
creatinine analysis by Jaffe reaction with spectrophotometric readout |
0.0 |
|
0 |
|
|
|
|
110188 |
3166 |
SD |
creatinine clearance to body weight ratio |
doxorubicin (5 mg/kg) (between 6 and 7 days) |
Eisenberger U, etal., Ren Physiol Biochem. 1995 Mar-Apr;18(2):89-96. doi: 10.1159/000173904. |
glomerular filtration trait |
female |
96 days-121 days |
7 |
|
|
0.74 |
ml/min/100g |
0.08 |
0.2 |
creatinine analysis by Jaffe reaction with spectrophotometric readout |
0.0 |
|
0 |
|
|
|
|
110189 |
3166 |
SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57 days-71 days |
6 |
|
|
21.4 |
g/d |
|
|
unspecified method |
0.0 |
|
0 |
|
|
|
|
84865 |
1602 |
SD |
blood urea nitrogen level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood urea nitrogen amount |
female |
71 days-85 days |
6 |
|
|
13.3 |
mg/dl |
0.96 |
2.34 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85042 |
1602 |
SD |
blood albumin level to blood globulin level ratio |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood albumin amount |
female |
71 days-85 days |
6 |
|
|
0.9 |
null |
0.02 |
0.06 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85053 |
1602 |
SD |
blood alanine aminotransferase activity level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
male |
71 days-85 days |
6 |
|
|
59.2 |
U/l |
3.65 |
8.95 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85084 |
1602 |
SD |
blood alanine aminotransferase activity level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alanine transaminase amount |
female |
71 days-85 days |
6 |
|
|
46.83 |
U/l |
2.69 |
6.59 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85089 |
1602 |
SD |
blood alkaline phosphatase activity level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood alkaline phosphatase amount |
male |
71 days-85 days |
6 |
|
|
295.8 |
U/l |
32.68 |
80.04 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85098 |
1602 |
SD |
blood potassium level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
male |
71 days-85 days |
6 |
|
|
5.0 |
mmol/l |
0.06 |
0.14 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85131 |
1602 |
SD |
blood phosphate level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood phosphate amount |
male |
85 days-99 days |
6 |
|
|
4.87 |
mg/dl |
0.9 |
2.2 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85159 |
1602 |
SD |
liver wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
71 days-85 days |
6 |
|
|
3.65 |
g |
0.12 |
0.29 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85194 |
1602 |
SD |
both kidneys wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
71 days-85 days |
6 |
|
|
0.85 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85208 |
1602 |
SD |
heart wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
85 days-99 days |
6 |
|
|
0.36 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85235 |
1602 |
SD |
heart wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
71 days-85 days |
6 |
|
|
0.42 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85238 |
1602 |
SD |
spleen wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
85 days-99 days |
6 |
|
|
0.17 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85246 |
1602 |
SD |
spleen wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
71 days-85 days |
6 |
|
|
0.24 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85252 |
1602 |
SD |
testis wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
71 days-85 days |
6 |
|
|
1.19 |
g |
0.08 |
0.19 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
85279 |
1602 |
SD |
body weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
male |
70 days-84 days |
6 |
|
|
257.3 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84764 |
1602 |
SD |
body weight |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
body mass |
female |
50 days-64 days |
6 |
|
|
147.0 |
g |
|
|
body weighing method |
0.0 |
|
0 |
|
|
|
|
84810 |
1602 |
SD |
platelet count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
71 days-85 days |
6 |
|
|
1177.5 |
x 1000 cells/ul |
83.55 |
204.66 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84977 |
1602 |
SD |
body weight |
artificial aortocaval fistula (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
body mass |
male |
0 days
| 6 |
|
|
302.0 |
g |
5.0 |
12.25 |
body weighing method |
1.0 |
ACF |
360 |
min |
|
|
|
98755 |
2160 |
SD |
blood potassium level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood potassium amount |
male |
71 days-85 days |
6 |
|
|
5.4 |
mmol/l |
0.11 |
0.26 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85134 |
1602 |
SD |
blood triglyceride level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood triglyceride amount |
female |
85 days-99 days |
6 |
|
|
23.83 |
mg/dl |
1.49 |
3.66 |
automated blood analysis |
0.0 |
|
0 |
|
Siemens biochemical analyzer |
|
|
85190 |
1602 |
SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
0 days
| 6 |
g/g*103 |
|
2.2 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
360 |
min |
|
|
|
98785 |
2160 |
SD |
heart rate |
sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
395.0 |
beats/min |
11.0 |
26.94 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
720 |
min |
|
|
|
98796 |
2160 |
SD |
heart rate |
artificial aortocaval fistula (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) then xylazine (10 mg/kg) and ketamine (80 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart pumping trait |
male |
0 days
| 6 |
|
|
378.0 |
beats/min |
10.0 |
24.49 |
HP Sonos 5500 echo ultrasound |
1.0 |
ACF |
2 |
days |
|
|
|
98803 |
2160 |
SD |
mean arterial blood pressure |
sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
arterial blood pressure trait |
male |
0 days
| 6 |
|
|
103.0 |
mmHg |
6.0 |
14.7 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
360 |
min |
|
|
|
98807 |
2160 |
SD |
blood urea nitrogen level |
nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) |
Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. |
blood urea nitrogen amount |
male |
140 days
| 6 |
|
|
38.2 |
mg/dl |
9.0 |
22.05 |
blood urea nitrogen analysis |
0.0 |
unx |
84 |
days |
|
|
|
100158 |
2419 |
SD |
effective renal plasma flow |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney plasma flow trait |
male |
0 days
| 8 |
|
|
2.31 |
ml/min/100g |
0.06 |
0.16 |
p-aminohippurate analysis by liquid phase colorimetry |
0.0 |
stz |
154 |
days |
|
|
|
99906 |
2358 |
SD |
left kidney wet weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
0 days
| 5 |
|
|
1.16 |
g |
0.11 |
0.25 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
|
remnant kidney |
|
101545 |
2602 |
SD |
urine total protein excretion rate |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
0 days
| 5 |
|
|
87.0 |
mg/d |
12.52 |
28.0 |
urine protein analysis |
0.0 |
unx |
13 |
days |
|
|
|
101554 |
2602 |
SD |
change in body weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
0 days
| 7 |
|
|
97.0 |
g |
7.56 |
20.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
change from surgery weight |
|
101577 |
2602 |
SD |
systolic blood pressure |
unilateral nephrectomy (for 14 days) then spironolactone (5.56 mg/kg/d) (for 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
0 days
| 8 |
undefined |
|
192.0 |
mmHg |
7.07 |
20.0 |
tail cuff plethysmography |
0.0 |
unx |
14 |
days |
|
|
|
101616 |
2602 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 8 |
|
|
26.0 |
% |
3.89 |
11.0 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
|
|
101630 |
2602 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 7 |
|
|
4.7 |
% |
1.97 |
5.2 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
|
|
101605 |
2602 |
SD |
total horizontal distance resulting from voluntary locomotion in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 8 |
|
|
724.0 |
cm |
144.96 |
410.0 |
elevated plus maze apparatus method |
300.0 |
sham coronal plane rotational acceleration of the head |
2 |
days |
|
- |
|
98204 |
2040 |
SD |
left ventricular end-diastolic blood pressure |
sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricular blood pressure trait |
male |
0 days
| 6 |
|
|
2.0 |
mmHg |
1.0 |
2.45 |
vascular transducer tipped catheter |
1.0 |
sham ACF |
5 |
days |
|
|
|
98825 |
2160 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle end-diastolic diameter |
male |
0 days
| 6 |
|
|
4.4 |
null |
0.4 |
0.98 |
HP Sonos 5500 echo ultrasound |
1.0 |
sham ACF |
360 |
min |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
98867 |
2160 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 8 |
|
|
10.0 |
s |
1.2 |
3.4 |
Morris water maze method |
60.0 |
sham coronal plane rotational acceleration of the head |
31 |
days |
|
time to platform |
|
98264 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 9 |
|
|
28.0 |
s |
3.53 |
10.6 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
29 |
days |
|
time to platform |
|
98271 |
2040 |
SD |
time to locate a hidden target platform in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
spatial reference memory trait |
female |
0 days
| 9 |
|
|
17.0 |
s |
3.37 |
10.1 |
Morris water maze method |
60.0 |
coronal plane rotational acceleration of the head |
31 |
days |
|
time to platform |
|
98273 |
2040 |
SD |
body weight |
sham surgical control condition (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
body mass |
male |
0 days
| 6 |
|
|
271.0 |
g |
6.0 |
14.7 |
body weighing method |
1.0 |
sham ACF |
720 |
min |
|
|
|
98772 |
2160 |
SD |
heart weight to body weight ratio |
sham surgical control condition (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
0 days
| 6 |
g/g*103 |
|
3.3 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
360 |
min |
|
|
|
98778 |
2160 |
SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 5 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
0 days
| 6 |
g/g*103 |
|
4.2 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
5 |
days |
|
|
|
98783 |
2160 |
SD |
glomerular filtration rate |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
glomerular filtration trait |
male |
420 days-450 days |
9 |
|
|
1.63 |
ml/min |
0.12 |
0.36 |
inulin analysis by liquid phase colorimetry |
0.0 |
|
0 |
|
|
|
|
101225 |
2582 |
SD |
plasma bradykinin level |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
blood bradykinin amount |
male |
98 days
| 9 |
|
|
28.0 |
pg/ml |
2.0 |
6.0 |
radioimmunoassay |
0.0 |
ACF |
28 |
days |
|
|
|
99280 |
2278 |
SD |
heart rate |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart pumping trait |
male |
98 days
| 8 |
|
|
307.0 |
beats/min |
3.0 |
8.49 |
vascular transducer tipped catheter |
0.0 |
ACF |
28 |
days |
|
|
|
99296 |
2278 |
SD |
left ventricular end-systolic blood pressure |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
58.0 |
mmHg |
2.0 |
4.47 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99317 |
2278 |
SD |
maximum rate of positive change in left ventricular blood pressure |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
|
8301.0 |
mmHg/s |
442.0 |
988.34 |
vascular transducer tipped catheter |
0.0 |
sham ACF |
2 |
days |
|
|
|
99325 |
2278 |
SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
lvedd/pw |
|
5.4 |
null |
0.4 |
0.89 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
|
99358 |
2278 |
SD |
left atrium weight |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left atrium mass |
male |
77 days
| 6 |
|
|
0.04 |
g |
0.0 |
0.0 |
ex vivo method |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101107 |
2564 |
SD |
heart left atrium weight to body weight ratio |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left atrium mass |
male |
189 days
| 10 |
|
|
0.08 |
mg/g |
0.01 |
0.02 |
ex vivo method |
0.0 |
lad occlusion |
140 |
days |
|
law/bw |
|
101113 |
2564 |
SD |
right atrium weight |
sham surgical control condition (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart right atrium mass |
male |
77 days
| 6 |
|
|
0.04 |
g |
0.0 |
0.0 |
ex vivo method |
0.0 |
sham lad occlusion |
28 |
days |
|
|
|
101116 |
2564 |
SD |
amount of experiment time spent in a discrete space in an experimental apparatus |
isoflurane (4 %) (between 0.1 and 0.2 hours) then carprofen (5 mg/kg) (for 0 hours) then coronal plane rotational acceleration of the head (360 krad/s2) (for 0 hours) and coronal plane rotational acceleration of the head (380 rad/s2) (for 0 hours) |
Stemper BD, et al., Ann Biomed Eng. 2016 Nov;44(11):3252-3265. Epub 2016 May 17. |
locomotor behavior trait |
female |
0 days
| 16 |
|
|
78.4 |
s |
9.28 |
37.1 |
elevated plus maze apparatus method |
300.0 |
coronal plane rotational acceleration of the head |
2 |
days |
|
time in open arms |
|
98226 |
2040 |
SD |
hematocrit |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
85 days-99 days |
6 |
|
|
45.18 |
% |
0.87 |
2.13 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84956 |
1602 |
SD |
hematocrit |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
85 days-99 days |
6 |
|
|
41.5 |
% |
0.64 |
1.57 |
unspecified method |
0.0 |
|
0 |
|
|
|
|
84962 |
1602 |
SD |
both kidneys wet weight as percentage of body weight |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
kidney mass |
male |
180 days
| 5 |
|
|
0.6 |
% |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
100196 |
2439 |
SD |
body weight |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
body mass |
male |
0 days
| 8 |
|
|
675.0 |
g |
12.37 |
35.0 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
99892 |
2358 |