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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1aCondition 1bCondition 1cCondition 2aCondition 2bCondition 2cCondition 3
37urine creatinine excretion rateLH/Mavmale8.6mg/dstreptozotocin (75 mg/kg) 102652streptozotocin (75 mg/kg)
8urine creatinine excretion rateLH/Mavmale8mg/dvehicle control condition102651vehicle control condition
16pulse pressureLH/Mavmale43.3mmHgnaive control condition11650naive control condition
37blood glucose levelLH/Mavmale300mg/dlstreptozotocin (75 mg/kg) then fasting (for 16 hours) then glucose (2 g/kg) (for 1 hours)102661streptozotocin (75 mg/kg) fasting (for 16 hours)glucose (2 g/kg) (for 1 hours)
8blood glucose levelLH/Mavmale121mg/dlvehicle control condition then fasting (for 16 hours) then glucose (2 g/kg) (for 1 hours)102660vehicle control conditionfasting (for 16 hours)glucose (2 g/kg) (for 1 hours)
37blood glucose levelLH/Mavmale70mg/dlstreptozotocin (75 mg/kg) then fasting (for 16 hours)102658streptozotocin (75 mg/kg) fasting (for 16 hours)
8blood glucose levelLH/Mavmale67mg/dlvehicle control condition then fasting (for 16 hours)102657vehicle control conditionfasting (for 16 hours)
7heart left ventricle weight to body weight ratioLH/Mavmale24.2mg/gstreptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and hydrochlorothiazide (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days)102685streptozotocin (75 mg/kg) hydralazine (75 mg/kg/d) (for 56 days)hydrochlorothiazide (15 mg/kg/d) (for 56 days)reserpine (0.75 ml/kg/d) (for 56 days)
11heart left ventricle weight to body weight ratioLH/Mavmale19.9mg/gstreptozotocin (75 mg/kg) then Perindopril (1 mg/kg/d) (for 56 days)102684streptozotocin (75 mg/kg) Perindopril (1 mg/kg/d) (for 56 days)
9heart left ventricle weight to body weight ratioLH/Mavmale23.8mg/gstreptozotocin (75 mg/kg) then Perindopril (0.01 mg/kg/d) (for 56 days)102683streptozotocin (75 mg/kg) Perindopril (0.01 mg/kg/d) (for 56 days)
8heart left ventricle weight to body weight ratioLH/Mavmale24.4mg/gstreptozotocin (75 mg/kg) 102682streptozotocin (75 mg/kg)
5heart left ventricle weight to body weight ratioLH/Mavmale2.43mg/gnaive control condition (for 0 hours)103485naive control condition (for 0 hours)
37systolic blood pressureLH/Mavmale145mmHgstreptozotocin (75 mg/kg) 102646streptozotocin (75 mg/kg)
8systolic blood pressureLH/Mavmale136mmHgvehicle control condition102645vehicle control condition
5systolic blood pressureLH/Mavmale161mmHgnaive control condition (for 0 hours)103473naive control condition (for 0 hours)
10systolic blood pressureLH/Mavmale133mmHghydralazine (75 mg/kg/d) (for 42 days) and hydrochlorothiazide (15 mg/kg/d) (for 42 days) and reserpine (0.75 mg/kg/d) (for 42 days)102852hydralazine (75 mg/kg/d) (for 42 days)hydrochlorothiazide (15 mg/kg/d) (for 42 days)reserpine (0.75 mg/kg/d) (for 42 days)
7systolic blood pressureLH/Mavmale144mmHgnifedipine (50 mg/kg/d) (for 42 days)102851nifedipine (50 mg/kg/d) (for 42 days)
7systolic blood pressureLH/Mavmale113mmHgPerindopril (1.5 mg/kg/d) (for 42 days)102850Perindopril (1.5 mg/kg/d) (for 42 days)
8systolic blood pressureLH/Mavmale160mmHgvehicle control condition102849vehicle control condition
8systolic blood pressureLH/Mavmale160mmHgvehicle control condition102848vehicle control condition
4systolic blood pressureLH/Mavmale157mmHgnaive control condition102809naive control condition
8systolic blood pressureLH/Mavmale169mmHgnaive control condition102808naive control condition
16systolic blood pressureLH/Mavmale174.1mmHgnaive control condition11645naive control condition
7plasma creatinine levelLH/Mavmale0.589mg/dlstreptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and hydrochlorothiazide (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days)102679streptozotocin (75 mg/kg) hydralazine (75 mg/kg/d) (for 56 days)hydrochlorothiazide (15 mg/kg/d) (for 56 days)reserpine (0.75 ml/kg/d) (for 56 days)
11plasma creatinine levelLH/Mavmale0.536mg/dlstreptozotocin (75 mg/kg) then Perindopril (1 mg/kg/d) (for 56 days)102678streptozotocin (75 mg/kg) Perindopril (1 mg/kg/d) (for 56 days)
9plasma creatinine levelLH/Mavmale0.544mg/dlstreptozotocin (75 mg/kg) then Perindopril (0.01 mg/kg/d) (for 56 days)102677streptozotocin (75 mg/kg) Perindopril (0.01 mg/kg/d) (for 56 days)
8plasma creatinine levelLH/Mavmale0.61mg/dlstreptozotocin (75 mg/kg) 102676streptozotocin (75 mg/kg)
16diastolic blood pressureLH/Mavmale118.4mmHgnaive control condition11647naive control condition
7plasma triglyceride levelLH/Mavmale1.58mmol/lstreptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and hydrochlorothiazide (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days)102673streptozotocin (75 mg/kg) hydralazine (75 mg/kg/d) (for 56 days)hydrochlorothiazide (15 mg/kg/d) (for 56 days)reserpine (0.75 ml/kg/d) (for 56 days)
11plasma triglyceride levelLH/Mavmale1.5mmol/lstreptozotocin (75 mg/kg) then Perindopril (1 mg/kg/d) (for 56 days)102672streptozotocin (75 mg/kg) Perindopril (1 mg/kg/d) (for 56 days)
10plasma triglyceride levelLH/Mavmale2.42mmol/lstreptozotocin (75 mg/kg) then Perindopril (0.01 mg/kg/d) (for 56 days)102671streptozotocin (75 mg/kg) Perindopril (0.01 mg/kg/d) (for 56 days)
9plasma triglyceride levelLH/Mavmale1.96mmol/lstreptozotocin (75 mg/kg) 102670streptozotocin (75 mg/kg)
8plasma triglyceride levelLH/Mavmale1.57mmol/lvehicle control condition102669vehicle control condition
6body weightLH/Mavmale372gPerindopril (0.04 mg/kg/d) (for 98 days)102793Perindopril (0.04 mg/kg/d) (for 98 days)
6body weightLH/Mavmale391gPerindopril (0.01 mg/kg/d) (for 98 days)102792Perindopril (0.01 mg/kg/d) (for 98 days)
4body weightLH/Mavmale374gnaive control condition102791naive control condition
8body weightLH/Mavmale405gPerindopril (0.4 mg/kg/d) (for 98 days)102790Perindopril (0.4 mg/kg/d) (for 98 days)
8body weightLH/Mavmale404gPerindopril (0.1 mg/kg/d) (for 98 days)102789Perindopril (0.1 mg/kg/d) (for 98 days)
8body weightLH/Mavmale394gPerindopril (0.04 mg/kg/d) (for 98 days)102788Perindopril (0.04 mg/kg/d) (for 98 days)
8body weightLH/Mavmale391gnaive control condition102787naive control condition
37body weightLH/Mavmale233gstreptozotocin (75 mg/kg) 102643streptozotocin (75 mg/kg)
8body weightLH/Mavmale232gvehicle control condition102642vehicle control condition
6body weightLH/Mavmale457gPerindopril (0.04 mg/kg/d) (for 98 days)102807Perindopril (0.04 mg/kg/d) (for 98 days)
6body weightLH/Mavmale460gPerindopril (0.01 mg/kg/d) (for 98 days)102806Perindopril (0.01 mg/kg/d) (for 98 days)
4body weightLH/Mavmale431gnaive control condition102805naive control condition
8body weightLH/Mavmale459gPerindopril (0.4 mg/kg/d) (for 98 days)102804Perindopril (0.4 mg/kg/d) (for 98 days)
8body weightLH/Mavmale452gPerindopril (0.1 mg/kg/d) (for 98 days)102803Perindopril (0.1 mg/kg/d) (for 98 days)
8body weightLH/Mavmale442gPerindopril (0.04 mg/kg/d) (for 98 days)102802Perindopril (0.04 mg/kg/d) (for 98 days)
8body weightLH/Mavmale442gnaive control condition102801naive control condition
5body weightLH/Mavmale360gnaive control condition (for 0 hours)103479naive control condition (for 0 hours)
4urine protein excretion rateLH/Mavmale370mg/dnaive control condition102813naive control condition
8urine protein excretion rateLH/Mavmale260mg/dnaive control condition102812naive control condition
4urine protein excretion rateLH/Mavmale191mg/dnaive control condition102811naive control condition
8urine protein excretion rateLH/Mavmale182mg/dnaive control condition102810naive control condition
37timed urine volumeLH/Mavmale12.6ml/dstreptozotocin (75 mg/kg) 102649streptozotocin (75 mg/kg)
8timed urine volumeLH/Mavmale8.7ml/dvehicle control condition102648vehicle control condition
7plasma total cholesterol levelLH/Mavmale110.8107mg/dlstreptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and hydrochlorothiazide (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days)102667streptozotocin (75 mg/kg) hydralazine (75 mg/kg/d) (for 56 days)hydrochlorothiazide (15 mg/kg/d) (for 56 days)reserpine (0.75 ml/kg/d) (for 56 days)
11plasma total cholesterol levelLH/Mavmale73.359mg/dlstreptozotocin (75 mg/kg) then Perindopril (1 mg/kg/d) (for 56 days)102666streptozotocin (75 mg/kg) Perindopril (1 mg/kg/d) (for 56 days)
10plasma total cholesterol levelLH/Mavmale83.7837mg/dlstreptozotocin (75 mg/kg) then Perindopril (0.01 mg/kg/d) (for 56 days)102665streptozotocin (75 mg/kg) Perindopril (0.01 mg/kg/d) (for 56 days)
9plasma total cholesterol levelLH/Mavmale82.2393mg/dlstreptozotocin (75 mg/kg) 102664streptozotocin (75 mg/kg)
8plasma total cholesterol levelLH/Mavmale66.4092mg/dlvehicle control condition102663vehicle control condition
8urine protein level to urine creatinine level ratioLH/Mavmale5.9vehicle control condition102654vehicle control condition
37urine protein level to urine creatinine level ratioLH/Mavmale9.3streptozotocin (75 mg/kg) 102655streptozotocin (75 mg/kg)
10renal blood flow rate to kidney weight ratioLH/Mavmale4.7ml/min/ghydralazine (75 mg/kg/d) (for 63 days) and hydrochlorothiazide (15 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) 102856hydralazine (75 mg/kg/d) (for 63 days)hydrochlorothiazide (15 mg/kg/d) (for 63 days)reserpine (0.75 mg/kg/d) (for 63 days)ketamine (20 mg/kg) thiobutabarbital (75 mg/kg)
7renal blood flow rate to kidney weight ratioLH/Mavmale4.9ml/min/gnifedipine (50 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) 102855nifedipine (50 mg/kg/d) (for 63 days)ketamine (20 mg/kg) thiobutabarbital (75 mg/kg)
7renal blood flow rate to kidney weight ratioLH/Mavmale5.3ml/min/gPerindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) 102854Perindopril (1.5 mg/kg/d) (for 63 days)ketamine (20 mg/kg) thiobutabarbital (75 mg/kg)
8renal blood flow rate to kidney weight ratioLH/Mavmale5ml/min/gvehicle control condition then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) 102853vehicle control conditionketamine (20 mg/kg) thiobutabarbital (75 mg/kg)
10renal vascular resistance to kidney weight ratioLH/Mavmale27ml/min/g/mmHghydralazine (75 mg/kg/d) (for 63 days) and hydrochlorothiazide (15 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) 102869hydralazine (75 mg/kg/d) (for 63 days)hydrochlorothiazide (15 mg/kg/d) (for 63 days)reserpine (0.75 mg/kg/d) (for 63 days)ketamine (20 mg/kg) thiobutabarbital (75 mg/kg)
7renal vascular resistance to kidney weight ratioLH/Mavmale37ml/min/g/mmHgnifedipine (50 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) 102868nifedipine (50 mg/kg/d) (for 63 days)ketamine (20 mg/kg) thiobutabarbital (75 mg/kg)
7renal vascular resistance to kidney weight ratioLH/Mavmale23ml/min/g/mmHgPerindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) 102858Perindopril (1.5 mg/kg/d) (for 63 days)ketamine (20 mg/kg) thiobutabarbital (75 mg/kg)
8renal vascular resistance to kidney weight ratioLH/Mavmale33ml/min/g/mmHgvehicle control condition then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) 102857vehicle control conditionketamine (20 mg/kg) thiobutabarbital (75 mg/kg)
7both kidneys wet weight to body weight ratioLH/Mavmale8.05g/kgstreptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and hydrochlorothiazide (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days)102697streptozotocin (75 mg/kg) hydralazine (75 mg/kg/d) (for 56 days)hydrochlorothiazide (15 mg/kg/d) (for 56 days)reserpine (0.75 ml/kg/d) (for 56 days)
11both kidneys wet weight to body weight ratioLH/Mavmale6.44g/kgstreptozotocin (75 mg/kg) then Perindopril (1 mg/kg/d) (for 56 days)102696streptozotocin (75 mg/kg) Perindopril (1 mg/kg/d) (for 56 days)
9both kidneys wet weight to body weight ratioLH/Mavmale7.02g/kgstreptozotocin (75 mg/kg) then Perindopril (0.01 mg/kg/d) (for 56 days)102695streptozotocin (75 mg/kg) Perindopril (0.01 mg/kg/d) (for 56 days)
8both kidneys wet weight to body weight ratioLH/Mavmale6.95g/kgstreptozotocin (75 mg/kg) 102694streptozotocin (75 mg/kg)
7aorta weight to body weight ratioLH/Mavmale12.5mg/100gstreptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and hydrochlorothiazide (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days)102691streptozotocin (75 mg/kg) hydralazine (75 mg/kg/d) (for 56 days)hydrochlorothiazide (15 mg/kg/d) (for 56 days)reserpine (0.75 ml/kg/d) (for 56 days)
11aorta weight to body weight ratioLH/Mavmale10.1mg/100gstreptozotocin (75 mg/kg) then Perindopril (1 mg/kg/d) (for 56 days)102690streptozotocin (75 mg/kg) Perindopril (1 mg/kg/d) (for 56 days)
9aorta weight to body weight ratioLH/Mavmale12.3mg/100gstreptozotocin (75 mg/kg) then Perindopril (0.01 mg/kg/d) (for 56 days)102689streptozotocin (75 mg/kg) Perindopril (0.01 mg/kg/d) (for 56 days)
8aorta weight to body weight ratioLH/Mavmale13.5mg/100gstreptozotocin (75 mg/kg) 102688streptozotocin (75 mg/kg)