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Study IDStudyExperiment NameExperiment NotesStrain Ont IDStrainSexAge# of AnimalsSample NotesClinical Measurement Ont IDPhenotypeFormulaClinical Measurement NotesAverage TypeValueUnitsSEMSDMethod Ont IDMethodMethod SiteMethod DurationMethod NotesPost Insult TypePost Insult Time ValuePost Insult Time UnitConditionsRecord IDCondition 1Condition 2aCondition 2bCondition 3Condition 4
526PhysGen Lung datalung massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days10CMO:0000102lung dry weight to body weight ratio1.0326g/kg0.0480.1519MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)57575air oxygen content (12 %) (for 14 days)
526PhysGen Lung datalung massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days15CMO:0000102lung dry weight to body weight ratio1.3583g/kg0.04440.1719MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)57577air oxygen content (12 %) (for 14 days)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000703calculated pulmonary vascular resistance normalized to body weight0.1465mmHg x min x kg x ml-10.00620.0186MMO:0000203fluid-filled catheter with pressure transducer in isolated perfused lungair oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)57683air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days10CMO:0000703calculated pulmonary vascular resistance normalized to body weight0.1343mmHg x min x kg x ml-10.00660.0208MMO:0000203fluid-filled catheter with pressure transducer in isolated perfused lungair oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)57685air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
526PhysGen Lung datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days7CMO:0000713dose of methacholine at which pulmonary conductance is half its pretreatment value2.8517mg/kg0.98322.6012MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)57765air oxygen content (12 %) (for 14 days)methacholine (0-11.06 mg/kg) drug dose time series (for 0.2 hours)
526PhysGen Lung datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days8CMO:0000713dose of methacholine at which pulmonary conductance is half its pretreatment value4.1478mg/kg1.11633.1574MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)57767air oxygen content (12 %) (for 14 days)methacholine (0-11.06 mg/kg) drug dose time series (for 0.2 hours)
461PhysGen Cardiac dataheart massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000069heart wet weight1.269g0.04070.1288MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)45030air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataheart massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000069heart wet weight1.034g0.03780.1196MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)45032air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataarterial blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000198arterial blood flow rate14.758ml/min/g0.49991.5809MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)45083air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataarterial blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days9CMO:0000198arterial blood flow rate14.6111ml/min/g0.63791.9136MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)45085air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000664time to peak heart contraction1139.633s43.4304137.3391MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)45103air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000664time to peak heart contraction1139.166s46.2308146.1945MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)45105air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000007left ventricular systolic blood pressure136.653mmHg5.531917.4935MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)49802air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000007left ventricular systolic blood pressure148.93mmHg4.341913.7302MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)49804air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000002heart rate257.167beats/min13.09241.4004MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)49972air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000002heart rate250.691beats/min6.165819.498MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)49974air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac databody massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000012body weight251.5g4.414.0MMO:0000017whole body digital scaleair oxygen content (12 %) (for 14 days)50081air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac databody massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000012body weight190.4g7.423.4MMO:0000017whole body digital scaleair oxygen content (12 %) (for 14 days)50083air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataheart muscle contractility traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000665heart contraction pressure49.4mmHg4.693314.8414MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)49589air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart muscle contractility traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000665heart contraction pressure47.1mmHg2.58828.1847MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)49591air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000754percent change in left ventricular systolic blood pressurepost-ischemic value/pre-ischemic value x 100%67.5065%6.427820.3265MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49653air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000754percent change in left ventricular systolic blood pressurepost-ischemic value/pre-ischemic value x 100%58.7035%10.357732.754MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49655air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricle integrity traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000695heart left ventricle infarction weight to total heart left ventricle weight ratio9.359%4.434214.022MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours)49030air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 3 hours)
461PhysGen Cardiac dataheart left ventricle integrity traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000695heart left ventricle infarction weight to total heart left ventricle weight ratio6.648%3.606311.404MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours)49032air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 3 hours)
461PhysGen Cardiac dataheart massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000074heart weight to body weight ratio5.044g/kg0.1270.401MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)49145air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataheart massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000074heart weight to body weight ratio5.458g/kg0.1480.469MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)49147air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000742percent change in heart ratepost-ischemic value/pre-ischemic value x 100%131.5896%25.945282.0458MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49262air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000742percent change in heart ratepost-ischemic value/pre-ischemic value x 100%96.6774%10.151632.1021MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49264air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000007left ventricular systolic blood pressure91.208mmHg7.776124.5902MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49274air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days9CMO:0000007left ventricular systolic blood pressure95.7611mmHg10.852132.5564MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49276air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
381PhysGen Respiratory dataarterial blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days7CMO:0000009mean arterial blood pressure119.3986mmHg7.028318.5953MMO:0000013vascular fluid filled catheterair oxygen content (12 %) (for 0.1 hours)13878air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory dataarterial blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days9CMO:0000009mean arterial blood pressure109.2544mmHg8.686526.0594MMO:0000013vascular fluid filled catheterair oxygen content (12 %) (for 0.1 hours)13880air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000532percent change in tidal volume101.4774%3.302910.9545MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)54191air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000532percent change in tidal volume96.1166%1.48615.3582MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)54198air oxygen content (12 %) (between 0.1 and 0.1 hours)
401PhysGen Biochemistry datablood cholesterol amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000363serum total cholesterol level73.2222mg/dl3.534710.604MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36464air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood cholesterol amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000363serum total cholesterol level62.3333mg/dl5.123515.3704MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36466air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood total protein amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000661serum total protein level5.8778g/dl0.11520.3456MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36263air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood total protein amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000661serum total protein level6.7667g/dl0.14240.4272MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36265air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte size traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000038mean corpuscular volume63.7778fl0.55521.6657MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)36287air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte size traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000038mean corpuscular volume59.4889fl0.36611.0982MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)36289air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood glucose amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000543serum glucose level166.6667mg/dl7.664922.9946MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36321air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood glucose amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000543serum glucose level156.5556mg/dl11.246133.7384MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36323air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000037hematocrit56.5222%0.7312.193MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)36346air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000037hematocrit51.5556%1.43094.2928MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)36348air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000290mean corpuscular hemoglobin20.8556pg0.18570.557MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)36356air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000290mean corpuscular hemoglobin19.4667pg0.18480.5545MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)36358air oxygen content (12 %) (for 14 days)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days8CMO:0000709methylene blue metabolism-surface area product without auto-oxidation6.2756ml/min/kg0.35821.013MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58836air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days10CMO:0000709methylene blue metabolism-surface area product without auto-oxidation8.5929ml/min/kg0.74142.3445MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58838air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
381PhysGen Respiratory datablood carbon dioxide amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days5CMO:0000283partial pressure of blood carbon dioxide (Pco2)28.81mmHg1.59773.5725MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)16365air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood carbon dioxide amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days7CMO:0000283partial pressure of blood carbon dioxide (Pco2)26.5357mmHg1.23573.2693MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)16367air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000289respiration rate152.3263breaths/min6.322122.7947MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)18208air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000289respiration rate142.7943breaths/min8.959129.7141MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)18210air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datablood acidity-alkalinity balance traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000064Crl:CD(SD)male99 days to 82 days5CMO:0000379blood pH7.49240.00830.0186MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)18092air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood acidity-alkalinity balance traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000064Crl:CD(SD)female99 days to 82 days7CMO:0000379blood pH7.50540.0090.0239MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)18094air oxygen content (12 %) (for 0.1 hours)
526PhysGen Lung databody massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days10CMO:0000012body weight312.9g7.423.4MMO:0000017whole body digital scaleair oxygen content (12 %) (for 14 days)60098air oxygen content (12 %) (for 14 days)
526PhysGen Lung databody massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days15CMO:0000012body weight228.3g5.521.5MMO:0000017whole body digital scaleair oxygen content (12 %) (for 14 days)60100air oxygen content (12 %) (for 14 days)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days7CMO:0000708FAPGG metabolism-surface area product25.2226ml/min/kg2.26545.9937MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours)60130air oxygen content (12 %) (for 14 days)FAPGG (0.6 mmol/l) (between 0 and 0 hours)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days10CMO:0000708FAPGG metabolism-surface area product45.0029ml/min/kg7.339323.209MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours)60132air oxygen content (12 %) (for 14 days)FAPGG (0.6 mmol/l) (between 0 and 0 hours)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days7CMO:0000711methylene blue to FAPGG metabolism-surface area product ratio0.26260.01820.0481MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58574air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days10CMO:0000711methylene blue to FAPGG metabolism-surface area product ratio0.22030.03010.0952MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58576air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
526PhysGen Lung dataerythrocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000037hematocrit56.5222%0.7312.193MMO:0000215microhematocrit tube assay with visual assessmentair oxygen content (12 %) (for 14 days)58584air oxygen content (12 %) (for 14 days)
526PhysGen Lung dataerythrocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000037hematocrit51.5556%1.43094.2928MMO:0000215microhematocrit tube assay with visual assessmentair oxygen content (12 %) (for 14 days)58586air oxygen content (12 %) (for 14 days)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days8CMO:0000710methylene blue metabolism-surface area product after auto-oxidation5.4815ml/min/kg0.3490.9871MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours)59862air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)sample resting period (for 0.1 hours)
526PhysGen Lung datapulmonary blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days10CMO:0000710methylene blue metabolism-surface area product after auto-oxidation7.649ml/min/kg0.45091.426MMO:0000152isolated perfused lung vascular effluent collectionair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours)59864air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)sample resting period (for 0.1 hours)
526PhysGen Lung dataheart right ventricle massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days10CMO:0000108heart right ventricle weight to left ventricle weight ratio0.34050.0290.0919MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)59968air oxygen content (12 %) (for 14 days)
526PhysGen Lung dataheart right ventricle massMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days10CMO:0000108heart right ventricle weight to left ventricle weight ratio0.37130.03390.1071MMO:0000157digital scale post excision weight measurementair oxygen content (12 %) (for 14 days)59970air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood globulin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0002399serum globulin levelreplaced obsolete serum globulin level term, 1/19/20162.1g/dl0.09130.2739MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39214air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood globulin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0002399serum globulin levelreplaced obsolete serum globulin level term, 1/19/20162.2778g/dl0.11520.3456MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39216air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000291mean corpuscular hemoglobin concentration32.7222g/dl0.06830.2048MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)42731air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000291mean corpuscular hemoglobin concentration32.7222g/dl0.15160.4549MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)42733air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood aspartate transaminase amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000581serum aspartate aminotransferase activity level89.7778U/l3.792511.3774MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37424air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood aspartate transaminase amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000581serum aspartate aminotransferase activity level93.2222U/l8.399425.1981MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37426air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood bilirubin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000376serum total bilirubin level0.2111mg/dl0.01110.0333MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37543air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood bilirubin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000376serum total bilirubin level0.2222mg/dl0.02220.0667MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37545air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataion homeostasis traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days8CMO:0000066plasma anion gap21.5mmol/l0.59761.6903MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37553air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataion homeostasis traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000066plasma anion gap23mmol/l0.76382.2913MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)37555air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood bicarbonate amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days8CMO:0000488serum bicarbonate level18.625mmol/l0.5651.598MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)41123air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood bicarbonate amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000488serum bicarbonate level15.8889mmol/l0.77182.3154MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)41125air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood albumin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000550serum albumin level3.7778g/dl0.05470.1641MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)41133air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood albumin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000550serum albumin level4.4889g/dl0.09780.2934MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)41135air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataleukocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000365total white blood cell count6.5556x 1000 cells/ul0.72322.1697MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39491air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataleukocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000365total white blood cell count7.5444x 1000 cells/ul0.48621.4587MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)39493air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood urea nitrogen amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days8CMO:0000587serum urea nitrogen level20.25mg/dl0.9592.7124MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39513air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood urea nitrogen amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000587serum urea nitrogen level19.4444mg/dl0.89922.6977MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39515air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood alanine transaminase amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000575serum alanine aminotransferase activity level55.4444U/l2.83888.5163MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)41600air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood alanine transaminase amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000575serum alanine aminotransferase activity level48.7778U/l4.245212.7356MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)41602air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000025red blood cell count8.8611x 10E6 cells/ul0.08020.2407MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38151air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataerythrocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000025red blood cell count8.6767x 10E6 cells/ul0.26160.7849MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38153air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood chloride amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000489serum chloride level106.3333mmol/l0.47141.4142MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38182air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood chloride amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000489serum chloride level105.5556mmol/l0.70932.1279MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38184air oxygen content (12 %) (for 14 days)
526PhysGen Lung datablood vessel distensibility traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000714fractional change in blood vessel diameter per unit change in intravascular pressure0.0529mmHg-10.0050.015MMO:0000203fluid-filled catheter with pressure transducer in isolated perfused lungair oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)58084air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
526PhysGen Lung datablood vessel distensibility traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days10CMO:0000714fractional change in blood vessel diameter per unit change in intravascular pressure0.047mmHg-10.00440.014MMO:0000203fluid-filled catheter with pressure transducer in isolated perfused lungair oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)58086air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
401PhysGen Biochemistry datalymphocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000031blood lymphocyte count5.0556x 1000 cells/ul0.67872.0362MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38216air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datalymphocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000031blood lymphocyte count5.7633x 1000 cells/ul0.38171.1452MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38218air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood sodium amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000500serum sodium level141.3333mmol/l0.5271.5811MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38238air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood sodium amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000500serum sodium level140mmol/l0.91292.7386MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)38240air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000026blood hemoglobin level18.4889g/dl0.24460.7339MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38401air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood hemoglobin amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000026blood hemoglobin level16.8556g/dl0.43431.303MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)38403air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood phosphate amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000542serum phosphate level8.9556mg/dl0.21350.6405MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36717air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood phosphate amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000542serum phosphate level8.2222mg/dl0.2210.6629MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)36719air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataeosinophil quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000033blood eosinophil count0.0267x 1000 cells/ul0.01340.0403MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)40503air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataeosinophil quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000033blood eosinophil count0.0744x 1000 cells/ul0.01570.0472MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)40505air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datamonocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000032blood monocyte count0.4011x 1000 cells/ul0.10050.3014MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)40691air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datamonocyte quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000032blood monocyte count0.3844x 1000 cells/ul0.08730.2618MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)40693air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood alkaline phosphatase amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000577serum alkaline phosphatase activity level246.6667U/l20.244360.733MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42348air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood alkaline phosphatase amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000577serum alkaline phosphatase activity level162.6667U/l11.458934.3766MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42350air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataneutrophil quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000030blood neutrophil count1.0722x 1000 cells/ul0.1560.468MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)42368air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry dataneutrophil quantityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000030blood neutrophil count1.3211x 1000 cells/ul0.210.6299MMO:0000146automated blood cell counting methodair oxygen content (12 %) (for 14 days)42370air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood creatinine amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000537plasma creatinine level0.2889mg/dl0.020.0601MMO:0000354automated plasma creatinine analysisair oxygen content (12 %) (for 14 days)40799air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood creatinine amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000537plasma creatinine level0.3222mg/dl0.02220.0667MMO:0000354automated plasma creatinine analysisair oxygen content (12 %) (for 14 days)40801air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood calcium amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days8CMO:0000503serum calcium level9.6mg/dl0.12820.3625MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42522air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood calcium amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000503serum calcium level9.7mg/dl0.08660.2598MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)42524air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood potassium amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male91 days to 77 days9CMO:0000495serum potassium level4.9889mmol/l0.13590.4076MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39094air oxygen content (12 %) (for 14 days)
401PhysGen Biochemistry datablood potassium amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female91 days to 77 days9CMO:0000495serum potassium level4.4333mmol/l0.13120.3937MMO:0000169standard blood chemistry panelair oxygen content (12 %) (for 14 days)39096air oxygen content (12 %) (for 14 days)
461PhysGen Cardiac dataarterial blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000749percent change in arterial blood flow ratepost-ischemic value/pre-ischemic value x 100%63.538%2.82198.9236MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47884air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataarterial blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000749percent change in arterial blood flow ratepost-ischemic value/pre-ischemic value x 100%67.8409%7.404523.415MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47886air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000006left ventricular diastolic blood pressure5.729mmHg0.11120.3518MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48008air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days9CMO:0000006left ventricular diastolic blood pressure5.3022mmHg0.11850.3555MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48010air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart muscle contractility traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000663time to onset of heart contraction831.134s52.0047164.4532MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)48120air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart muscle contractility traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000663time to onset of heart contraction870.375s51.092161.5671MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)48122air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
461PhysGen Cardiac dataheart lactate dehydrogenase activityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days9CMO:0000775heart effluent lactate dehydrogenase activity level normalized to heart weight0.4454IU/g0.2460.7381MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48379air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart lactate dehydrogenase activityMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days9CMO:0000775heart effluent lactate dehydrogenase activity level normalized to heart weight0.2045IU/g0.04950.1486MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48381air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000532percent change in tidal volume101.901%3.470112.5117MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)53613air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000531percent change in respiration rate137.4055%8.770129.0872MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)54519air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000531percent change in respiration rate131.3228%6.813124.565MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)54526air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory databody temperature traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000015body temperature37.4538degrees C0.09650.3479MMO:0000034digital rectal thermometryair oxygen content (12 %) (for 0.1 hours)19992air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory databody temperature traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000015body temperature37.3818degrees C0.1470.4875MMO:0000034digital rectal thermometryair oxygen content (12 %) (for 0.1 hours)19994air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000531percent change in respiration rate138.2795%7.691325.5091MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)53595air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000531percent change in respiration rate128.2398%4.57616.4991MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)53602air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000532percent change in tidal volume106.3137%3.844412.7504MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)53606air oxygen content (12 %) (between 0 and 0.1 hours)
461PhysGen Cardiac dataarterial blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000198arterial blood flow rate9.37ml/min/g0.51091.6156MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46176air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataarterial blood flow traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000198arterial blood flow rate12.695ml/min/g3.582811.3297MMO:0000114isolated perfused heart effluent collectionair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46178air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000751percent change in left ventricular developed pressurepost-ischemic value/pre-ischemic value x 100%27.4644%7.858424.8505MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47522air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000751percent change in left ventricular developed pressurepost-ischemic value/pre-ischemic value x 100%25.5081%8.581627.1375MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47524air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000002heart rate332.002beats/min62.3887197.2904MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46501air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days10CMO:0000002heart rate245.027beats/min30.089695.1516MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46503air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000018left ventricular developed pressure130.924mmHg5.553617.5619MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47666air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000018left ventricular developed pressure34.855mmHg9.358229.5934MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45903air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days8CMO:0000018left ventricular developed pressure43.9112mmHg11.545932.6566MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45905air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male63 days to 49 days10CMO:0000006left ventricular diastolic blood pressure56.353mmHg5.114116.1722MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45933air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days9CMO:0000006left ventricular diastolic blood pressure59.3944mmHg4.848214.5446MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45935air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
461PhysGen Cardiac dataheart left ventricular blood pressure traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female63 days to 49 days9CMO:0000018left ventricular developed pressure141.9956mmHg4.412113.2364MMO:0000029balloon tipped catheter with pressure transducer in isolated perfused heartair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47668air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
381PhysGen Respiratory databody temperature traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000699absolute change in body temperature-0.0769degrees C0.19020.6858MMO:0000034digital rectal thermometryair oxygen content (12 %) (for 0.1 hours)19156air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory databody temperature traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000699absolute change in body temperature-0.6273degrees C0.1950.6467MMO:0000034digital rectal thermometryair oxygen content (12 %) (for 0.1 hours)19158air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood oxygen amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days5CMO:0000299absolute change in partial pressure of blood oxygen-44.6mmHg4.40679.8537MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)20688air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood oxygen amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days7CMO:0000299absolute change in partial pressure of blood oxygen-51.5429mmHg2.20075.8225MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)20690air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood oxygen amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days5CMO:0000381partial pressure of blood oxygen51.86mmHg0.34580.7733MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)17008air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood oxygen amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days7CMO:0000381partial pressure of blood oxygen54.5mmHg1.37913.6487MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)17010air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000222tidal volume0.3466ml0.03080.111MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)16034air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000222tidal volume0.3039ml0.02030.0674MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)16036air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000222tidal volume0.3644ml0.02890.1044MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)14010air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000222tidal volume0.3191ml0.02290.076MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)14012air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days7CMO:0000002heart rate389.5857beats/min19.896852.6419MMO:0000013vascular fluid filled catheterair oxygen content (12 %) (for 0.1 hours)16124air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory dataheart pumping traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days9CMO:0000002heart rate417.1844beats/min29.611688.8348MMO:0000013vascular fluid filled catheterair oxygen content (12 %) (for 0.1 hours)16126air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood acidity-alkalinity balance traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days5CMO:0000300absolute change in blood pH0.04360.00330.0074MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)16667air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood acidity-alkalinity balance traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days7CMO:0000300absolute change in blood pH0.07590.01430.038MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)16669air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000132minute ventilation54.7376ml/min3.921714.1397MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)19718air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000132minute ventilation45.2246ml/min3.803112.6133MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0 and 0.1 hours)19720air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datablood carbon dioxide amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days5CMO:0000298absolute change in partial pressure of blood carbon dioxide-4.05mmHg0.58351.3048MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)20982air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datablood carbon dioxide amountMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days7CMO:0000298absolute change in partial pressure of blood carbon dioxide-6.9143mmHg1.15153.0467MMO:0000036automated blood gas analysis using a Bayer analyzerair oxygen content (12 %) (for 0.1 hours)20984air oxygen content (12 %) (for 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000289respiration rate149.871breaths/min6.132922.1126MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)17558air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datarespiratory function traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000289respiration rate143.3767breaths/min7.281524.1499MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)17560air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000288percent change in ventilation%change=VE during7-9 min hypoxia/control during standard conditions123.4903%5.266718.9893MMO:0000022stop flow air displacement plethysmographycontrolled sodium content diet (0 %) then air oxygen content (12 %) (between 0.1 and 0.1 hours)17335controlled sodium content diet (0 %) air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000288percent change in ventilation%change=VE during7-9 min hypoxia/control during standard conditions139.275%7.589725.1723MMO:0000022stop flow air displacement plethysmographycontrolled sodium content diet (0 %) then air oxygen content (12 %) (between 0.1 and 0.1 hours)17337controlled sodium content diet (0 %) air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000132minute ventilation51.8123ml/min4.419215.9337MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)18964air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000132minute ventilation43.5092ml/min3.511711.647MMO:0000022stop flow air displacement plethysmographyair oxygen content (12 %) (between 0.1 and 0.1 hours)18966air oxygen content (12 %) (between 0.1 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)male99 days to 82 days13CMO:0000288percent change in ventilation%change=VE during 2-3 min hypoxia/control during standard conditions132.6158%6.271622.6126MMO:0000022stop flow air displacement plethysmographycontrolled sodium content diet (0 %) then air oxygen content (12 %) (between 0 and 0.1 hours)19302controlled sodium content diet (0 %) air oxygen content (12 %) (between 0 and 0.1 hours)
381PhysGen Respiratory datapulmonary ventilation traitMoms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and HarlanRS:0000064Crl:CD(SD)female99 days to 82 days11CMO:0000288percent change in ventilation%change=VE during 2-3 min hypoxia/control during standard conditions144.6677%8.047726.6913MMO:0000022stop flow air displacement plethysmographycontrolled sodium content diet (0 %) then air oxygen content (12 %) (between 0 and 0.1 hours)19304controlled sodium content diet (0 %) air oxygen content (12 %) (between 0 and 0.1 hours)