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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1Condition 2aCondition 2bCondition 3Condition 4
10lung dry weight to body weight ratioCrl:CD(SD)male1.0326g/kgair oxygen content (12 %) (for 14 days)57575air oxygen content (12 %) (for 14 days)
15lung dry weight to body weight ratioCrl:CD(SD)female1.3583g/kgair oxygen content (12 %) (for 14 days)57577air oxygen content (12 %) (for 14 days)
9calculated pulmonary vascular resistance normalized to body weightCrl:CD(SD)male0.1465mmHg x min x kg x ml-1air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)57683air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
10calculated pulmonary vascular resistance normalized to body weightCrl:CD(SD)female0.1343mmHg x min x kg x ml-1air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)57685air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
7dose of methacholine at which pulmonary conductance is half its pretreatment valueCrl:CD(SD)male2.8517mg/kgair oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)57765air oxygen content (12 %) (for 14 days)methacholine (0-11.06 mg/kg) drug dose time series (for 0.2 hours)
8dose of methacholine at which pulmonary conductance is half its pretreatment valueCrl:CD(SD)female4.1478mg/kgair oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)57767air oxygen content (12 %) (for 14 days)methacholine (0-11.06 mg/kg) drug dose time series (for 0.2 hours)
10heart wet weightCrl:CD(SD)male1.269gair oxygen content (12 %) (for 14 days)45030air oxygen content (12 %) (for 14 days)
10heart wet weightCrl:CD(SD)female1.034gair oxygen content (12 %) (for 14 days)45032air oxygen content (12 %) (for 14 days)
10arterial blood flow rateCrl:CD(SD)male14.758ml/min/gair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)45083air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
9arterial blood flow rateCrl:CD(SD)female14.6111ml/min/gair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)45085air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
10time to peak heart contractionCrl:CD(SD)male1139.633sair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)45103air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
10time to peak heart contractionCrl:CD(SD)female1139.166sair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)45105air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
10left ventricular systolic blood pressureCrl:CD(SD)male136.653mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)49802air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
10left ventricular systolic blood pressureCrl:CD(SD)female148.93mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)49804air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
10heart rateCrl:CD(SD)male257.167beats/minair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)49972air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
10heart rateCrl:CD(SD)female250.691beats/minair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)49974air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
10body weightCrl:CD(SD)male251.5gair oxygen content (12 %) (for 14 days)50081air oxygen content (12 %) (for 14 days)
10body weightCrl:CD(SD)female190.4gair oxygen content (12 %) (for 14 days)50083air oxygen content (12 %) (for 14 days)
10heart contraction pressureCrl:CD(SD)male49.4mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)49589air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
10heart contraction pressureCrl:CD(SD)female47.1mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)49591air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
10percent change in left ventricular systolic blood pressureCrl:CD(SD)male67.5065%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49653air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10percent change in left ventricular systolic blood pressureCrl:CD(SD)female58.7035%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49655air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10heart left ventricle infarction weight to total heart left ventricle weight ratioCrl:CD(SD)male9.359%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours)49030air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 3 hours)
10heart left ventricle infarction weight to total heart left ventricle weight ratioCrl:CD(SD)female6.648%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours)49032air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 3 hours)
10heart weight to body weight ratioCrl:CD(SD)male5.044g/kgair oxygen content (12 %) (for 14 days)49145air oxygen content (12 %) (for 14 days)
10heart weight to body weight ratioCrl:CD(SD)female5.458g/kgair oxygen content (12 %) (for 14 days)49147air oxygen content (12 %) (for 14 days)
10percent change in heart rateCrl:CD(SD)male131.5896%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49262air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10percent change in heart rateCrl:CD(SD)female96.6774%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49264air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10left ventricular systolic blood pressureCrl:CD(SD)male91.208mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49274air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
9left ventricular systolic blood pressureCrl:CD(SD)female95.7611mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)49276air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
7mean arterial blood pressureCrl:CD(SD)male119.3986mmHgair oxygen content (12 %) (for 0.1 hours)13878air oxygen content (12 %) (for 0.1 hours)
9mean arterial blood pressureCrl:CD(SD)female109.2544mmHgair oxygen content (12 %) (for 0.1 hours)13880air oxygen content (12 %) (for 0.1 hours)
11percent change in tidal volumeCrl:CD(SD)female101.4774%air oxygen content (12 %) (between 0.1 and 0.1 hours)54191air oxygen content (12 %) (between 0.1 and 0.1 hours)
13percent change in tidal volumeCrl:CD(SD)male96.1166%air oxygen content (12 %) (between 0.1 and 0.1 hours)54198air oxygen content (12 %) (between 0.1 and 0.1 hours)
9serum total cholesterol levelCrl:CD(SD)male73.2222mg/dlair oxygen content (12 %) (for 14 days)36464air oxygen content (12 %) (for 14 days)
9serum total cholesterol levelCrl:CD(SD)female62.3333mg/dlair oxygen content (12 %) (for 14 days)36466air oxygen content (12 %) (for 14 days)
9serum total protein levelCrl:CD(SD)male5.8778g/dlair oxygen content (12 %) (for 14 days)36263air oxygen content (12 %) (for 14 days)
9serum total protein levelCrl:CD(SD)female6.7667g/dlair oxygen content (12 %) (for 14 days)36265air oxygen content (12 %) (for 14 days)
9mean corpuscular volumeCrl:CD(SD)male63.7778flair oxygen content (12 %) (for 14 days)36287air oxygen content (12 %) (for 14 days)
9mean corpuscular volumeCrl:CD(SD)female59.4889flair oxygen content (12 %) (for 14 days)36289air oxygen content (12 %) (for 14 days)
9serum glucose levelCrl:CD(SD)male166.6667mg/dlair oxygen content (12 %) (for 14 days)36321air oxygen content (12 %) (for 14 days)
9serum glucose levelCrl:CD(SD)female156.5556mg/dlair oxygen content (12 %) (for 14 days)36323air oxygen content (12 %) (for 14 days)
9hematocritCrl:CD(SD)male56.5222%air oxygen content (12 %) (for 14 days)36346air oxygen content (12 %) (for 14 days)
9hematocritCrl:CD(SD)female51.5556%air oxygen content (12 %) (for 14 days)36348air oxygen content (12 %) (for 14 days)
9mean corpuscular hemoglobinCrl:CD(SD)male20.8556pgair oxygen content (12 %) (for 14 days)36356air oxygen content (12 %) (for 14 days)
9mean corpuscular hemoglobinCrl:CD(SD)female19.4667pgair oxygen content (12 %) (for 14 days)36358air oxygen content (12 %) (for 14 days)
8methylene blue metabolism-surface area product without auto-oxidationCrl:CD(SD)male6.2756ml/min/kgair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58836air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
10methylene blue metabolism-surface area product without auto-oxidationCrl:CD(SD)female8.5929ml/min/kgair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58838air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
5partial pressure of blood carbon dioxide (Pco2)Crl:CD(SD)male28.81mmHgair oxygen content (12 %) (for 0.1 hours)16365air oxygen content (12 %) (for 0.1 hours)
7partial pressure of blood carbon dioxide (Pco2)Crl:CD(SD)female26.5357mmHgair oxygen content (12 %) (for 0.1 hours)16367air oxygen content (12 %) (for 0.1 hours)
13respiration rateCrl:CD(SD)male152.3263breaths/minair oxygen content (12 %) (between 0 and 0.1 hours)18208air oxygen content (12 %) (between 0 and 0.1 hours)
11respiration rateCrl:CD(SD)female142.7943breaths/minair oxygen content (12 %) (between 0 and 0.1 hours)18210air oxygen content (12 %) (between 0 and 0.1 hours)
5blood pHCrl:CD(SD)male7.4924air oxygen content (12 %) (for 0.1 hours)18092air oxygen content (12 %) (for 0.1 hours)
7blood pHCrl:CD(SD)female7.5054air oxygen content (12 %) (for 0.1 hours)18094air oxygen content (12 %) (for 0.1 hours)
10body weightCrl:CD(SD)male312.9gair oxygen content (12 %) (for 14 days)60098air oxygen content (12 %) (for 14 days)
15body weightCrl:CD(SD)female228.3gair oxygen content (12 %) (for 14 days)60100air oxygen content (12 %) (for 14 days)
7FAPGG metabolism-surface area productCrl:CD(SD)male25.2226ml/min/kgair oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours)60130air oxygen content (12 %) (for 14 days)FAPGG (0.6 mmol/l) (between 0 and 0 hours)
10FAPGG metabolism-surface area productCrl:CD(SD)female45.0029ml/min/kgair oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours)60132air oxygen content (12 %) (for 14 days)FAPGG (0.6 mmol/l) (between 0 and 0 hours)
7methylene blue to FAPGG metabolism-surface area product ratioCrl:CD(SD)male0.2626air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58574air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
10methylene blue to FAPGG metabolism-surface area product ratioCrl:CD(SD)female0.2203air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours)58576air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)
9hematocritCrl:CD(SD)male56.5222%air oxygen content (12 %) (for 14 days)58584air oxygen content (12 %) (for 14 days)
9hematocritCrl:CD(SD)female51.5556%air oxygen content (12 %) (for 14 days)58586air oxygen content (12 %) (for 14 days)
8methylene blue metabolism-surface area product after auto-oxidationCrl:CD(SD)male5.4815ml/min/kgair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours)59862air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)sample resting period (for 0.1 hours)
10methylene blue metabolism-surface area product after auto-oxidationCrl:CD(SD)female7.649ml/min/kgair oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours)59864air oxygen content (12 %) (for 14 days)methylene blue (10 umol/l) (between 0 and 0 hours)sample resting period (for 0.1 hours)
10heart right ventricle weight to left ventricle weight ratioCrl:CD(SD)male0.3405air oxygen content (12 %) (for 14 days)59968air oxygen content (12 %) (for 14 days)
10heart right ventricle weight to left ventricle weight ratioCrl:CD(SD)female0.3713air oxygen content (12 %) (for 14 days)59970air oxygen content (12 %) (for 14 days)
9serum globulin levelCrl:CD(SD)male2.1g/dlair oxygen content (12 %) (for 14 days)39214air oxygen content (12 %) (for 14 days)
9serum globulin levelCrl:CD(SD)female2.2778g/dlair oxygen content (12 %) (for 14 days)39216air oxygen content (12 %) (for 14 days)
9mean corpuscular hemoglobin concentrationCrl:CD(SD)male32.7222g/dlair oxygen content (12 %) (for 14 days)42731air oxygen content (12 %) (for 14 days)
9mean corpuscular hemoglobin concentrationCrl:CD(SD)female32.7222g/dlair oxygen content (12 %) (for 14 days)42733air oxygen content (12 %) (for 14 days)
9serum aspartate aminotransferase activity levelCrl:CD(SD)male89.7778U/lair oxygen content (12 %) (for 14 days)37424air oxygen content (12 %) (for 14 days)
9serum aspartate aminotransferase activity levelCrl:CD(SD)female93.2222U/lair oxygen content (12 %) (for 14 days)37426air oxygen content (12 %) (for 14 days)
9serum total bilirubin levelCrl:CD(SD)male0.2111mg/dlair oxygen content (12 %) (for 14 days)37543air oxygen content (12 %) (for 14 days)
9serum total bilirubin levelCrl:CD(SD)female0.2222mg/dlair oxygen content (12 %) (for 14 days)37545air oxygen content (12 %) (for 14 days)
8plasma anion gapCrl:CD(SD)male21.5mmol/lair oxygen content (12 %) (for 14 days)37553air oxygen content (12 %) (for 14 days)
9plasma anion gapCrl:CD(SD)female23mmol/lair oxygen content (12 %) (for 14 days)37555air oxygen content (12 %) (for 14 days)
8serum bicarbonate levelCrl:CD(SD)male18.625mmol/lair oxygen content (12 %) (for 14 days)41123air oxygen content (12 %) (for 14 days)
9serum bicarbonate levelCrl:CD(SD)female15.8889mmol/lair oxygen content (12 %) (for 14 days)41125air oxygen content (12 %) (for 14 days)
9serum albumin levelCrl:CD(SD)male3.7778g/dlair oxygen content (12 %) (for 14 days)41133air oxygen content (12 %) (for 14 days)
9serum albumin levelCrl:CD(SD)female4.4889g/dlair oxygen content (12 %) (for 14 days)41135air oxygen content (12 %) (for 14 days)
9total white blood cell countCrl:CD(SD)male6.5556x 1000 cells/ulair oxygen content (12 %) (for 14 days)39491air oxygen content (12 %) (for 14 days)
9total white blood cell countCrl:CD(SD)female7.5444x 1000 cells/ulair oxygen content (12 %) (for 14 days)39493air oxygen content (12 %) (for 14 days)
8serum urea nitrogen levelCrl:CD(SD)male20.25mg/dlair oxygen content (12 %) (for 14 days)39513air oxygen content (12 %) (for 14 days)
9serum urea nitrogen levelCrl:CD(SD)female19.4444mg/dlair oxygen content (12 %) (for 14 days)39515air oxygen content (12 %) (for 14 days)
9serum alanine aminotransferase activity levelCrl:CD(SD)male55.4444U/lair oxygen content (12 %) (for 14 days)41600air oxygen content (12 %) (for 14 days)
9serum alanine aminotransferase activity levelCrl:CD(SD)female48.7778U/lair oxygen content (12 %) (for 14 days)41602air oxygen content (12 %) (for 14 days)
9red blood cell countCrl:CD(SD)male8.8611x 10E6 cells/ulair oxygen content (12 %) (for 14 days)38151air oxygen content (12 %) (for 14 days)
9red blood cell countCrl:CD(SD)female8.6767x 10E6 cells/ulair oxygen content (12 %) (for 14 days)38153air oxygen content (12 %) (for 14 days)
9serum chloride levelCrl:CD(SD)male106.3333mmol/lair oxygen content (12 %) (for 14 days)38182air oxygen content (12 %) (for 14 days)
9serum chloride levelCrl:CD(SD)female105.5556mmol/lair oxygen content (12 %) (for 14 days)38184air oxygen content (12 %) (for 14 days)
9fractional change in blood vessel diameter per unit change in intravascular pressureCrl:CD(SD)male0.0529mmHg-1air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)58084air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
10fractional change in blood vessel diameter per unit change in intravascular pressureCrl:CD(SD)female0.047mmHg-1air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours)58086air oxygen content (12 %) (for 14 days)Kreb's solution perfusate (between 0.2 and 0.2 hours)
9blood lymphocyte countCrl:CD(SD)male5.0556x 1000 cells/ulair oxygen content (12 %) (for 14 days)38216air oxygen content (12 %) (for 14 days)
9blood lymphocyte countCrl:CD(SD)female5.7633x 1000 cells/ulair oxygen content (12 %) (for 14 days)38218air oxygen content (12 %) (for 14 days)
9serum sodium levelCrl:CD(SD)male141.3333mmol/lair oxygen content (12 %) (for 14 days)38238air oxygen content (12 %) (for 14 days)
9serum sodium levelCrl:CD(SD)female140mmol/lair oxygen content (12 %) (for 14 days)38240air oxygen content (12 %) (for 14 days)
9blood hemoglobin levelCrl:CD(SD)male18.4889g/dlair oxygen content (12 %) (for 14 days)38401air oxygen content (12 %) (for 14 days)
9blood hemoglobin levelCrl:CD(SD)female16.8556g/dlair oxygen content (12 %) (for 14 days)38403air oxygen content (12 %) (for 14 days)
9serum phosphate levelCrl:CD(SD)male8.9556mg/dlair oxygen content (12 %) (for 14 days)36717air oxygen content (12 %) (for 14 days)
9serum phosphate levelCrl:CD(SD)female8.2222mg/dlair oxygen content (12 %) (for 14 days)36719air oxygen content (12 %) (for 14 days)
9blood eosinophil countCrl:CD(SD)male0.0267x 1000 cells/ulair oxygen content (12 %) (for 14 days)40503air oxygen content (12 %) (for 14 days)
9blood eosinophil countCrl:CD(SD)female0.0744x 1000 cells/ulair oxygen content (12 %) (for 14 days)40505air oxygen content (12 %) (for 14 days)
9blood monocyte countCrl:CD(SD)male0.4011x 1000 cells/ulair oxygen content (12 %) (for 14 days)40691air oxygen content (12 %) (for 14 days)
9blood monocyte countCrl:CD(SD)female0.3844x 1000 cells/ulair oxygen content (12 %) (for 14 days)40693air oxygen content (12 %) (for 14 days)
9serum alkaline phosphatase activity levelCrl:CD(SD)male246.6667U/lair oxygen content (12 %) (for 14 days)42348air oxygen content (12 %) (for 14 days)
9serum alkaline phosphatase activity levelCrl:CD(SD)female162.6667U/lair oxygen content (12 %) (for 14 days)42350air oxygen content (12 %) (for 14 days)
9blood neutrophil countCrl:CD(SD)male1.0722x 1000 cells/ulair oxygen content (12 %) (for 14 days)42368air oxygen content (12 %) (for 14 days)
9blood neutrophil countCrl:CD(SD)female1.3211x 1000 cells/ulair oxygen content (12 %) (for 14 days)42370air oxygen content (12 %) (for 14 days)
9plasma creatinine levelCrl:CD(SD)male0.2889mg/dlair oxygen content (12 %) (for 14 days)40799air oxygen content (12 %) (for 14 days)
9plasma creatinine levelCrl:CD(SD)female0.3222mg/dlair oxygen content (12 %) (for 14 days)40801air oxygen content (12 %) (for 14 days)
8serum calcium levelCrl:CD(SD)male9.6mg/dlair oxygen content (12 %) (for 14 days)42522air oxygen content (12 %) (for 14 days)
9serum calcium levelCrl:CD(SD)female9.7mg/dlair oxygen content (12 %) (for 14 days)42524air oxygen content (12 %) (for 14 days)
9serum potassium levelCrl:CD(SD)male4.9889mmol/lair oxygen content (12 %) (for 14 days)39094air oxygen content (12 %) (for 14 days)
9serum potassium levelCrl:CD(SD)female4.4333mmol/lair oxygen content (12 %) (for 14 days)39096air oxygen content (12 %) (for 14 days)
10percent change in arterial blood flow rateCrl:CD(SD)male63.538%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47884air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10percent change in arterial blood flow rateCrl:CD(SD)female67.8409%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47886air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10left ventricular diastolic blood pressureCrl:CD(SD)male5.729mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48008air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
9left ventricular diastolic blood pressureCrl:CD(SD)female5.3022mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48010air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
10time to onset of heart contractionCrl:CD(SD)male831.134sair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)48120air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
10time to onset of heart contractionCrl:CD(SD)female870.375sair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours)48122air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)
9heart effluent lactate dehydrogenase activity level normalized to heart weightCrl:CD(SD)male0.4454IU/gair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48379air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
9heart effluent lactate dehydrogenase activity level normalized to heart weightCrl:CD(SD)female0.2045IU/gair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)48381air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
13percent change in tidal volumeCrl:CD(SD)male101.901%air oxygen content (12 %) (between 0 and 0.1 hours)53613air oxygen content (12 %) (between 0 and 0.1 hours)
11percent change in respiration rateCrl:CD(SD)female137.4055%air oxygen content (12 %) (between 0 and 0.1 hours)54519air oxygen content (12 %) (between 0 and 0.1 hours)
13percent change in respiration rateCrl:CD(SD)male131.3228%air oxygen content (12 %) (between 0 and 0.1 hours)54526air oxygen content (12 %) (between 0 and 0.1 hours)
13body temperatureCrl:CD(SD)male37.4538degrees Cair oxygen content (12 %) (for 0.1 hours)19992air oxygen content (12 %) (for 0.1 hours)
11body temperatureCrl:CD(SD)female37.3818degrees Cair oxygen content (12 %) (for 0.1 hours)19994air oxygen content (12 %) (for 0.1 hours)
11percent change in respiration rateCrl:CD(SD)female138.2795%air oxygen content (12 %) (between 0.1 and 0.1 hours)53595air oxygen content (12 %) (between 0.1 and 0.1 hours)
13percent change in respiration rateCrl:CD(SD)male128.2398%air oxygen content (12 %) (between 0.1 and 0.1 hours)53602air oxygen content (12 %) (between 0.1 and 0.1 hours)
11percent change in tidal volumeCrl:CD(SD)female106.3137%air oxygen content (12 %) (between 0 and 0.1 hours)53606air oxygen content (12 %) (between 0 and 0.1 hours)
10arterial blood flow rateCrl:CD(SD)male9.37ml/min/gair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46176air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10arterial blood flow rateCrl:CD(SD)female12.695ml/min/gair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46178air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10percent change in left ventricular developed pressureCrl:CD(SD)male27.4644%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47522air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10percent change in left ventricular developed pressureCrl:CD(SD)female25.5081%air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)47524air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10heart rateCrl:CD(SD)male332.002beats/minair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46501air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10heart rateCrl:CD(SD)female245.027beats/minair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)46503air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10left ventricular developed pressureCrl:CD(SD)male130.924mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47666air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
10left ventricular developed pressureCrl:CD(SD)male34.855mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45903air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
8left ventricular developed pressureCrl:CD(SD)female43.9112mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45905air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
10left ventricular diastolic blood pressureCrl:CD(SD)male56.353mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45933air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
9left ventricular diastolic blood pressureCrl:CD(SD)female59.3944mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours)45935air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)perfusate suspended (for 0.4 hours)controlled oxygen content Kreb's solution perfusate (for 0.7 hours)
9left ventricular developed pressureCrl:CD(SD)female141.9956mmHgair oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours)47668air oxygen content (12 %) (for 14 days)controlled oxygen content Kreb's solution perfusate (for 0.5 hours)
13absolute change in body temperatureCrl:CD(SD)male-0.0769degrees Cair oxygen content (12 %) (for 0.1 hours)19156air oxygen content (12 %) (for 0.1 hours)
11absolute change in body temperatureCrl:CD(SD)female-0.6273degrees Cair oxygen content (12 %) (for 0.1 hours)19158air oxygen content (12 %) (for 0.1 hours)
5absolute change in partial pressure of blood oxygenCrl:CD(SD)male-44.6mmHgair oxygen content (12 %) (for 0.1 hours)20688air oxygen content (12 %) (for 0.1 hours)
7absolute change in partial pressure of blood oxygenCrl:CD(SD)female-51.5429mmHgair oxygen content (12 %) (for 0.1 hours)20690air oxygen content (12 %) (for 0.1 hours)
5partial pressure of blood oxygenCrl:CD(SD)male51.86mmHgair oxygen content (12 %) (for 0.1 hours)17008air oxygen content (12 %) (for 0.1 hours)
7partial pressure of blood oxygenCrl:CD(SD)female54.5mmHgair oxygen content (12 %) (for 0.1 hours)17010air oxygen content (12 %) (for 0.1 hours)
13tidal volumeCrl:CD(SD)male0.3466mlair oxygen content (12 %) (between 0.1 and 0.1 hours)16034air oxygen content (12 %) (between 0.1 and 0.1 hours)
11tidal volumeCrl:CD(SD)female0.3039mlair oxygen content (12 %) (between 0.1 and 0.1 hours)16036air oxygen content (12 %) (between 0.1 and 0.1 hours)
13tidal volumeCrl:CD(SD)male0.3644mlair oxygen content (12 %) (between 0 and 0.1 hours)14010air oxygen content (12 %) (between 0 and 0.1 hours)
11tidal volumeCrl:CD(SD)female0.3191mlair oxygen content (12 %) (between 0 and 0.1 hours)14012air oxygen content (12 %) (between 0 and 0.1 hours)
7heart rateCrl:CD(SD)male389.5857beats/minair oxygen content (12 %) (for 0.1 hours)16124air oxygen content (12 %) (for 0.1 hours)
9heart rateCrl:CD(SD)female417.1844beats/minair oxygen content (12 %) (for 0.1 hours)16126air oxygen content (12 %) (for 0.1 hours)
5absolute change in blood pHCrl:CD(SD)male0.0436air oxygen content (12 %) (for 0.1 hours)16667air oxygen content (12 %) (for 0.1 hours)
7absolute change in blood pHCrl:CD(SD)female0.0759air oxygen content (12 %) (for 0.1 hours)16669air oxygen content (12 %) (for 0.1 hours)
13minute ventilationCrl:CD(SD)male54.7376ml/minair oxygen content (12 %) (between 0 and 0.1 hours)19718air oxygen content (12 %) (between 0 and 0.1 hours)
11minute ventilationCrl:CD(SD)female45.2246ml/minair oxygen content (12 %) (between 0 and 0.1 hours)19720air oxygen content (12 %) (between 0 and 0.1 hours)
5absolute change in partial pressure of blood carbon dioxideCrl:CD(SD)male-4.05mmHgair oxygen content (12 %) (for 0.1 hours)20982air oxygen content (12 %) (for 0.1 hours)
7absolute change in partial pressure of blood carbon dioxideCrl:CD(SD)female-6.9143mmHgair oxygen content (12 %) (for 0.1 hours)20984air oxygen content (12 %) (for 0.1 hours)
13respiration rateCrl:CD(SD)male149.871breaths/minair oxygen content (12 %) (between 0.1 and 0.1 hours)17558air oxygen content (12 %) (between 0.1 and 0.1 hours)
11respiration rateCrl:CD(SD)female143.3767breaths/minair oxygen content (12 %) (between 0.1 and 0.1 hours)17560air oxygen content (12 %) (between 0.1 and 0.1 hours)
13percent change in ventilationCrl:CD(SD)male123.4903%controlled sodium content diet (0 %) then air oxygen content (12 %) (between 0.1 and 0.1 hours)17335controlled sodium content diet (0 %) air oxygen content (12 %) (between 0.1 and 0.1 hours)
11percent change in ventilationCrl:CD(SD)female139.275%controlled sodium content diet (0 %) then air oxygen content (12 %) (between 0.1 and 0.1 hours)17337controlled sodium content diet (0 %) air oxygen content (12 %) (between 0.1 and 0.1 hours)
13minute ventilationCrl:CD(SD)male51.8123ml/minair oxygen content (12 %) (between 0.1 and 0.1 hours)18964air oxygen content (12 %) (between 0.1 and 0.1 hours)
11minute ventilationCrl:CD(SD)female43.5092ml/minair oxygen content (12 %) (between 0.1 and 0.1 hours)18966air oxygen content (12 %) (between 0.1 and 0.1 hours)
13percent change in ventilationCrl:CD(SD)male132.6158%controlled sodium content diet (0 %) then air oxygen content (12 %) (between 0 and 0.1 hours)19302controlled sodium content diet (0 %) air oxygen content (12 %) (between 0 and 0.1 hours)
11percent change in ventilationCrl:CD(SD)female144.6677%controlled sodium content diet (0 %) then air oxygen content (12 %) (between 0 and 0.1 hours)19304controlled sodium content diet (0 %) air oxygen content (12 %) (between 0 and 0.1 hours)