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Strain
Phenotype
Conditions
Study
Experiment Name
Sex
Age
# of Animals
Value
Units
SEM
SD
Individual Records
Method
Method Duration
Post Insult Time Value
Experiment Notes
Record ID
Study ID
WKY/NCrl
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
female
70.0 days-84.0 days
9
-8.34
null
0.07
0.21
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
55118
522
WKY/NCrl
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
salidroside (40 mg/kg) (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
-8.04
null
0.04
0.12
wire myography
0.0
103595
2827
WKY/NCrl
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
male
70.0 days-84.0 days
14
-7.97
null
0.09
0.35
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
55111
522
WKY/NCrl
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
vehicle control condition (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
-8.15
null
0.09
0.24
wire myography
0.0
103610
2827
WKY/NCrl
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
vehicle control condition (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
-8.06
null
0.05
0.13
wire myography
0.0
103594
2827
WKY/NCrl
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
female
70.0 days-84.0 days
12
-8.53
null
0.12
0.42
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
55351
522
WKY/NCrl
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
salidroside (40 mg/kg) (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
-8.21
null
0.07
0.19
wire myography
0.0
103611
2827
WKY/NCrl
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
male
70.0 days-84.0 days
15
-7.84
null
0.08
0.31
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
55344
522