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PhenoMiner Database Result        View data table  |  Download data table  |  View expanded data table        


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Rat Strains

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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1Condition 2Condition 3aCondition 3b
6renal vascular resistanceWKYmale8.8mmHg/ml/minunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days)99964unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)bosentan (100 mg/kg/d) (for 14 days)
8renal vascular resistanceWKYmale9.2mmHg/ml/minunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days)99963unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)
8renal vascular resistanceWKYmale8.8mmHg/ml/minunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days)99962unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 14 days)
8renal vascular resistanceWKYmale9mmHg/ml/minunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition99961unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) vehicle control condition
7renal vascular resistanceWKYmale10mmHg/ml/minunilateral nephrectomy (for 28 days) then vehicle control condition99960unilateral nephrectomy (for 28 days)vehicle control condition
16renal vascular resistanceWKYmale6.8mmHg/ml/minunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days)99999unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 154 days)bosentan (100 mg/kg/d) (for 154 days)
16renal vascular resistanceWKYmale7.1mmHg/ml/minunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days)99998unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 154 days)
17renal vascular resistanceWKYmale6.6mmHg/ml/minunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days)99997unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 154 days)
17renal vascular resistanceWKYmale16.7mmHg/ml/minunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition99996unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) vehicle control condition
11renal vascular resistanceWKYmale6.3mmHg/ml/minunilateral nephrectomy (for 28 days) then vehicle control condition99995unilateral nephrectomy (for 28 days)vehicle control condition
6renal plasma flow to body weight ratioWKYmale2.42ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days)99954unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)bosentan (100 mg/kg/d) (for 14 days)
8renal plasma flow to body weight ratioWKYmale2.32ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days)99953unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)
8renal plasma flow to body weight ratioWKYmale2.33ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days)99952unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 14 days)
8renal plasma flow to body weight ratioWKYmale3.09ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition99951unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) vehicle control condition
7renal plasma flow to body weight ratioWKYmale2.16ml/min/100gunilateral nephrectomy (for 28 days) then vehicle control condition99950unilateral nephrectomy (for 28 days)vehicle control condition
16renal plasma flow to body weight ratioWKYmale3.19ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days)99994unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 154 days)bosentan (100 mg/kg/d) (for 154 days)
16renal plasma flow to body weight ratioWKYmale3.15ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days)99993unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 154 days)
17renal plasma flow to body weight ratioWKYmale3.3ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days)99992unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 154 days)
17renal plasma flow to body weight ratioWKYmale1.72ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition99991unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) vehicle control condition
11renal plasma flow to body weight ratioWKYmale2.28ml/min/100gunilateral nephrectomy (for 28 days) then vehicle control condition99990unilateral nephrectomy (for 28 days)vehicle control condition
9renal plasma flowWKYmale5.45ml/mincontrolled enalapril content drinking water (50 mg/l) (for 497 days) then puromycin aminonucleoside (50 mg/kg) 100471controlled enalapril content drinking water (50 mg/l) (for 497 days)puromycin aminonucleoside (50 mg/kg)
8renal plasma flowWKYmale4.18ml/minpuromycin aminonucleoside (50 mg/kg) 100470puromycin aminonucleoside (50 mg/kg)
9renal plasma flowWKYmale4.99ml/min0.9% sodium chloride solution (3 ml) 1004690.9% sodium chloride solution (3 ml)
8renal plasma flowWKYmale4.15ml/mincontrolled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100468controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9renal plasma flowWKYmale3.79ml/minpuromycin aminonucleoside (50 mg/kg) 100467puromycin aminonucleoside (50 mg/kg)
8renal plasma flowWKYmale4.65ml/min0.9% sodium chloride solution (3 ml) 1004660.9% sodium chloride solution (3 ml)
5renal plasma flowWKYmale3.95ml/mincontrolled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) 100465controlled enalapril content drinking water (50 mg/l) (for 22 days)puromycin aminonucleoside (50 mg/kg)
7renal plasma flowWKYmale3.66ml/minpuromycin aminonucleoside (50 mg/kg) 100464puromycin aminonucleoside (50 mg/kg)
9renal plasma flowWKYmale4.5ml/min0.9% sodium chloride solution (3 ml) 1004630.9% sodium chloride solution (3 ml)
5renal plasma flowWKYmale4.37ml/minpuromycin aminonucleoside (50 mg/kg) then 0.9% sodium chloride solution (for 0.5 hours)100603puromycin aminonucleoside (50 mg/kg) 0.9% sodium chloride solution (for 0.5 hours)
5renal plasma flowWKYmale4.36ml/minpuromycin aminonucleoside (50 mg/kg) 100602puromycin aminonucleoside (50 mg/kg)
5renal plasma flowWKYmale4.6ml/minpuromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) 100601puromycin aminonucleoside (50 mg/kg) saralasin (0.3 mg/kg/hr)
5renal plasma flowWKYmale3.9ml/minpuromycin aminonucleoside (50 mg/kg) 100600puromycin aminonucleoside (50 mg/kg)
9renal filtration fractionWKYmale0.28controlled enalapril content drinking water (50 mg/l) (for 497 days) then puromycin aminonucleoside (50 mg/kg) 100480controlled enalapril content drinking water (50 mg/l) (for 497 days)puromycin aminonucleoside (50 mg/kg)
8renal filtration fractionWKYmale0.27puromycin aminonucleoside (50 mg/kg) 100479puromycin aminonucleoside (50 mg/kg)
9renal filtration fractionWKYmale0.320.9% sodium chloride solution (3 ml) 1004780.9% sodium chloride solution (3 ml)
8renal filtration fractionWKYmale0.28controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100477controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9renal filtration fractionWKYmale0.34puromycin aminonucleoside (50 mg/kg) 100476puromycin aminonucleoside (50 mg/kg)
8renal filtration fractionWKYmale0.260.9% sodium chloride solution (3 ml) 1004750.9% sodium chloride solution (3 ml)
5renal filtration fractionWKYmale0.09controlled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) 100474controlled enalapril content drinking water (50 mg/l) (for 22 days)puromycin aminonucleoside (50 mg/kg)
7renal filtration fractionWKYmale0.09puromycin aminonucleoside (50 mg/kg) 100473puromycin aminonucleoside (50 mg/kg)
9renal filtration fractionWKYmale0.260.9% sodium chloride solution (3 ml) 1004720.9% sodium chloride solution (3 ml)
9renal filtration fractionWKYmale0.28puromycin aminonucleoside (50 mg/kg) then 0.9% sodium chloride solution (for 0.5 hours)100607puromycin aminonucleoside (50 mg/kg) 0.9% sodium chloride solution (for 0.5 hours)
9renal filtration fractionWKYmale0.29puromycin aminonucleoside (50 mg/kg) 100606puromycin aminonucleoside (50 mg/kg)
9renal filtration fractionWKYmale0.32puromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours)100605puromycin aminonucleoside (50 mg/kg) saralasin (0.3 mg/kg/hr) (for 0.5 hours)
9renal filtration fractionWKYmale0.32puromycin aminonucleoside (50 mg/kg) 100604puromycin aminonucleoside (50 mg/kg)
8afferent colloid osmotic pressureWKYmale18mmHgcontrolled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100581controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9afferent colloid osmotic pressureWKYmale18mmHgpuromycin aminonucleoside (50 mg/kg) 100580puromycin aminonucleoside (50 mg/kg)
8afferent colloid osmotic pressureWKYmale18mmHg0.9% sodium chloride solution (3 ml) 1005790.9% sodium chloride solution (3 ml)
6afferent colloid osmotic pressureWKYmale12mmHgpuromycin aminonucleoside (50 mg/kg) 100578puromycin aminonucleoside (50 mg/kg)
9afferent colloid osmotic pressureWKYmale18.1mmHg0.9% sodium chloride solution (3 ml) 1005770.9% sodium chloride solution (3 ml)
8efferent colloid osmotic pressureWKYmale29mmHgcontrolled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100586controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9efferent colloid osmotic pressureWKYmale33mmHgpuromycin aminonucleoside (50 mg/kg) 100585puromycin aminonucleoside (50 mg/kg)
8efferent colloid osmotic pressureWKYmale31mmHg0.9% sodium chloride solution (3 ml) 1005840.9% sodium chloride solution (3 ml)
6efferent colloid osmotic pressureWKYmale14mmHgpuromycin aminonucleoside (50 mg/kg) 100583puromycin aminonucleoside (50 mg/kg)
9efferent colloid osmotic pressureWKYmale29mmHg0.9% sodium chloride solution (3 ml) 1005820.9% sodium chloride solution (3 ml)
8mean proximal tubular hydraulic pressureWKYmale16mmHgcontrolled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100541controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9mean proximal tubular hydraulic pressureWKYmale19mmHgpuromycin aminonucleoside (50 mg/kg) 100540puromycin aminonucleoside (50 mg/kg)
8mean proximal tubular hydraulic pressureWKYmale14mmHg0.9% sodium chloride solution (3 ml) 1005390.9% sodium chloride solution (3 ml)
6mean proximal tubular hydraulic pressureWKYmale15mmHgpuromycin aminonucleoside (50 mg/kg) 100538puromycin aminonucleoside (50 mg/kg)
9mean proximal tubular hydraulic pressureWKYmale14mmHg0.9% sodium chloride solution (3 ml) 1005370.9% sodium chloride solution (3 ml)
8glomerular transcapillary hydraulic pressure gradientWKYmale31mmHgcontrolled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100551controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9glomerular transcapillary hydraulic pressure gradientWKYmale48mmHgpuromycin aminonucleoside (50 mg/kg) 100550puromycin aminonucleoside (50 mg/kg)
8glomerular transcapillary hydraulic pressure gradientWKYmale33mmHg0.9% sodium chloride solution (3 ml) 1005490.9% sodium chloride solution (3 ml)
6glomerular transcapillary hydraulic pressure gradientWKYmale35mmHgpuromycin aminonucleoside (50 mg/kg) 100548puromycin aminonucleoside (50 mg/kg)
9glomerular transcapillary hydraulic pressure gradientWKYmale35mmHg0.9% sodium chloride solution (3 ml) 1005470.9% sodium chloride solution (3 ml)
8efferent arteriolar hydraulic pressureWKYmale24mmHgenalapril (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 109969enalapril (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
8efferent arteriolar hydraulic pressureWKYmale17mmHg0.9% sodium chloride solution (3 ml) 1099670.9% sodium chloride solution (3 ml)
6efferent arteriolar hydraulic pressureWKYmale21mmHgpuromycin aminonucleoside (50 mg/kg) 109966puromycin aminonucleoside (50 mg/kg)
9efferent arteriolar hydraulic pressureWKYmale18mmHg0.9% sodium chloride solution (3 ml) 1099650.9% sodium chloride solution (3 ml)
9efferent arteriolar hydraulic pressureWKYmale22mmHgpuromycin aminonucleoside (50 mg/kg) 109968puromycin aminonucleoside (50 mg/kg)
8single nephron filtration fractionWKYmale0.26controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100526controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9single nephron filtration fractionWKYmale0.31puromycin aminonucleoside (50 mg/kg) 100525puromycin aminonucleoside (50 mg/kg)
8single nephron filtration fractionWKYmale0.280.9% sodium chloride solution (3 ml) 1005240.9% sodium chloride solution (3 ml)
6single nephron filtration fractionWKYmale0.09puromycin aminonucleoside (50 mg/kg) 100523puromycin aminonucleoside (50 mg/kg)
9single nephron filtration fractionWKYmale0.260.9% sodium chloride solution (3 ml) 1005220.9% sodium chloride solution (3 ml)