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PhenoMiner Database Result        View data table  |  Download data table  |  View expanded data table        


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Rat Strains

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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1Condition 2Condition 3aCondition 3b
7glomerular filtration rate to body weight ratioWKYmale0.494ml/min/100gunilateral nephrectomy (for 28 days) then vehicle control condition99945unilateral nephrectomy (for 28 days)vehicle control condition
8glomerular filtration rate to body weight ratioWKYmale0.792ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition99946unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) vehicle control condition
8glomerular filtration rate to body weight ratioWKYmale0.516ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days)99947unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 14 days)
8glomerular filtration rate to body weight ratioWKYmale0.536ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days)99948unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)
6glomerular filtration rate to body weight ratioWKYmale0.504ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days)99949unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)bosentan (100 mg/kg/d) (for 14 days)
7renal filtration fractionWKYmale0.233unilateral nephrectomy (for 28 days) then vehicle control condition99955unilateral nephrectomy (for 28 days)vehicle control condition
8renal filtration fractionWKYmale0.26unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition99956unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) vehicle control condition
8renal filtration fractionWKYmale0.233unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days)99957unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 14 days)
8renal filtration fractionWKYmale0.234unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days)99958unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)
6renal filtration fractionWKYmale0.21unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days)99959unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 14 days)bosentan (100 mg/kg/d) (for 14 days)
9glomerular capillary ultrafiltration coefficientWKYmale0.073nl/(s x mmHg)0.9% sodium chloride solution (3 ml) 1005870.9% sodium chloride solution (3 ml)
6glomerular capillary ultrafiltration coefficientWKYmale0.015nl/(s x mmHg)puromycin aminonucleoside (50 mg/kg) 100588puromycin aminonucleoside (50 mg/kg)
8glomerular capillary ultrafiltration coefficientWKYmale0.092nl/(s x mmHg)0.9% sodium chloride solution (3 ml) 1005890.9% sodium chloride solution (3 ml)
9glomerular capillary ultrafiltration coefficientWKYmale0.039nl/(s x mmHg)puromycin aminonucleoside (50 mg/kg) 100590puromycin aminonucleoside (50 mg/kg)
8glomerular capillary ultrafiltration coefficientWKYmale0.108nl/(s x mmHg)controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100591controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
11glomerular filtration rate to body weight ratioWKYmale0.517ml/min/100gunilateral nephrectomy (for 28 days) then vehicle control condition99980unilateral nephrectomy (for 28 days)vehicle control condition
17glomerular filtration rate to body weight ratioWKYmale0.496ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition99981unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) vehicle control condition
17glomerular filtration rate to body weight ratioWKYmale0.69ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days)99982unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 154 days)
16glomerular filtration rate to body weight ratioWKYmale0.664ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days)99983unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 154 days)
16glomerular filtration rate to body weight ratioWKYmale0.673ml/min/100gunilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days)99984unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 154 days)bosentan (100 mg/kg/d) (for 154 days)
11renal filtration fractionWKYmale0.23unilateral nephrectomy (for 28 days) then vehicle control condition99985unilateral nephrectomy (for 28 days)vehicle control condition
17renal filtration fractionWKYmale0.293unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition99986unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) vehicle control condition
17renal filtration fractionWKYmale0.214unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days)99987unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) bosentan (100 mg/kg/d) (for 154 days)
16renal filtration fractionWKYmale0.216unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days)99988unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 154 days)
16renal filtration fractionWKYmale0.213unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days)99989unilateral nephrectomy (for 28 days)streptozotocin (35 mg/kg) enalapril (10 mg/kg/d) (for 154 days)bosentan (100 mg/kg/d) (for 154 days)
5blood glomerular filtration rateWKYmale1.22ml/minpuromycin aminonucleoside (50 mg/kg) 100596puromycin aminonucleoside (50 mg/kg)
5blood glomerular filtration rateWKYmale1.49ml/minpuromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours)100597puromycin aminonucleoside (50 mg/kg) saralasin (0.3 mg/kg/hr) (for 0.5 hours)
5blood glomerular filtration rateWKYmale1.24ml/minpuromycin aminonucleoside (50 mg/kg) 100598puromycin aminonucleoside (50 mg/kg)
5blood glomerular filtration rateWKYmale1.19ml/minpuromycin aminonucleoside (50 mg/kg) then 0.9% sodium chloride solution (for 0.5 hours)100599puromycin aminonucleoside (50 mg/kg) 0.9% sodium chloride solution (for 0.5 hours)
5single nephron glomerular filtration rateWKYmale82nl/minpuromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours)100609puromycin aminonucleoside (50 mg/kg) saralasin (0.3 mg/kg/hr) (for 0.5 hours)
5single nephron glomerular filtration rateWKYmale65nl/minpuromycin aminonucleoside (50 mg/kg) 100610puromycin aminonucleoside (50 mg/kg)
5glomerular capillary ultrafiltration coefficientWKYmale0.162nl/(s x mmHg)puromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours)100617puromycin aminonucleoside (50 mg/kg) saralasin (0.3 mg/kg/hr) (for 0.5 hours)
5single nephron glomerular filtration rateWKYmale67nl/minpuromycin aminonucleoside (50 mg/kg) 100608puromycin aminonucleoside (50 mg/kg)
5single nephron glomerular filtration rateWKYmale57nl/minpuromycin aminonucleoside (50 mg/kg) then 0.9% sodium chloride solution (for 0.5 hours)100611puromycin aminonucleoside (50 mg/kg) 0.9% sodium chloride solution (for 0.5 hours)
5afferent arteriolar plasma flow rateWKYmale270nl/minpuromycin aminonucleoside (50 mg/kg) 100612puromycin aminonucleoside (50 mg/kg)
5afferent arteriolar plasma flow rateWKYmale314nl/minpuromycin aminonucleoside (50 mg/kg) (for 0.5 hours) then saralasin (0.3 mg/kg/hr) 100613puromycin aminonucleoside (50 mg/kg) (for 0.5 hours)saralasin (0.3 mg/kg/hr)
5glomerular capillary ultrafiltration coefficientWKYmale0.055nl/(s x mmHg)puromycin aminonucleoside (50 mg/kg) 100616puromycin aminonucleoside (50 mg/kg)
9single nephron glomerular filtration rateWKYmale44.4nl/min0.9% sodium chloride solution (3 ml) 1005170.9% sodium chloride solution (3 ml)
6single nephron glomerular filtration rateWKYmale17nl/minpuromycin aminonucleoside (50 mg/kg) 100518puromycin aminonucleoside (50 mg/kg)
8single nephron glomerular filtration rateWKYmale52nl/min0.9% sodium chloride solution (3 ml) 1005190.9% sodium chloride solution (3 ml)
9single nephron glomerular filtration rateWKYmale50nl/minpuromycin aminonucleoside (50 mg/kg) 100520puromycin aminonucleoside (50 mg/kg)
8single nephron glomerular filtration rateWKYmale61nl/mincontrolled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100521controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9afferent arteriolar plasma flow rateWKYmale165nl/min0.9% sodium chloride solution (3 ml) 1005270.9% sodium chloride solution (3 ml)
6afferent arteriolar plasma flow rateWKYmale186nl/minpuromycin aminonucleoside (50 mg/kg) 100528puromycin aminonucleoside (50 mg/kg)
8afferent arteriolar plasma flow rateWKYmale191nl/min0.9% sodium chloride solution (3 ml) 1005290.9% sodium chloride solution (3 ml)
9afferent arteriolar plasma flow rateWKYmale169nl/minpuromycin aminonucleoside (50 mg/kg) 100530puromycin aminonucleoside (50 mg/kg)
8afferent arteriolar plasma flow rateWKYmale244nl/mincontrolled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100531controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9glomerular capillary hydraulic pressureWKYmale49mmHg0.9% sodium chloride solution (3 ml) 1005320.9% sodium chloride solution (3 ml)
6glomerular capillary hydraulic pressureWKYmale50mmHgpuromycin aminonucleoside (50 mg/kg) 100533puromycin aminonucleoside (50 mg/kg)
8glomerular capillary hydraulic pressureWKYmale47mmHg0.9% sodium chloride solution (3 ml) 1005340.9% sodium chloride solution (3 ml)
9glomerular capillary hydraulic pressureWKYmale68mmHgpuromycin aminonucleoside (50 mg/kg) 100535puromycin aminonucleoside (50 mg/kg)
8glomerular capillary hydraulic pressureWKYmale46mmHgcontrolled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100536controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9blood glomerular filtration rateWKYmale1.17ml/min0.9% sodium chloride solution (3 ml) 1004540.9% sodium chloride solution (3 ml)
7blood glomerular filtration rateWKYmale0.31ml/minpuromycin aminonucleoside (50 mg/kg) 100455puromycin aminonucleoside (50 mg/kg)
5blood glomerular filtration rateWKYmale0.38ml/mincontrolled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) 100456controlled enalapril content drinking water (50 mg/l) (for 22 days)puromycin aminonucleoside (50 mg/kg)
8blood glomerular filtration rateWKYmale1.34ml/min0.9% sodium chloride solution (3 ml) 1004570.9% sodium chloride solution (3 ml)
9blood glomerular filtration rateWKYmale1.28ml/minpuromycin aminonucleoside (50 mg/kg) 100458puromycin aminonucleoside (50 mg/kg)
8blood glomerular filtration rateWKYmale1.25ml/mincontrolled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) 100459controlled enalapril content drinking water (50 mg/l) (for 7 days)puromycin aminonucleoside (50 mg/kg)
9blood glomerular filtration rateWKYmale1.51ml/min0.9% sodium chloride solution (3 ml) 1004600.9% sodium chloride solution (3 ml)
8blood glomerular filtration rateWKYmale1.14ml/minpuromycin aminonucleoside (50 mg/kg) 100461puromycin aminonucleoside (50 mg/kg)
9blood glomerular filtration rateWKYmale1.43ml/mincontrolled enalapril content drinking water (50 mg/l) (for 497 days) then puromycin aminonucleoside (50 mg/kg) 100462controlled enalapril content drinking water (50 mg/l) (for 497 days)puromycin aminonucleoside (50 mg/kg)