Phenominer Database Results (136 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Clinical Measurement Notes Record ID Study ID
MWF/ZtmRrrc single nephron glomerular filtration rate control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 8 46.9 nl/min 1.41 4.0 inulin analysis by liquid phase colorimetry 0.0 0 100969 2541
WKY glomerular capillary ultrafiltration coefficient 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 8 0.09 nl/(s x mmHg) 0.01 0.03 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 0 kf 100589 2479
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 17 0.5 ml/min/100g 0.03 0.12 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99981 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 16 0.66 ml/min/100g 0.02 0.09 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99983 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 11 0.23 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99985 2378
MW glomerular filtration rate right nephrectomy (for 112 days) then reserpine (5 mg/l) (for 56 days) and hydralazine (80 mg/l) (for 56 days) and controlled hydralazine content drinking water (25 mg/l) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. glomerular filtration trait male 0 days 10 0.32 ml/min 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 ~5/6 to 7/8 nephrectomy 112 days 100884 2523
SS/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.54 ml/min/g 0.13 inulin analysis by liquid phase colorimetry 0.0 0 102217 2681
MW glomerular filtration rate nephrectomy (for 28 days) then enalapril (50 mg/l) (for 21 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. glomerular filtration trait male 0 days 8 0.54 ml/min 0.05 0.14 inulin analysis by liquid phase colorimetry 0.0 5/6 nephrectomy 28 days 100993 2561
WKY glomerular filtration rate controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 8 1.25 ml/min 0.09 0.25 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 100459 2479
WKY glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 9 1.51 ml/min 0.12 0.36 inulin analysis by liquid phase colorimetry 0.0 0 100460 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 6 17.0 nl/min 2.0 4.9 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days sngfr 100518 2479
WKY afferent arteriolar plasma flow rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male 0 days 8 191.0 nl/min 16.0 45.25 inulin analysis by liquid phase colorimetry 0.0 0 afferent arteriolar plasma flow rate 100529 2479
WKY glomerular capillary hydraulic pressure puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male 0 days 6 50.0 mmHg 3.0 7.35 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days pgc 100533 2479
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 7 0.49 ml/min/100g 0.03 0.08 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99945 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.23 null 0.12 0.34 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99957 2378
MNS glomerular filtration rate control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. glomerular filtration trait male 126 days 6 3.35 ml/min 0.18 0.43 inulin analysis by liquid phase colorimetry 0.0 0 104114 2907
MHS renal vascular resistance streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. renal blood flow trait male 126 days 6 6.2 mmHg/ml/min 0.35 0.86 inulin analysis by liquid phase colorimetry 0.0 0 104129 2907
MNS glomerular filtration rate to kidney weight ratio control condition Capasso G, et al., Am J Physiol Renal Physiol. 2005 Jun;288(6):F1173-82. doi: 10.1152/ajprenal.00228.2004. Epub 2005 Feb 1. glomerular filtration trait not specified 23 days-25 days 11 1.2 ml/min/g 0.07 0.23 inulin analysis by liquid phase colorimetry 0.0 0 104158 2926
MWF/Ztm renal plasma flow (inulin) arterial catheter implantation and controlled hemorrhage Remuzzi A, etal., Kidney Int. 1988 Oct;34(4):481-6. doi: 10.1038/ki.1988.206. kidney plasma flow trait male 126 days-147 days 8 0.57 ml/min 0.05 0.15 inulin analysis by liquid phase colorimetry 0.0 0 109238 3138
MNS renal vascular resistance streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. renal blood flow trait male 126 days 6 5.04 mmHg/ml/min 0.24 0.59 inulin analysis by liquid phase colorimetry 0.0 0 104127 2907
MWF/ZtmRrrc glomerular filtration rate to body weight ratio enalapril (50 mg/l) (for 60 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 8 0.58 ml/min/100g 0.02 0.05 inulin analysis by liquid phase colorimetry 0.0 0 100932 2541
MWF/ZtmRrrc single nephron glomerular filtration rate enalapril (50 mg/l) (for 60 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 10 54.6 nl/min 2.25 7.1 inulin analysis by liquid phase colorimetry 0.0 0 100970 2541
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 17 0.29 null 0.01 0.05 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99986 2378
MW glomerular filtration rate unilateral nephrectomy (for 70 days) then vehicle control condition Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. glomerular filtration trait male 0 days 7 1.46 ml/min 0.08 0.21 inulin analysis by liquid phase colorimetry 0.0 unx 70 days 101205 2581
SD glomerular filtration rate control condition Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. glomerular filtration trait male 420 days-450 days 9 1.63 ml/min 0.12 0.36 inulin analysis by liquid phase colorimetry 0.0 0 101225 2582
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.26 null 0.01 0.04 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99956 2378
MWF/ZtmRrrc glomerular filtration rate to body weight ratio control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 7 0.44 ml/min/100g 0.02 0.06 inulin analysis by liquid phase colorimetry 0.0 0 100931 2541
MWF/ZtmRrrc glomerular capillary ultrafiltration coefficient enalapril (50 mg/l) (for 60 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 10 0.13 nl/(s x mmHg) 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 0 100982 2541
MHS glomerular filtration rate streptozotocin (50 mg/kg) (for 147 days) and insulin (2 IU/d) (for 147 days) Ge Y, et al., Physiol Rep. 2017 Feb;5(3). pii: 5/3/e13089. doi: 10.14814/phy2.13089. glomerular filtration trait male 213 days 6 0.0 ml/min 0.0 0.0 inulin analysis by liquid phase colorimetry 0.0 0 104027 2886
WKY glomerular capillary ultrafiltration coefficient puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 0.06 nl/(s x mmHg) 0.02 0.04 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg 0 kf 100616 2479
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 17 0.21 null 0.01 0.05 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99987 2378
SR/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.49 ml/min/g 0.2 inulin analysis by liquid phase colorimetry 0.0 0 102214 2681
MW glomerular filtration rate unilateral nephrectomy (for 70 days) then puromycin aminonucleoside (100 mg/kg) then puromycin aminonucleoside (40 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. glomerular filtration trait male 0 days 6 0.57 ml/min 0.07 0.17 inulin analysis by liquid phase colorimetry 0.0 unx 70 days 101204 2581
MW glomerular filtration rate control condition Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. glomerular filtration trait male 0 days 18 0.99 ml/min 0.08 0.34 inulin analysis by liquid phase colorimetry 0.0 control 29 days 101208 2581
MWF/ZtmRrrc glomerular filtration rate enalapril (50 mg/l) (for 60 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 10 0.96 ml/min 0.04 0.14 inulin analysis by liquid phase colorimetry 0.0 0 100926 2541
MWF/ZtmRrrc glomerular filtration rate control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 246 days 8 1.94 ml/min 0.17 0.47 inulin analysis by liquid phase colorimetry 0.0 0 100929 2541
WKY glomerular capillary hydraulic pressure puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male 0 days 9 68.0 mmHg 2.0 6.0 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 pgc 100535 2479
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.23 null 0.14 0.4 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99958 2378
MHS glomerular filtration rate streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. glomerular filtration trait male 126 days 6 3.43 ml/min 0.13 0.31 inulin analysis by liquid phase colorimetry 0.0 0 104117 2907
MHS renal plasma flow (inulin) streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. kidney plasma flow trait male 126 days 6 13.66 ml/min 0.62 1.51 inulin analysis by liquid phase colorimetry 0.0 0 104125 2907
MNS renal vascular resistance control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. renal blood flow trait male 126 days 6 4.79 mmHg/ml/min 0.29 0.7 inulin analysis by liquid phase colorimetry 0.0 0 104126 2907
MNS glomerular filtration rate to body weight ratio control condition Capasso G, etal., Am J Physiol Renal Physiol. 2008 Aug;295(2):F556-67. doi: 10.1152/ajprenal.00340.2007. Epub 2008 May 14. glomerular filtration trait not specified 85 days-87 days 11 0.84 ml/min/100g 0.04 0.13 inulin analysis by liquid phase colorimetry 0.0 0 110142 3164
MHS glomerular filtration rate to body weight ratio control condition Capasso G, etal., Am J Physiol Renal Physiol. 2008 Aug;295(2):F556-67. doi: 10.1152/ajprenal.00340.2007. Epub 2008 May 14. glomerular filtration trait not specified 85 days-87 days 11 0.81 ml/min/100g 0.04 0.13 inulin analysis by liquid phase colorimetry 0.0 0 110143 3164
MWF glomerular filtration rate cyclosporine A (50 ml/kg/d) (for 7 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. glomerular filtration trait male 133 days-147 days 6 0.49 ml/min 0.1 0.24 inulin analysis by liquid phase colorimetry 0.0 0 110080 3163
MWF glomerular filtration rate cyclosporine A (50 ml/kg/d) (for 7 days) and lacidipine (1 mg/kg/d) (for 7 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. glomerular filtration trait male 133 days-147 days 7 0.77 ml/min 0.06 0.16 inulin analysis by liquid phase colorimetry 0.0 0 110081 3163
MHS glomerular filtration rate control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. glomerular filtration trait male 126 days 6 3.06 ml/min 0.31 0.77 inulin analysis by liquid phase colorimetry 0.0 0 104116 2907
MHS renal filtration fraction streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. glomerular filtration trait male 126 days 6 ((A-V)/A)*100 0.25 null 0.0 0.01 inulin analysis by liquid phase colorimetry 0.0 0 filtration fraction 104121 2907
MW glomerular filtration rate nephrectomy (for 28 days) then control condition Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. glomerular filtration trait male 0 days 8 0.6 ml/min 0.07 0.2 inulin analysis by liquid phase colorimetry 0.0 5/6 nephrectomy 28 days 100992 2561
MW glomerular filtration rate nephrectomy (for 28 days) then reserpine (5 mg/l) (for 21 days) and hydralazine (80 mg/l) (for 21 days) and controlled hydralazine content drinking water (25 mg/l) (for 21 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. glomerular filtration trait male 0 days 8 0.61 ml/min 0.08 0.23 inulin analysis by liquid phase colorimetry 0.0 5/6 nephrectomy 28 days 100994 2561
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) then 0.9% sodium chloride solution (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 1.19 ml/min 0.08 0.18 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 100599 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) then 0.9% sodium chloride solution (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 57.0 nl/min 8.0 17.89 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 sngfr 100611 2479
MNS glomerular filtration rate streptozotocin (50 mg/kg) (for 147 days) and insulin (2 IU/d) (for 147 days) Ge Y, et al., Physiol Rep. 2017 Feb;5(3). pii: 5/3/e13089. doi: 10.14814/phy2.13089. glomerular filtration trait male 213 days 9 0.0 ml/min 0.0 0.0 inulin analysis by liquid phase colorimetry 0.0 0 104028 2886
WKY glomerular capillary ultrafiltration coefficient 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 9 0.07 nl/(s x mmHg) 0.01 0.04 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 0 kf 100587 2479
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 11 0.52 ml/min/100g 0.01 0.04 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99980 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 16 0.22 null 0.01 0.04 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99988 2378
MW glomerular filtration rate right nephrectomy (for 112 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. glomerular filtration trait male 0 days 6 0.05 ml/min 0.01 0.02 inulin analysis by liquid phase colorimetry 0.0 ~5/6 to 7/8 nephrectomy 112 days 100883 2523
MW glomerular filtration rate right nephrectomy (for 112 days) then angiotensin II receptor antagonist (20 mg/l) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. glomerular filtration trait male 0 days 7 0.36 ml/min 0.06 0.16 inulin analysis by liquid phase colorimetry 0.0 ~5/6 to 7/8 nephrectomy 112 days 100888 2523
WKY single nephron glomerular filtration rate controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 8 61.0 nl/min 3.0 8.49 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 100521 2479
MWF/ZtmRrrc glomerular filtration rate to body weight ratio control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 246 days 8 0.44 ml/min/100g 0.04 0.11 inulin analysis by liquid phase colorimetry 0.0 0 100933 2541
MWF/ZtmRrrc single nephron filtration fraction control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 8 0.29 null 0.01 0.02 inulin analysis by liquid phase colorimetry 0.0 0 100971 2541
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 65.0 nl/min 9.0 20.12 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 sngfr 100610 2479
SR/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 1.97 ml/min/g 0.25 inulin analysis by liquid phase colorimetry 0.0 0 102215 2681
SS/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 1.96 ml/min/g 0.04 inulin analysis by liquid phase colorimetry 0.0 0 102218 2681
SD glomerular filtration rate to body weight ratio control condition Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. glomerular filtration trait male 90 days 9 0.3 ml/min/100g 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 0 101226 2582
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.52 ml/min/100g 0.03 0.07 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99947 2378
WKY single nephron glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 9 44.4 nl/min 4.0 12.0 inulin analysis by liquid phase colorimetry 0.0 0 sngfr 100517 2479
WKY afferent arteriolar plasma flow rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male 0 days 9 165.0 nl/min 17.0 51.0 inulin analysis by liquid phase colorimetry 0.0 0 afferent arteriolar plasma flow rate 100527 2479
WKY afferent arteriolar plasma flow rate controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male 0 days 8 244.0 nl/min 21.0 59.4 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 afferent arteriolar plasma flow rate 100531 2479
MWF/ZtmRrrc glomerular filtration rate control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 8 0.81 ml/min 0.04 0.1 inulin analysis by liquid phase colorimetry 0.0 0 100925 2541
MWF/ZtmRrrc glomerular filtration rate enalapril (50 mg/l) (for 60 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 8 2.17 ml/min 0.1 0.28 inulin analysis by liquid phase colorimetry 0.0 0 100928 2541
WKY glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 9 1.17 ml/min 0.05 0.15 inulin analysis by liquid phase colorimetry 0.0 0 100454 2479
WKY glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 8 1.34 ml/min 0.06 0.17 inulin analysis by liquid phase colorimetry 0.0 0 100457 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 9 1.28 ml/min 0.06 0.18 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 100458 2479
MNS renal filtration fraction streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. glomerular filtration trait male 126 days 6 ((A-V)/A)*100 0.31 null 0.0 0.01 inulin analysis by liquid phase colorimetry 0.0 0 filtration fraction 104119 2907
MWF single nephron glomerular filtration rate castor oil Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. glomerular filtration trait male 133 days-147 days 7 68.9 nl/min 9.0 23.8 inulin analysis by liquid phase colorimetry 0.0 0 110118 3163
MWF single nephron glomerular filtration rate cyclosporine A (50 ml/kg/d) (for 7 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. glomerular filtration trait male 133 days-147 days 6 34.0 nl/min 4.78 11.7 inulin analysis by liquid phase colorimetry 0.0 0 110119 3163
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.79 ml/min/100g 0.03 0.08 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99946 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 8 0.54 ml/min/100g 0.02 0.05 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99948 2378
MWF/ZtmRrrc glomerular filtration rate to body weight ratio enalapril (50 mg/l) (for 182 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 246 days 6 0.54 ml/min/100g 0.03 0.07 inulin analysis by liquid phase colorimetry 0.0 0 100934 2541
MWF/ZtmRrrc single nephron filtration fraction enalapril (50 mg/l) (for 60 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 10 0.31 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 0 100972 2541
MWF/ZtmRrrc afferent arteriolar plasma flow rate enalapril (50 mg/l) (for 60 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. kidney plasma flow trait male 126 days 10 178.0 nl/min 9.17 29.0 inulin analysis by liquid phase colorimetry 0.0 0 100974 2541
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 1.24 ml/min 0.07 0.16 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 100598 2479
WKY glomerular capillary ultrafiltration coefficient puromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 0.16 nl/(s x mmHg) 0.05 0.1 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg 0 kf 100617 2479
WKY afferent arteriolar plasma flow rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male 0 days 5 270.0 nl/min 44.0 98.39 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 qa 100612 2479
WKY glomerular capillary ultrafiltration coefficient controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 8 0.11 nl/(s x mmHg) 0.03 0.07 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg 0 kf 100591 2479
SR/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.2 ml/min/g 0.31 inulin analysis by liquid phase colorimetry 0.0 0 102213 2681
MW glomerular filtration rate right nephrectomy (for 112 days) then captopril (30 mg/kg/d) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. glomerular filtration trait male 0 days 10 0.67 ml/min 0.1 0.32 inulin analysis by liquid phase colorimetry 0.0 ~5/6 to 7/8 nephrectomy 112 days 100885 2523
MW glomerular filtration rate right nephrectomy (for 112 days) then lisinopril (10 mg/kg/d) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. glomerular filtration trait male 0 days 10 0.36 ml/min 0.05 0.16 inulin analysis by liquid phase colorimetry 0.0 ~5/6 to 7/8 nephrectomy 112 days 100887 2523
MW glomerular filtration rate unilateral nephrectomy (for 70 days) and captopril (500 mg/l) (for 70 days) then puromycin aminonucleoside (100 mg/kg) then puromycin aminonucleoside (40 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. glomerular filtration trait male 0 days 5 0.94 ml/min 0.11 0.25 inulin analysis by liquid phase colorimetry 0.0 unx 70 days 101206 2581
SD glomerular filtration rate to body weight ratio control condition Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. glomerular filtration trait male 420 days-450 days 9 0.28 ml/min/100g 0.02 0.06 inulin analysis by liquid phase colorimetry 0.0 0 101227 2582
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 16 0.21 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99989 2378
MWF/ZtmRrrc glomerular filtration rate control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 7 1.7 ml/min 0.08 0.22 inulin analysis by liquid phase colorimetry 0.0 0 100927 2541
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 7 0.31 ml/min 0.05 0.13 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days 100455 2479
WKY glomerular filtration rate controlled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 0.38 ml/min 0.08 0.18 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days 100456 2479
WKY single nephron glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 8 52.0 nl/min 3.0 8.49 inulin analysis by liquid phase colorimetry 0.0 0 sngfr 100519 2479
WKY glomerular capillary hydraulic pressure 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male 0 days 9 49.0 mmHg 1.0 3.0 inulin analysis by liquid phase colorimetry 0.0 0 pgc 100532 2479
WKY glomerular capillary hydraulic pressure controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male 0 days 8 46.0 mmHg 2.0 5.66 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 pgc 100536 2479
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 7 0.23 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99955 2378
MHS glomerular filtration rate to kidney weight ratio control condition Capasso G, et al., Am J Physiol Renal Physiol. 2005 Jun;288(6):F1173-82. doi: 10.1152/ajprenal.00228.2004. Epub 2005 Feb 1. glomerular filtration trait not specified 23 days-25 days 11 1.88 ml/min/g 0.14 0.46 inulin analysis by liquid phase colorimetry 0.0 0 104159 2926
MNS renal filtration fraction control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. glomerular filtration trait male 126 days 6 ((A-V)/A)*100 0.25 null 0.02 0.05 inulin analysis by liquid phase colorimetry 0.0 0 filtration fraction 104118 2907
MHS renal filtration fraction control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. glomerular filtration trait male 126 days 6 ((A-V)/A)*100 0.24 null 0.02 0.04 inulin analysis by liquid phase colorimetry 0.0 0 filtration fraction 104120 2907
MNS renal plasma flow (inulin) control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. kidney plasma flow trait male 126 days 6 13.88 ml/min 0.85 2.07 inulin analysis by liquid phase colorimetry 0.0 0 104122 2907
MNS renal plasma flow (inulin) streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. kidney plasma flow trait male 126 days 6 13.39 ml/min 0.53 1.3 inulin analysis by liquid phase colorimetry 0.0 0 104123 2907
MHS renal vascular resistance control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. renal blood flow trait male 126 days 6 6.59 mmHg/ml/min 0.7 1.72 inulin analysis by liquid phase colorimetry 0.0 0 104128 2907
MWF glomerular filtration rate castor oil Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. glomerular filtration trait male 133 days-147 days 7 0.88 ml/min 0.1 0.26 inulin analysis by liquid phase colorimetry 0.0 0 110079 3163
MWF/ZtmRrrc afferent arteriolar plasma flow rate control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. kidney plasma flow trait male 126 days 8 161.0 nl/min 7.07 20.0 inulin analysis by liquid phase colorimetry 0.0 0 100973 2541
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 17 0.69 ml/min/100g 0.03 0.13 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99982 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 16 0.67 ml/min/100g 0.02 0.08 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99984 2378
MW glomerular filtration rate right nephrectomy (for 112 days) then enalapril (20 mg/kg/d) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. glomerular filtration trait male 0 days 9 0.38 ml/min 0.1 0.3 inulin analysis by liquid phase colorimetry 0.0 ~5/6 to 7/8 nephrectomy 112 days 100886 2523
MWF/ZtmRrrc glomerular capillary ultrafiltration coefficient control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 126 days 8 0.06 nl/(s x mmHg) 0.01 0.02 inulin analysis by liquid phase colorimetry 0.0 0 100981 2541
WKY glomerular capillary ultrafiltration coefficient puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 6 0.02 nl/(s x mmHg) 0.0 0.01 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg 15 days kf 100588 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 1.22 ml/min 0.03 0.07 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 100596 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 1.49 ml/min 0.09 0.2 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 100597 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 67.0 nl/min 13.0 29.07 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 sngfr 100608 2479
WKY afferent arteriolar plasma flow rate puromycin aminonucleoside (50 mg/kg) (for 0.5 hours) then saralasin (0.3 mg/kg/hr) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male 0 days 5 314.0 nl/min 34.0 76.03 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 qa 100613 2479
WKY glomerular capillary ultrafiltration coefficient puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 9 0.04 nl/(s x mmHg) 0.0 0.01 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg 0 kf 100590 2479
SS/JrHsd glomerular filtration rate to kidney weight ratio controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. glomerular filtration trait female 0 days 0 2.46 ml/min/g 0.06 inulin analysis by liquid phase colorimetry 0.0 0 102216 2681
SD glomerular filtration rate control condition Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. glomerular filtration trait male 90 days 9 1.2 ml/min 0.06 0.18 inulin analysis by liquid phase colorimetry 0.0 0 101224 2582
MW glomerular filtration rate right nephrectomy (for 112 days) then angiotensin II receptor antagonist (80 mg/l) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. glomerular filtration trait male 0 days 5 0.42 ml/min 0.06 0.13 inulin analysis by liquid phase colorimetry 0.0 ~5/6 to 7/8 nephrectomy 112 days 100889 2523
MWF/ZtmRrrc glomerular filtration rate enalapril (50 mg/l) (for 182 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. glomerular filtration trait male 246 days 6 2.37 ml/min 0.11 0.26 inulin analysis by liquid phase colorimetry 0.0 0 100930 2541
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 8 1.14 ml/min 0.13 0.37 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 490 days 100461 2479
WKY glomerular filtration rate controlled enalapril content drinking water (50 mg/l) (for 497 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 9 1.43 ml/min 0.09 0.27 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 490 days 100462 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 9 50.0 nl/min 3.0 9.0 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 sngfr 100520 2479
WKY afferent arteriolar plasma flow rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male 0 days 6 186.0 nl/min 17.0 41.64 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days afferent arteriolar plasma flow rate 100528 2479
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 6 0.5 ml/min/100g 0.02 0.06 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99949 2378
MNS glomerular filtration rate streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 42 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. glomerular filtration trait male 126 days 6 4.1 ml/min 0.13 0.33 inulin analysis by liquid phase colorimetry 0.0 0 104115 2907
MHS renal plasma flow (inulin) control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. kidney plasma flow trait male 126 days 6 12.66 ml/min 0.95 2.32 inulin analysis by liquid phase colorimetry 0.0 0 104124 2907
MWF/Ztm ratio of renal plasma flow to kidney weight (inulin) arterial catheter implantation and controlled hemorrhage Remuzzi A, etal., Kidney Int. 1988 Oct;34(4):481-6. doi: 10.1038/ki.1988.206. kidney plasma flow trait male 126 days-147 days 8 0.66 ml/min/g 0.05 0.13 inulin analysis by liquid phase colorimetry 0.0 0 109243 3138
MWF single nephron glomerular filtration rate cyclosporine A (50 ml/kg/d) (for 7 days) and lacidipine (1 mg/kg/d) (for 7 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. glomerular filtration trait male 133 days-147 days 7 43.1 nl/min 5.4 14.3 inulin analysis by liquid phase colorimetry 0.0 0 110120 3163
MWF/Ztm renal plasma flow (inulin) arterial catheter implantation and controlled hemorrhage Remuzzi A, etal., Kidney Int. 1988 Oct;34(4):481-6. doi: 10.1038/ki.1988.206. kidney plasma flow trait male 112 days-147 days 8 1.21 ml/min 0.13 0.36 inulin analysis by liquid phase colorimetry 0.0 0 109237 3138
MWF/Ztm ratio of renal plasma flow to kidney weight (inulin) arterial catheter implantation and controlled hemorrhage Remuzzi A, etal., Kidney Int. 1988 Oct;34(4):481-6. doi: 10.1038/ki.1988.206. kidney plasma flow trait male 112 days-147 days 8 0.91 ml/min/g 0.08 0.22 inulin analysis by liquid phase colorimetry 0.0 0 109242 3138
MW glomerular filtration rate doxorubicin (2 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. glomerular filtration trait male 0 days 7 0.41 ml/min 0.1 0.26 inulin analysis by liquid phase colorimetry 0.0 doxorubicin 29 days 101207 2581
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male 0 days 5 82.0 nl/min 10.0 22.36 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 sngfr 100609 2479
WKY afferent arteriolar plasma flow rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male 0 days 9 169.0 nl/min 14.0 42.0 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 0 afferent arteriolar plasma flow rate 100530 2479
WKY glomerular capillary hydraulic pressure 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male 0 days 8 47.0 mmHg 2.0 5.66 inulin analysis by liquid phase colorimetry 0.0 0 pgc 100534 2479
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male 0 days 6 0.21 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99959 2378