Phenominer Database Results (46 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Clinical Measurement Notes Record ID Study ID
SS.ZUC-Leprfa+/+/Slc heart ventricle septal wall thickness everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle wall thickness male 91 days 10 0.18 cm 0.0 0.01 echocardiography 0.0 0 101784 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricle end-diastolic diameter control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle end-diastolic diameter male 91 days 8 8.09 mm 0.22 0.62 echocardiography 0.0 0 101787 2641
SS.ZUC-Leprfa+/+/Slc calculated heart left ventricle weight control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle mass male 91 days 8 948.71 mg 51.33 145.18 echocardiography 0.0 0 101795 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricle relative wall thickness bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle wall thickness female 91 days 9 44.0 % 2.0 6.0 echocardiography 0.0 ovariectomy 42 days 101727 2622
SS.ZUC-Leprfa+/+/Slc heart isovolumetric relaxation time bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart muscle relaxation trait female 91 days 9 24.8 ms 1.8 5.4 echocardiography 0.0 ovariectomy 42 days 101735 2622
SS.ZUC-Leprfa+/+/Slc E/A wave ratio everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. blood flow trait male 91 days 10 1.72 null 0.06 0.19 echocardiography 0.0 0 101814 2641
SS.ZUC-Leprfa+/+/Slc E wave deceleration time everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. blood flow trait male 91 days 10 38.2 ms 1.45 4.59 echocardiography 0.0 0 101818 2641
SS.ZUC-Leprfa+/+/Slc heart ventricle septal wall thickness bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle wall thickness female 91 days 12 0.15 cm 0.0 0.01 echocardiography 0.0 ovariectomy 42 days 101708 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricle relative wall thickness everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle wall thickness male 91 days 10 45.0 % 2.0 6.32 echocardiography 0.0 0 101802 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricle posterior wall thickness control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle posterior wall thickness male 91 days 8 1.56 mm 0.09 0.25 echocardiography 0.0 0 101791 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricle posterior wall thickness bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle posterior wall thickness female 91 days 12 1.4 mm 0.02 0.07 echocardiography 0.0 ovariectomy 42 days 101712 2622
SS.ZUC-Leprfa+/+/Slc calculated heart left ventricle weight bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle mass female 91 days 12 589.0 mg 31.0 107.39 echocardiography 0.0 ovariectomy 42 days 101724 2622
SS.ZUC-Leprfa+/+/Slc E wave deceleration time bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart pumping trait female 91 days 12 53.6 ms 1.4 4.85 echocardiography 0.0 ovariectomy 42 days 101732 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricle fractional shortening control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle end-diastolic diameter male 91 days 8 32.62 % 1.67 4.72 echocardiography 0.0 0 101805 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricle fractional shortening everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle end-diastolic diameter male 91 days 10 35.33 % 1.87 5.91 echocardiography 0.0 0 101806 2641
SS.ZUC-Leprfa+/+/Slc heart isovolumetric relaxation time everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart muscle relaxation trait male 91 days 10 31.43 ms 1.47 4.65 echocardiography 0.0 0 101822 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricle fractional shortening bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle end-diastolic diameter female 91 days 9 39.8 % 2.5 7.5 echocardiography 0.0 ovariectomy 42 days 101719 2622
SS.ZUC-Leprfa+/+/Slc E wave deceleration time bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart pumping trait female 91 days 9 35.4 ms 1.2 3.6 echocardiography 0.0 ovariectomy 42 days 101731 2622
SS.ZUC-Leprfa+/+/Slc myocardial performance index bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart pumping trait female 91 days 9 0.44 null 0.01 0.03 echocardiography 0.0 ovariectomy 42 days 101739 2622
SS.ZUC-Leprfa+/+/Slc E wave deceleration time control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. blood flow trait male 91 days 8 33.89 ms 1.4 3.96 echocardiography 0.0 0 101817 2641
SS.ZUC-Leprfa+/+/Slc ejection fraction control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. cardiac output trait male 91 days 8 69.1 % 2.22 6.28 echocardiography 0.0 0 101809 2641
SS.ZUC-Leprfa+/+/Slc E/A wave ratio control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. blood flow trait male 91 days 8 - 1.95 null 0.09 0.25 echocardiography 0.0 0 e/a 101813 2641
SS.ZUC-Leprfa+/+/Slc time constant of left ventricular pressure decay bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricular blood pressure trait female 91 days 12 46.8 ms 2.9 10.05 echocardiography 0.0 ovariectomy 42 days 101748 2622
SS.ZUC-Leprfa+/+/Slc heart ventricle septal wall thickness control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle wall thickness male 91 days 8 0.16 cm 0.01 0.01 echocardiography 0.0 0 101783 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricle end-diastolic diameter everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle end-diastolic diameter male 91 days 10 7.65 mm 0.12 0.38 echocardiography 0.0 0 101788 2641
SS.ZUC-Leprfa+/+/Slc calculated heart left ventricle weight everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle mass male 91 days 10 962.28 mg 30.76 97.27 echocardiography 0.0 0 101796 2641
SS.ZUC-Leprfa+/+/Slc heart ventricle septal wall thickness bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle wall thickness female 91 days 9 0.16 cm 0.0 0.01 echocardiography 0.0 ovariectomy 42 days 101707 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricle posterior wall thickness bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle posterior wall thickness female 91 days 9 1.5 mm 0.02 0.06 echocardiography 0.0 ovariectomy 42 days 101711 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricle end-diastolic diameter bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle end-diastolic diameter female 91 days 9 7.21 mm 0.21 0.63 echocardiography 0.0 ovariectomy 42 days 101715 2622
SS.ZUC-Leprfa+/+/Slc calculated heart left ventricle weight bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle mass female 91 days 9 764.0 mg 27.0 81.0 echocardiography 0.0 ovariectomy 42 days 101723 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricle relative wall thickness control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle wall thickness male 91 days 8 39.0 % 2.0 5.66 echocardiography 0.0 0 101801 2641
SS.ZUC-Leprfa+/+/Slc heart isovolumetric relaxation time control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart muscle relaxation trait male 91 days 8 24.22 ms 2.42 6.84 echocardiography 0.0 0 101821 2641
SS.ZUC-Leprfa+/+/Slc time constant of left ventricular pressure decay control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricular blood pressure trait male 91 days 8 27.47 ms 0.82 2.32 echocardiography 0.0 0 101825 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricular blood pressure trait male 91 days 4 0.56 mmHg/mm 0.04 0.08 echocardiography 0.0 0 lvedp/lvdd 101829 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricular blood pressure trait female 91 days 9 0.32 mmHg/mm 0.02 0.06 echocardiography 0.0 ovariectomy 42 days 101751 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricular blood pressure trait male 91 days 5 0.6 mmHg/mm 0.05 0.11 echocardiography 0.0 0 lvedp/lvdd 101830 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricle posterior wall thickness everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle posterior wall thickness male 91 days 10 1.7 mm 0.06 0.19 echocardiography 0.0 0 101792 2641
SS.ZUC-Leprfa+/+/Slc heart left ventricle end-diastolic diameter bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle end-diastolic diameter female 91 days 12 6.5 mm 0.17 0.59 echocardiography 0.0 ovariectomy 42 days 101716 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricle fractional shortening bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle end-diastolic diameter female 91 days 12 55.2 % 1.9 6.58 echocardiography 0.0 ovariectomy 42 days 101720 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricle relative wall thickness bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle wall thickness female 91 days 12 45.0 % 1.0 3.46 echocardiography 0.0 ovariectomy 42 days 101728 2622
SS.ZUC-Leprfa+/+/Slc heart isovolumetric relaxation time bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart muscle relaxation trait female 91 days 12 39.0 ms 1.0 3.46 echocardiography 0.0 ovariectomy 42 days 101736 2622
SS.ZUC-Leprfa+/+/Slc time constant of left ventricular pressure decay bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricular blood pressure trait female 91 days 9 36.2 ms 0.5 1.5 echocardiography 0.0 ovariectomy 42 days 101747 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricular blood pressure trait female 91 days 12 0.63 mmHg/mm 0.05 0.17 echocardiography 0.0 ovariectomy 42 days 101752 2622
SS.ZUC-Leprfa+/+/Slc ejection fraction everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. cardiac output trait male 91 days 10 72.2 % 2.34 7.4 echocardiography 0.0 0 101810 2641
SS.ZUC-Leprfa+/+/Slc time constant of left ventricular pressure decay everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricular blood pressure trait male 91 days 10 29.01 ms 2.59 8.19 echocardiography 0.0 0 101826 2641
SS.ZUC-Leprfa+/+/Slc myocardial performance index bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart pumping trait female 91 days 12 0.57 null 0.03 0.1 echocardiography 0.0 ovariectomy 42 days 101740 2622