Phenominer Database Results (172 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
BN/Cub serum triglyceride level controlled sucrose content diet (for 7 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood triglyceride amount male 307 days 6 61.95 mg/dl 7.23 17.7 liquid phase colorimetry retroorbital plexus 0.0 0 70216 1318
PD/Cub serum triglyceride level controlled sucrose content diet (for 7 days) then dexamethasone (0.03 mg/ml) (for 3 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood triglyceride amount male 310 days 6 2412.4 mg/dl 173.42 424.78 liquid phase colorimetry retroorbital plexus 0.0 0 70219 1318
BN/Cub serum triglyceride level controlled sucrose content diet (for 7 days) then dexamethasone (0.03 mg/ml) (for 3 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood triglyceride amount male 310 days 6 46.9 mg/dl 3.61 8.85 liquid phase colorimetry retroorbital plexus 0.0 0 70220 1318
PD/Cub serum free fatty acids level controlled sucrose content diet (for 7 days) then dexamethasone (0.03 mg/ml) (for 3 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood free fatty acid amount male 310 days 6 4.13 mmol/l 0.12 0.3 liquid phase colorimetry retroorbital plexus 0.0 0 70234 1318
SHR.PD-(D8Mgh9-D8Rat149)/Cub serum free fatty acids level fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood free fatty acid amount male 0 days 6 1.58 mmol/l 0.04 0.09 liquid phase colorimetry retroorbital plexus 0.0 0 70289 1318
Hsd:WI serum total protein level vehicle control condition (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood total protein amount male 119 days-126 days 5 9.38 g/dl 0.67 1.5 liquid phase colorimetry 0.0 0 76125 1545
Hsd:WI serum total protein level bisphenol A (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood total protein amount male 119 days-126 days 6 7.12 g/dl 0.19 0.45 liquid phase colorimetry 0.0 0 76127 1545
Hsd:WI serum total protein level octylphenol (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood total protein amount male 119 days-126 days 6 8.18 g/dl 0.21 0.52 liquid phase colorimetry 0.0 0 76128 1545
Hsd:WI serum total protein level octylphenol (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood total protein amount male 119 days-126 days 6 7.37 g/dl 0.12 0.29 liquid phase colorimetry 0.0 0 76129 1545
Crl:SD plasma glucose level controlled metformin content drinking water (350-500 mg/kg/d) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 42 days 8 106.2 mg/dl 9.0 25.46 liquid phase colorimetry 0.0 0 CT 75862 1540
Hsd:WI plasma creatinine level phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood creatinine amount male 0 days 8 0.31 mg/dl 0.02 0.05 liquid phase colorimetry 0.0 0 75943 1542
Hsd:WI kidney catalase activity to total protein level ratio silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. catalase activity male 0 days 6 30.56 nmol/mg 0.37 0.9 liquid phase colorimetry 0.0 0 76237 1544
Hsd:WI serum triglyceride level vehicle control condition (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood triglyceride amount male 119 days-126 days 5 156.94 mg/dl 14.93 33.39 liquid phase colorimetry 0.0 0 76135 1545
Hsd:WI serum calcium level bisphenol A (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood calcium amount male 119 days-126 days 6 12.93 mg/dl 0.78 1.91 liquid phase colorimetry 0.0 0 76142 1545
Hsd:WI serum urea nitrogen level vehicle control condition (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood urea nitrogen amount male 119 days-126 days 5 77.76 mg/dl 3.18 7.11 liquid phase colorimetry 0.0 0 76164 1545
Hsd:WI serum lactate dehydrogenase activity level bisphenol A (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood lactate dehydrogenase amount male 119 days-126 days 6 1036.8 U/l 158.11 387.3 liquid phase colorimetry 0.0 0 76179 1545
Hsd:WI kidney superoxide dismutase activity to total protein level ratio vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney superoxide dismutase activity male 0 days 6 8.13 U/mg 0.79 1.94 liquid phase colorimetry 0.0 0 76188 1544
Hsd:WI serum urea nitrogen level silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood urea nitrogen amount male 0 days 6 75.2 mg/dl 2.16 5.3 liquid phase colorimetry 0.0 0 75979 1544
Hsd:WI kidney superoxide dismutase to glutathione peroxidase ratio benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 8.49 null 0.4 1.14 liquid phase colorimetry 0.0 0 76222 1542
Jcl:WI serum total cholesterol level control condition Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. blood cholesterol amount male 52 days 6 80.7 mg/dl 6.58 16.12 liquid phase colorimetry 0.0 0 103962 2884
Jcl:WI serum high density lipoprotein cholesterol level to serum total cholesterol level ratio control condition Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. blood cholesterol amount male 52 days 6 0.81 null 0.02 0.05 liquid phase colorimetry 0.0 0 103966 2884
GK/Jcl serum high density lipoprotein cholesterol level to serum total cholesterol level ratio control condition Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. blood cholesterol amount male 52 days 6 0.61 null 0.02 0.05 liquid phase colorimetry 0.0 0 103967 2884
GK/Jcl serum high density lipoprotein cholesterol level to serum total cholesterol level ratio controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. blood cholesterol amount male 52 days 6 0.9 null 0.07 0.17 liquid phase colorimetry 0.0 0 103969 2884
GK/Jcl liver cholesterol level controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. liver cholesterol amount male 52 days 6 1.67 mg/g 0.06 0.15 liquid phase colorimetry 0.0 0 103977 2884
SD-Abcc6em2Qlju-/- serum phosphate level standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount female 60 days-180 days 5 5.9 mg/dl 0.2 0.45 liquid phase colorimetry 0.0 0 104647 2972
SD-Abcc6em2Qlju+/+ serum phosphate level to serum pyrophosphate ratio standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount female 60 days-180 days 5 558.9 null 97.9 218.91 liquid phase colorimetry 0.0 0 104661 2972
MWF renal filtration fraction castor oil Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. glomerular filtration trait male 133 days-147 days 7 0.25 null 0.03 0.08 liquid phase colorimetry 0.0 0 110085 3163
DA/BklArbNsi inflammatory exudate nitric oxide level room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. nitric oxide amount female 56 days-98 days 9 median 0.11 umol/l liquid phase colorimetry subcutaneous interscapular cavity 0.0 0 Griess test inflammatory exudate nitric oxide measurement 68403 332
Hsd:WI kidney superoxide dismutase activity to total protein level ratio vehicle control condition (for 10 days) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney superoxide dismutase activity male 0 days 6 13.53 U/mg 0.8 1.97 liquid phase colorimetry 0.0 0 76187 1544
Hsd:WI serum total cholesterol level octylphenol (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood cholesterol amount male 119 days-126 days 6 61.15 mg/dl 2.86 7.0 liquid phase colorimetry 0.0 0 76134 1545
Hsd:WI serum calcium level octylphenol (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood calcium amount male 119 days-126 days 6 12.68 mg/dl 0.31 0.76 liquid phase colorimetry 0.0 0 76145 1545
Hsd:WI serum total cholesterol level vehicle control condition (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood cholesterol amount male 119 days-126 days 5 68.12 mg/dl 6.42 14.36 liquid phase colorimetry 0.0 0 76130 1545
Hsd:WI serum total cholesterol level octylphenol (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood cholesterol amount male 119 days-126 days 6 62.85 mg/dl 3.03 7.43 liquid phase colorimetry 0.0 0 76133 1545
Hsd:WI plasma uric acid level cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood uric acid amount male 0 days 8 7.67 mg/dl 0.55 1.55 liquid phase colorimetry 0.0 0 75949 1542
Hsd:WI kidney superoxide dismutase to paraoxonase1 activity ratio phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 13.88 null 0.5 1.41 liquid phase colorimetry 0.0 0 76225 1542
BN/Cub serum free fatty acids level controlled sucrose content diet (for 7 days) then dexamethasone (0.03 mg/ml) (for 3 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood free fatty acid amount male 310 days 6 1.4 mmol/l 0.08 0.2 liquid phase colorimetry retroorbital plexus 0.0 0 70235 1318
Hsd:WI kidney lipid peroxide level silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney lipid peroxide amount male 0 days 6 0.88 nmol/mg 0.02 0.06 liquid phase colorimetry 0.0 0 76259 1544
PD/Cub serum triglyceride level controlled sucrose content diet (for 7 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood triglyceride amount male 307 days 6 276.99 mg/dl 43.35 106.2 liquid phase colorimetry retroorbital plexus 0.0 0 70215 1318
Hsd:WI serum urea nitrogen level 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood urea nitrogen amount male 0 days 6 89.7 mg/dl 2.9 7.11 liquid phase colorimetry 0.0 0 75978 1544
PD/Cub serum triglyceride level fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood triglyceride amount male 300 days 6 178.76 mg/dl 18.06 44.25 liquid phase colorimetry retroorbital plexus 0.0 0 70213 1318
Crl:SD plasma glucose level control condition Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 63 days-77 days 8 111.6 mg/dl 1.8 5.09 liquid phase colorimetry 0.0 0 C 75856 1540
Crl:SD plasma glucose level controlled fructose content diet (66 %) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 42 days 9 108.0 mg/dl 1.8 5.4 liquid phase colorimetry 0.0 0 F 75859 1540
Hsd:WI kidney glutathione peroxidase activity to total protein level ratio vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione peroxidase activity male 0 days 6 7.54 U/mg 0.51 1.24 liquid phase colorimetry 0.0 0 76192 1544
Hsd:WI kidney glutathione peroxidase activity to total protein level ratio silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione peroxidase activity male 0 days 6 15.4 U/mg 0.29 0.71 liquid phase colorimetry 0.0 0 76194 1544
Hsd:WI serum triglyceride level octylphenol (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood triglyceride amount male 119 days-126 days 6 111.38 mg/dl 14.75 36.14 liquid phase colorimetry 0.0 0 76139 1545
Hsd:WI serum calcium level vehicle control condition (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood calcium amount male 119 days-126 days 5 12.82 mg/dl 0.24 0.53 liquid phase colorimetry 0.0 0 76141 1545
Hsd:WI serum albumin level vehicle control condition (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood albumin amount male 119 days-126 days 5 0.04 g/dl 0.0 0.0 liquid phase colorimetry 0.0 0 76149 1545
Hsd:WI serum albumin level octylphenol (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood albumin amount male 119 days-126 days 6 0.04 g/dl 0.0 0.0 liquid phase colorimetry 0.0 0 76153 1545
Hsd:WI serum urea nitrogen level bisphenol A (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood urea nitrogen amount male 119 days-126 days 6 72.5 mg/dl 4.18 10.25 liquid phase colorimetry 0.0 0 76166 1545
Hsd:WI plasma creatinine level cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood creatinine amount male 0 days 8 1.67 mg/dl 0.12 0.33 liquid phase colorimetry 0.0 0 75946 1542
Hsd:WI kidney superoxide dismutase activity to total protein level ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 450.1 U/mg 3.15 8.91 liquid phase colorimetry 0.0 0 76201 1542
Hsd:WI kidney paraoxonase1 activity to total protein level ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney paraoxonase 1 activity male 0 days 8 9.57 U/mg 0.3 0.86 liquid phase colorimetry 0.0 0 76211 1542
Hsd:WI kidney glutathione peroxidase activity to glutathione reductase activity ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione peroxidase activity male 0 days 8 62.54 null 2.21 6.24 liquid phase colorimetry 0.0 0 76215 1542
Hsd:WI serum urea nitrogen level vehicle control condition (for 10 days) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood urea nitrogen amount male 0 days 6 69.64 mg/dl 2.5 6.12 liquid phase colorimetry 0.0 0 75976 1544
Hsd:WI serum urea nitrogen level vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood urea nitrogen amount male 0 days 6 96.11 mg/dl 1.91 4.69 liquid phase colorimetry 0.0 0 75977 1544
Hsd:WI kidney superoxide dismutase to catalase activity ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 6.67 null 0.3 0.85 liquid phase colorimetry 0.0 0 76219 1542
Hsd:WI kidney superoxide dismutase to paraoxonase1 activity ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 47.04 null 2.0 5.65 liquid phase colorimetry 0.0 0 76227 1542
GK/Jcl serum total cholesterol level controlled hesperidin content diet (1 %) (for 28 days) Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. blood cholesterol amount male 52 days 6 117.47 mg/dl 4.36 10.68 liquid phase colorimetry 0.0 0 103964 2884
GK/Jcl serum total cholesterol level controlled cyclodextrin (CD)-clathrated hesperetin content diet (4.6 %) (for 28 days) Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. blood cholesterol amount male 52 days 6 86.45 mg/dl 3.98 9.75 liquid phase colorimetry 0.0 0 103965 2884
SD-Abcc6em2Qlju+/- serum phosphate level standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount male 60 days-180 days 5 7.1 mg/dl 0.6 1.34 liquid phase colorimetry 0.0 0 104644 2972
SD-Abcc6em2Qlju-/- serum phosphate level to serum pyrophosphate ratio standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount male 60 days-180 days 5 2082.3 null 626.9 1401.79 liquid phase colorimetry 0.0 0 104664 2972
MWF renal plasma flow castor oil Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. kidney plasma flow trait male 133 days-147 days 7 3.73 ml/min 0.35 0.93 liquid phase colorimetry 0.0 0 110082 3163
MWF renal plasma flow cyclosporine A (50 ml/kg/d) (for 7 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. kidney plasma flow trait male 133 days-147 days 6 2.58 ml/min 0.1 0.24 liquid phase colorimetry 0.0 0 110083 3163
Hsd:WI serum total bilirubin level vehicle control condition (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood bilirubin amount male 119 days-126 days 5 0.96 mg/dl 0.07 0.17 liquid phase colorimetry 0.0 0 76156 1545
Hsd:WI kidney superoxide dismutase activity to total protein level ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 292.4 U/mg 14.25 40.3 liquid phase colorimetry 0.0 0 76202 1542
SD-Abcc6em2Qlju+/+ serum phosphate level to serum pyrophosphate ratio standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount male 60 days-180 days 5 455.3 null 54.2 121.19 liquid phase colorimetry 0.0 0 104660 2972
Hsd:WI kidney superoxide dismutase to paraoxonase1 activity ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 19.72 null 0.82 2.31 liquid phase colorimetry 0.0 0 76228 1542
PD/Cub serum uric acid level fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood uric acid amount male 300 days 6 66.6 umol/l 0.57 1.4 liquid phase colorimetry retroorbital plexus 0.0 0 70280 1318
PD/Cub serum uric acid level controlled sucrose content diet (for 7 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood uric acid amount male 307 days 6 110.2 umol/l 2.49 6.1 liquid phase colorimetry retroorbital plexus 0.0 0 70282 1318
F344/NHsd inflammatory exudate nitric oxide level room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. nitric oxide amount female 56 days-98 days 10 median 0.12 umol/l liquid phase colorimetry subcutaneous interscapular cavity 0.0 0 Griess test inflammatory exudate nitric oxide measurement 68404 332
DA.F344-(D8Arb15-D8Arb22)/Arb inflammatory exudate nitric oxide level room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. nitric oxide amount female 56 days-98 days 14 median 0.16 umol/l liquid phase colorimetry subcutaneous interscapular cavity 0.0 0 Griess test inflammatory exudate nitric oxide measurement 68405 332
Hsd:WI serum total cholesterol level bisphenol A (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood cholesterol amount male 119 days-126 days 6 66.62 mg/dl 5.62 13.77 liquid phase colorimetry 0.0 0 76131 1545
Hsd:WI serum total cholesterol level bisphenol A (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood cholesterol amount male 119 days-126 days 6 56.48 mg/dl 4.25 10.4 liquid phase colorimetry 0.0 0 76132 1545
Crl:SD plasma glucose level control condition Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 42 days 8 118.8 mg/dl 5.4 15.27 liquid phase colorimetry 0.0 0 C 75860 1540
Hsd:WI kidney glutathione peroxidase activity to total protein level ratio vehicle control condition (for 10 days) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione peroxidase activity male 0 days 6 22.63 U/mg 1.35 3.3 liquid phase colorimetry 0.0 0 76191 1544
Hsd:WI kidney glutathione peroxidase activity to total protein level ratio 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione peroxidase activity male 0 days 6 13.39 U/mg 0.09 0.21 liquid phase colorimetry 0.0 0 76193 1544
Hsd:WI kidney lipid peroxide level vehicle control condition (for 10 days) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney lipid peroxide amount male 0 days 6 0.75 nmol/mg 0.02 0.04 liquid phase colorimetry 0.0 0 76256 1544
Hsd:WI kidney lipid peroxide level 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney lipid peroxide amount male 0 days 6 0.83 nmol/mg 0.04 0.09 liquid phase colorimetry 0.0 0 76258 1544
Hsd:WI plasma urea nitrogen level phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood urea nitrogen amount male 0 days 8 8.7 mmol/l 0.47 1.34 liquid phase colorimetry 0.0 0 75939 1542
Hsd:WI plasma uric acid level benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood uric acid amount male 0 days 8 2.79 mg/dl 0.18 0.52 liquid phase colorimetry 0.0 0 75948 1542
Hsd:WI kidney glutathione level cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione amount male 0 days 8 108.4 ug/g 4.56 12.9 liquid phase colorimetry 0.0 0 76232 1542
Hsd:WI kidney catalase activity to total protein level ratio vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. catalase activity male 0 days 6 21.73 nmol/mg 0.62 1.51 liquid phase colorimetry 0.0 0 76235 1544
Hsd:WI serum calcium level octylphenol (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood calcium amount male 119 days-126 days 6 12.98 mg/dl 0.42 1.04 liquid phase colorimetry 0.0 0 76144 1545
Hsd:WI serum urea nitrogen level octylphenol (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood urea nitrogen amount male 119 days-126 days 6 72.18 mg/dl 5.06 12.4 liquid phase colorimetry 0.0 0 76168 1545
Hsd:WI serum creatinine level bisphenol A (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood creatinine amount male 119 days-126 days 6 0.65 mg/dl 0.03 0.08 liquid phase colorimetry 0.0 0 76171 1545
Hsd:WI serum creatinine level octylphenol (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood creatinine amount male 119 days-126 days 6 0.68 mg/dl 0.03 0.08 liquid phase colorimetry 0.0 0 76174 1545
Hsd:WI serum lactate dehydrogenase activity level vehicle control condition (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood lactate dehydrogenase amount male 119 days-126 days 5 1068.0 U/l 313.23 700.4 liquid phase colorimetry 0.0 0 76177 1545
Hsd:WI kidney superoxide dismutase activity to total protein level ratio phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 239.5 U/mg 7.28 20.6 liquid phase colorimetry 0.0 0 76199 1542
Hsd:WI kidney paraoxonase1 activity to total protein level ratio benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney paraoxonase 1 activity male 0 days 8 19.45 U/mg 0.75 2.13 liquid phase colorimetry 0.0 0 76210 1542
Hsd:WI kidney glutathione level cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione amount male 0 days 8 58.72 ug/g 3.78 10.7 liquid phase colorimetry 0.0 0 76231 1542
GK/Jcl serum high density lipoprotein cholesterol level to serum total cholesterol level ratio controlled hesperidin content diet (1 %) (for 28 days) Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. blood cholesterol amount male 52 days 6 0.94 null 0.02 0.05 liquid phase colorimetry 0.0 0 103968 2884
GK/Jcl liver cholesterol level controlled hesperidin content diet (1 %) (for 28 days) Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. liver cholesterol amount male 52 days 6 1.82 mg/g 0.13 0.32 liquid phase colorimetry 0.0 0 103976 2884
SD-Abcc6em2Qlju+/+ serum phosphate level standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount male 60 days-180 days 5 7.0 mg/dl 0.3 0.67 liquid phase colorimetry 0.0 0 104642 2972
SD-Abcc6em2Qlju+/- serum phosphate level to serum pyrophosphate ratio standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount male 60 days-180 days 5 820.6 null 144.1 322.22 liquid phase colorimetry 0.0 0 104662 2972
MWF renal plasma flow cyclosporine A (50 ml/kg/d) (for 7 days) and lacidipine (1 mg/kg/d) (for 7 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. kidney plasma flow trait male 133 days-147 days 7 3.56 ml/min 0.46 1.23 liquid phase colorimetry 0.0 0 110084 3163
Hsd:WI plasma urea nitrogen level cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood urea nitrogen amount male 0 days 8 20.62 mmol/l 1.27 3.61 liquid phase colorimetry 0.0 0 75941 1542
Hsd:WI serum total bilirubin level octylphenol (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood bilirubin amount male 119 days-126 days 6 0.53 mg/dl 0.08 0.21 liquid phase colorimetry 0.0 0 76159 1545
Hsd:WI serum urea nitrogen level bisphenol A (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood urea nitrogen amount male 119 days-126 days 6 80.85 mg/dl 3.23 7.92 liquid phase colorimetry 0.0 0 76165 1545
Hsd:WI serum lactate dehydrogenase activity level bisphenol A (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood lactate dehydrogenase amount male 119 days-126 days 6 754.8 U/l 112.47 275.5 liquid phase colorimetry 0.0 0 76178 1545
Hsd:WI kidney catalase activity to total protein level ratio vehicle control condition (for 10 days) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. catalase activity male 0 days 6 35.98 nmol/mg 0.81 1.98 liquid phase colorimetry 0.0 0 76234 1544
Hsd:WI kidney glutathione peroxidase activity to glutathione reductase activity ratio phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione peroxidase activity male 0 days 8 59.12 null 1.93 5.47 liquid phase colorimetry 0.0 0 76213 1542
Hsd:WI kidney glutathione peroxidase activity to glutathione reductase activity ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione peroxidase activity male 0 days 8 46.14 null 1.7 4.82 liquid phase colorimetry 0.0 0 76216 1542
Crl:SD plasma glucose level controlled metformin content drinking water (350-500 mg/kg/d) then controlled fructose content diet (66 %) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 42 days 10 104.4 mg/dl 9.0 28.46 liquid phase colorimetry 0.0 0 FT 75861 1540
Hsd:WI kidney lipid peroxide level vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney lipid peroxide amount male 0 days 6 1.51 nmol/mg 0.03 0.08 liquid phase colorimetry 0.0 0 76257 1544
SD-Abcc6em2Qlju+/+ serum phosphate level standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount female 60 days-180 days 5 5.9 mg/dl 0.2 0.45 liquid phase colorimetry 0.0 0 104643 2972
SD-Abcc6em2Qlju-/- serum phosphate level to serum pyrophosphate ratio standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount female 60 days-180 days 5 1925.5 null 479.2 1071.52 liquid phase colorimetry 0.0 0 104665 2972
BN/Cub serum uric acid level fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood uric acid amount male 300 days 6 72.3 umol/l 1.55 3.8 liquid phase colorimetry retroorbital plexus 0.0 0 70281 1318
BN/Cub serum uric acid level controlled sucrose content diet (for 7 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood uric acid amount male 307 days 6 101.8 umol/l 4.78 11.7 liquid phase colorimetry retroorbital plexus 0.0 0 70283 1318
PD/Cub serum uric acid level controlled sucrose content diet (for 7 days) then dexamethasone (0.03 mg/ml) (for 3 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood uric acid amount male 310 days 6 67.2 umol/l 2.53 6.2 liquid phase colorimetry retroorbital plexus 0.0 0 70284 1318
BN/Cub serum free fatty acids level controlled sucrose content diet (for 7 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood free fatty acid amount male 307 days 6 1.26 mmol/l 0.08 0.2 liquid phase colorimetry retroorbital plexus 0.0 0 70231 1318
Crl:SD plasma glucose level controlled fructose content diet (66 %) (between 14 and 28 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 63 days-77 days 9 117.0 mg/dl 3.6 10.8 liquid phase colorimetry 0.0 0 F 75855 1540
Crl:SD plasma glucose level controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 63 days-77 days 10 111.6 mg/dl 1.8 5.69 liquid phase colorimetry 0.0 0 FT 75857 1540
Hsd:WI plasma creatinine level cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood creatinine amount male 0 days 8 2.85 mg/dl 0.25 0.71 liquid phase colorimetry 0.0 0 75945 1542
Hsd:WI serum triglyceride level bisphenol A (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood triglyceride amount male 119 days-126 days 6 116.97 mg/dl 7.02 17.2 liquid phase colorimetry 0.0 0 76136 1545
Hsd:WI serum total bilirubin level bisphenol A (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood bilirubin amount male 119 days-126 days 6 0.75 mg/dl 0.26 0.64 liquid phase colorimetry 0.0 0 76158 1545
Hsd:WI serum total bilirubin level octylphenol (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood bilirubin amount male 119 days-126 days 6 0.55 mg/dl 0.08 0.21 liquid phase colorimetry 0.0 0 76160 1545
Hsd:WI kidney superoxide dismutase activity to total protein level ratio benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 242.2 U/mg 5.3 15.0 liquid phase colorimetry 0.0 0 76200 1542
Hsd:WI kidney paraoxonase1 activity to total protein level ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney paraoxonase 1 activity male 0 days 8 14.83 U/mg 0.43 1.21 liquid phase colorimetry 0.0 0 76212 1542
Hsd:WI kidney superoxide dismutase to catalase activity ratio phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 1.98 null 0.07 0.21 liquid phase colorimetry 0.0 0 76217 1542
Hsd:WI kidney superoxide dismutase to glutathione peroxidase ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 18.63 null 0.61 1.73 liquid phase colorimetry 0.0 0 76224 1542
Hsd:WI kidney glutathione level phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione amount male 0 days 8 123.7 ug/g 1.78 5.04 liquid phase colorimetry 0.0 0 76229 1542
Crl:SD plasma glucose level controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 0 days 8 102.6 mg/dl 3.6 10.18 liquid phase colorimetry 0.0 0 FT 75921 1540
GK/Jcl liver cholesterol level control condition Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. liver cholesterol amount male 52 days 6 2.62 mg/g 0.08 0.2 liquid phase colorimetry 0.0 0 103975 2884
Hsd:WI serum calcium level bisphenol A (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood calcium amount male 119 days-126 days 6 11.98 mg/dl 0.18 0.45 liquid phase colorimetry 0.0 0 76143 1545
Hsd:WI serum albumin level bisphenol A (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood albumin amount male 119 days-126 days 6 0.04 g/dl 0.0 0.0 liquid phase colorimetry 0.0 0 76151 1545
Hsd:WI serum creatinine level vehicle control condition (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood creatinine amount male 119 days-126 days 5 0.68 mg/dl 0.05 0.11 liquid phase colorimetry 0.0 0 76170 1545
Hsd:WI kidney glutathione level 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione amount male 0 days 6 10012.49 ug/g 293.58 719.13 liquid phase colorimetry 0.0 0 76240 1544
Hsd:WI kidney glutathione level vehicle control condition (for 10 days) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione amount male 0 days 6 12385.0 ug/g 257.2 630.01 liquid phase colorimetry 0.0 0 76238 1544
BN/Cub serum free fatty acids level fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood free fatty acid amount male 300 days 6 1.12 mmol/l 0.08 0.2 liquid phase colorimetry retroorbital plexus 0.0 0 70229 1318
SHR/OlaIpcv serum free fatty acids level fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood free fatty acid amount male 0 days 6 1.28 mmol/l 0.02 0.04 liquid phase colorimetry retroorbital plexus 0.0 0 70288 1318
SD-Abcc6em2Qlju-/- serum phosphate level standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount male 60 days-180 days 5 7.1 mg/dl 0.5 1.12 liquid phase colorimetry 0.0 0 104646 2972
Hsd:WI kidney glutathione peroxidase activity to glutathione reductase activity ratio benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione peroxidase activity male 0 days 8 54.88 null 1.74 4.93 liquid phase colorimetry 0.0 0 76214 1542
BN/Cub serum triglyceride level fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood triglyceride amount male 300 days 6 47.79 mg/dl 3.61 8.85 liquid phase colorimetry retroorbital plexus 0.0 0 70214 1318
PD/Cub serum free fatty acids level fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood free fatty acid amount male 300 days 6 1.05 mmol/l 0.04 0.1 liquid phase colorimetry retroorbital plexus 0.0 0 70228 1318
PD/Cub serum free fatty acids level controlled sucrose content diet (for 7 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood free fatty acid amount male 307 days 6 1.56 mmol/l 0.04 0.1 liquid phase colorimetry retroorbital plexus 0.0 0 70230 1318
BN/Cub serum uric acid level controlled sucrose content diet (for 7 days) then dexamethasone (0.03 mg/ml) (for 3 days) then fasting (for 16 hours) Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. blood uric acid amount male 310 days 6 107.3 umol/l 3.18 7.8 liquid phase colorimetry retroorbital plexus 0.0 0 70285 1318
Hsd:WI serum total protein level bisphenol A (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood total protein amount male 119 days-126 days 6 8.68 g/dl 0.78 1.9 liquid phase colorimetry 0.0 0 76126 1545
Crl:SD plasma glucose level controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 63 days-77 days 8 111.6 mg/dl 5.4 15.27 liquid phase colorimetry 0.0 0 CT 75858 1540
Hsd:WI serum triglyceride level octylphenol (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood triglyceride amount male 119 days-126 days 6 109.72 mg/dl 16.57 40.58 liquid phase colorimetry 0.0 0 76138 1545
Hsd:WI serum albumin level bisphenol A (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood albumin amount male 119 days-126 days 6 0.05 g/dl 0.0 0.01 liquid phase colorimetry 0.0 0 76150 1545
Hsd:WI serum albumin level octylphenol (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood albumin amount male 119 days-126 days 6 0.05 g/dl 0.0 0.0 liquid phase colorimetry 0.0 0 76152 1545
Hsd:WI serum total bilirubin level bisphenol A (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood bilirubin amount male 119 days-126 days 6 0.6 mg/dl 0.13 0.32 liquid phase colorimetry 0.0 0 76157 1545
Hsd:WI serum creatinine level bisphenol A (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood creatinine amount male 119 days-126 days 6 0.65 mg/dl 0.03 0.08 liquid phase colorimetry 0.0 0 76172 1545
Hsd:WI serum lactate dehydrogenase activity level octylphenol (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood lactate dehydrogenase amount male 119 days-126 days 6 659.2 U/l 70.1 171.7 liquid phase colorimetry 0.0 0 76180 1545
Hsd:WI plasma uric acid level cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood uric acid amount male 0 days 8 4.89 mg/dl 0.35 0.98 liquid phase colorimetry 0.0 0 75950 1542
Hsd:WI kidney paraoxonase1 activity to total protein level ratio phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney paraoxonase 1 activity male 0 days 8 17.25 U/mg 0.61 1.73 liquid phase colorimetry 0.0 0 76209 1542
Hsd:WI kidney glutathione level vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione amount male 0 days 6 7882.76 ug/g 178.16 436.39 liquid phase colorimetry 0.0 0 76239 1544
Hsd:WI kidney superoxide dismutase activity to total protein level ratio silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney superoxide dismutase activity male 0 days 6 11.74 U/mg 0.56 1.38 liquid phase colorimetry 0.0 0 76190 1544
Hsd:WI kidney superoxide dismutase to glutathione peroxidase ratio phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 8.66 null 0.41 1.15 liquid phase colorimetry 0.0 0 76221 1542
Hsd:WI kidney glutathione level silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney glutathione amount male 0 days 6 9864.97 ug/g 200.74 491.71 liquid phase colorimetry 0.0 0 76241 1544
GK/Jcl serum total cholesterol level control condition Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. blood cholesterol amount male 52 days 6 182.95 mg/dl 5.35 13.1 liquid phase colorimetry 0.0 0 103963 2884
Jcl:WI liver cholesterol level control condition Akiyama S, et al., Biosci Biotechnol Biochem. 2009 Dec;73(12):2779-82. doi: 10.1271/bbb.90576. Epub 2009 Dec 7. liver cholesterol amount male 52 days 6 1.88 mg/g 0.15 0.37 liquid phase colorimetry 0.0 0 103974 2884
SD-Abcc6em2Qlju+/- serum phosphate level standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount female 60 days-180 days 5 5.7 mg/dl 0.1 0.22 liquid phase colorimetry 0.0 0 104645 2972
MWF renal filtration fraction cyclosporine A (50 ml/kg/d) (for 7 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. glomerular filtration trait male 133 days-147 days 6 0.18 null 0.02 0.04 liquid phase colorimetry 0.0 0 110086 3163
MWF renal filtration fraction cyclosporine A (50 ml/kg/d) (for 7 days) and lacidipine (1 mg/kg/d) (for 7 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. glomerular filtration trait male 133 days-147 days 7 0.24 null 0.03 0.08 liquid phase colorimetry 0.0 0 110087 3163
Hsd:WI plasma urea nitrogen level benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood urea nitrogen amount male 0 days 8 8.05 mmol/l 0.44 1.25 liquid phase colorimetry 0.0 0 75940 1542
Hsd:WI kidney superoxide dismutase activity to total protein level ratio 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. kidney superoxide dismutase activity male 0 days 6 10.11 U/mg 0.22 0.54 liquid phase colorimetry 0.0 0 76189 1544
Hsd:WI serum triglyceride level bisphenol A (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood triglyceride amount male 119 days-126 days 6 92.87 mg/dl 11.85 29.03 liquid phase colorimetry 0.0 0 76137 1545
Hsd:WI serum urea nitrogen level octylphenol (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood urea nitrogen amount male 119 days-126 days 6 76.42 mg/dl 4.07 9.96 liquid phase colorimetry 0.0 0 76167 1545
Hsd:WI serum creatinine level octylphenol (125 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood creatinine amount male 119 days-126 days 6 0.55 mg/dl 0.04 0.11 liquid phase colorimetry 0.0 0 76173 1545
Hsd:WI serum lactate dehydrogenase activity level octylphenol (250 mg/kg/d) (for 91 days) Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. blood lactate dehydrogenase amount male 119 days-126 days 6 919.2 U/l 186.98 458.0 liquid phase colorimetry 0.0 0 76181 1545
Hsd:WI plasma urea nitrogen level cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood urea nitrogen amount male 0 days 8 14.48 mmol/l 0.88 2.49 liquid phase colorimetry 0.0 0 75942 1542
Hsd:WI plasma creatinine level benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood creatinine amount male 0 days 8 0.27 mg/dl 0.02 0.05 liquid phase colorimetry 0.0 0 75944 1542
Hsd:WI plasma uric acid level phosphate buffered saline (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. blood uric acid amount male 0 days 8 2.97 mg/dl 0.18 0.51 liquid phase colorimetry 0.0 0 75947 1542
Hsd:WI kidney catalase activity to total protein level ratio 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. catalase activity male 0 days 6 23.2 nmol/mg 0.29 0.7 liquid phase colorimetry 0.0 0 76236 1544
Hsd:WI kidney superoxide dismutase to catalase activity ratio benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 1.93 null 0.07 0.2 liquid phase colorimetry 0.0 0 76218 1542
Crl:SD plasma glucose level controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. blood glucose amount male 0 days 8 82.8 mg/dl 7.2 20.36 liquid phase colorimetry 0.0 0 FT 75922 1540
SD-Abcc6em2Qlju+/- serum phosphate level to serum pyrophosphate ratio standard diet Li Q, et al., J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. blood phosphate amount female 60 days-180 days 5 710.9 null 48.5 108.45 liquid phase colorimetry 0.0 0 104663 2972
Hsd:WI kidney superoxide dismutase to catalase activity ratio cisplatin (3 mg/kg) (for 25 days) and benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 2.92 null 0.11 0.32 liquid phase colorimetry 0.0 0 76220 1542
Hsd:WI kidney superoxide dismutase to glutathione peroxidase ratio cisplatin (3 mg/kg) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 35.78 null 1.46 4.14 liquid phase colorimetry 0.0 0 76223 1542
Hsd:WI kidney superoxide dismutase to paraoxonase1 activity ratio benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney superoxide dismutase activity male 0 days 8 12.45 null 0.43 1.23 liquid phase colorimetry 0.0 0 76226 1542
Hsd:WI kidney glutathione level benfotiamine (100 mg/kg/d) (for 25 days) Harisa GI J Biochem Mol Toxicol. 2013 Aug;27(8):398-405. doi: 10.1002/jbt.21501. Epub 2013 May 28. kidney glutathione amount male 0 days 8 126.5 ug/g 1.5 4.23 liquid phase colorimetry 0.0 0 76230 1542