BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
male |
87 days-120 days |
3 |
1.39 |
ml/min |
0.23 |
0.41 |
urine creatinine analysis |
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51063 |
481 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
glomerular filtration trait |
male |
87 days-120 days |
3 |
1.49 |
ml/min |
0.16 |
0.28 |
urine creatinine analysis |
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51955 |
481 |
BN/NHsdMcwi |
urine creatinine level |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine creatinine amount |
female |
89 days-92 days |
24 |
30.2 |
mg/dl |
3.87 |
18.96 |
urine creatinine analysis |
0.0 |
0 |
|
|
|
69455 |
151 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
glomerular filtration trait |
female |
80 days-99 days |
7 |
1.23 |
ml/min |
0.15 |
0.4 |
urine creatinine analysis |
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52380 |
482 |
BN/NHsdMcwi |
urine creatinine excretion rate |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine creatinine amount |
female |
92 days-94 days |
25 |
0.0 |
mg/d |
0.0 |
0.0 |
urine creatinine analysis |
0.0 |
0 |
|
mg/min |
|
69477 |
151 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
glomerular filtration trait |
female |
87 days-120 days |
6 |
1.28 |
ml/min |
0.07 |
0.17 |
urine creatinine analysis |
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51956 |
481 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
glomerular filtration trait |
male |
80 days-99 days |
8 |
2.55 |
ml/min |
0.26 |
0.72 |
urine creatinine analysis |
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52379 |
482 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
glomerular filtration trait |
female |
90 days-94 days |
10 |
1.7 |
ml/min |
0.2 |
0.63 |
urine creatinine analysis |
0.0 |
0 |
plasma creatinine analysis |
|
|
67283 |
151 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
glomerular filtration trait |
female |
87 days-120 days |
2 |
1.65 |
ml/min |
0.23 |
0.32 |
urine creatinine analysis |
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
51804 |
481 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
glomerular filtration trait |
female |
80 days-99 days |
15 |
1.13 |
ml/min |
0.14 |
0.55 |
urine creatinine analysis |
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52187 |
482 |
BN/NHsdMcwi |
urine creatinine excretion rate |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine creatinine amount |
female |
89 days-92 days |
23 |
0.0 |
mg/d |
0.0 |
0.0 |
urine creatinine analysis |
0.0 |
0 |
|
ug/min |
|
69462 |
151 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
glomerular filtration trait |
female |
92 days-94 days |
8 |
1.1 |
ml/min |
0.2 |
0.57 |
urine creatinine analysis |
0.0 |
0 |
|
mg/min |
|
69479 |
151 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
glomerular filtration trait |
male |
80 days-99 days |
8 |
1.74 |
ml/min |
0.15 |
0.44 |
urine creatinine analysis |
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52186 |
482 |
BN/NHsdMcwi |
urine creatinine level |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine creatinine amount |
female |
92 days-94 days |
25 |
56.4 |
mg/dl |
4.95 |
24.75 |
urine creatinine analysis |
0.0 |
0 |
|
|
|
69475 |
151 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
female |
87 days-120 days |
3 |
0.8 |
ml/min |
0.26 |
0.45 |
urine creatinine analysis |
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51064 |
481 |
BN/NHsdMcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
female |
87 days-120 days |
2 |
1.55 |
ml/min |
0.17 |
0.24 |
urine creatinine analysis |
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
51548 |
481 |