Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
PhenoMiner Database Result        View data table  |  Download data table  |  View expanded data table        


Generate Chart For    
    (Chart displayed below)
Rat Strains

{{sample.term}}
Measurement Methods

{{method.term}}
Age

{{ageRange}}
Experimental Conditions

     {{ cond }}

Minimum Value:    Maximum Value:    Sex:


 
Options:  View chart  |  Download data table  |  View expanded data table
# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1Condition 2aCondition 2bCondition 3aCondition 3b
5logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)F344-DccTn(sb-T2/Bart3)2.205Mcwifemale-8.0994controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)63093controlled sodium content diet (4 %) (for 14 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
7logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)F344-DccTn(sb-T2/Bart3)2.205Mcwimale-8.1904controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)63104controlled sodium content diet (4 %) (for 14 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
3maximum contractile force per wet weight of aortaF344-DccTn(sb-T2/Bart3)2.205Mcwifemale1.27g/mgcontrolled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)63162controlled sodium content diet (4 %) (for 14 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
5maximum contractile force per wet weight of aortaF344-DccTn(sb-T2/Bart3)2.205Mcwimale1.298g/mgcontrolled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)63173controlled sodium content diet (4 %) (for 14 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
5acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselF344-DccTn(sb-T2/Bart3)2.205Mcwifemale49.4%controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)62625controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
7acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselF344-DccTn(sb-T2/Bart3)2.205Mcwimale61.7143%controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)62634controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
5concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)F344-DccTn(sb-T2/Bart3)2.205Mcwifemale0.0101umol/lcontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)62770controlled sodium content diet (4 %) (for 14 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
7concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)F344-DccTn(sb-T2/Bart3)2.205Mcwimale0.0089umol/lcontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)62781controlled sodium content diet (4 %) (for 14 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)F344-DccTn(sb-T2/Bart3)2.205Mcwifemale-6.539controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)62848controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
7logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)F344-DccTn(sb-T2/Bart3)2.205Mcwimale-6.8783controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)62857controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
5concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)F344-DccTn(sb-T2/Bart3)2.205Mcwifemale3.068E-7molecontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)63025controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
7concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)F344-DccTn(sb-T2/Bart3)2.205Mcwimale13.2059E-7molecontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)63034controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)