F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.44 |
ng/ml |
0.03 |
0.07 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
67447 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) and testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
female |
0 days
| 5 |
5.0 |
pg/ml |
0.36 |
0.81 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67456 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
male |
0 days
| 5 |
12.4 |
pg/ml |
1.12 |
2.51 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
67436 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
0.85 |
ng/ml |
0.03 |
0.07 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67443 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.4 |
ng/ml |
0.01 |
0.02 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67451 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
female |
0 days
| 5 |
25.2 |
pg/ml |
1.88 |
4.21 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
67448 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
male |
0 days
| 5 |
8.4 |
pg/ml |
0.9 |
2.01 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67440 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
orchiectomy then 17 beta-estradiol (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) and 17 beta-estradiol (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
male |
0 days
| 5 |
25.7 |
pg/ml |
2.33 |
5.2 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67444 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
ovariectomy then testosterone (3.3 mg/kg) (for 21 days) then N-nitrosodiethylamine (200 mg/kg) (for 56 days) then testosterone (10 mg/kg) (for 35 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
female |
0 days
| 5 |
0.42 |
ng/ml |
0.01 |
0.02 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67455 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
orchiectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
0.95 |
ng/ml |
0.09 |
0.21 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67439 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum testosterone level |
N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood testosterone amount |
male |
0 days
| 5 |
2.0 |
ng/ml |
0.22 |
0.5 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
|
67435 |
655 |
F344.BN-(D16Mit5-D16Rat75) |
serum estradiol level |
ovariectomy then N-nitrosodiethylamine (200 mg/kg) (for 56 days) |
De Miglio MR, et al., Cancer Res. 2006 Nov 1;66(21):10384-90. |
blood estradiol amount |
female |
0 days
| 5 |
13.5 |
pg/ml |
1.65 |
3.7 |
immunoassay |
0.0 |
N-nitrosodiethylamine injection at 200mg/kg |
56 |
days |
intraperitoneal |
67452 |
655 |