FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
12.61 |
ng/ml/h |
1.89 |
4.23 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51002 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
6.62 |
ng/ml/h |
1.19 |
2.66 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51008 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
7 |
4.42 |
ng/ml/h |
0.57 |
1.51 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51009 |
481 |
SS-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
14 |
2.21 |
ng/ml/h |
0.35 |
1.3 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51010 |
481 |
SS-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
9 |
1.9 |
ng/ml/h |
0.26 |
0.78 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51012 |
481 |
Hsd:SD |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
11 |
0.32 |
mg/dl |
0.03 |
0.11 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
51277 |
481 |
SS-Chr 9BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
12 |
0.3 |
mg/dl |
0.01 |
0.04 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51314 |
481 |
SS-Chr 20BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
10 |
0.35 |
mg/dl |
0.01 |
0.03 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51319 |
481 |
GH/OmrMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
3 |
0.28 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51176 |
481 |
FHH/EurMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
9 |
0.29 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51178 |
481 |
GH/OmrMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
8 |
0.31 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51182 |
481 |
SS-Chr 18BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
2 |
0.37 |
mg/dl |
0.07 |
0.09 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51537 |
481 |
WKY/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
6.96 |
ng/ml/h |
0.75 |
2.12 |
radioimmunoassay |
|
0 |
|
51957 |
481 |
F344/DuCrl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
5 |
0.29 |
mg/dl |
0.02 |
0.05 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
51985 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
13.14 |
ng/ml/h |
1.17 |
2.86 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50567 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
3.3 |
ng/ml/h |
0.43 |
0.97 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50568 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
6 |
2.26 |
ng/ml/h |
0.6 |
1.47 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50570 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
15 |
2.88 |
ng/ml/h |
0.5 |
1.95 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50388 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
3 |
7.09 |
ng/ml/h |
3.05 |
5.29 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50392 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
7 |
2.5 |
ng/ml/h |
0.55 |
1.46 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50387 |
481 |
F344/DuCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
8 |
10.84 |
ng/ml/h |
1.35 |
3.83 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
50416 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
2 |
1.29 |
ng/ml/h |
0.49 |
0.69 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50569 |
481 |
LEW/Crl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
4 |
4.31 |
ng/ml/h |
1.53 |
3.06 |
radioimmunoassay |
|
0 |
|
51959 |
481 |
Crl:CD(SD) |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
6 |
0.32 |
mg/dl |
0.02 |
0.05 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
51984 |
481 |
SS/JrHsdMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
4 |
0.35 |
mg/dl |
0.02 |
0.03 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51534 |
481 |
GH/OmrMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
10 |
0.36 |
mg/dl |
0.02 |
0.06 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51312 |
481 |
GH/OmrMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
8 |
0.31 |
mg/dl |
0.02 |
0.06 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51316 |
481 |
SS/JrHsdMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
15 |
0.39 |
mg/dl |
0.06 |
0.21 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51172 |
481 |
BN/NHsdMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
2 |
0.26 |
mg/dl |
0.06 |
0.08 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51179 |
481 |
SS/JrHsdMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
8 |
0.33 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51180 |
481 |
Hsd:SD |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
6.46 |
ng/ml/h |
0.58 |
1.64 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
50895 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
11.87 |
ng/ml/h |
0.85 |
2.08 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50389 |
481 |
LEW/Crl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.32 |
mg/dl |
0.02 |
0.05 |
radioimmunoassay |
|
0 |
|
50410 |
481 |
Hsd:SD |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
12 |
8.82 |
ng/ml/h |
1.04 |
3.62 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
50896 |
481 |
FHH/EurMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
6 |
0.27 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51535 |
481 |
SS/JrHsdMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
12 |
0.31 |
mg/dl |
0.01 |
0.04 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51310 |
481 |
BN/NHsdMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
3 |
0.29 |
mg/dl |
0.0 |
0.01 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51321 |
481 |
Crl:CD(SD) |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
3 |
0.33 |
mg/dl |
0.02 |
0.03 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
51986 |
481 |
SS-Chr 18BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
5 |
0.28 |
mg/dl |
0.06 |
0.14 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51533 |
481 |
SS-Chr 16BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.35 |
mg/dl |
0.01 |
0.03 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51536 |
481 |
SS-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
11 |
3.37 |
ng/ml/h |
0.66 |
2.2 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51004 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
9 |
3.39 |
ng/ml/h |
0.88 |
2.65 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51005 |
481 |
SS-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
11 |
0.91 |
ng/ml/h |
0.18 |
0.59 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51007 |
481 |
SS-Chr 20BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
11 |
0.32 |
mg/dl |
0.02 |
0.06 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51311 |
481 |
BN/NHsdMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
3 |
0.3 |
mg/dl |
0.02 |
0.04 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51322 |
481 |
SS-Chr 16BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.37 |
mg/dl |
0.02 |
0.05 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51174 |
481 |
SHR/NCrl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
7 |
0.29 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51175 |
481 |
SHR/NCrl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
5 |
0.32 |
mg/dl |
0.01 |
0.01 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51181 |
481 |
LEW/Crl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
4.91 |
ng/ml/h |
0.65 |
1.44 |
radioimmunoassay |
|
0 |
|
51958 |
481 |
WKY/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
6.9 |
ng/ml/h |
2.37 |
5.82 |
radioimmunoassay |
|
0 |
|
51960 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
2.8 |
ng/ml/h |
0.87 |
1.94 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50565 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
2 |
1.95 |
ng/ml/h |
0.95 |
1.34 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50566 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
7 |
10.95 |
ng/ml/h |
1.24 |
3.28 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50391 |
481 |
WKY/NCrl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
9 |
0.4 |
mg/dl |
0.02 |
0.06 |
radioimmunoassay |
|
0 |
|
50409 |
481 |
WKY/NCrl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.42 |
mg/dl |
0.03 |
0.07 |
radioimmunoassay |
|
0 |
|
50412 |
481 |
Crl:CD(SD) |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
2 |
5.07 |
ng/ml/h |
0.24 |
0.33 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
50415 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
5.67 |
ng/ml/h |
1.28 |
2.87 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50390 |
481 |
F344/DuCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
7 |
15.17 |
ng/ml/h |
1.06 |
2.81 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
50414 |
481 |
SHR/NCrl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
5 |
0.28 |
mg/dl |
0.01 |
0.03 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51315 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
12 |
1.15 |
ng/ml/h |
0.27 |
0.94 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51003 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
3.33 |
ng/ml/h |
0.45 |
1.11 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51011 |
481 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
1 |
8.99 |
ng/ml/h |
|
|
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51014 |
481 |
SS-Chr 9BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
13 |
0.32 |
mg/dl |
0.01 |
0.03 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51317 |
481 |
FHH/EurMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
7 |
0.28 |
mg/dl |
0.01 |
0.03 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51173 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
9 |
11.85 |
ng/ml/h |
0.69 |
2.08 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50394 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
9 |
3.86 |
ng/ml/h |
0.51 |
1.54 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50395 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
11.16 |
ng/ml/h |
0.5 |
1.41 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50397 |
481 |
Crl:CD(SD) |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
5.64 |
ng/ml/h |
1.41 |
3.16 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
50413 |
481 |
SHR/NCrl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.29 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51318 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
3.34 |
ng/ml/h |
0.14 |
0.39 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50393 |
481 |
LEW/Crl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
4 |
0.32 |
mg/dl |
0.01 |
0.03 |
radioimmunoassay |
|
0 |
|
50411 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
3 |
1.67 |
ng/ml/h |
0.55 |
0.96 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51006 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
4 |
7.2 |
ng/ml/h |
1.34 |
2.68 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51013 |
481 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
3 |
7.64 |
ng/ml/h |
1.68 |
2.91 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51015 |
481 |
SS-Chr 18BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
7 |
0.35 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51171 |
481 |
SS-Chr 16BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
7 |
0.35 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51177 |
481 |
Hsd:SD |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
13 |
0.34 |
mg/dl |
0.01 |
0.04 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
51278 |
481 |
FHH/EurMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.25 |
mg/dl |
0.01 |
0.03 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51309 |
481 |
FHH/EurMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
4 |
0.25 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51320 |
481 |
FHH/EurMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
4 |
0.28 |
mg/dl |
0.02 |
0.04 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51539 |
481 |
F344/DuCrl |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
8 |
0.25 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
51987 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
4 |
12.93 |
ng/ml/h |
1.15 |
2.3 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50571 |
481 |
SS-Chr 16BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
6 |
0.3 |
mg/dl |
0.06 |
0.15 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51538 |
481 |
SS-Chr 18BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.29 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51313 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
9.13 |
ng/ml/h |
0.66 |
1.87 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50396 |
481 |