SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
13 |
0.43 |
ng/ml/h |
0.08 |
0.29 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51833 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
0.65 |
ng/ml/h |
0.25 |
0.6 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51841 |
481 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
3 |
2.06 |
ng/ml/h |
0.69 |
1.19 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51844 |
481 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
1.48 |
ng/ml/h |
0.33 |
0.74 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51845 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
12.61 |
ng/ml/h |
1.89 |
4.23 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51002 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
6.62 |
ng/ml/h |
1.19 |
2.66 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51008 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
7 |
4.42 |
ng/ml/h |
0.57 |
1.51 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51009 |
481 |
SS-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
14 |
2.21 |
ng/ml/h |
0.35 |
1.3 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51010 |
481 |
SS-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
9 |
1.9 |
ng/ml/h |
0.26 |
0.78 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51012 |
481 |
WKY/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
9 |
0.76 |
ng/ml/h |
0.14 |
0.41 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
|
50712 |
481 |
LEW/Crl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
4 |
1.36 |
ng/ml/h |
0.42 |
0.83 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
|
50714 |
481 |
FHH-Chr 15BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
9 |
2.92 |
ng/ml/h |
0.71 |
2.13 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52879 |
482 |
FHH-Chr 5BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
5 |
2.6 |
ng/ml/h |
0.56 |
1.25 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52884 |
482 |
FHH-Chr 2BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
5 |
0.4 |
ng/ml/h |
0.07 |
0.16 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52885 |
482 |
FHH-Chr 6BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
9 |
2.67 |
ng/ml/h |
0.6 |
1.81 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52887 |
482 |
FHH-Chr 19BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
4.98 |
ng/ml/h |
0.69 |
1.82 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52888 |
482 |
FHH-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
8 |
10.07 |
ng/ml/h |
1.37 |
3.87 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52898 |
482 |
FHH-Chr 14BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
2.19 |
ng/ml/h |
0.69 |
1.83 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52902 |
482 |
FHH-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
6.16 |
ng/ml/h |
1.63 |
4.32 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52906 |
482 |
FHH-Chr 17BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
11 |
4.02 |
ng/ml/h |
0.58 |
1.93 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52910 |
482 |
FHH-Chr 11BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
5 |
5.01 |
ng/ml/h |
2.7 |
6.04 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52914 |
482 |
FHH-Chr 7BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
1.89 |
ng/ml/h |
0.44 |
1.17 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52916 |
482 |
FHH-Chr 10BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
4 |
1.23 |
ng/ml/h |
0.39 |
0.78 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52917 |
482 |
FHH-Chr 7BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
8 |
1.15 |
ng/ml/h |
0.48 |
1.35 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52922 |
482 |
LE/BluGill |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
6 |
4.74 |
ng/ml/h |
1.34 |
3.27 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
52579 |
482 |
WKY/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
6.96 |
ng/ml/h |
0.75 |
2.12 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
|
51957 |
481 |
SS-Chr 10BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
10 |
0.93 |
ng/ml/h |
0.12 |
0.39 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52435 |
482 |
SS-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
8 |
1.44 |
ng/ml/h |
0.35 |
0.98 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52442 |
482 |
SS-Chr 7BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
9 |
0.51 |
ng/ml/h |
0.12 |
0.37 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52446 |
482 |
SS-Chr 7BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
11 |
1.31 |
ng/ml/h |
0.26 |
0.87 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52449 |
482 |
SS-Chr 15BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
3 |
1.73 |
ng/ml/h |
0.2 |
0.35 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52454 |
482 |
SS-Chr 13BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
17 |
1.13 |
ng/ml/h |
0.29 |
1.2 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52457 |
482 |
SS-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
0.42 |
ng/ml/h |
0.09 |
0.25 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52459 |
482 |
SS-Chr 1BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
14 |
0.67 |
ng/ml/h |
0.2 |
0.76 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52469 |
482 |
SS-Chr 12BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
0.29 |
ng/ml/h |
0.05 |
0.14 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52474 |
482 |
SS.BN-(D8Rat163-D8Rat81)/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
18 |
0.66 |
ng/ml/h |
0.14 |
0.58 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52478 |
482 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
13.14 |
ng/ml/h |
1.17 |
2.86 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50567 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
3.3 |
ng/ml/h |
0.43 |
0.97 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50568 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
6 |
2.26 |
ng/ml/h |
0.6 |
1.47 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50570 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
3 |
0.64 |
ng/ml/h |
0.27 |
0.47 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50536 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
9.02 |
ng/ml/h |
1.47 |
3.59 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50537 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
15 |
2.88 |
ng/ml/h |
0.5 |
1.95 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50388 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
3 |
7.09 |
ng/ml/h |
3.05 |
5.29 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50392 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
14 |
0.93 |
ng/ml/h |
0.15 |
0.56 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50456 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
7 |
0.9 |
ng/ml/h |
0.26 |
0.68 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50459 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
3 |
1.99 |
ng/ml/h |
0.5 |
0.87 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50460 |
481 |
Hsd:SD |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
8 |
5.34 |
ng/ml/h |
0.79 |
2.24 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
51621 |
481 |
GK/MolTac |
plasma renin activity level |
control condition |
Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
renin activity |
male |
112 days
| 8 |
4.8 |
ng/ml/h |
1.9 |
5.37 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
102947 |
2783 |
SHR/NCrlCrlj |
plasma renin activity level |
unilateral nephrectomy (for 42 days) then controlled delapril content drinking water (30 mg/kg/d) (for 28 days) |
Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. |
renin activity |
male |
126 days
| 9 |
5.1 |
ng/ml/h |
0.5 |
1.5 |
|
radioimmunoassay |
0.0 |
unx |
42 |
days |
|
|
101264 |
2583 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
7 |
2.5 |
ng/ml/h |
0.55 |
1.46 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50387 |
481 |
F344/DuCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
8 |
10.84 |
ng/ml/h |
1.35 |
3.83 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
50416 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
0.7 |
ng/ml/h |
0.15 |
0.42 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50455 |
481 |
FHH-Chr 1BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
9 |
3.7 |
ng/ml/h |
0.8 |
2.4 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52924 |
482 |
SS-Chr 6BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
6 |
3.55 |
ng/ml/h |
1.2 |
2.94 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52438 |
482 |
Crl:WI |
plasma renin activity level |
control condition |
Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
renin activity |
male |
112 days
| 10 |
2.8 |
ng/ml/h |
0.7 |
2.21 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
102946 |
2783 |
SD |
plasma renin activity level |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
renin activity |
male |
0 days
| 6 |
3.1 |
ng/ml/h |
0.29 |
0.7 |
|
radioimmunoassay |
0.0 |
sham unx |
13 |
days |
|
|
101563 |
2602 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
2 |
1.29 |
ng/ml/h |
0.49 |
0.69 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50569 |
481 |
LEW/Crl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
4 |
4.31 |
ng/ml/h |
1.53 |
3.06 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
|
51959 |
481 |
SS.BN-(D12Arb13-D12Rat79)/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
8 |
1.01 |
ng/ml/h |
0.34 |
0.95 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52440 |
482 |
SS-Chr 17BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
8 |
0.36 |
ng/ml/h |
0.08 |
0.22 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52445 |
482 |
SS-Chr 5BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
0.44 |
ng/ml/h |
0.08 |
0.2 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52448 |
482 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
8 |
0.91 |
ng/ml/h |
0.2 |
0.58 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52452 |
482 |
SS-Chr 15BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
0.28 |
ng/ml/h |
0.02 |
0.05 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52453 |
482 |
SS-Chr YBN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
12 |
0.26 |
ng/ml/h |
0.02 |
0.06 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52463 |
482 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
55 |
0.68 |
ng/ml/h |
0.12 |
0.9 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52465 |
482 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
9 |
1.17 |
ng/ml/h |
0.22 |
0.66 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52471 |
482 |
SS-Chr 4BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
1.23 |
ng/ml/h |
0.24 |
0.64 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52476 |
482 |
FHH-Chr 8BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
2 |
3.48 |
ng/ml/h |
1.03 |
1.46 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52880 |
482 |
FHH-Chr 3BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
1 |
1.17 |
ng/ml/h |
|
|
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52883 |
482 |
FHH-Chr 14BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
5 |
4.35 |
ng/ml/h |
1.32 |
2.96 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52886 |
482 |
FHH-Chr 6BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
6 |
3.2 |
ng/ml/h |
0.43 |
1.06 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52889 |
482 |
FHH-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
1 |
1.4 |
ng/ml/h |
|
|
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52893 |
482 |
FHH-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
4.81 |
ng/ml/h |
0.78 |
2.07 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52895 |
482 |
FHH-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
6 |
3.02 |
ng/ml/h |
0.98 |
2.41 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52896 |
482 |
FHH-Chr 12BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
10 |
1.71 |
ng/ml/h |
0.17 |
0.52 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52897 |
482 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
38 |
2.57 |
ng/ml/h |
0.36 |
2.21 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52899 |
482 |
FHH-Chr XBN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
6 |
2.25 |
ng/ml/h |
0.51 |
1.25 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52913 |
482 |
FHH-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
4 |
2.48 |
ng/ml/h |
0.69 |
1.38 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52921 |
482 |
FHH-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
4.85 |
ng/ml/h |
1.02 |
2.7 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52923 |
482 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
3 |
0.84 |
ng/ml/h |
0.08 |
0.14 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51836 |
481 |
SS-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
10 |
0.58 |
ng/ml/h |
0.14 |
0.43 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51842 |
481 |
F344/DuCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
8 |
2.16 |
ng/ml/h |
0.24 |
0.68 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
51606 |
481 |
Hsd:SD |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
6.46 |
ng/ml/h |
0.58 |
1.64 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
50895 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
11.87 |
ng/ml/h |
0.85 |
2.08 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50389 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
7 |
0.83 |
ng/ml/h |
0.23 |
0.6 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50464 |
481 |
WKY |
plasma renin activity level |
puromycin aminonucleoside (50 mg/kg) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
renin activity |
male |
0 days
| 12 |
7.4 |
ng/ml/h |
0.8 |
2.77 |
|
radioimmunoassay |
0.0 |
PA IV 50mg/kg |
0 |
|
|
|
100425 |
2479 |
WKY |
plasma renin activity level |
controlled enalapril content drinking water (50 mg/l) (between 63 and 77 days) then puromycin aminonucleoside (50 mg/kg) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
renin activity |
male |
0 days
| 12 |
206.8 |
ng/ml/h |
20.7 |
71.71 |
|
radioimmunoassay |
0.0 |
PA IV 50mg/kg |
0 |
|
|
|
100426 |
2479 |
WKY |
plasma renin activity level |
puromycin aminonucleoside (50 mg/kg) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
renin activity |
male |
0 days
| 11 |
8.8 |
ng/ml/h |
1.0 |
3.32 |
|
radioimmunoassay |
0.0 |
PA IV 50mg/kg |
23 |
days |
|
|
100422 |
2479 |
SHR/N-cp |
plasma renin activity level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
renin activity |
male |
168 days-196 days |
8 |
11.0 |
ng/ml/h |
2.0 |
5.66 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
101532 |
2601 |
SHR/N-cp |
plasma renin activity level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
renin activity |
male |
168 days-196 days |
8 |
52.0 |
ng/ml/h |
8.0 |
22.63 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
101533 |
2601 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
1.57 |
ng/ml/h |
0.07 |
0.16 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50538 |
481 |
Hsd:SD |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
12 |
8.82 |
ng/ml/h |
1.04 |
3.62 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
50896 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
1.22 |
ng/ml/h |
0.11 |
0.31 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50461 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
7 |
1.67 |
ng/ml/h |
0.24 |
0.62 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50463 |
481 |
Crl:CD(SD) |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
6 |
1.14 |
ng/ml/h |
0.3 |
0.74 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
51603 |
481 |
SS.BN-(D12Arb13-D12Rat79)/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
9 |
0.49 |
ng/ml/h |
0.16 |
0.49 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52436 |
482 |
WKY |
plasma renin activity level |
0.9% sodium chloride solution (3 ml) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
renin activity |
male |
0 days
| 11 |
11.9 |
ng/ml/h |
1.0 |
3.32 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
100424 |
2479 |
F344/DuCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
7 |
3.27 |
ng/ml/h |
0.47 |
1.25 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
51604 |
481 |
SS-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
11 |
3.37 |
ng/ml/h |
0.66 |
2.2 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51004 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
9 |
3.39 |
ng/ml/h |
0.88 |
2.65 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51005 |
481 |
SS-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
11 |
0.91 |
ng/ml/h |
0.18 |
0.59 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51007 |
481 |
WKY/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
3.33 |
ng/ml/h |
1.41 |
3.46 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
|
50715 |
481 |
SS-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
9 |
1.75 |
ng/ml/h |
0.31 |
0.92 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51834 |
481 |
LEW/Crl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
4.91 |
ng/ml/h |
0.65 |
1.44 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
|
51958 |
481 |
WKY/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
6.9 |
ng/ml/h |
2.37 |
5.82 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
|
51960 |
481 |
FHH-Chr 12BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
7.44 |
ng/ml/h |
1.44 |
3.8 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52878 |
482 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
14 |
6.0 |
ng/ml/h |
0.7 |
2.62 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52881 |
482 |
FHH-Chr 5BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
1.16 |
ng/ml/h |
0.33 |
0.88 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52890 |
482 |
FHH-Chr 8BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
2 |
2.11 |
ng/ml/h |
0.7 |
0.98 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52891 |
482 |
FHH-Chr 13BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
8.07 |
ng/ml/h |
0.72 |
1.91 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52892 |
482 |
FHH-Chr 13BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
10 |
4.42 |
ng/ml/h |
0.78 |
2.47 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52894 |
482 |
FHH-Chr YBN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
4 |
2.47 |
ng/ml/h |
0.64 |
1.27 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52903 |
482 |
FHH-Chr 10BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
4.33 |
ng/ml/h |
0.93 |
2.46 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52905 |
482 |
FHH-Chr 4BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
4 |
4.38 |
ng/ml/h |
1.19 |
2.38 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52908 |
482 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
1.61 |
ng/ml/h |
0.88 |
2.33 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52919 |
482 |
FHH-Chr XBN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
5 |
4.63 |
ng/ml/h |
0.97 |
2.16 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52920 |
482 |
SS-Chr 14BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
9 |
0.87 |
ng/ml/h |
0.09 |
0.27 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52437 |
482 |
SS-Chr 6BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
8 |
1.2 |
ng/ml/h |
0.42 |
1.18 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52443 |
482 |
SS-Chr 10BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
8 |
3.82 |
ng/ml/h |
0.85 |
2.41 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52444 |
482 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
9 |
0.41 |
ng/ml/h |
0.15 |
0.44 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52456 |
482 |
SS-Chr 3BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
5 |
2.16 |
ng/ml/h |
0.15 |
0.33 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52458 |
482 |
SS-Chr 11BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
14 |
1.11 |
ng/ml/h |
0.26 |
0.96 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52460 |
482 |
SS-Chr 1BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
16 |
0.49 |
ng/ml/h |
0.07 |
0.29 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52466 |
482 |
SS-Chr 4BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
0.5 |
ng/ml/h |
0.14 |
0.36 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52470 |
482 |
SS-Chr 12BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
5 |
0.88 |
ng/ml/h |
0.15 |
0.33 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52479 |
482 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
8 |
1.01 |
ng/ml/h |
0.15 |
0.43 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52480 |
482 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
15 |
4.4 |
ng/ml/h |
1.26 |
4.87 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52481 |
482 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
1 |
0.67 |
ng/ml/h |
|
|
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50539 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
6 |
7.97 |
ng/ml/h |
1.02 |
2.5 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50541 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
2.8 |
ng/ml/h |
0.87 |
1.94 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50565 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
2 |
1.95 |
ng/ml/h |
0.95 |
1.34 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50566 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
7 |
10.95 |
ng/ml/h |
1.24 |
3.28 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50391 |
481 |
Crl:CD(SD) |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
2 |
5.07 |
ng/ml/h |
0.24 |
0.33 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
50415 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
9.06 |
ng/ml/h |
1.26 |
3.08 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50457 |
481 |
SD |
plasma renin activity level |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
renin activity |
male |
0 days
| 11 |
4.3 |
ng/ml/h |
0.63 |
2.08 |
|
radioimmunoassay |
0.0 |
unx |
13 |
days |
- |
|
101564 |
2602 |
SHR/NCrlCrlj |
plasma renin activity level |
unilateral nephrectomy (for 42 days) |
Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. |
renin activity |
male |
126 days
| 5 |
1.3 |
ng/ml/h |
0.2 |
0.45 |
|
radioimmunoassay |
0.0 |
unx |
42 |
days |
|
|
101262 |
2583 |
SS/NEisSlc |
plasma renin activity level |
controlled sodium content diet (8 %) (for 42 days) then 0.9% sodium chloride solution (0.3 ml) (for 42 days) |
Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. |
renin activity |
male |
91 days
| 12 |
3.6 |
ng/ml/h |
1.32 |
4.57 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
100687 |
2519 |
SS/NEisSlc |
plasma renin activity level |
controlled sodium content diet (8 %) (for 42 days) then cilazapril (10 mg/kg/d) (for 42 days) |
Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. |
renin activity |
male |
91 days
| 6 |
5.72 |
ng/ml/h |
1.36 |
3.33 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
100690 |
2519 |
WKY |
plasma renin activity level |
controlled enalapril content drinking water (50 mg/l) (for 30 days) then puromycin aminonucleoside (50 mg/kg) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
renin activity |
male |
0 days
| 10 |
100.3 |
ng/ml/h |
18.6 |
58.82 |
|
radioimmunoassay |
0.0 |
PA IV 50mg/kg |
23 |
days |
|
|
100423 |
2479 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
6 |
0.77 |
ng/ml/h |
0.33 |
0.8 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50540 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
5.67 |
ng/ml/h |
1.28 |
2.87 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50390 |
481 |
F344/DuCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
7 |
15.17 |
ng/ml/h |
1.06 |
2.81 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
50414 |
481 |
LE/BluGill |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
8 |
3.46 |
ng/ml/h |
1.44 |
4.09 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
52578 |
482 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
12 |
1.15 |
ng/ml/h |
0.27 |
0.94 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51003 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
3.33 |
ng/ml/h |
0.45 |
1.11 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51011 |
481 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
1 |
8.99 |
ng/ml/h |
|
|
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51014 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
8.51 |
ng/ml/h |
2.42 |
5.42 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51832 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
9 |
1.07 |
ng/ml/h |
0.29 |
0.86 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51835 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
6 |
1.23 |
ng/ml/h |
0.27 |
0.66 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51838 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
1.69 |
ng/ml/h |
0.33 |
0.94 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51839 |
481 |
SS-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
8 |
0.29 |
ng/ml/h |
0.04 |
0.13 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52439 |
482 |
SS-Chr 5BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
6 |
0.68 |
ng/ml/h |
0.33 |
0.8 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52450 |
482 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
9 |
0.75 |
ng/ml/h |
0.15 |
0.45 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52464 |
482 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
8 |
1.04 |
ng/ml/h |
0.18 |
0.51 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52468 |
482 |
SS.BN-(D8Rat163-D8Rat81)/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
10 |
1.79 |
ng/ml/h |
0.42 |
1.31 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52472 |
482 |
SS-Chr 2BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
10 |
0.99 |
ng/ml/h |
0.13 |
0.43 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52477 |
482 |
SS-Chr XBN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
4 |
1.04 |
ng/ml/h |
0.33 |
0.65 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52482 |
482 |
FHH-Chr 15BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
2.41 |
ng/ml/h |
0.58 |
1.53 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52900 |
482 |
FHH-Chr 17BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
0.68 |
ng/ml/h |
0.16 |
0.42 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52909 |
482 |
FHH-Chr 11BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
3 |
1.02 |
ng/ml/h |
0.4 |
0.69 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52912 |
482 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
8 |
0.26 |
ng/ml/h |
0.03 |
0.08 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52918 |
482 |
Hsd:SD |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
1.65 |
ng/ml/h |
0.44 |
0.98 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan |
51620 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
9 |
11.85 |
ng/ml/h |
0.69 |
2.08 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50394 |
481 |
SS/JrHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
9 |
3.86 |
ng/ml/h |
0.51 |
1.54 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50395 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
11.16 |
ng/ml/h |
0.5 |
1.41 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50397 |
481 |
Crl:CD(SD) |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
5.64 |
ng/ml/h |
1.41 |
3.16 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
50413 |
481 |
SHR/NCrlCrlj |
plasma renin activity level |
unilateral nephrectomy (for 42 days) then controlled candesartan content drinking water (1 mg/kg/d) (for 28 days) |
Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. |
renin activity |
male |
126 days
| 8 |
9.8 |
ng/ml/h |
1.7 |
4.81 |
|
radioimmunoassay |
0.0 |
unx |
42 |
days |
|
|
101263 |
2583 |
SHR/NCrlCrlj |
plasma renin activity level |
unilateral nephrectomy (for 42 days) then controlled hydralazine content drinking water (15 mg/kg/d) (for 28 days) |
Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. |
renin activity |
male |
126 days
| 5 |
5.5 |
ng/ml/h |
1.7 |
3.8 |
|
radioimmunoassay |
0.0 |
unx |
42 |
days |
|
|
101265 |
2583 |
WKY |
plasma renin activity level |
0.9% sodium chloride solution (3 ml) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
renin activity |
male |
0 days
| 10 |
10.7 |
ng/ml/h |
1.7 |
5.38 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
100421 |
2479 |
SR/NEisSlc |
plasma renin activity level |
controlled sodium content diet (0.3 %) (for 91 days) |
Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. |
renin activity |
male |
91 days
| 6 |
3.23 |
ng/ml/h |
0.45 |
1.11 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
100689 |
2519 |
MW |
plasma renin activity level |
sham surgical control condition (for 28 days) |
Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. |
renin activity |
male |
0 days
| 7 |
9.1 |
ng/ml/h |
0.5 |
1.32 |
|
radioimmunoassay |
0.0 |
sham surgery |
28 |
days |
|
|
101043 |
2561 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
3.34 |
ng/ml/h |
0.14 |
0.39 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50393 |
481 |
SS-Chr 16BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
2.08 |
ng/ml/h |
0.23 |
0.56 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50458 |
481 |
SS/NEisSlc |
plasma renin activity level |
controlled sodium content diet (8 %) (for 42 days) then candesartan (1 mg/kg/d) (for 42 days) |
Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. |
renin activity |
male |
91 days
| 6 |
8.35 |
ng/ml/h |
2.34 |
5.73 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
100691 |
2519 |
MW |
plasma renin activity level |
nephrectomy (for 28 days) then reserpine (5 mg/l) (for 21 days) and hydralazine (80 mg/l) (for 21 days) and controlled hydralazine content drinking water (25 mg/l) (for 21 days) |
Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. |
renin activity |
male |
0 days
| 7 |
21.9 |
ng/ml/h |
2.5 |
6.61 |
|
radioimmunoassay |
0.0 |
5/6 nephrectomy |
28 |
days |
|
|
101046 |
2561 |
SS-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
12 |
0.38 |
ng/ml/h |
0.04 |
0.14 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51837 |
481 |
SS-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
14 |
1.08 |
ng/ml/h |
0.12 |
0.45 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51840 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
4.01 |
ng/ml/h |
1.09 |
2.43 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51843 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
3 |
1.67 |
ng/ml/h |
0.55 |
0.96 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51006 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
4 |
7.2 |
ng/ml/h |
1.34 |
2.68 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51013 |
481 |
BN/NHsdMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
3 |
7.64 |
ng/ml/h |
1.68 |
2.91 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Teklad |
51015 |
481 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
4 |
12.93 |
ng/ml/h |
1.15 |
2.3 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50571 |
481 |
SS-Chr 17BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
6 |
0.92 |
ng/ml/h |
0.24 |
0.6 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52447 |
482 |
SS-Chr 20BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
8 |
1.66 |
ng/ml/h |
0.38 |
1.07 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52451 |
482 |
SS-Chr 3BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
8 |
0.42 |
ng/ml/h |
0.07 |
0.2 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52455 |
482 |
SS-Chr 13BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
17 |
0.43 |
ng/ml/h |
0.09 |
0.35 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52461 |
482 |
SS-Chr 11BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
14 |
0.34 |
ng/ml/h |
0.09 |
0.33 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52462 |
482 |
SS-Chr XBN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
3 |
1.82 |
ng/ml/h |
0.72 |
1.25 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52467 |
482 |
SS-Chr 19BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
4 |
0.27 |
ng/ml/h |
0.04 |
0.08 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52473 |
482 |
SS-Chr 19BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
7 |
0.66 |
ng/ml/h |
0.09 |
0.25 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52475 |
482 |
SS-Chr 2BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
9 |
0.58 |
ng/ml/h |
0.1 |
0.29 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52483 |
482 |
FHH-Chr 19BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
2.2 |
ng/ml/h |
0.96 |
2.54 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52882 |
482 |
FHH-Chr 3BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
3 |
1.53 |
ng/ml/h |
1.17 |
2.02 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52901 |
482 |
FHH-Chr 2BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
4 |
1.73 |
ng/ml/h |
0.23 |
0.46 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52904 |
482 |
FHH-Chr 1BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
7 |
3.1 |
ng/ml/h |
0.58 |
1.53 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52907 |
482 |
FHH-Chr 4BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
8 |
11.17 |
ng/ml/h |
2.91 |
8.22 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52911 |
482 |
FHH-Chr 9BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80 days-99 days |
4 |
4.64 |
ng/ml/h |
0.91 |
1.82 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52915 |
482 |
FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
9.0 |
ng/ml/h |
0.76 |
2.15 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50462 |
481 |
GH/OmrMcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
1.93 |
ng/ml/h |
0.26 |
0.74 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50465 |
481 |
SD |
plasma renin activity level |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
renin activity |
male |
0 days
| 5 |
13.3 |
ng/ml/h |
5.5 |
12.3 |
|
radioimmunoassay |
0.0 |
unx |
13 |
days |
|
|
101565 |
2602 |
SD |
plasma renin activity level |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
renin activity |
male |
0 days
| 5 |
5.2 |
ng/ml/h |
2.24 |
5.0 |
|
radioimmunoassay |
0.0 |
unx |
13 |
days |
|
|
101566 |
2602 |
MW |
plasma renin activity level |
nephrectomy (for 28 days) then enalapril (50 mg/l) (for 21 days) |
Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. |
renin activity |
male |
0 days
| 7 |
194.5 |
ng/ml/h |
28.0 |
74.08 |
|
radioimmunoassay |
0.0 |
5/6 nephrectomy |
28 |
days |
|
|
101045 |
2561 |
SHR/N-cp |
plasma renin activity level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
renin activity |
male |
140 days-168 days |
8 |
38.0 |
ng/ml/h |
2.0 |
5.66 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
101534 |
2601 |
LEW/Crl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
6 |
2.17 |
ng/ml/h |
0.86 |
2.11 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
|
50713 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
0.3 |
ng/ml/h |
0.03 |
0.07 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50535 |
481 |
Crl:CD(SD) |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
5 |
1.32 |
ng/ml/h |
0.64 |
1.42 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
51605 |
481 |
SHR/NCrl |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
8 |
9.13 |
ng/ml/h |
0.66 |
1.87 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms and pups used in studies were fed Dyets |
50396 |
481 |
SS-Chr 14BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80 days-99 days |
8 |
0.42 |
ng/ml/h |
0.1 |
0.29 |
Download Values
|
radioimmunoassay |
|
|
0 |
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52441 |
482 |
SS/NEisSlc |
plasma renin activity level |
controlled sodium content diet (0.3 %) (for 91 days) |
Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. |
renin activity |
male |
91 days
| 6 |
2.49 |
ng/ml/h |
0.63 |
1.53 |
|
radioimmunoassay |
0.0 |
|
0 |
|
|
|
100688 |
2519 |
MW |
plasma renin activity level |
nephrectomy (for 28 days) then control condition |
Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. |
renin activity |
male |
0 days
| 7 |
3.8 |
ng/ml/h |
0.7 |
1.85 |
|
radioimmunoassay |
0.0 |
5/6 nephrectomy |
28 |
days |
|
|
101044 |
2561 |