Study ID,Study,Experiment Name,Experiment Notes,Strain Ont ID,Strain,Sex,Age,# of Animals,Sample Notes,Clinical Measurement Ont ID,Phenotype,Formula,Clinical Measurement Notes,Average Type,Value,Units,SEM,SD,Method Ont ID,Method,Method Site,Method Duration,Method Notes,Post Insult Type,Post Insult Time Value,Post Insult Time Unit,Conditions,Record ID,Condition 1,Condition 2,Condition 3 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,61 days to 53 days,0,,CMO:0002035,percent change in mean arterial blood pressure,,% change map,,17,%,1.0,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,blood pressure measured after infusion,,,,sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours),69733,sodium ion solution (800 mmol/l) (for 4 days),air-jet exposure (2 lb/in2) (for 0 hours), 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,61 days to 53 days,0,,CMO:0000533,absolute change in mean arterial blood pressure,,,,23,mmHg,1.0,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,blood pressure measured after infusion,,,,sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours),69729,sodium ion solution (800 mmol/l) (for 4 days),air-jet exposure (2 lb/in2) (for 0 hours), 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,61 days to 53 days,0,,CMO:0000533,absolute change in mean arterial blood pressure,,"1min measurement per 30min, 24 hr average",,13,mmHg,1.0,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,blood pressure measured after infusion,,,,sodium ion solution (800 mmol/l) (for 14 days),68142,sodium ion solution (800 mmol/l) (for 14 days),, 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,51 days to 43 days,0,,CMO:0000533,absolute change in mean arterial blood pressure,,"1min measurement per 30min, 24 hr average",,17,mmHg,2.0,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,blood pressure measured after infusion,,,,sodium ion solution (800 mmol/l) (for 4 days),68138,sodium ion solution (800 mmol/l) (for 4 days),, 830,"Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,59 days to 56 days,16,,CMO:0000009,mean arterial blood pressure,,,,177,mmHg,,,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400.0,,,,,controlled sodium content diet (2 %) (for 21 days),68086,controlled sodium content diet (2 %) (for 21 days),, 563,"Crespo K, et al., J Hypertens. 2011 Mar;29(3):460-5.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,73 days to 66 days,14,,CMO:0000009,mean arterial blood pressure,,,,178,mmHg,4.0,14.9666,MMO:0000070,intra-aortic abdominal radiotelemetry,,0,,,,,controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 49 days),65147,controlled sodium content diet (0.2 %) (for 14 days),controlled sodium content diet (2 %) (between 31 and 49 days), 242,"Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,72 days to 56 days,18,,CMO:0000009,mean arterial blood pressure,,,,170,mmHg,4.0,16.9706,MMO:0000070,intra-aortic abdominal radiotelemetry,,,,,,,controlled sodium content diet (2 %) (between 21 and 37 days),12354,controlled sodium content diet (2 %) (between 21 and 37 days),, 269,"Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,56 days,10,,CMO:0000009,mean arterial blood pressure,,,,175,mmHg,4.0,12.6491,MMO:0000070,intra-aortic abdominal radiotelemetry,aorta,,,,,,controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days),12544,controlled sodium content diet (0.2 %) (for 14 days),controlled sodium content diet (2 %) (for 21 days), 261,"Grondin M, et al., Physiol Genomics 2005 Mar 21;21(1):112-6. Epub 2005 Jan 4.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,92 days to 88 days,19,,CMO:0000009,mean arterial blood pressure,,measure every 2 min for 24 hrs,,169,mmHg,4.0,17.4356,MMO:0000070,intra-aortic abdominal radiotelemetry,,,,,,,controlled sodium content diet (2 %) (between 43 and 47 days),12422,controlled sodium content diet (2 %) (between 43 and 47 days),, 269,"Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,56 days,16,,CMO:0000009,mean arterial blood pressure,,,,184,mmHg,4.0,16.0,MMO:0000070,intra-aortic abdominal radiotelemetry,aorta,,,,,,controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days),12595,controlled sodium content diet (0.2 %) (for 14 days),controlled sodium content diet (2 %) (for 21 days), 328,"Moujahidine M, et al., Mamm Genome 2002 Mar;13(3):153-6.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,71 days to 56 days,11,,CMO:0000009,mean arterial blood pressure,,average of 6 measurements taken every 4 hrs,serial mean,184,mmHg,5.0,16.5831,MMO:0000070,intra-aortic abdominal radiotelemetry,aorta,0,,,,,controlled sodium content diet (2 %) (between 21 and 36 days),13078,controlled sodium content diet (2 %) (between 21 and 36 days),, 305,"Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,79 days to 75 days,5,,CMO:0000009,mean arterial blood pressure,,average of 12 4-hour averages over 48 hours using 5 or 6 rats,serial mean,158,mmHg,1.76,3.9355,MMO:0000070,intra-aortic abdominal radiotelemetry,lower abdominal aorta,172800,"C-40 transmitter (Data Sciences International, St. Paul, MN)",,,,controlled sodium content diet (2 %) (between 35 and 37 days),13035,controlled sodium content diet (2 %) (between 35 and 37 days),, 304,"Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,78 days to 66 days,21,,CMO:0000009,mean arterial blood pressure,,average of 24 hour averages over 12 days,serial mean,177,mmHg,6.0,27.4955,MMO:0000070,intra-aortic abdominal radiotelemetry,abdominal aorta,1036800.0,"telemetry probe model PA-D70, Data Sciences, St. Paul, MN",,,,controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days),12737,controlled sodium content diet (0.2 %) (for 14 days),controlled sodium content diet (2 %) (between 31 and 50 days), 242,"Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,72 days to 56 days,10,,CMO:0000009,mean arterial blood pressure,,,,170,mmHg,5.0,15.8114,MMO:0000070,intra-aortic abdominal radiotelemetry,,,,,,,controlled sodium content diet (2 %) (between 21 and 37 days),12322,controlled sodium content diet (2 %) (between 21 and 37 days),, 611,"Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,80 days to 73 days,8,,CMO:0000009,mean arterial blood pressure,,average of 24 hr,,172,mmHg,5.0,14.1421,MMO:0000070,intra-aortic abdominal radiotelemetry,,10,,,,,controlled sodium content diet (2 %) (between 34 and 38 days),65496,controlled sodium content diet (2 %) (between 34 and 38 days),, 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",heart pumping trait,,RS:0000817,SS/Jr,male,50 days to 43 days,0,,CMO:0000742,percent change in heart rate,,,,10,%,1.0,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,,,,,sodium ion solution (800 mmol/l) (for 14 days),69702,sodium ion solution (800 mmol/l) (for 14 days),, 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",heart pumping trait,,RS:0000817,SS/Jr,male,61 days to 53 days,0,,CMO:0000742,percent change in heart rate,,,,10,%,0.3,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,blood pressure measured after infusion,,,,sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours),69741,sodium ion solution (800 mmol/l) (for 4 days),air-jet exposure (2 lb/in2) (for 0 hours), 611,"Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,80 days to 73 days,8,,CMO:0000292,pulse pressure,,average of 24 hr,,52,mmHg,3.4,9.6167,MMO:0000070,intra-aortic abdominal radiotelemetry,,10,,,,,controlled sodium content diet (2 %) (between 34 and 38 days),65495,controlled sodium content diet (2 %) (between 34 and 38 days),, 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",heart pumping trait,,RS:0000817,SS/Jr,male,50 days to 43 days,0,,CMO:0000534,absolute change in heart rate,,,,54,beats/min,6.0,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,,,,,sodium ion solution (800 mmol/l) (for 14 days),69698,sodium ion solution (800 mmol/l) (for 14 days),, 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",heart pumping trait,,RS:0000817,SS/Jr,male,61 days to 53 days,0,,CMO:0000534,absolute change in heart rate,,,,45,beats/min,3.0,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,blood pressure measured after infusion,,,,sodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours),69737,sodium ion solution (800 mmol/l) (for 4 days),air-jet exposure (2 lb/in2) (for 0 hours), 305,"Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,79 days to 75 days,5,,CMO:0000004,systolic blood pressure,,average of 12 4-hour averages over 48 hours using 5 or 6 rats,serial mean,185,mmHg,1.97,4.4051,MMO:0000070,intra-aortic abdominal radiotelemetry,lower abdominal aorta,172800,"C-40 transmitter (Data Sciences International, St. Paul, MN)",,,,controlled sodium content diet (2 %) (between 35 and 37 days),13026,controlled sodium content diet (2 %) (between 35 and 37 days),, 205,"Saad Y, et al., Hypertension. 2007",arterial blood pressure trait,,RS:0000817,SS/Jr,male,84 days to 81 days,9,,CMO:0000004,systolic blood pressure,,recorded every 5 minutes for 4 days,,213,mmHg,7.47,22.41,MMO:0000070,intra-aortic abdominal radiotelemetry,aorta,345600.0,,,,,controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 42 days),12072,controlled sodium content diet (0.3 %) (for 12 days),controlled sodium content diet (2 %) (for 42 days), 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,149 days to 147 days,1,,CMO:0000004,systolic blood pressure,,,,219.7,mmHg,1.7,1.7,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days),65053,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (for 28 days),controlled sodium content diet (4 %) (between 79 and 80 days) 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,116 days to 114 days,3,,CMO:0000004,systolic blood pressure,,,,219.3,mmHg,4.2,7.2746,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days),65050,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (for 28 days),controlled sodium content diet (4 %) (between 46 and 47 days) 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,109 days to 107 days,3,,CMO:0000004,systolic blood pressure,,,,228.2,mmHg,2.6,4.5033,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days),65047,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (for 28 days),controlled sodium content diet (4 %) (between 39 and 40 days) 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,78 days to 76 days,5,,CMO:0000004,systolic blood pressure,,,,217.9,mmHg,2.1,4.6957,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days),65044,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (for 28 days),controlled sodium content diet (4 %) (between 9 and 10 days) 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,69 days to 67 days,5,,CMO:0000004,systolic blood pressure,,,,181,mmHg,3.6,8.0498,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days),65041,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (between 27 and 28 days), 611,"Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,80 days to 73 days,8,,CMO:0000004,systolic blood pressure,,average of 24 hr,,199,mmHg,5.0,14.1421,MMO:0000070,intra-aortic abdominal radiotelemetry,,10,,,,,controlled sodium content diet (2 %) (between 34 and 38 days),65493,controlled sodium content diet (2 %) (between 34 and 38 days),, 305,"Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,79 days to 75 days,5,,CMO:0000005,diastolic blood pressure,,average of 12 4-hour averages over 48 hours using 5 or 6 rats,serial mean,130,mmHg,1.57,3.5106,MMO:0000070,intra-aortic abdominal radiotelemetry,lower abdominal aorta,172800,"C-40 transmitter (Data Sciences International, St. Paul, MN)",,,,controlled sodium content diet (2 %) (between 35 and 37 days),13031,controlled sodium content diet (2 %) (between 35 and 37 days),, 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,149 days to 147 days,1,,CMO:0000005,diastolic blood pressure,,,,152.5,mmHg,1.7,1.7,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days),65069,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (for 28 days),controlled sodium content diet (4 %) (between 79 and 80 days) 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,116 days to 114 days,3,,CMO:0000005,diastolic blood pressure,,,,158.2,mmHg,3.9,6.755,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days),65066,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (for 28 days),controlled sodium content diet (4 %) (between 46 and 47 days) 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,109 days to 107 days,3,,CMO:0000005,diastolic blood pressure,,,,164.9,mmHg,2.3,3.9837,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days),65063,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (for 28 days),controlled sodium content diet (4 %) (between 39 and 40 days) 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,78 days to 76 days,4,,CMO:0000005,diastolic blood pressure,,,,153,mmHg,1.6,3.2,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days),65060,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (for 28 days),controlled sodium content diet (4 %) (between 9 and 10 days) 283,"Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,69 days to 67 days,5,,CMO:0000005,diastolic blood pressure,,,,125.2,mmHg,3.0,6.7082,MMO:0000070,intra-aortic abdominal radiotelemetry,,86400,,,,,controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days),65057,controlled sodium content diet (0.3 %) (between 10 and 12 days),controlled sodium content diet (2 %) (between 27 and 28 days), 611,"Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,80 days to 73 days,8,,CMO:0000005,diastolic blood pressure,,average of 24 hr,,147,mmHg,5.5,15.5563,MMO:0000070,intra-aortic abdominal radiotelemetry,,10,,,,,controlled sodium content diet (2 %) (between 34 and 38 days),65494,controlled sodium content diet (2 %) (between 34 and 38 days),, 305,"Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.",heart pumping trait,,RS:0000817,SS/Jr,male,79 days to 75 days,5,,CMO:0000002,heart rate,,,,378,beats/min,9.18,20.5271,MMO:0000070,intra-aortic abdominal radiotelemetry,,172800,,,,,controlled sodium content diet (2 %) (for 37 days),64986,controlled sodium content diet (2 %) (for 37 days),, 611,"Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.",heart pumping trait,,RS:0000817,SS/Jr,male,80 days to 73 days,8,,CMO:0000002,heart rate,,diurnal difference,,390,beats/min,4.1,11.5966,MMO:0000070,intra-aortic abdominal radiotelemetry,,10,,,,,controlled sodium content diet (2 %) (between 34 and 38 days),65503,controlled sodium content diet (2 %) (between 34 and 38 days),, 611,"Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.",arterial blood pressure trait,,RS:0000817,SS/Jr,male,80 days to 73 days,8,,CMO:0000607,absolute change in systolic blood pressure,,diurnal difference,,22.6,mmHg,1.05,2.9698,MMO:0000070,intra-aortic abdominal radiotelemetry,,10,,,,,controlled sodium content diet (2 %) (between 34 and 38 days) then controlled exposure to darkness then controlled exposure to ambient light,65497,controlled sodium content diet (2 %) (between 34 and 38 days),controlled exposure to darkness,controlled exposure to ambient light 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",heart pumping trait,,RS:0000817,SS/Jr,male,61 days to 53 days,0,,CMO:0002037,maximum change in heart rate to change in mean arterial blood pressure ratio,,"Maximum slope, bpm/mm Hg",,-1.8,beats/min/mmHg,0.2,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,blood pressure measured after infusion,,,,sodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5~50 ug/min) then sodium nitroprusside (10~100 ug/min) ,69745,sodium ion solution (800 mmol/l) (for 4 days),phenylephrine (5~50 ug/min) ,sodium nitroprusside (10~100 ug/min) 344,"Huang BS, et al., Hypertension. 2007 Apr 9;.",heart pumping trait,,RS:0000817,SS/Jr,male,61 days to 53 days,0,,CMO:0002036,change in heart rate to change in mean arterial blood pressure ratio,,"average slope, bpm/mm Hg",,-1.6,beats/min/mmHg,0.2,,MMO:0000070,intra-aortic abdominal radiotelemetry,,0.0,blood pressure measured after infusion,,,,sodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5~50 ug/min) then sodium nitroprusside (10~100 ug/min) ,69749,sodium ion solution (800 mmol/l) (for 4 days),phenylephrine (5~50 ug/min) ,sodium nitroprusside (10~100 ug/min)