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Study IDStudyExperiment NameExperiment NotesStrain Ont IDStrainSexAge# of AnimalsSample NotesClinical Measurement Ont IDPhenotypeFormulaClinical Measurement NotesAverage TypeValueUnitsSEMSDMethod Ont IDMethodMethod SiteMethod DurationMethod NotesPost Insult TypePost Insult Time ValuePost Insult Time UnitConditionsRecord IDCondition 1Condition 2Condition 3
205Saad Y, et al., Hypertension. 2007arterial blood pressure traitRS:0000817SS/Jrmale84 days to 81 days9CMO:0000004systolic blood pressurerecorded every 5 minutes for 4 days213mmHg7.4722.41MMO:0000070intra-aortic abdominal radiotelemetryaorta345600.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 42 days)12072controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 42 days)
304Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901.arterial blood pressure traitRS:0000817SS/Jrmale78 days to 66 days21CMO:0000009mean arterial blood pressureaverage of 24 hour averages over 12 daysserial mean177mmHg6.027.4955MMO:0000070intra-aortic abdominal radiotelemetryabdominal aorta1036800.0telemetry probe model PA-D70, Data Sciences, St. Paul, MNcontrolled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days)12737controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (between 31 and 50 days)
261Grondin M, et al., Physiol Genomics 2005 Mar 21;21(1):112-6. Epub 2005 Jan 4.arterial blood pressure traitRS:0000817SS/Jrmale92 days to 88 days19CMO:0000009mean arterial blood pressuremeasure every 2 min for 24 hrs169mmHg4.017.4356MMO:0000070intra-aortic abdominal radiotelemetrycontrolled sodium content diet (2 %) (between 43 and 47 days)12422controlled sodium content diet (2 %) (between 43 and 47 days)
269Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.arterial blood pressure traitRS:0000817SS/Jrmale56 days10CMO:0000009mean arterial blood pressure175mmHg4.012.6491MMO:0000070intra-aortic abdominal radiotelemetryaortacontrolled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days)12544controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 21 days)
242Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 56 days10CMO:0000009mean arterial blood pressure170mmHg5.015.8114MMO:0000070intra-aortic abdominal radiotelemetrycontrolled sodium content diet (2 %) (between 21 and 37 days)12322controlled sodium content diet (2 %) (between 21 and 37 days)
242Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 56 days18CMO:0000009mean arterial blood pressure170mmHg4.016.9706MMO:0000070intra-aortic abdominal radiotelemetrycontrolled sodium content diet (2 %) (between 21 and 37 days)12354controlled sodium content diet (2 %) (between 21 and 37 days)
269Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.arterial blood pressure traitRS:0000817SS/Jrmale56 days16CMO:0000009mean arterial blood pressure184mmHg4.016.0MMO:0000070intra-aortic abdominal radiotelemetryaortacontrolled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days)12595controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 21 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale79 days to 75 days5CMO:0000005diastolic blood pressureaverage of 12 4-hour averages over 48 hours using 5 or 6 ratsserial mean130mmHg1.573.5106MMO:0000070intra-aortic abdominal radiotelemetrylower abdominal aorta172800C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (2 %) (between 35 and 37 days)13031controlled sodium content diet (2 %) (between 35 and 37 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale79 days to 75 days5CMO:0000009mean arterial blood pressureaverage of 12 4-hour averages over 48 hours using 5 or 6 ratsserial mean158mmHg1.763.9355MMO:0000070intra-aortic abdominal radiotelemetrylower abdominal aorta172800C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (2 %) (between 35 and 37 days)13035controlled sodium content diet (2 %) (between 35 and 37 days)
328Moujahidine M, et al., Mamm Genome 2002 Mar;13(3):153-6.arterial blood pressure traitRS:0000817SS/Jrmale71 days to 56 days11CMO:0000009mean arterial blood pressureaverage of 6 measurements taken every 4 hrsserial mean184mmHg5.016.5831MMO:0000070intra-aortic abdominal radiotelemetryaorta0controlled sodium content diet (2 %) (between 21 and 36 days)13078controlled sodium content diet (2 %) (between 21 and 36 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale79 days to 75 days5CMO:0000004systolic blood pressureaverage of 12 4-hour averages over 48 hours using 5 or 6 ratsserial mean185mmHg1.974.4051MMO:0000070intra-aortic abdominal radiotelemetrylower abdominal aorta172800C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (2 %) (between 35 and 37 days)13026controlled sodium content diet (2 %) (between 35 and 37 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.heart pumping traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000002heart ratediurnal difference390beats/min4.111.5966MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65503controlled sodium content diet (2 %) (between 34 and 38 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale69 days to 67 days5CMO:0000004systolic blood pressure181mmHg3.68.0498MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days)65041controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 27 and 28 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale78 days to 76 days5CMO:0000004systolic blood pressure217.9mmHg2.14.6957MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days)65044controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 9 and 10 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale109 days to 107 days3CMO:0000004systolic blood pressure228.2mmHg2.64.5033MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days)65047controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 39 and 40 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale116 days to 114 days3CMO:0000004systolic blood pressure219.3mmHg4.27.2746MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days)65050controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 47 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale149 days to 147 days1CMO:0000004systolic blood pressure219.7mmHg1.71.7MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days)65053controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 79 and 80 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale69 days to 67 days5CMO:0000005diastolic blood pressure125.2mmHg3.06.7082MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days)65057controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 27 and 28 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale78 days to 76 days4CMO:0000005diastolic blood pressure153mmHg1.63.2MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days)65060controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 9 and 10 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale109 days to 107 days3CMO:0000005diastolic blood pressure164.9mmHg2.33.9837MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days)65063controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 39 and 40 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale116 days to 114 days3CMO:0000005diastolic blood pressure158.2mmHg3.96.755MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days)65066controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 47 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale149 days to 147 days1CMO:0000005diastolic blood pressure152.5mmHg1.71.7MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days)65069controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 79 and 80 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000005diastolic blood pressureaverage of 24 hr147mmHg5.515.5563MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65494controlled sodium content diet (2 %) (between 34 and 38 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000292pulse pressureaverage of 24 hr52mmHg3.49.6167MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65495controlled sodium content diet (2 %) (between 34 and 38 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000004systolic blood pressureaverage of 24 hr199mmHg5.014.1421MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65493controlled sodium content diet (2 %) (between 34 and 38 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000009mean arterial blood pressureaverage of 24 hr172mmHg5.014.1421MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65496controlled sodium content diet (2 %) (between 34 and 38 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000607absolute change in systolic blood pressurediurnal difference22.6mmHg1.052.9698MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days) then controlled exposure to darkness then controlled exposure to ambient light65497controlled sodium content diet (2 %) (between 34 and 38 days)controlled exposure to darknesscontrolled exposure to ambient light
563Crespo K, et al., J Hypertens. 2011 Mar;29(3):460-5.arterial blood pressure traitRS:0000817SS/Jrmale73 days to 66 days14CMO:0000009mean arterial blood pressure178mmHg4.014.9666MMO:0000070intra-aortic abdominal radiotelemetry0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 49 days)65147controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (between 31 and 49 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart pumping traitRS:0000817SS/Jrmale79 days to 75 days5CMO:0000002heart rate378beats/min9.1820.5271MMO:0000070intra-aortic abdominal radiotelemetry172800controlled sodium content diet (2 %) (for 37 days)64986controlled sodium content diet (2 %) (for 37 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale50 days to 43 days0CMO:0000534absolute change in heart rate54beats/min6.0MMO:0000070intra-aortic abdominal radiotelemetry0.0sodium ion solution (800 mmol/l) (for 14 days)69698sodium ion solution (800 mmol/l) (for 14 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale50 days to 43 days0CMO:0000742percent change in heart rate10%1.0MMO:0000070intra-aortic abdominal radiotelemetry0.0sodium ion solution (800 mmol/l) (for 14 days)69702sodium ion solution (800 mmol/l) (for 14 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.arterial blood pressure traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0000533absolute change in mean arterial blood pressure23mmHg1.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours)69729sodium ion solution (800 mmol/l) (for 4 days)air-jet exposure (2 lb/in2) (for 0 hours)
344Huang BS, et al., Hypertension. 2007 Apr 9;.arterial blood pressure traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0002035percent change in mean arterial blood pressure% change map17%1.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours)69733sodium ion solution (800 mmol/l) (for 4 days)air-jet exposure (2 lb/in2) (for 0 hours)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0000534absolute change in heart rate45beats/min3.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours)69737sodium ion solution (800 mmol/l) (for 4 days)air-jet exposure (2 lb/in2) (for 0 hours)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0000742percent change in heart rate10%0.3MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours)69741sodium ion solution (800 mmol/l) (for 4 days)air-jet exposure (2 lb/in2) (for 0 hours)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0002037maximum change in heart rate to change in mean arterial blood pressure ratioMaximum slope, bpm/mm Hg-1.8beats/min/mmHg0.2MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5~50 ug/min) then sodium nitroprusside (10~100 ug/min) 69745sodium ion solution (800 mmol/l) (for 4 days)phenylephrine (5~50 ug/min) sodium nitroprusside (10~100 ug/min)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0002036change in heart rate to change in mean arterial blood pressure ratioaverage slope, bpm/mm Hg-1.6beats/min/mmHg0.2MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5~50 ug/min) then sodium nitroprusside (10~100 ug/min) 69749sodium ion solution (800 mmol/l) (for 4 days)phenylephrine (5~50 ug/min) sodium nitroprusside (10~100 ug/min)
830Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14.arterial blood pressure traitRS:0000817SS/Jrmale59 days to 56 days16CMO:0000009mean arterial blood pressure177mmHgMMO:0000070intra-aortic abdominal radiotelemetry86400.0controlled sodium content diet (2 %) (for 21 days)68086controlled sodium content diet (2 %) (for 21 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.arterial blood pressure traitRS:0000817SS/Jrmale51 days to 43 days0CMO:0000533absolute change in mean arterial blood pressure1min measurement per 30min, 24 hr average17mmHg2.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days)68138sodium ion solution (800 mmol/l) (for 4 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.arterial blood pressure traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0000533absolute change in mean arterial blood pressure1min measurement per 30min, 24 hr average13mmHg1.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 14 days)68142sodium ion solution (800 mmol/l) (for 14 days)